Wound edges are not opposed in healing by
Primary intention
Secondary intention
Which type of healing involves more granulation tissue?
Wound edges are opposed in what type of healing?
Which protein acts as a framework for cell growth during primary intention?
Fibrin
Fibrinogen
Collagen
Thrombin
Surface dehydration of a wound results in...
Scab formation
Scar formation
Blood clotting
As the blood clot disappears during healing by primary intention, what feature forms?
Dermal scar
Granulatory bundle
Fibrin mesh
Healing by primary intention:
The wound edges are brought close together so that there is a narrow incision. The wounded area fills with a which has a mesh that acts as a framework for cell growth. The surface of the wound dehydrates which forms a . There is inflammation around the edges of the wound. The epidermis thickens and grows along the cut edge of the dermis to meet in the midline. tissue grows into the blood clot that filled the wound space and this produces a scar.
The inflammatory reaction is less intense in healing by primary intention.
Wound contraction is higher in wounds healing by secondary intention.
Wound contraction is due to cells specifically known as...
Myofibroblasts
Fibroblasts
Tubuloblasts
Centrioblasts
If a wound is infected, surgeons will...
Try to close the wound so it heals by primary intention
Leave the wound to heal by secondary intention
Healed wounds eventually become as strong as normal skin.
Healed wounds don't get any stronger after approximately...
3 months
1 week
1 month
Healed wounds get stronger because of...
Cross-linking of collagen
Increased amount of collagen
Decreased amount of granulation tissue
Areas that have a greater blood supply will generally heal
Faster
Slower
Vitamin C deficiency interferes with
Collagen synthesis
Collagen degradation
Myofibroblast contraction
Moving a wound early on while it is healing can delay healing.
Wound dehiscence is an example of
Deficient scar formation
Excessive scar formation
Contraction
Keloid scarring is an example of
Contractions
Exuberant granulations occur when...
The granulation tissue grows faster than the epithelial covering
Fibroblasts proliferation is not regulated correctly
Excessive amounts of collagen are deposited by hyperactive fibroblasts
Aggressive fibromatoses are due to...
Which type of problem to do with wound repair is considered nearly malignant?
Aggressive fibromatoses
Exuberant granulations
Wound dehiscence
Label the diagram
Cytokines released in wound healing are similar to those in bone healing.
A bone fracture disrupts blood vessels. This results in...
Haematoma
Angiogenesis
Osteoblasts which help to deposit bone and repair fractures are sourced from where?
Bone ends
Periosteum
Spleen
Thymus
Deposition of the uncalcified matrix during bone healing anchors the bone ends but give structural rigidity. This is known as the tissue callus. When bone is deposited this forms teh callus and structural rigidity increases with time to allow weight to be put on the bone. Eventually the callus is remodelled and woven bone is replaced by bone with the m cavity being restored (bone marrow chamber).
The soft tissue callus is associated with
Woven bone
Lamellar bone
Uncalcified bone matrix
Select the statement that is true
Woven bone has collagen fibres randomly oriented whereas lamellar bone has collagen fibres arranged along lines of stress
Woven bone has collagen fibres oriented parallel whereas lamellar bone has collagen fibres arranged randomly
The soft tissue callus is associated with lamellar bone
Uncalcified bone matrix is deposited by osteoclasts which originate from the periosteum around the bone
Uncalcified bone matrix is also known as...
Osteoid
Osteoclast
Osteocyte
Osteoblast
Osteoma
Osteomatous matrix
Select the correct order from fracture to the healing of a bone fracture.
Haematoma -> Osteoid -> Woven bone -> Lamellar bone
Woven bone -> Lamellar bone -> Haematoma -> Osteoid
Osteoid -> Woven bone -> Haematoma -> Lamellar bone
Osteoid -> Haematoma -> Woven Bone -> Lamellar bone
Woven bone is a similar strength to lamellar bone.
Bone healing is quicker in
Children
Adults
Problems with bone healing:
D - due to malalignment when repositioning fracture
Soft tissue getting in between broken bone
Delayed union progressing to -union - fracture ends keep moving
Pseudo - cavity at the site of the fracture
Avascular - death of a section of bone due to is Osteo - especially in open fractures
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