WBCs and Resistance to disease

Non-specific

Specific

2 Main categories of WBCs

Neutrophils

Eosinophils

Basophils

Lymphocytes

Monocytes

A macrophage extends a .............to pull in and engulf a bacterium.

Lymphatic System

Organs of the lymphatic system include?

Parts of the Lymphatic System - Lymph?

Lymphatic vessels (lymphatics)?

LYMPH NODES

Spleen

Thymus

Tonsils

Non-specific Resistance - Physical barriers

Chemical barriers

Natural Killer (NK)Cells

Interferons

Fever (pyrexia)

Summary of non-specific defences - 2nd line of defense?

Any foreign substance which triggers an immune response is called an ....... (e.g.bacteria, viruses, transplanted tissue, pollen ,etc)

Immune system remembers a particular antigen & responds much faster on 2nd exposure.
Immune system can recognise & remember millions of antigens that may invade body.
2 types of lymphocytes involved?

B- & T-cells are derived from ?

Immature T-cells must pass to the.......where they gain specificity.

B Cells provide?
Defend against?

T Cells provide?
Defend against?

Each T or B cell:
responds only to a ...... antigen
ignores all others

On exposure to specific antigens, .......are activated & transform into ...... cells which produce ......... which inactivate the antigen.

Antibodies are proteins-immunoglobulins

They are y-shaped molecules with specific receptor sites to bind specific antigen

Used to attack free bacteria & viruses in body fluids (i.e extracellular pathogens)

Cell-mediated immunity (T-cells)

Helper T-cells

Cytotoxic (killer) T-cells

Suppressor T-cells

Active Immunity

Passive Immunity