Questão 1
Questão
Centrally-acting skeletal muscle relaxants are basically Central Nervous System depressants.
Questão 2
Questão
Direct-acting skeletal muscle relaxants affect:
Questão 3
Questão
Neuromuscular blocking drugs work by:
Responda
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a. disrupting nerve impulses at motor end plates
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b. disrupting nerve impulses at post-synaptic neurons
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c. both the above are true
Questão 4
Questão
Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.
Questão 5
Questão
The ________________ is that area where a terminal nerve ending innervates a muscle.
Questão 6
Questão
Curare alkaloids:
Responda
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Paralyze the diaphragm preventing breathing
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cross the blood-brain-barrier
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make one go unconscious immediately
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compete with phosphorus involved in muscle contractions
Questão 7
Questão
The antidote for curare alkaloids are ____________ drugs.
Responda
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anti-cholinesterase
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cholinesterase
Questão 8
Questão
Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.
Questão 9
Questão
Succinylcholine is metabolized slower than acetylcholine, resulting in:
Questão 10
Questão
What are the movement disorders associated with Parkinson's disease?
Questão 11
Questão
Akinesia is the absence of:
Questão 12
Questão
The 2 types of therapy for Parkinson's disease are _____________ and ______________ drugs.
Responda
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anti-cholinergic; dopaminergic
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anti-cholinergic; anti-cholinesterase
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cholinergic; dopaminergic
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cholinergic; anti-cholinersterase
Questão 13
Questão
Anti-cholinergic drugs inhibit acetylcholine action at parasympathetic receptors.
Questão 14
Questão
Too much acetylcholine will excite the CNS causing parkinsonian tremor.
Questão 15
Questão
Dopaminergic drugs act on the brain to improve motor function.
Questão 16
Questão
Dopaminergic drugs act on the brain to improve motor function.
Questão 17
Questão
Lavodopa can convert to dopamine:
Responda
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a. before crossing the blood-brain-barrier
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b. after crossing the blood-brain-barrier
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c. both the above are true
Questão 18
Responda
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a. Catechol-O-methyltransferase
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b. Catechol-OH-methyltransacetylase
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c. Catecholamine-O-methyltransacetylase
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d. none of the above are correct
Questão 19
Questão
Another name of 5-HT1-receptor agonists is triptans.
Questão 20
Questão
5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:
Responda
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migraines
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musculoskeletal issues
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seizures
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Parkinson's disease
Questão 21
Questão
Depolarizing neuromuscular blocking drugs act like ____________.
Responda
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acetylcholine
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norepinephrine
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epinephrine
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dopamine
Questão 22
Questão
Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.
Questão 23
Questão
Direct-acting skeletal muscle relaxants interfere with ___________ ions involved in skeletal muscle contraction:
Responda
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sodium
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calcium
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magnesium
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phosphorus
Questão 24
Questão
Parkinson's disease:
Responda
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a. has a deficiency of dopamine
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b. has an excess of acetylcholine
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c. is a movement disorder
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d. all the above are true
Questão 25
Questão
Another name for anti-cholinergic drugs is ____________ drugs.
Responda
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parasympatholytic
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sympatholytic
Questão 26
Questão
COMT inhibitors are reversible.
Questão 27
Questão
Triptans are used to treat:
Responda
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seizures
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musculoskeletal issues
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Parkinson's disease
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migraines
Questão 28
Questão
Abortive anti-migraine drugs are designed to stop a migraine:
Questão 29
Questão
Levodopa needs passage through the blood-brain-barrier to become effective.
Questão 30
Questão
Carbidopa enhances the effectiveness of Levodopa by preventing its peripheral conversion to dopamine.
Questão 31
Questão
COMT inhibitors are used in Parkinson patients when the initial therapy begins to wear off.
Questão 32
Questão
Contraindication for taking triptans includes:
Questão 33
Questão
Anti-cholinergic drugs inhibit acetylcholine action at sympathetic receptors.
Questão 34
Questão
For epilepsy and seizures a(an) ______________ drug is usually recommended.
Responda
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a. anti-migraine
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b. COMT inhibitor
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c. dopaminergic
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d. anti-convulsant
Questão 35
Questão
To have a higher conversion to dopamine after passing through the blood-brain-barrier, one needs to take ______________.
Questão 36
Questão
Anti-convulsant drugs:
Responda
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a. Stabilize nerve cells from over excitement
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b. Elevate seizure thresholds
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c. Inhibit neuromuscular transmission
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d. Increase GABA
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e. All the above are correct
Questão 37
Questão
The neurotransmitter released at motor end plates is:
Responda
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a. Norepinephrine
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b. Dopamine
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c. Acetylcholine
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d. Epinephrine
Questão 38
Questão
The effectiveness of ergotamine preparations is increased by drinking coffee.