15623480
Descrição
Quiz por Med Student , atualizado more than 1 year ago
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Criado por Med Student
aproximadamente 6 anos atrás
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Questão 1
Questão
Antifungals are:
Responda
-
tetracyclines
-
imidazoles
-
echinocandims
-
triazols
Questão 2
Questão
Synthetic antifungal drugs are
Responda
-
Nystatin
-
Itraconazole
-
Ketoconazole
-
Fluconazole
Questão 3
Questão
Antifungal antibiotics are:
Responda
-
Nystatin
-
Tetracycline
-
Gentamycin
-
Amphotericin B
Questão 4
Questão
Azoles:
Responda
-
are fungistatic
-
inhibit cell wall synthesis
-
inhibit ergosterol synthesis
-
inhibit hepatic CYP450 enzymes
Questão 5
Questão
lmidazoles are:
Responda
-
Fluconazole and ltraconazole
-
Miconazole and Econazole
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Given topically
-
Given systematically
Questão 6
Questão
Ketoconazole is:
Responda
-
the only imidazole that can be given orally
-
used for treatment of bacterial skin infections
-
used topically for cutaneous fungal infections
-
used intravenously for treatment of systemic fungal infections
Questão 7
Questão
Fluconazole:
Responda
-
it is non- steroidal anti-inflammatory drug
-
is triazole antifungal drug
-
is administered orally or intravenously
-
is excreted mainly unchanged with the urine
Questão 8
Questão
ADRs of azole antifungals are:
Responda
-
hepatotoxicity
-
endocrine disorders
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nephrotoxicity
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nausea, vomiting
Questão 9
Questão
Point the correct statements for Nystatin:
Responda
-
has fungistatic activity
-
causes gastrointestinal disturbances
-
is effective against Trichomonas vaginalis
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is effective against Candida species
Questão 10
Questão
ADRs of Amphoteracin B are:
Responda
-
renal impairment
-
hypokalemia
-
hypotension
-
liver impairment
Questão 11
Questão
Antiviral drugs act by following mechanisms
Responda
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inhibition of viral “uncoating”
-
inhibition of viral DNA or RNA synthesis
-
inhibition of viral proteases
-
inhibition of viral penetration into the cell
Questão 12
Questão
Point out the correct statements for Aciclovir:
Responda
-
it inhibits viral DNA polymerase
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it is used for “treatment of herpesvirus infections
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it inhibits neuraminidase enzyme
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can be applied topically, orally or intravenously
Questão 13
Questão
ADRs of Aciclovir are:
Responda
-
hepatotoxicity
-
renal impairment
-
local irritation
-
encephalopathy (at high i.v. doses)
Questão 14
Questão
Drugs for prevention and treatment of flu are:
Responda
-
Aciclovir (Zovirax)
-
Amantadin (Symmetrel)
-
Rimantadin (Flumadine)
-
Oseltamivir (Tamiflu)
Questão 15
Questão
Mechanism of action of Oseltamivir (Tamiflu) is
Responda
-
interference with the function of the viral M2 protein
-
inhibition of specific neuraminidase enzyme
-
inhibition of reverse transcriptases
-
inhibition of proteases
Questão 16
Questão
For Amantadine and Rimantadine is true:
Responda
-
resistance can develop rapidly
-
they are effective against both type A and type B influenza
-
they are effective against type A influenza viruses
-
they interfere with the function of the viral M2 protein and block uncoating of the Virus particles
Questão 17
Questão
Mechanisms of action of drugs for treatment of HIV infection are:
Responda
-
inhibition of reverse transcriptase
-
inhibition of HIV protease
-
inhibition of HIV entry into the host cell
-
inhibition of the insertion of proviral DNA. into the host cell genome
Questão 18
Questão
Point out the correct statements for Zidovudin;
Responda
-
it blocks HIV reverse transcriptase
-
it blocks HIV protease
-
it is a nucleoside analogue
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it can cause anemia and neutropenia
Questão 19
Questão
ADRS of Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs) are:
Responda
-
peripheral neuropathy
-
pancreatitis
-
polymyositis
-
glaucoma
Questão 20
Questão
HIV protease inhibitors are:
Responda
-
Zidovudin
-
Indinavir
-
Ritonavir
-
Aciclovir
Questão 21
Questão
For HIV protease inhibitors is true:
Responda
-
protease inhibition prevents maturation of the viral particles
-
they are enzyme inducers
-
they are enzyme inhibitors
-
they are combined with other antiretroviral drugs in the treatment of HIV infection
Questão 22
Questão
ADRs of HIV protease inhibitors are:
Responda
-
hyperlipidaemia
-
insulin resistance and hyperglycaemia
-
hypoglycaemia
-
fat redistribution
Questão 23
Questão
Inhibitor of both hepatitis B virus (HBV) and HIV reverse transcriptases is:
Responda
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Zidovudin
-
Lamivudin
-
Aciclovir
-
lndinavir
Questão 24
Questão
Protease inhibitor for treatment of chronic hepatitis C infection is:
Responda
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Aciclovir
-
Telaprevir
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Zidovudin
-
Oseltamivir
Questão 25
Questão
Antimycobacterial drugs are:
Responda
-
Rifampicin
-
Isoniazid
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Ethambutol
-
Amoxicillin
Questão 26
Questão
Rifampicin (Rifampin):
Responda
-
is bactericidal antibiotic with antimycobacterial activity
-
is antiviral drug
-
is broad spectrum antibiotic
-
is enzyme inducer
Questão 27
Questão
Mechanism of action of Rifampicin (Rifampin) is
Responda
-
inhibition of cell wall synthesis
-
inhibition of 50 S ribosomal subunit
-
inhibition of DNA-dependent RNA polymerase
-
increased cell membrane permeability
Questão 28
Questão
ADRs of Rifampicin (Rifampin) are:
Responda
-
heart failure
-
orange-red color of urine and other secretions
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hepatotoxicity
-
hypoglycaemia
Questão 29
Questão
Point out the correct statements for lsoniazid:
Responda
-
inhibits the synthesis of essential for mycobacteria mycolic acid
-
it is metabolized by, acetylation
-
it is specific for treatment of M. Tuberculosis
-
it is active against broad spectrum of bacteria
Questão 30
Questão
ADRs of lsoniazld are:
Responda
-
renal impairment
-
peripheral neuropathy
-
convulsions
-
hepatitis
Questão 31
Questão
lsoniazid-induced peripheral neuropathy can be avoided by:
Responda
-
supplementation with vitamin B1
-
supplementation with vitamin A
-
supplementation with vitamin B6
-
supplementation with vitamin B12
Questão 32
Questão
ADRs of Pyrazinamide are:
Responda
-
hepatotoxicity
-
arrhythmia
-
hyperuricaemia
-
hypoglycaemia
Questão 33
Questão
Ethambutol:
Responda
-
is bacteriostatic antimycobacterial drug
-
may cause liver failure
-
may cause optic neuritis
-
inhibits synthesis of the mycobacterial cell wall
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