What do the HCD genes expressed by the the gram -ve P.aeruginosa do?
Increase pathogenicity
Allow biofilm formation
Cause a fibrin clot barrier
At HCD, P.aeruginosa produced which Homoserine Lactone?
LasI, which are detected by LasR
RhlI which are detected by RhlR
Mrl, which are detected by MrR
FasI, which are detected by FasR
The homoserine lactones of P. aeruginosa can be detected in the sputum of Cystic fibrosis patients
The strains of S.aureus produce 1 of 4 peptides
What is the role of each peptide produced by S.aureus?
Stimulates other strains that produce the same peptide
Inhibits other strains that produce the same peptide
Stimulates other strains that produce different peptides
Inhibits other strains that produce different peptides
P2 & P3 are divergent promoters (they go in opposite directions)
In E.Coli, of the P3 stimulated proteins, AgrA is the intracellular transducer,....
AgrB is the exit channel, AgrD is the autoinducer, AgrC is the receptor
AgrV is the exit channel, AgrC is the autoinducer, AgrD is the receptor
P2 transcribes RNAIII
RNAIII controls 100s of genes
RNAIII binds to the mRNA close to the ribosomal binding site, and does what?
Alters the secondary structure to inhibit/promote ribosomal binding
Alters the super- secondary structure to inhibit/promote ribosomal binding
Alters the tertiary structure to inhibit/promote ribosomal binding
