11677938
Descrição
Quiz por Melanie Grynsztejn, atualizado more than 1 year ago
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Criado por Melanie Grynsztejn
quase 7 anos atrás
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Questão 1
Questão
Which beta blockers block both beta & alpha receptors?
Responda
-
Labetol
-
Carvedilol
-
Propanolol
-
Metroprolol
Questão 2
Questão
Beta‐1, found primarily in [blank_start]heart muscle[blank_end], results in increased heart rate, contractility, and atrioventricular (AV) conduction
Responda
-
heart muscle
-
bronchial & peripheral smooth muscle
-
adipose
Questão 3
Questão
Beta‐2, found in [blank_start]bronchial and peripheral vascular[blank_end] smooth muscle; results in vasodilatation and bronchodilation.
Responda
-
bronchial and peripheral vascular
-
heart muscle
-
adipose
Questão 4
Questão
Beta‐3, found in [blank_start]adipose tissue and the heart;[blank_end] may reduce cardiac contractility.
Responda
-
adipose tissue and the heart;
-
heart muscle
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bronchial and peripheral vascular smooth
Questão 5
Questão
Beta blockers MOA:
Responda
-
Competitively inhibiting catecholamines from binding to these receptors.
-
Dilate veins, arteries, and coronary arteries by relaxing vascular smooth muscle
-
Act on vascular smooth muscle to reduce contraction of the arteries and cause vasodilation
Questão 6
Questão
Which of the following Beta Blockers are eliminated by hepatic metabolism and are lipid soluble
Responda
-
Propranolol
-
Metoprolol
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Atenolol
-
Sotalol
Questão 7
Questão
Why is important to know which BB are eliminated by hepatic metabolism and more lipid soluble?
Responda
-
Enter CNS in high concentrations, possibly resulting in an increased incidence of CNS side effects
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Are eliminated and do not as readily enter the CNS so can be prescribed more readily
-
Can cause hepatic damage if prescribed in too high a dosage
Questão 8
Questão
Which of the following beta blockers are excreted unchanged by the kidney?
Responda
-
Atenolol
-
Sotalol
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Propranolol
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Metoprolol
Questão 9
Questão
Metoprolol tartrate is [blank_start]shorter‐acting[blank_end] and dose [blank_start]*twice*[blank_end] daily and
Metoprolol succinate [blank_start]longer‐ acting[blank_end] and dosed [blank_start]*once*[blank_end] daily
Responda
-
shorter‐acting
-
longer-acting
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*twice*
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*once*
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longer‐ acting
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shorter-acting
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*once*
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*twice*
Questão 10
Questão
Atenolol and sotalol are more water soluble and are eliminated unchanged by the kidney. What is the effect of this on plasma half-lives & bioavailability?
Responda
-
Longer plasma half-life
-
Shorter plasma half-life
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Greater bioavailability
-
Lesser bioavailability
Questão 11
Questão
True or False:
BB are first-line therapy to reduce angina episodes & increase exercise tolerance
Responda
- True
- False
Questão 12
Questão
BB & CCB are antianginal drugs proven to prevent reinfarction and improve survival in patients who have sustained a MI
Responda
- True
- False
Questão 13
Questão
BB should NOT be used in which type of angina patient
Responda
-
Stable
-
Unstable
-
Vasospastic (Prinzmetal)
Questão 14
Questão
It is important to [blank_start]taper[blank_end] BB when discontinuing BB therapy
Responda
-
taper
Questão 15
Questão
What are some potential Adverse Effects of Beta Blockers
Responda
-
Decreased heart rate, contractility & AV node conduction
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Increased heart rate, contractility & AV node conduction
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Bronchoconstriction
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Bronchodilation
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Nightmares, Insomnia, hallucinations
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Depression
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Weight loss
-
Weight gain
-
Erectile dysfunction
Questão 16
Questão
T or F
CCB are less effective than BB when treating stable angina
Responda
- True
- False
Questão 17
Questão
When are CCB used to treat stable angina?
Responda
-
When BB is not successful
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When BB is contraindicated
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When BB are causing SE
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Are never combined with BB
Questão 18
Questão
What is the caution for using both non‐dihydropyridine and BB?
Responda
-
Additive bradycardia
-
Orthostatic hypotension
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Weakness
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N/V/D
Questão 19
Questão
CCB improve anginal symptoms by causing coronary and [blank_start]peripheral[blank_end] vasodilatation and [blank_start]reducing[blank_end] contractility
Responda
-
peripheral
-
central
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reducing
-
increasing
Questão 20
Questão
Select the non-dihydropyridine CCB:
Responda
-
Diltiazem
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Verapamil
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Amlodipine
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Felodipine
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Nifedipine
Questão 21
Questão
Which types of CCB are preferred for angina
Responda
-
Long-acting non-dihydropyridine CCB - Verapamil & Diltiazem
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Second generation CCB - Amlodipine or Felodipine
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1st generation CCB - Nifidepine
Questão 22
Questão
What is the most concerning adverse effect of dihyrdropyridine (amlodipine, felodipine, nifedipine
Responda
-
Peripheral edema
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Lightheadedness
-
Flushing
Questão 23
Questão
What are potential adverse effects of Dihydropyridines
Responda
-
Constipation
-
Bradycardia
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Peripheral edema
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Lightheadness
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Flushing
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Headache
Questão 24
Questão
What are potential adverse effects of non-dihydropyridines
Responda
-
Bradycardia
-
Constipation
-
Peripheral edema
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Headache
-
Lightheadedness
-
Flushing
Questão 25
Questão
What are a prescribers options if a patient gets peripheral edema on a dihydropyridines?
Responda
-
Reduce dose
-
Add an angiotensin‐converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB)
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Switch to a non‐dihydropyridine agent
-
Add a metered dose spray nitrate
Questão 26
Questão
MOA for nitrate used for stable angina is
Responda
-
Dilate veins, arteries, and coronary arteries by relaxing vascular smooth muscle.
-
Competitively inhibiting catecholamines from binding to these receptors.
-
Act on vascular smooth muscle reducing contraction of the arteries and causing vasodilation
Questão 27
Questão
Select the cardioselective beta blockers
Responda
-
Atenolol
-
Metoprolol
-
Propranolol
Questão 28
Questão
Select the non-cardioselective beta blockers
Responda
-
Meoprolol
-
Atenolol
-
Propranolol
Questão 29
Questão
Nitrates are used as
Responda
-
First‐line therapy for the treatment of acute anginal
-
Prophylactically for activities known to elicit angina
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Ongoing management of stable angina
Questão 30
Questão
Usually in the form of a sublingual preparation, nitrates onset of action is within [blank_start]2‐5 minutes[blank_end] and duration of action [blank_start]15‐30 minutes[blank_end]
Responda
-
2‐5 minutes
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5 - 10 minutes
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1 - 2 minutes
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15 ‐ 30 minutes
-
5 - 10 minutes
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10 - 20 minutes
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15 - 20 minutes
Questão 31
Questão
Select the potential adverse effects of nitrates
Responda
-
Hypotension
-
Flushing
-
Bradycardia
-
Headache
-
N/V/D
-
LIghtheadedness
Questão 32
Questão
American College of Cardiology/American Heart Association (ACC/AHA) guidelines for calling the emergency services are
Responda
-
Contact EMS if chest pain or discomfort is unimproved or worsening 5 minutes after *one* nitroglycerin dose has been taken sublingually
-
Take one nitroglycerin dose sublingually every 5 minutes for up to *3 doses* before calling for emergency medical services evaluation.
Questão 33
Questão
Nitroglycerin tablets are both [blank_start]heat[blank_end] and [blank_start]light[blank_end] sensitive
Responda
-
heat
-
light
Questão 34
Questão
Nitroglycerin tablets should be stored in a tightly capped dark bottle in the refrigerator with only a small supply being carried by the patient and discarded after 12 months
Responda
- True
- False
Questão 35
Questão
The following are longer-acting nitrate therapies
Responda
-
Nitroglycerin table
-
Isosorbide dinitrate
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Isosorbide mononitrate
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Transdermal nitroglycerin patch
Questão 36
Questão
How can a patient address the issue of nitrate tolerance with long-term therapies like the transdermal nitroglycerin patch?
Responda
-
Nitrate‐free interval (at least approx 8‐10 hours)
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Use patch on different sites on the body
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Increase dosage of transdermal patch
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Switch to short-term nitroglycerin tablet
Questão 37
Questão
What is a REALLY IMPORTANT nitrate contraindication drug
Responda
-
Warfarin (Coumadin)
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Erectile dysfunction drugs, PDE-5, Sildenafil, Vardenafil or Tadalafil within 24 hours
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Second generation dihydropyridine CCB drugs Amlodipine and Felodipine
-
Cardioselective BB drugs Atenolol and Metoprolol
Questão 38
Questão
Ranolazine is a new drug for stable angina that is recommended for patients that have failed all other antianginal therpies. However, it is contraindicated for the following patients
Responda
-
Pre-existing QT interval
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Hepatic disease
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Renal disease
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Tachycardia
Questão 39
Questão
The following are angina PREVENTIVE therapies
Responda
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ASA
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Clopidogrel (Plavix) if allergic to aspirin
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Verapamil if allergic to aspirin
-
Propranolol if allergic to aspiring
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