Histoplasma capsulatum

Mycelial Form

Yeast Form

Pathogen Type

Transmission

H.c variant capsulatum- Location

H.c variant capsulatum- Infection

H.c variant duboisi- Location

H.c variant duboisi- Infection

Source

Infection- Inhalation

Infection- Conversion

Infection- Survival in Macrophages (Alpha-1,3-glycan)

Infection- Survival In Macrophages (Ca2+ Binding)

Infection- Survival In Macrophages (Lysosomes)

Infection- Multiplication

Low Infection Dose

High Infection Dose- Both

High Infection Dose- Fibrosis

High Infection Dose- Dissemination

High Infection Dose- capsulatum

High Infection Dose- gambiense

Treatment

Diagnosis-