Pharmacology- Fluoroquinolones- 4th Year PMU

Descrição

Pharmacology- Fluoroquinolones- 4th Year PMU
Med Student
Quiz por Med Student , atualizado more than 1 year ago
Med Student
Criado por Med Student quase 6 anos atrás
101
3

Resumo de Recurso

Questão 1

Questão
Fluoroquinoiones are:
Responda
  • Gentamycin
  • Moxifloxacin
  • Ciprofloxacin
  • Levofloxacin

Questão 2

Questão
Mechanism of action of quinolones is:
Responda
  • inhibition of protein synthesis
  • inhibition of cell wall synthesis
  • inhibition of topoisomerase II and IV
  • inhibition of DNA transcription and replication

Questão 3

Questão
Fluoroquinolones have:
Responda
  • broad antibacterial spectrum
  • narrow antibacterial spectrum
  • bacteriostatic effect
  • bactericidal effect

Questão 4

Questão
Point out the correct statements for pharmacokinetics of fluoroquinolones:
Responda
  • bad oral absorption and are administered always parenterally
  • distribute well into all tissues and body fluids
  • inhibit some liver cytochromes
  • most of them are excreted renally

Questão 5

Questão
Fluoroquinolones are used for treatment of:
Responda
  • Urinary tract infections
  • Respiratory infections
  • Skin infections
  • Gl infections

Questão 6

Questão
Adverse drug reactions of fluoroquinolones are:
Responda
  • articular cartilage erosion (arthropathy)
  • hypertension
  • seizures in patients with epilepsy
  • prolongation of QT interval

Questão 7

Questão
Quinolones are contraindicated in
Responda
  • pregnancy and breast-feeding
  • children under 18 years of age
  • patients with epilepsy
  • patients with renal failure

Questão 8

Questão
Drug interactions of fluoroquinolones are:
Responda
  • increase serum levels of theophyiline by inhibiting its metabolism
  • decrease serum levels of theophyiline by inducing its metabolism
  • synergism with beta-lactams
  • calcium and other divalent cations decrease their absorption

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