Molecular Biology MCQs

Descrição

Quiz sobre Molecular Biology MCQs, criado por Hussain Basheer em 07-06-2019.
Hussain Basheer
Quiz por Hussain Basheer, atualizado more than 1 year ago
Hussain Basheer
Criado por Hussain Basheer aproximadamente 5 anos atrás
78
1

Resumo de Recurso

Questão 1

Questão
Which processes are parts of mRNA maturation?
Responda
  • splicing
  • 3´ capping
  • formation of double-stranded regions
  • polyadenylation

Questão 2

Questão
Down syndrome is caused by
Responda
  • a gene mutation
  • a structural chromosomal mutation
  • a numerical chromosomal mutation
  • a frameshift mutation

Questão 3

Questão
During anaphase II of meiosis
Responda
  • homologues separate and migrate towards opposite
  • sister chromatids separate and migrate towards opposite poles
  • nuclear membrane reforms
  • chromosomes line up in a single line

Questão 4

Questão
What is a promoter
Responda
  • it is a protein complex
  • it is a nucleotide sequence
  • it is needed for initiation of replication
  • it is crucial for transcription initiation

Questão 5

Questão
A primer is a short sequence of
Responda
  • RNA where replication starts
  • DNA where transcription starts
  • DNA where replication starts
  • RNA where translation startS

Questão 6

Questão
A primer is a short
Responda
  • protein sequence where replication starts
  • DNA sequence where transcription starts
  • RNA sequence where replication starts
  • RNA sequence where translation starts

Questão 7

Questão
DNA replication is
Responda
  • conservative
  • semiconservative
  • dispersive
  • continuous

Questão 8

Questão
Necrosis is
Responda
  • a result of acute chronic damage
  • controlled genetically
  • characterized by inflammation
  • characterized by rupture of the plasma membrane

Questão 9

Questão
The nucleosome
Responda
  • is DNA wrapped around a histone octamer
  • contains four types of histone proteins
  • is a complex of DNA and non-histone proteins;
  • contains five types of histone proteins

Questão 10

Questão
RNA Polymerase III transcribes:
Responda
  • mRNA;
  • 5.8S rRNA
  • tRNA
  • 5S rRNA

Questão 11

Questão
Synapsis occurs during
Responda
  • mitosis
  • anaphase I
  • prophase I
  • mitosis and meiosis

Questão 12

Questão
Which statements for oogenesis are true?
Responda
  • it is interrupted process
  • meiosis II is accomplished after fertilization
  • starts during puberty
  • has 4 distinct stages

Questão 13

Questão
Oogenesis begins
Responda
  • in the embryonic period
  • at birth
  • at puberty
  • in the last week of gestation

Questão 14

Questão
In oogenesis meiosis II is accomplished
Responda
  • at birth
  • after fertilization
  • before fertilization
  • at ovulation

Questão 15

Questão
A missense mutation
Responda
  • is an exchange of a coding codon with a STOP codon
  • is an exchange of a coding codon with a codon coding for another amino acid
  • a coding codon with a codon coding for the same aminoacid
  • changes the amino acid sequence of the protein

Questão 16

Questão
tRNA carries
Responda
  • The amino acid to the nucleuS
  • the rRNA to the mRNA
  • the mRNA to the nucleus
  • the amino acid to the ribosome

Questão 17

Questão
snRNA are localized in the
Responda
  • nucleus
  • cytoplasm
  • mitochondria
  • cell membrane

Questão 18

Questão
snRNA is used in
Responda
  • translation
  • splicing
  • polyadenylation
  • transcription

Questão 19

Questão
Helicase
Responda
  • separates the two DNA strands
  • elongates the newly synthesized strand
  • joins the Okazaki fragments
  • removes the supercoiling

Questão 20

Questão
Necrosis is characterized by
Responda
  • shrinkage of the cell
  • DNA ladder
  • rupture of the cell membrane
  • genetic program

Questão 21

Questão
In eukaryotes the first amino acid synthesized during translation is
Responda
  • isoleucine
  • leucine
  • methionine
  • formylmethionine

Questão 22

Questão
Western blotting is a method for detection of:
Responda
  • RNA
  • DNA
  • proteins
  • lipids

Questão 23

Questão
Southern blotting is a method for detection of:
Responda
  • RNA
  • DNA
  • sugars
  • proteins

Questão 24

Questão
Northern blotting is a method for detection of
Responda
  • RNA
  • DNA
  • proteins
  • lipids

Questão 25

Questão
The nitrogen bases in the DNA helix are linked by
Responda
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Questão 26

Questão
In metaphase of mitosis
Responda
  • the nucleolus breaks down
  • chromosomes are at the equator
  • the nuclear membrane reforms
  • chromosomes move to the opposite poles

Questão 27

Questão
Pyrimidines are
Responda
  • adenine and guanine
  • adenine and cytosine
  • thymine and guanine
  • thymine and cytosine

Questão 28

Questão
Purines are
Responda
  • adenine and thymine
  • thymine and guanine
  • adenine and guanine
  • thymine and cytosine

Questão 29

Questão
Mitochondrial DNA is
Responda
  • linear
  • single-stranded
  • inherited paternally
  • circular

Questão 30

Questão
If the mRNA has 90 codons, then the polypeptide chain is made of
Responda
  • 270 amino acids
  • 30 aminoacids
  • 90 amino acids
  • 60 amino acids

Questão 31

Questão
. mRNA
Responda
  • carries the amino acid to the ribosome
  • is synthesized in the cytoplasm
  • is the template for translation
  • contains rRNA genes

Questão 32

Questão
The acrosomal reaction
Responda
  • enables the entry of the sperm cell into oocyte
  • enables fusion of the male and female pronuclei
  • prevents polyspermy
  • completes meiosis II of the oocyte

Questão 33

Questão
The cortical reaction
Responda
  • enables the entry of the sperm cell into the oocyte
  • enables the fusion of the male and female pronuclei
  • prevents polyspermy
  • changes the membrane potential of the sperm cell membrane

Questão 34

Questão
Crossing-over occurs during
Responda
  • anaphase I
  • prophase I
  • mitosis
  • metaphase

Questão 35

Questão
Okazaki fragments form in the process of:
Responda
  • transcription
  • translation
  • splicing
  • replication

Questão 36

Questão
. A missense mutation changes the
Responda
  • amino acid sequence of the protein
  • open reading frame of the gene
  • order of codons within the gene
  • position of the TATA box in the promoteR

Questão 37

Questão
PCR is a method for amplification of
Responda
  • RNA
  • DNA
  • sugars
  • proteins

Questão 38

Questão
47 XX+21 is the genetic formula of a female with
Responda
  • Turner syndrome
  • Down syndrome
  • Kleinfelter syndrome
  • Edwards syndrome

Questão 39

Questão
A male with a karyotype 47, XXY has
Responda
  • Turner syndrome
  • Kleinfelter syndrome;
  • Down syndrome
  • Edwards syndrome

Questão 40

Questão
A female with a karyotype 45, X0 has
Responda
  • Turner syndrome
  • Kleinfelter syndrome
  • Down syndrome
  • Edwards syndrome

Questão 41

Questão
The genetic formula 45, XO is typical of
Responda
  • Down syndrome
  • Kleinfelter syndrome
  • Turner syndrome
  • Edwards syndrome

Questão 42

Questão
Turner syndrome is
Responda
  • trisomy of the X chromosome
  • monosomy of the X chromosome
  • monosomy of the Y chromosome
  • trisomy of the Y chromosome

Questão 43

Questão
Edwards syndrome is a trisomy of chromosome
Responda
  • 12
  • 21
  • 23
  • 18

Questão 44

Questão
In proteins amino acids are linked by
Responda
  • peptide bonds
  • disulfide bridges
  • hydrogen bonds
  • triphosphate bridges

Questão 45

Questão
In anaphase of mitosis
Responda
  • The nucleolus breaks down
  • chromosomes are at the equator
  • the nuclear membrane reforms
  • chromosomes move to the opposite poles

Questão 46

Questão
In meiosis sister chromatids separate during
Responda
  • metaphase I
  • telophase II
  • anaphase II
  • prometaphase I

Questão 47

Questão
An enhancer is a
Responda
  • nucleotide sequence
  • protein complex
  • transcription factor
  • ribozyme

Questão 48

Questão
In DNA nucleotides are linked by
Responda
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Questão 49

Questão
The functions of miRNAs are
Responda
  • coding
  • enzymatic
  • transporting
  • regulatory

Questão 50

Questão
The nitrogen bases in the DNA helix are linked by
Responda
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Questão 51

Questão
The 5’ cap is important for
Responda
  • snRNA stability
  • formation of the spliceosome
  • termination of transcription
  • mRNA transport into the cytoplasm

Questão 52

Questão
The TATA sequence is commonly found in:
Responda
  • telomeres
  • centromeres
  • promoters
  • enhancers

Questão 53

Questão
In meiosis sister chromatids separate during
Responda
  • metaphase I
  • telophase II
  • anaphase II;
  • prometaphase I

Questão 54

Questão
The Robertsonian translocation is a
Responda
  • structural chromosomal mutation
  • gene mutation
  • point mutation
  • separation of metacentric chromosomes.

Questão 55

Questão
Which proteins control the cell cycle?
Responda
  • snRNPs
  • activators
  • CDKs
  • promoters

Questão 56

Questão
Polyadenylation occurs at
Responda
  • the 5’ end of DNA during replication
  • the 3’ end of rRNA during transcription
  • the 5’ end of mRNA during transcription
  • the 3’ end of mRNA during transcription

Questão 57

Questão
The spliceosome contains
Responda
  • transcription factors
  • endonucleases
  • snRNPs
  • enhancers

Questão 58

Questão
Capacitation is a reaction that occurs in
Responda
  • oogenesis
  • spermatogenesis
  • fertilization
  • meiosis

Questão 59

Questão
The START codon for translation is
Responda
  • AAU
  • AUU
  • AUG
  • AUC

Questão 60

Questão
How many types of rRNA exist in eukaryotes?
Responda
  • 1
  • 2
  • 3
  • 4

Questão 61

Questão
DNA replication takes place during
Responda
  • S phase
  • G1 phase
  • metaphase
  • telophase

Questão 62

Questão
Prokaryotic mRNA
Responda
  • is monocistronic
  • contains introns;
  • has a 5’ cap
  • has more than one cistron

Questão 63

Questão
Heterochromatin
Responda
  • contains functional genes
  • is decondensed
  • replicates late in the S phase
  • is lightly stained

Questão 64

Questão
Euchromatin
Responda
  • is darkly stained
  • is replicated late in the S phase
  • contains functional genes
  • is highly condensed

Questão 65

Questão
Apoptosis
Responda
  • causes inflammation
  • is under genetic control
  • is caused by rupture of the cell membrane
  • causes enlargement of the cell

Questão 66

Questão
Which enzymes promote apoptosis?
Responda
  • snRNPs
  • topoisomerases
  • polymerases
  • caspases

Questão 67

Questão
Intron is the
Responda
  • coding region of a gene
  • non-coding region of a gene
  • 2 nucleotides that code for one amino acid
  • 3 nucleotides that code for one amino acid

Questão 68

Questão
Exon is the:
Responda
  • coding region of a gene
  • non-coding region of a gene
  • 2 nucleotides that code for one amino acid
  • 3 nucleotides that code for one amino acid

Questão 69

Questão
Spermatogenesis
Responda
  • is an interrupted process
  • begins at birth
  • has 4 distinct stages
  • is very inefficient

Questão 70

Questão
The consequence of a nonsense mutation is
Responda
  • change in the amino acid sequence
  • truncated protein
  • shift of the open reading frame
  • different codon order

Questão 71

Questão
The first AUG sequence in eukaryotes is located in the
Responda
  • Shine-Dalgarno sequence
  • Kozak sequence
  • Pribnow box
  • TATA box

Questão 72

Questão
Kozak sequence
Responda
  • tRNA
  • mRNA
  • rRNA
  • snRNA

Questão 73

Questão
Which method is used for DNA amplification?
Responda
  • Southern blot
  • Northern blot
  • PCR
  • RT-PCR

Questão 74

Questão
Which enzyme is not involved in DNA replication?
Responda
  • RNA polymerase
  • ligase
  • RNA primase
  • telomerase

Questão 75

Questão
The acrosome is:
Responda
  • an organelle at the tip of the sperm cell
  • the site where the flagellum of the sperm cell begins
  • an organelle in the perivitelline space of the oocyte
  • the vitelline envelope of the sperm cell

Questão 76

Questão
The polypeptide chain is built up of
Responda
  • fatty acids
  • amino acids
  • disaccharides
  • polysaccharides

Questão 77

Questão
In oogenesis meiosis II is accomplished
Responda
  • at birth
  • after fertilization
  • before fertilization
  • at ovulation

Questão 78

Questão
The nucleosome
Responda
  • Contains H2A, H2B, H3, H4 histone molecules;
  • contains 2 types of histone molecules
  • is DNA wrapped around a non-histone octamer
  • contains 6 types of histone molecules

Questão 79

Questão
The ribosome is a complex of
Responda
  • DNA and proteins
  • mRNA and tRNA
  • rRNA and polysaccharides
  • rRNA and proteins

Questão 80

Questão
Restriction enzymes are used in
Responda
  • DNA replication
  • DNA cloning
  • RNA replication
  • RNA restriction

Questão 81

Questão
Which nucleic acid functions as a ribozyme?
Responda
  • mRNA
  • DNA
  • rRNA
  • ssDNA

Questão 82

Questão
Plasmids are circular DNAs in
Responda
  • mammalian cells
  • viruses
  • bacterial cells
  • sperm cells

Questão 83

Questão
. The nucleosome contains
Responda
  • an octamer of histones and 246 bp of DNA
  • an octamer of histones and 146 bp of DNA
  • a hexamer of histones and 146 bp of DNA
  • a hexamer of histones and 146 bp of RNA

Questão 84

Questão
SSB proteins are required for
Responda
  • transcription
  • translation
  • splicing
  • replication

Questão 85

Questão
Which enzyme does not take part in DNA replication?
Responda
  • helicase
  • ligase
  • RNA primase
  • RNA polymerase

Questão 86

Questão
Which enzyme unwinds DNA?
Responda
  • DNA-polymerase
  • helicase
  • transferase
  • topoisomerase

Questão 87

Questão
What is the sequence of the mRNA, if the DNA antisense strand is AATCCGGAT?
Responda
  • 5’ ATCCGGATT 3’
  • 5’ TTAGGCCTA 3’
  • 5’ AUCCGGAUU 3’
  • 5’ UUAGGCCUA 3’

Questão 88

Questão
Topoisomerase
Responda
  • removes supercoiling of DNA
  • separates the two DNA strands
  • destroys the nuclear envelope
  • forms the peptide bond

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