Parkinsons epidemiology: prevalence is [blank_start]0.5-1[blank_end]% in the UK in >[blank_start]60[blank_end]'s. it is the second most common neurodegenerative disorder after alzeheimers. the mean age of onset is [blank_start]45-60[blank_end] but it can occur in people as young as [blank_start]30[blank_end]. there are [blank_start]120,000[blank_end] people living with parkinsons in the UK.
Responda
0.5-1
1-1.5
1.5-2
2-2.5
60
50
70
80
45-60
50-65
55-70
60-75
30
20
25
35
120,000
100,000
80,000
140,000
Questão 2
Questão
which of the following is not a cause of parkinsons
Responda
heavy metal exposure
pesticide exposure
repeated head trauma
idiopathic
MPTP
genetics
excessive alcohol
Questão 3
Questão
parkinsons results from the loss of [blank_start]dopaminergic neurons[blank_end] in the [blank_start]basal ganglia[blank_end] most notably the [blank_start]substantia nigra[blank_end] which usually synthesises [blank_start]dopamine[blank_end]. surviving neutrons contain aggregations of protein ([blank_start]alpha-synuclein[blank_end]) called [blank_start]lewy bodies[blank_end]. symptoms are only seen once levels of dopamine are [blank_start]20-40%[blank_end] of normal. the disease is slowly progressive without remission.
Responda
dopaminergic neurons
basal ganglia
substantia nigra
dopamine
alpha-synuclein
lewy bodies
20-40%
Questão 4
Questão
which of the following is not part of the classic triad for parkinsons?
Responda
tremor
rigidity
bradykinesia
ataxic gait
Questão 5
Questão
which of the following is not a symptom of parkinsons?
Responda
loss of sense of smell
slurred slow speech
plain face
depression
dementia
hallucinations
REM sleep disturbance
difficulty swallowing
sluggish bowel and bladder
vertical gaze palsy
Questão 6
Questão
what is the name of the scan that can be used to diagnose dementia? [blank_start]DAT[blank_end]
Responda
DAT
Questão 7
Questão
mark on the DAT scan which is normal and which is abnormal
what is the name of the criteria that can be helpful is diagnosing parkinsons? [blank_start]brain bank[blank_end]
Responda
brain bank
Questão 9
Questão
In younger patients you would start by treating them with L-dopa instead of dopamine agonists
Responda
True
False
Questão 10
Questão
match each of the following types of parkinsons medication to the examples:
l-dopa - [blank_start]madapar[blank_end]
selective dopamine agonist - [blank_start]pramipexole[blank_end], [blank_start]bromocriptine[blank_end]
increases dopamine release - [blank_start]amantadine[blank_end]
MAO-B inhibitors - [blank_start]selegilene[blank_end]
COMTI - [blank_start]tolcapine[blank_end]
Responda
madapar
pramipexole
bromocriptine
amantadine
selegilene
tolcapine
Questão 11
Questão
never prescribe haloperidol for a parkinsons patients
Responda
True
False
Questão 12
Questão
which of the following is not a treatment for parkinsons?
Responda
L-dopa
pramipexole
bromocriptine
COMTI
MAOB-I
apomorphine
duodopa
surgery
amantadine
tamsulosin
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