Questão 1
Questão
inspiration occurs as a result of
Responda
-
an upward movement of the diaphragm
-
movement of the ribs closer together due to the contraction of the inspiratory intercostal muscles
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downward movement of the diaphragm
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a and b
-
b and c
Questão 2
Questão
in order for the lungs to function normally, the intrapleural pressure must
Responda
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be lower than alveolar pressure
-
be between +5 and +10mmHg above the atmospheric pressure
-
alternate between being less than and greater than the atmospheric pressure
-
change as respiratory demands of the body change
-
be the same as the atmospheric pressure
Questão 3
Questão
most of the CO2 that is transported in blood is
Responda
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dissolved in the plasma
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bound to haemoglobin
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in carbonic acid
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in bicarbonate ions
-
in carbonic anhydrase
Questão 4
Questão
in which vesicular bed does hypoxia cause vasconstriction
Responda
-
coronary
-
pulmonary
-
cerebral
-
muscle
-
skin
Questão 5
Questão
which of the following is the site of the highest airway resisitance
Responda
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mouth
-
largest bronchi
-
medium sized bronchi
-
smallest bronchi
-
alveoli
Questão 6
Questão
compared with the systemic circulation, the pulmonary circulation has a:
Questão 7
Questão
hypoventilation will cause
Responda
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hypercapnia
-
anoxia
-
hypoxia
-
hypocapnia
-
a and c
Questão 8
Questão
which of the following events is caused by an increased pCO2 in tissues
Questão 9
Questão
vital capacity include
Questão 10
Questão
which muscles contract in quiet breathing
Questão 11
Questão
which of the following events are sympathetic effects
Responda
-
vasoconstriction in the lungs
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dilation of the bronchi
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vasodilation in the lungs
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constriction of the bronchi
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a and b
Questão 12
Questão
which of the following is related to the respiratory function of the lungs
Questão 13
Questão
which factors affect the gas diffusion through the respiratory membrane
Responda
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membrane thickness
-
membrane area
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tidal volume
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diffusion quotient
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a and b
Questão 14
Questão
gas exchange in the respiratory system of humans takes place in the
Responda
-
trachea
-
bronchus
-
bronchioles
-
alveoli
-
larynx
Questão 15
Questão
as regards the distribution of ventilation (V) and perfusion (Q), the V/Q ratio
Responda
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gradient of change of ventilation is greater than that of perfusion
-
ventilation increases up the lung
-
perfusion increases up the lung
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at apex is greater than at base in prone position
-
none of the above
Questão 16
Responda
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is produced by type I alveolar cells
-
acts like detergent in water
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reduces the amount of negative intrapleural pressure
-
reduces blood flow to the lungs
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increases pulmonary compliance
Questão 17
Questão
carbon dioxide transport is
Questão 18
Questão
obligatory respiratory muscles are
Responda
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the diaphragm and mm. intercostales interni
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the diaphragm and mm. intercostales externi
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mm.abdominales
-
mm. serrati posteriores inferiores
-
all of the above
Questão 19
Questão
the bronchial muscles relax under the influence of
Questão 20
Questão
for the surfactant it is true that
Responda
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is produced by type II alveolar cells
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consists of phospholipids, proteins and carbohydrates
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decreases the alveolar surface tension at the end of expiration
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protects the lungs from atelectasis and edema
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all of the above
Questão 21
Questão
for the alveolar capillary membrane it is true that
Responda
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consists of alveolar epithelium, pulmonary capillary endothelium and their base membranes with very thin interstitial space between them
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diffusion of O2 and CO2 occurs across it
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has better permeability for O2 than CO2
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a and b
-
none of the above
Questão 22
Questão
dilation of bronchi can be achieved by
Responda
-
increased level of catecholamines
-
decreased level of catecholamines
-
increase of acetylcholine and serotonin levels
-
increase of bradikinine and histamine levels
-
a,c, and d
Questão 23
Questão
normal breathing at rest is called
Responda
-
polypnoe
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eupnoe
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tachypnoe
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dyspnoe
-
hyperpnoe
Questão 24
Questão
during expiration
Responda
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the thoracic cage recoils and the diaphragm moves upwards
-
the intrapleural pressure decreases
-
the intrapleural pressure increases
-
a and b
-
a and c
Questão 25
Questão
the sympathetic division of ANS affects the bronchial muscles activating
Questão 26
Questão
tidal volume (TV) is
Responda
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the volume of air, which passes through the lungs per minute
-
bigger than the residual volume (RV)
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an element of the functional residual capacity (FRC)
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a, b and c
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0.5 1 approximately
Questão 27
Questão
the intrapleural pressure is
Responda
-
higher than the atmospheric pressure
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lower than the atmospheric pressure
-
equal to the atmospheric pressure
-
depends on the water molecules surface tension and elastic fibers
-
b and d
Questão 28
Questão
the anatomical dead space
Questão 29
Questão
the residual volume (RV) is
Responda
-
the volume of air, which remains in the lungs after maximal expiration
-
the volume of air, which remains in the lungs after maximal inspiration
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is about 2-3l
-
is the tidal volume plus the inspiratory reserve volume
-
a component of the vital capacity (VC)
Questão 30
Questão
which of the following factors shifts the dissociation curve of HbO2 to the right
Responda
-
increased pCO2
-
decreased pCO2
-
decreased pO2
-
increased pO2
-
increased pH
Questão 31
Questão
it is not true that vital capacity (VC)
Responda
-
is a sum of ERV + TV + IRV
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depends on sex and age
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depends on chest measurement
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is a sum of IC + ERV
-
is a sum of TV + ERV + RV
Questão 32
Questão
there are smooth muscles in the respiratory system
Responda
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on the external surface of the lungs
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on the medial surface of the lungs
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in the trachea, bronchi and bronchioles
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around the alveoli
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on the external and medial surfaces of the lungs
Questão 33
Questão
it is true that the air in the alveoli
Responda
-
has a higher CO2 content than the atmosphere
-
has lower O2 content than in the atmosphere
-
consists of N2 approximately equal to that in the atmosphere
-
has the same components as the atmosphere
-
a, b and c
Questão 34
Questão
the elastic fibers in the lungs are situated
Questão 35
Questão
the peripheral chemoreceptors are situated
Responda
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on the ventral surface of medulla oblongata
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on the dorsal surface of medulla oblongata
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in arcus aortae and arteria carotis communis
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in the inferior and superior vena cavae and the right atrium
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in the hypothalamus
Questão 36
Questão
which of the following compounds doesnt take part in the transport of CO2 under physiological conditions
Questão 37
Questão
which of the following factors increases the rate of breathing
Questão 38
Questão
the ventilation/ perfusion (V/Q) ratio of 0.8 refers to
Responda
-
the upper parts of the lungs in upright position
-
the middle parts of the lungs in upright position
-
the lower parts of the lungs in upright position
-
in all parts of the lungs in supine position
-
b and d
Questão 39
Questão
which of the following does not happen during inspiration
Responda
-
the ribs move upward
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the diaphragm lifts up
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the anterior-posterior dimensions of the chest are increased
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the transverse dimensions of the thorax are increased
-
the scalene and sternocleidomastoid muscles can be recruited for inspiration
Questão 40
Questão
total lung capacity (TLC) of men would normally be about
Responda
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4200ml
-
1500ml
-
6000ml
-
8000ml
-
10000ml
Questão 41
Questão
oxygen enters the cell via
Responda
-
diffusion
-
filtration
-
osmosis
-
active transport
-
passive transport
Questão 42
Questão
most of the carbon dioxide produced by tissues is transported to the lungs as
Responda
-
small gas bubbles in the plasma
-
gas bound to hemoglobin in the red blood cells
-
bicarbonates in the plasma
-
gas bound to white blood cells and albumin
-
gas transported through the lymphatic system
Questão 43
Questão
the need to breathe is caused by
Questão 44
Questão
where does gas exchange take place
Responda
-
bronchioles
-
bronchi
-
pulmonary capillaries
-
roots of the lungs
-
trachea
Questão 45
Responda
-
makes expiration difficult
-
reduces the surface tension of the water layer within alveoli
-
relaxes the bronchi
-
increases in concentration when the sympathetic tone is increased
-
in increased concentration causes oedema
Questão 46
Questão
hemoglobin gives up oxygen when the environment is more
Responda
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acidic
-
alkaline
-
icy
-
open
-
none of the above
Questão 47
Questão
acidosis is when blood pH is below
Questão 48
Questão
the bronchodilatory effect of atropin is due to blocking
Questão 49
Questão
the carotid bodies
Responda
-
are stretch receptors in the walls of the internal carotid arteries
-
have a blood flow per unit volume similar to that in the brain
-
are influenced by the blood temperature
-
generate less afferent impulses when blood H+ concentration rises
-
and the aortic bodies are mainly responsible for the increased ventilation in hypoxia
Questão 50
Questão
pulmonary surfactant increases
Responda
-
the surface tension of the fluid lining alveolar walls
-
lung complaince
-
in effectiveness as the lungs are inflated
-
in amount when pulmonary blood flow is interrupted
-
the airflow resistance in bronchi
Questão 51
Questão
the hemoreceptors in the carotid artery and aortic arc are excited when
Responda
-
pCO2 in plasma is decreased
-
plasma pH is increased
-
pO2 in plasma is increased
-
pO2 in plasma is decreased
-
tO is increased
Questão 52
Questão
during inspiration
Responda
-
intrapleural pressure is lowest at mid-inspiration
-
intrapulmonary pressure is lowest around mid-inspiration
-
intraoesophageal pressure is lowest at mid-inspiration
-
the rate of air flow is greatest at end-inspiration
-
the lung volume/intrapleural pressure relationship is the same as in expiration
Questão 53
Questão
the bronchial muscles relax under the influence of
Questão 54
Responda
-
the rate of alveolar ventilation at rest exceeds the rate of alveolar capillary perfusion
-
the ventilation/ perfusion (V/Q) ratio in less 0.6 during maximal exercise
-
the V/Q ratio is higher at the apex than at the base of the lungs when a person is standing
-
oxygen transfer can be explained by active transport
-
dead space decreases during inspiration
Questão 55
Questão
bronchial smooth muscle contracts in response to
Responda
-
bronchial mucosal irritation
-
local beta adrenoceptor stimulation
-
a fall in bronchial pO2
-
inhalation of air warmed to 37C
-
circulating noradrenaline
Questão 56
Questão
which of the following factors stimulate respiration
Responda
-
decrease pCO2
-
increased pO2
-
alkalosis
-
decreased pCO2, increased pO2 alkalosis
-
increased pCO2, decreased pO2, alkalosis
Questão 57
Questão
CO2 is transported basically as
Questão 58
Questão
during inspiration
Responda
-
venous return to the heart is increased
-
less energy is expended than during expiration
-
lung expansion is assisted by surface tension forces in the alveoli
-
lung expansion begins when intrapleural pressure falls below atmospheric
-
the relative concentration of surfactant increases in alveoli
Questão 59
Questão
the residual volume (RV) is
Responda
-
the volume of air remaining in the lungs at the end of an expiration
-
greater on average in women than in men
-
3-4 liters on average in young adults
-
measured directly using a spirometer
-
smaller in old than in young people
Questão 60
Questão
a rise in arterial pCO2 causes
Responda
-
an increase in ventilation due to stimulation of peripheral and central chemoreceptors
-
a decrease in ventilation due to stimulation of central and peripheral chemoreceptors
-
a decrease in arterial pressure
-
a decrease in cerebral blood flow
-
a decrease in the plasma bicarbonate level
Questão 61
Questão
ventilation is increased during
Responda
-
periods when cerebrospinal fluid pH is reduced
-
compensated chronic renal failure
-
periods when plasma bicarbonate level is increased
-
deep sleep
-
exercise because of the ensuing fall in arterial pO2
Questão 62
Responda
-
arterial mean pressure is about one-sixth of systemic mean arterial pressure
-
blood flow/minute is greater then the systemic blood flow/minute
-
vascular resistance is about 50 per cent that of systemic vascular resistence
-
vascular capacity is similar to systemic vascular capacity
-
arterial pressure increases by about 50 per cent when cardiac output rises by 50 per cent
Questão 63
Questão
carbon dioxide is carried in the blood in
Responda
-
combination with the myoglobin molecule
-
combination with plasma globulins
-
physical solution in red blood cells
-
greater quantity in red blood cells than in plasma
-
greater quantity as HCO3- than as other forms
Questão 64
Questão
a shift of the oxygen dissociation curve of blood to the right
Responda
-
occurs in the pulmonary capillaries
-
occurs if blood temperature decreases
-
favours oxygen delivery to the tissues
-
favours oxygen uptake from the lungs by alveolar capillary blood
-
occurs if the pH of the blood increases
Questão 65
Questão
the compliance of the lungs and chest wall is
Responda
-
expressed as volume change per unit change in pressure
-
minimal during quiet breathing
-
increased by the surface tension of the fluid lining the alveoli
-
decreased by surfactant
-
changed by parallel displacement of the line relating lung volume to distending pressure
Questão 66
Questão
respiratory dead space
Responda
-
includes the volume of air in the airways up to the terminal bronchi
-
is where the gas exchange occur
-
is about 360ml
-
makes great changes in O2 and CO2 contain in alveolar air
-
includes the volume of air which reaches the alveoli
Questão 67
Questão
the correct statement is
Responda
-
the diffusion velocity of O2 and CO2 is equal
-
O2 diffuses 20 times faster than CO2
-
CO2 diffuses with 20 times higher velocity than CO2
-
the diffusion velocity of O2 is higher than that of CO2 when the concentration of O2 is increased
-
the diffusion velocity doesn't depend on cellular membrane permeability
Questão 68
Responda
-
the amount of O2 consumed after cessation of exercise
-
incurred because the pulmonary capillary walls limit O2 uptake during exercise
-
possible since skeletal muscle can function temporarily without oxygen
-
associated with a decrease in blood lactate
-
associated with metabolic alkalosis
Questão 69
Questão
the CO2 dissociation curve for whole blood shows that
Responda
-
its shape is sigmoid
-
blood saturates with CO2 when pCO2 exceeds normal alveolar levels
-
blood contains some CO2 even when the pCO2 is zero
-
oxygenation of the blood drives CO2 out of the blood
-
adding CO2 to the blood drives O2 out of the blood
Questão 70
Questão
bronchial asthma is likely to be relieved by
Responda
-
stimulation of cholinergic receptors
-
stimulation of beta adrenoreceptors
-
histamine aerosols
-
non steroidal anti-inflamatory drugs
-
mineralcorticoids
Questão 71
Questão
air in the pleural cavity (pneumothorax)
Responda
-
allows intrapleural pressure to rise and become equal to the atmospheric pressure
-
causes the underlying to collapse by compressing it
-
increases the functional residual capacity
-
leads to a slight inward movement of the chest wall
-
increases the vital capacity
Questão 72
Questão
loss of pulmonary elastic tissue in 'emphysema' reduces
Questão 73
Questão
complete obstruction of a major bronchus usually results in
Responda
-
collapse of the alveoli supplied by the bronchus
-
a rise in local intrapleural pressure
-
an increase in physiological dead space
-
an increase in blood flow to the lung tissue supplied by the bronchus
-
cyanosis
Questão 74
Questão
a shift of the oxygen dissociation curve of blood to the left
Responda
-
decreases the O2 content of blood at a given pO2
-
impairs O2 delivery to the tissues at the normal tissue pO2
-
occurs in blood perfusing hot extremities
-
occurs in blood with lower pH than with higher pH
-
is characteristic of adult blood when compared with fetal blood
Questão 75
Questão
a diver breathing air at depth of 30 metres under water
Responda
-
is exposed to a pressure equal to the surface
-
has a raised pressure of nitrogen in the alveoli
-
has a four fold increase in the oxygen content of blood
-
has a four fold increase in alveolar water vapour pressure
-
expends less energy than normal on the work of breathing
Questão 76
Responda
-
may be caused by high levels of carboxyhaemoglobin in the blood
-
may be caused by high levels of methaemoglobin in the blood
-
is seen in fingers of hands immersed in iced water
-
occurs more easily in anaemic than in polycythaemic patients
-
is severe in cyanide poisoning
Questão 77
Questão
histamine affects the bronchial muscles via
Questão 78
Responda
-
is reflexly initiated by irritation of the alveoli
-
is associated with relaxation of airways smooth muscles
-
depends on contraction of the diaphragm for expulsion of air
-
differs from sneezing in that the glottis is initially closed
-
is equivalent of sneezing
Questão 79
Questão
the sympathetic branch of the autonomic nervous system affects the bronchial muscles via
Questão 80
Questão
a 50% fall in the ventilation/perfusion (V/Q) ratio in each of lungs would
Responda
-
lower systemic arterial oxygen content
-
has no effect on the O2 in systemic circulation
-
increase the physiological dead space
-
lower systemic arterial carbon dioxide content
-
be compensated (with respect to oxygen uptake) by a high ratio in the other lung
Questão 81
Questão
the total amount of O2 carried by the circulation to the tissues/min. (oxygen delivery or total available oxygen)
Responda
-
normally equals the rate of O2 consumption by the body/min
-
is normally more than 95% combined with haemoglobin
-
must fall by about half if haemoglobin concentration is halved
-
is more closely related to PO2 than to percentage saturation of the blood with O2
-
must double if body oxygen consumption doubles
Questão 82
Questão
for air to enter the lungs during inspiration
Responda
-
the pressure inside the lungs must be higher than the atmospheric pressure
-
the pressure inside the lungs must become lower than the atmospheric pressure
-
the pressure inside the lungs must be equal to the atmospheric pressure
-
the diaphragm must be relaxed
-
the external intercostal muscles be relaxed
Questão 83
Questão
given: Co2 + H2O <-> H2CO3 <-> HCO3- + H+, what happens if bicarbonate ions are increased
Responda
-
more carbon monoxide produced
-
more bicarbonate ions produced
-
an increase in protons
-
there would be a shift to the left
-
there would be a shift to the right first, then to the left
Questão 84
Questão
the values (mmHg) for pCO2 and pO2 in the interstitial spaces of peripheral tissues are approximately
Responda
-
60;40
-
40;60
-
46;40
-
66;46
-
46;100
Questão 85
Questão
if forcefully exhaling as much air as possible after a normal breath, this is
Responda
-
tidal volume
-
expiratory reserve volume
-
maximum expiratory flow rate
-
eupnea
-
inspiratory reserve volume
Questão 86
Questão
which of the following reactions takes place in the systemic capillaries (where CO2 is higher and O2 is lower)?
Responda
-
Hb + O2 -> HbO2
-
Hb + CO2 -> HbCO2
-
HbCO2 -> Hb + CO2
-
H2CO3 -> HCO3- + H+
-
Na+ + HCO3- -> NaHCO3
Questão 87
Questão
water molecules on the surface of the alveoli generate surface tension. This force
Questão 88
Questão
what does the ventral respiratory group within the medulla oblongata do
Responda
-
triggers inspiration
-
decreased ventilation rate
-
nothing
-
triggers forced breathing
-
inhibits apneustic center, sets limit to over inflation of lungs
Questão 89
Questão
the region in the brain that sets the limit for over-inflation of lungs is located in the
Responda
-
pons
-
apneustic center
-
arterial blood chemistry
-
medulla oblongata
-
stretch receptors
Questão 90
Questão
in caissons disease pain in the joints and muscles is due to
Questão 91
Questão
normal value of FEV in an adult is
Questão 92
Questão
the most important gas maintaining alveolar ventilation is
Responda
-
oxygen
-
hydrogen
-
carbon dioxide
-
N2
-
CO
Questão 93
Questão
intrapleural pressure
Responda
-
is higher than the atmospheric pressure one as in inspiration
-
is lower than the atmospheric one as in inspiration
-
is equal to the atmospheric one
-
does not depend on the water molecules
-
does not change when pleural cavity hermeticity is inpaired
Questão 94
Questão
as one ascends to higher than 3000 meters above sea level changes in alveolar pO2 and pCO2 are as follows
Responda
-
decrease in pO2, increase in pCO2
-
decrease in pO2, decrease in pCO2
-
increase in both pO2 and pCO2
-
increase in pO2, decrease in pCO2
-
no change in pO2 and pCO2
Questão 95
Questão
surfactant is secreted by
Questão 96
Questão
which of the following effects is not observed during prolonged stay is space
Questão 97
Questão
airway resistance
Questão 98
Questão
decrease of pCO2 decrease in H+ and increased pO2 causes
Responda
-
hyperventilation
-
hypoventilation
-
hypercapnoea
-
hypoxia
-
none of the above
Questão 99
Questão
the intrapleural pressure at the end of deep inspiration is
Responda
-
-4mmHg
-
+4mmHg
-
-6mmHg
-
+6mmHg
-
-10mmHg
Questão 100
Questão
exercise which doubles the metabolic rate is likely to at least double the
Questão 101
Questão
sudden complete obstruction of the respiratory tract causes
Questão 102
Questão
the effects of moving from sea level to an altitude of 5000 metres include an increase in
Responda
-
alveolar ventilation
-
blood bicarbonate level
-
appetite for food
-
exercise tolerance
-
muscle strength
Questão 103
Questão
which of the following factors decrease the affinity of Hb to O2 in tissues
Responda
-
decreased pCO2
-
decreased pCO2 and lowered pH
-
lowered tO
-
increased pCO2 and lowered pH
-
decreased pCO2, higher pH and lowered tO
Questão 104
Questão
the bronchial muscles increase their tone under the influence of
Responda
-
adrenaline
-
noradrenaline
-
histamine
-
atropin
-
curare
Questão 105
Questão
the bronchial muscles dilate under the influence of
Responda
-
cateholamines
-
acetylcholine
-
histamine
-
bradikinine
-
serotonin
Questão 106
Questão
the pulmonary ventilation is a process that includes
Responda
-
only expiration
-
only inspiration
-
inspiration and expiration
-
exchange of O2 and CO2 via the capillary walls
-
transport of O2 and CO2 via blood
Questão 107
Questão
during inspiration
Responda
-
the water surface tension in alveoli decreases
-
the chest volume decreases and the diaphragm goes up
-
the tidal volume decreases
-
alveolar pressure increases
-
intrapleural pressure decreases
Questão 108
Questão
the exchange of O2 and CO2 between the capillary blood and the cells is carried out by
Responda
-
osmosis
-
diffusion
-
filtration
-
transport across pores
-
reabsorbtion