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Hematology Diagnostics

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Quiz sobre Hematology Diagnostics, criado por lwashing13 em 09-11-2014.
lwashing13
Quiz por lwashing13, atualizado more than 1 year ago
lwashing13
Criado por lwashing13 aproximadamente 11 anos atrás
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Resumo de Recurso

Questão 1

Questão
All of the following would decrease WBC levels EXCEPT
Responda
  • trauma
  • immunosuppression
  • drug toxicity
  • overwhelming infection

Questão 2

Questão
WBC in child < 2
Responda
  • 6,200-17,000
  • 5,000-10,000
  • 9,000-30,000

Questão 3

Questão
WBC level in >2 to adult
Responda
  • 5,000-10,000
  • 6,200-17,000
  • 9,000-30,000

Questão 4

Questão
WBC in newborn
Responda
  • 5,000-10,000
  • 6,200-17,000
  • 9,000-30,000

Questão 5

Questão
What are the panic values for WBC
Responda
  • < 1,000 > 30,000
  • < 2,000 > 30,000
  • < 2,500 > 30,000

Questão 6

Questão
All of the following are granulocytes EXCEPT
Responda
  • monocytes
  • neutrophils
  • basophils
  • eosinophils

Questão 7

Questão
T and B cells are part of what type of agranulocyte?
Responda
  • lymphocyte
  • monocyte
  • eosinophil

Questão 8

Questão
How many days are neutrophils in circulation?
Responda
  • 4
  • 5
  • 6
  • 7

Questão 9

Questão
Critical value of actual neutrophil count (ANC)
Responda
  • < 1200
  • < 1000
  • < 800

Questão 10

Questão
Eosinophils are what % of WBC's
Responda
  • 55-70
  • 1-4
  • -.5-1

Questão 11

Questão
Eosinophils and basophils respond to viral and bacterial infections.
Responda
  • True
  • False

Questão 12

Questão
Eosinophils and Basophils respond in allergic reactions and parasitic infections
Responda
  • True
  • False

Questão 13

Questão
What is responsible for hives and skin reactions due to cytoplasm containing heparin, histamine, and serotonin?
Responda
  • neutrophil
  • eosinophil
  • basophil

Questão 14

Questão
What type of cells provide humoral immunity?
Responda
  • T cells
  • B cells

Questão 15

Questão
What type of cell produces interferon?
Responda
  • lymphocyte
  • monocyte
  • neutrophil
  • eosinophil

Questão 16

Questão
All of the following are true for hemoglobin EXCEPT
Responda
  • Transports Oxygen
  • Transports Carbon Dioxide
  • acts as an acid base buffer
  • indicates infection

Questão 17

Questão
Hemoglobin panic values:
Responda
  • < 10 > 30
  • < 5 > 20
  • < 8 > 15

Questão 18

Questão
Hematocrit critical value:
Responda
  • < 20 > 60
  • < 15 > 45
  • < 10 > 60

Questão 19

Questão
MCV
Responda
  • % of hemoglobin in a single RBC (color)
  • Average weight of hemoglobin within a RBC
  • Average volume/size of single RBC

Questão 20

Questão
Increased reticulocyte means all of the following EXCEPT
Responda
  • bone marrow is putting an increased amount of RBC's into bloodstream
  • hemolytic anemia
  • aplastic anemia
  • SSA

Questão 21

Questão
Normal or low reticulocyte count with anemia indicates all of the following EXCEPT
Responda
  • hemolysis
  • Marrow is not appropriately responding
  • aplastic
  • Fe deficiency
  • B12 deficiency

Questão 22

Questão
All would be included in the work-up for macrocytic anemia EXCEPT?
Responda
  • B12 and folate
  • iron studies
  • peripheral smear
  • TSH

Questão 23

Questão
All would be included in microcytic anemia work-up EXCEPT
Responda
  • iron studies
  • peripheral smear
  • Hgb electrophoresis
  • bone marrow biopsy
  • B12 and folate

Questão 24

Questão
Iron tells us:
Responda
  • all proteins available for binding to iron
  • the major iron-storage protein
  • quantity of iron bound to transferrin

Questão 25

Questão
TIBC tells us:
Responda
  • the major iron storage protein
  • quantity of iron bound to transferrin
  • all proteins available for binding to iron

Questão 26

Questão
What are the iron-binding proteins?
Responda
  • transferrin
  • ferritin

Questão 27

Questão
What is the major iron-storage protein?
Responda
  • Transferrin
  • Ferritin

Questão 28

Questão
What is needed for adequate functioning of the RBC's and WBC's due to synthesis of amino acids and DNA?
Responda
  • ferritin
  • folic acid
  • transferrin

Questão 29

Questão
What does B12 activate?
Responda
  • folate
  • transferrin
  • ferritin

Questão 30

Questão
The Schilling Test is used for all of the following EXCEPT:
Responda
  • iron deficiency anemia
  • pernicious anemia
  • determine the cause of B12 deficiency

Questão 31

Questão
Increases LDH, increased bilirubin, and decreased haptoglobin are indicative of:
Responda
  • acute blood loss
  • hemolysis

Questão 32

Questão
Fetal hemoglobin contains all of the following EXCEPT:
Responda
  • 2 alpha chains
  • 2 beta chains
  • 2 gamma chains

Questão 33

Questão
What is the most common type of hemoglobin in adults?
Responda
  • A
  • A2
  • F

Questão 34

Questão
All of the following are found in sickle cell disease except?
Responda
  • D
  • S
  • C

Questão 35

Questão
What type of hemoglobin doesn't carry oxygen well?
Responda
  • S
  • A
  • F
  • C

Questão 36

Questão
What type of hemoglobin is found in people of Southeast Asian descent?
Responda
  • C
  • E
  • D

Questão 37

Questão
HBSS indicates:
Responda
  • inherited 1 sickle cell gene and 1 abnormal hemoglobin gene
  • inherited 2 sickle cell genes
  • inherited 1 sickle cell gene and 1 normal hemoglobin gene

Questão 38

Questão
HBSC indicates
Responda
  • one sickle cell gene and one abnormal hemoglobin gene
  • 1 sickle cell gene and one normal hemoglobin gene
  • 2 sickle cell genes

Questão 39

Questão
What test is used to differentiate hemolytic anemia into hereditary spherocytosis or thalassemia?
Responda
  • hemoglobin electrophoresis
  • genetic testing
  • osmotic fragility test

Questão 40

Questão
Decreased osmotic fragility test indicates:
Responda
  • hereditary spherocytosis
  • thalassemia
  • autoimmune hemolytic anemias

Questão 41

Questão
What should be suspected in people with hemolysis reactions after certain medications and foods?
Responda
  • G6PD deficiency
  • pernicious anemia
  • hereditary spherocytosis

Questão 42

Questão
PTT
Responda
  • intrinsic
  • extrinsic

Questão 43

Questão
All of the following cause prolonged bleeding time EXCEPT
Responda
  • iron deficiency
  • ASA/NSAIDs
  • Von Willebrand
  • scurvy
  • renal failure

Questão 44

Questão
What is used to monitor heparin therapy
Responda
  • aPTT
  • bleeding time
  • platelet count

Questão 45

Questão
aPTT/PTT evaluate what pathways?
Responda
  • extrinsic and common coagulation pathways
  • intrinsic and common coagulation pathways
  • intrinsic and extrinsic pathways

Questão 46

Questão
Warfarin therapy and liver synthetic function is monitored using:
Responda
  • PT/INR
  • aPTT/PTT

Questão 47

Questão
PT/INR evaluates what pathways?
Responda
  • intrinsic and common
  • extrinsic and common
  • intrinsic and extrinsic

Questão 48

Questão
Fibrinogen is a measure of what pathway?
Responda
  • intrinsic and common
  • extrinsic and common
  • factor I and common

Questão 49

Questão
A decrease in antithrombin III leads to
Responda
  • increased bleeding
  • hypercoagulation

Questão 50

Questão
Protein C inhibits:
Responda
  • Va and VIIIa
  • II, X, XI, XII
  • V, VI, VII

Questão 51

Questão
Antithrombin III inhibits:
Responda
  • Va, VIIIa
  • II, X, XI, XII
  • V, VI, VII

Questão 52

Questão
What is the co-factor to Protein C
Responda
  • Protein S
  • antithrombin III
  • factor Va

Questão 53

Questão
Proteins C and S are decreased in all of the following EXCEPT
Responda
  • Coumadin
  • liver disease
  • renal disease
  • nutritional deficiency

Questão 54

Questão
C4 binding protein from autoimmune diseases can inactivate:
Responda
  • protein S
  • antithrombin III
  • factor Va

Questão 55

Questão
What is the most common hereditary coagulation disorder in the US?
Responda
  • Factor V-Leiden
  • sickle cell disease
  • hereditary spherocytosis

Questão 56

Questão
In Factor V-Leiden, protein C can't break it down which results in all of the following EXCEPT
Responda
  • increased thrombin generation
  • increased antithrombin III generation
  • mild hypercoaguable state

Questão 57

Questão
APC is a natural anticoagulant that inactivates
Responda
  • X, XII, XI
  • fVa and fVIIIa
  • V, VI, VII

Questão 58

Questão
patients with factor V leiden will be resistant to WHAT when exposed to APC
Responda
  • deactivation of fVa and fVIIIa
  • activation of fVa and fVIIIa

Questão 59

Questão
In what disorder is the clotting mechanism inappropriately triggered producing thrombosis and hemorrhage?
Responda
  • Factor V Leidein
  • DIC
  • APC

Questão 60

Questão
In DIC, fibrin clots form intravascularly consuming platelets and clotting factors leading to what?
Responda
  • decreased bleeding time
  • increased clotting
  • excessive bleeding

Questão 61

Questão
The following image shows:
Image:
sideroblastic.jpeg (image/png)
Responda
  • sickle cell
  • iron deficiency
  • sideroblastic

Questão 62

Questão
What is the following smear depicting?
Image:
Heinz.jpeg (image/png)
Responda
  • Heinz bodies
  • nucleated RBC's
  • sideroblastic anemia

Questão 63

Questão
What acts as a carrier protein for factor VIII?
Responda
  • antithrombin III
  • Von Willebrand Factor
  • Hemophilia A

Questão 64

Questão
What is the most common bleeding disorder?
Responda
  • VWD
  • hemophilia A
  • hemophilia B

Questão 65

Questão
What is a Factor VIII deficiency?
Responda
  • Hemophilia A
  • Hemophilia B
  • Hemophilia C

Questão 66

Questão
What is a Factor IX deficiency?
Responda
  • Hemophilia A
  • Hemophilia B

Questão 67

Questão
Which hemophilia disorder is common among Ashkenazi Jews?
Responda
  • Hemophilia A
  • Hemophilia B
  • Hemophilia C

Questão 68

Questão
What would be high on your differential with mucosal and cutaneous bleeding?
Responda
  • VWD
  • hemophilia

Questão 69

Questão
What would be high on your differential with bleeding in joints, muscle, and GI tract?
Responda
  • VWD
  • hemophilia

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