The main enzymes targets for regulation in the krebs cycle are:
citrate synthase and fumarase
Aconitase, succinate dehydrogenase and fumarase
citrate synthase, isocitrate dehydrogenase and alpha ketoglutarate dehydrogenase
isocitrate dehydrogenase and alpha ketoglutarate dehydrogenase
Sodium fluoroacetate is...
part of the krebs cycle
an enzyme in the krebs cycle
A poison which disrupts the krebs cycle
Naturally in the body and is an activator of the krebs cycle
Beriberi is a vitamin C deficiency characterised by neurological and cardiac symptoms
Leigh's syndrome is a fatal neurodegenerative disorder caused by inherited faults in oxidative phosporylation. The pathology of the disease is bilateral lesions. Where are these found?
thalamus, Basal ganglia and brain stem and spinal cord
thalamous, Basal ganglia and brain stem
brain stem, basal ganglia and spinal cord
spinal cord and brain stem
Electrons used in oxidative phosphorylation come from...?
NADH
FADH2
NADH and FADH2
The cytosol of the mitochondrion
Complex two pumps out 2 hydrogen ions for every 2 electrons
The krebs cycle can be regulated by hormones
What is Beriberi?
A vitamin C deficiency- characterised by neurological and cardiac symptoms
A vitamin b1 deficiency- characterised by neurological and cardiac symptoms
A vitamin b1 deficiency- characterised by muscle wasting
A vitamin C deficiency- characterised by muscle wasting
The main target for regulation in the krebs cycle is on the reactions that are reversible
The PDH is inactive when bound to phosphate
The PDH is required in the krebs cycle for the following reaction to take place; oxaloacetate+ acetyl CoA ---> citrate
Which of the following are the steps which are regulated in glycolysis?
glucose to glucose-6-phosphate
glucose-6-phosphate to fructose-6-phosphate
fructose-6-phosphate to fructose-1,6-bisphosphate
3-phosphoglycerate to 2-phosphoglycerate
phosphoenolpyruvate to pyruvate
Arsenate will substitute for phosphate in 3- phosphoglycerate
Arsenate is a bad because it makes the net ATP production from the krebs cycle be 0
The net ATP production of glycolysis is 2
