Adrenegic Drugs- Pharmacology 4th Year- PMU

Descrição

Adrenegic Drugs- Pharmacology 4th Year- PMU
Med Student
Quiz por Med Student , atualizado more than 1 year ago
Med Student
Criado por Med Student aproximadamente 6 anos atrás
91
3

Resumo de Recurso

Questão 1

Questão
According to their mechanism of action the adrenergic agonists can be divided in:
Responda
  • direct agonists
  • indirect agonists
  • agonists with mixed mechanism of action
  • natural compounds

Questão 2

Questão
α1-adrenoceptors are located on:
Responda
  • presynaptic neuronal endings
  • postsynaptic neuronal endings
  • blood vessels
  • iris dilator muscle

Questão 3

Questão
β1-adrenoceptors are located on:
Responda
  • postsynaptic neuronal endings
  • presynaptic neuronal endings
  • myocardial cells
  • juxtaglomerular apparatus in the kidney

Questão 4

Questão
β2-adrenoceptors are located on:
Responda
  • postsynaptic neuronal endings
  • bronchial smooth muscles
  • liver
  • uterus (womb)

Questão 5

Questão
β3-adrenoceptors are located in:
Responda
  • adipose tissue
  • urinary bladder
  • presynaptic neuronal endings
  • bronchial smooth muscles

Questão 6

Questão
Pharmacological effects of Epinephrine are:
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  • positive chronotropic effect
  • blood pressure elevation
  • bronchial smooth muscles dilation
  • elevated levels of blood sugar

Questão 7

Questão
Indications for the clinical use of Epinephrine are:
Responda
  • anaphylactic shock
  • hypoglycaemia
  • arrhythmia
  • glaucoma with wide iridocorneal angle

Questão 8

Questão
Potential adverse drug reactions of Epinephrine are:
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  • hypoglycaemia
  • arrhythmia
  • tremor
  • anxiety and restlessness

Questão 9

Questão
Clinical indications for prescribing α1-agonists are:
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  • arterial hypotension
  • acute rhinitis
  • asthma attack
  • heart block

Questão 10

Questão
Pharmacological effects of the selective β2-agonists are:
Responda
  • pupillary dilation
  • bronchial dilation
  • blood pressure elevation
  • relaxation of uterine muscle

Questão 11

Questão
Which of the following drugs are selective β2-agonists?
Responda
  • lsoprenalini sulfas
  • Orciprenalini sulfas
  • Salbutamol
  • Salmeterol

Questão 12

Questão
β2-agonists are indicated in:
Responda
  • bronchial asthma
  • digitalis intoxication
  • arterial hypertension
  • threatening abortion

Questão 13

Questão
Adverse drug reactions of β2-agonists are:
Responda
  • finger tremor
  • bronchial dilatation
  • hyperglycemia
  • tolerance

Questão 14

Questão
What are the main features of the indirect-acting adrenergic agonists?
Responda
  • stimulation of central nervous system
  • drug tolerance and dependence
  • have no effect on the cardio-vascular system
  • used for treatment of narcolepsy and attention deficiency hyperactivity disorder (ADHD)

Questão 15

Questão
Clinically desirable interactions can occur between β2-agonists and:(find correct answer)
Responda
  • tricyclic antidepressants
  • inhaled corticosteroids
  • inhaled antimuscarinic drugs
  • beta blockers

Questão 16

Questão
Mechanisms of action of the presynaptic adrenolytics are:
Responda
  • blockade of the presynaptic α2-receptors
  • activation of the presynaptic α2-receptors
  • conversion to a “false“ neurotransmitter
  • blockade of the phosphodiesterase enzyme

Questão 17

Questão
Which of the following drugs act as agonists of the presynaptic α2-adrenoceptors?
Responda
  • Salbutamol
  • Clonidini hydrochloridum
  • α-Methyldopum (Dopegyt)
  • Sotalol

Questão 18

Questão
Pharmacological effects of Clonidin are:
Responda
  • decreased peripheral vascular resistance
  • antihypertensive
  • inhibition of gastric secretion
  • antiarrhythmic

Questão 19

Questão
Adverse drug reactions of Clonidin are:
Responda
  • Dry mouth
  • Drowsiness and depression
  • Hypertensive attacks following abrupt cessation of treatment
  • CNS stimulation

Questão 20

Questão
For Methyldopa is true:
Responda
  • has antihypertensive effect
  • it is safe in pregnancy
  • could cause drug-induced parkinsonism
  • used to treat threatening abortion

Questão 21

Questão
Which of the following drugs are α1-adrenoblockers?
Responda
  • Prazosin
  • Doxazosin
  • Clonidin
  • Chlorpromazin

Questão 22

Questão
Pharmacological effects of Prazosin are:
Responda
  • dilation of the resistive and capacitive vessels
  • antihypertensive
  • relaxation of the muscles in the prostate and bladder neck
  • hyperglycaemia

Questão 23

Questão
Adverse drug reactions of α1-adrenoblockers are:
Responda
  • orthostatic collapse
  • hypokalemia
  • fluid retention
  • hypoglycaemia

Questão 24

Questão
Which of the following drugs are non-selective β-blockers?
Responda
  • Atenolol
  • Pindolol
  • Acebutolol
  • Propranolol

Questão 25

Questão
Which of the following drugs are selective β1-blockers?
Responda
  • Atenolol
  • Pindolol
  • Propranolol
  • Metoprolol

Questão 26

Questão
β-blockers are indicated in case of:
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  • hypertension
  • bronchial asthma
  • arrhythmia
  • ischaemic heart disease

Questão 27

Questão
Pharmacological effects of B-blockers are:
Responda
  • bronchodilation
  • negative inotropic effect
  • positive chronotropic effect
  • negative chronotropic effect

Questão 28

Questão
β-blocker approved for topical use in treatment of glaucoma is:
Responda
  • Bisoprolol
  • Metoprolol
  • Timolol
  • Propranolol

Questão 29

Questão
When applied topically in the eye the B-blocker Timolol will:
Responda
  • increase the intraocular pressure
  • decrease the intraocular pressure
  • cause miosis
  • cause mydriasis

Questão 30

Questão
Potential adverse drug reactions of β-blockers are.
Responda
  • hypoglycaemia
  • bronchoconstriction
  • hyperglycaemia
  • nightmares

Questão 31

Questão
For long-term treatment with β-blockers is true:
Responda
  • up-regulation of B-adrenergic receptors
  • down-regulation of B-adrenergic receptors
  • the therapy should be ceased abruptly
  • the therapy should not be ceased abruptly

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