Questão 1
Questão
According to their mechanism of action the adrenergic agonists can be divided in:
Questão 2
Questão
α1-adrenoceptors are located on:
Questão 3
Questão
β1-adrenoceptors are located on:
Responda
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postsynaptic neuronal endings
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presynaptic neuronal endings
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myocardial cells
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juxtaglomerular apparatus in the kidney
Questão 4
Questão
β2-adrenoceptors are located on:
Questão 5
Questão
β3-adrenoceptors are located in:
Questão 6
Questão
Pharmacological effects of Epinephrine are:
Responda
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positive chronotropic effect
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blood pressure elevation
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bronchial smooth muscles dilation
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elevated levels of blood sugar
Questão 7
Questão
Indications for the clinical use of Epinephrine are:
Questão 8
Questão
Potential adverse drug reactions of Epinephrine are:
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hypoglycaemia
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arrhythmia
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tremor
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anxiety and restlessness
Questão 9
Questão
Clinical indications for prescribing α1-agonists are:
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arterial hypotension
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acute rhinitis
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asthma attack
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heart block
Questão 10
Questão
Pharmacological effects of the selective β2-agonists are:
Questão 11
Questão
Which of the following drugs are selective β2-agonists?
Responda
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lsoprenalini sulfas
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Orciprenalini sulfas
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Salbutamol
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Salmeterol
Questão 12
Questão
β2-agonists are indicated in:
Responda
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bronchial asthma
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digitalis intoxication
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arterial hypertension
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threatening abortion
Questão 13
Questão
Adverse drug reactions of β2-agonists are:
Responda
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finger tremor
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bronchial dilatation
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hyperglycemia
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tolerance
Questão 14
Questão
What are the main features of the indirect-acting adrenergic agonists?
Responda
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stimulation of central nervous system
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drug tolerance and dependence
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have no effect on the cardio-vascular system
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used for treatment of narcolepsy and attention deficiency hyperactivity disorder (ADHD)
Questão 15
Questão
Clinically desirable interactions can occur between β2-agonists and:(find correct answer)
Questão 16
Questão
Mechanisms of action of the presynaptic adrenolytics are:
Responda
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blockade of the presynaptic α2-receptors
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activation of the presynaptic α2-receptors
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conversion to a “false“ neurotransmitter
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blockade of the phosphodiesterase enzyme
Questão 17
Questão
Which of the following drugs act as agonists of the presynaptic α2-adrenoceptors?
Responda
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Salbutamol
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Clonidini hydrochloridum
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α-Methyldopum (Dopegyt)
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Sotalol
Questão 18
Questão
Pharmacological effects of Clonidin are:
Questão 19
Questão
Adverse drug reactions of Clonidin are:
Questão 20
Questão
For Methyldopa is true:
Responda
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has antihypertensive effect
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it is safe in pregnancy
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could cause drug-induced parkinsonism
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used to treat threatening abortion
Questão 21
Questão
Which of the following drugs are α1-adrenoblockers?
Responda
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Prazosin
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Doxazosin
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Clonidin
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Chlorpromazin
Questão 22
Questão
Pharmacological effects of Prazosin are:
Questão 23
Questão
Adverse drug reactions of α1-adrenoblockers are:
Responda
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orthostatic collapse
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hypokalemia
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fluid retention
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hypoglycaemia
Questão 24
Questão
Which of the following drugs are non-selective β-blockers?
Responda
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Atenolol
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Pindolol
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Acebutolol
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Propranolol
Questão 25
Questão
Which of the following drugs are selective β1-blockers?
Responda
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Atenolol
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Pindolol
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Propranolol
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Metoprolol
Questão 26
Questão
β-blockers are indicated in case of:
Responda
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hypertension
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bronchial asthma
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arrhythmia
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ischaemic heart disease
Questão 27
Questão
Pharmacological effects of B-blockers are:
Responda
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bronchodilation
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negative inotropic effect
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positive chronotropic effect
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negative chronotropic effect
Questão 28
Questão
β-blocker approved for topical use in treatment of glaucoma is:
Responda
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Bisoprolol
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Metoprolol
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Timolol
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Propranolol
Questão 29
Questão
When applied topically in the eye the B-blocker Timolol will:
Questão 30
Questão
Potential adverse drug reactions of β-blockers are.
Responda
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hypoglycaemia
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bronchoconstriction
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hyperglycaemia
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nightmares
Questão 31
Questão
For long-term treatment with β-blockers is true:
Responda
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up-regulation of B-adrenergic receptors
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down-regulation of B-adrenergic receptors
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the therapy should be ceased abruptly
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the therapy should not be ceased abruptly