Questão 1
Questão
Where do endocrine cells secrete their hormones into?
Responda
-
Target cells
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Blood
-
Out of ducts
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Glands
Questão 2
Questão
What is a neuroendocrine cell?
Responda
-
A cell that released hormones into the blood upon depolarisation
-
A cell that releases neurotransmitter into the blood upon depolarisation
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A cell that releases hormones across the synaptic cleft upon depolarisation
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A cell that releases hormones onto neighbouring cells upon depolarisation
Questão 3
Questão
What type of chemical signalling occurs when a cell targets itself?
Responda
-
Autocrine
-
Paracrine
-
Endocrine
-
Neuroendocrine
Questão 4
Questão
What type of chemical signalling occurs when a cell targets a neighbouring cell?
Responda
-
Paracrine
-
Autocrine
-
Endocrine
-
Neuroendocrine
Questão 5
Questão
What type of signalling occurs when a cell releases a signal into the blood to be carried to its distant target cell?
Responda
-
Paracrine
-
Autocrine
-
Endocrine
-
Neuroendocrine
Questão 6
Questão
Which of the following hormones are secreted by neurosecretory cells?
Questão 7
Questão
Which of the following hormones are secreted by epithelial tissues?
Questão 8
Questão
What gives a hormone a long half-life?
Questão 9
Questão
The following questions will be about protein/peptide hormones. What must happen to preprohormones to form active prohormones?
Questão 10
Questão
How are active protein/peptide hormones released?
Questão 11
Questão
Are protein/peptide hormones protein-bound in circulation?
Questão 12
Questão
Which is true of protein hormones in circulation?
Responda
-
Long half-life
-
Short half-life
Questão 13
Questão
The following questions will be about steroid hormones. What are steroid hormones derived from?
Responda
-
Cholesterol
-
Proteins
-
Amines
-
DNA
Questão 14
Questão
Steroid hormones are lipid soluble.
Questão 15
Questão
Steroid hormones are stored in glands.
Questão 16
Questão
Are steroid hormones protein-bound in circulation?
Questão 17
Questão
Which is true of steroid hormones?
Responda
-
Long half-lives
-
Short half-lives
Questão 18
Questão
The following questions will be about amine hormones. Most amine hormones are derived from...?
Responda
-
Tyrosine
-
Phenylalanine
-
Glutamate
-
Aspartate
Questão 19
Questão
Thyroid hormones are amine hormones.
Questão 20
Questão
Which subtype of amine hormone is lipid-soluble?
Questão 21
Questão
Which subtype of amine hormone is water-soluble?
Questão 22
Questão
Which subtype of amine hormone is protein-bound in circulation, thus giving it a long half-life?
Questão 23
Questão
Which subtype of amine hormone is not bound to protein in circulation, giving it a short half-life?
Questão 24
Questão
Which subtype of amine hormones are stored intracellulary in secretory granules?
Questão 25
Questão
What are eicosanoids?
Questão 26
Questão
What are eicosanoids derived from?
Responda
-
Arachidonic acid
-
Diacylglycerol
-
Inositol
-
PIP2
Questão 27
Questão
Which of the following is an example of an eicosanoid?
Responda
-
Prostaglandin
-
Catecholamine
-
Adrenaline
-
Parathyroid hormone
Questão 28
Questão
Which of the following hormones have intracellular receptors that alter gene transcription?
Questão 29
Questão
Which of the following hormones have membrane-bound receptors that initiate second-messenger pathways to change enzyme activity?
Responda
-
Steroid hormones
-
Thyroid hormones
-
Protein/peptide hormones
-
Glycoproteins
-
Catecholamines
Questão 30
Questão
Drag and drop the correct answers to describe the mechanism of steroid hormones.
1. The steroid hormone crosses the membrane as it is [blank_start]lipid[blank_end]-soluble.
2. The steroid hormone binds to its receptor in the cytosol or [blank_start]nucleus[blank_end].
3. The receptor undergoes a [blank_start]conformational shape change[blank_end] that allows it to bind to DNA.
4. The receptor forms a [blank_start]dimer[blank_end] with another receptor unit and binds to DNA.
5. Binding alters [blank_start]transcription[blank_end] of target genes.
Questão 31
Questão
Which of the following can control hormone secretion?
Responda
-
Change in plasma ion concentration
-
Change in plasma nutrient concentration
-
Neurotransmitter release from neurones contacting endocrine cells
-
Upstream hormone/paracrine agents acting on endocrine cells
-
Conscious effort
-
Repetitive limb movement
-
Lipolysis
Questão 32
Questão
Drag and drop the correct labels to describe the anatomy of the pituitary gland.
Questão 33
Questão
During the development of the pituitary gland, the outpouching of what will form the posterior pituitary/neurohypophysis?
Questão 34
Questão
During the development of the pituitary gland, the outpouching of what will form the anterior pituitary/adenohypophysis?
Questão 35
Questão
Drag and drop the correct labels to describe the development of the pituitary gland.
Questão 36
Questão
Which of the following are secreted by the posterior pituitary/neurohypophysis?
Questão 37
Questão
Drag and drop the correct answers to describe the secretion of hormones by the posterior pituitary gland/neurohypophysis.
1. Specific neural stimuli lead to the synthesis of hormones in [blank_start]cell bodies[blank_end] of [blank_start]hypothalamic[blank_end] nuclei.
2. The hormones are transported down the [blank_start]axons[blank_end] of [blank_start]neuroendocrine[blank_end] cells.
3. The hormones are stored in [blank_start]Herring bodies[blank_end] in the nerve terminals.
4. The hormones are released directly into the [blank_start]venous blood[blank_end] of the posterior pituitary.
Responda
-
cell bodies
-
hypothalamic
-
thalamic
-
cortical
-
axons
-
neuroendocrine
-
endocrine
-
paracrine
-
Herring bodies
-
pituicytes
-
venous blood
-
tissue fluid
-
surrounding CSF
Questão 38
Questão
What is the effect of ADH?
Responda
-
Increased water resorption in the kidney
-
Decreased water resorption in the kidney
-
Increase in uterine contractions
-
Stimulation of the adrenal glands
Questão 39
Questão
Oxytocin increases uterine contractions during birth as well as milk ejection during suckling.
Questão 40
Questão
Drag and drop the correct answers to describe the mechanism of secretion of hormones from the anterior pituitary/adenohypophysis.
1. Specific neural stimuli lead to [blank_start]synthesis[blank_end] and release of [blank_start]hypothalamic[blank_end] hormones.
2. Hypothalamic hormones are released by [blank_start]neuroendocrine[blank_end] cells into blood vessels at the [blank_start]median eminence[blank_end].
3. The hypothalamic hormones travel down [blank_start]portal blood vessels[blank_end].
4. The hypothalamic hormones control release of anterior pituitary hormones.
Questão 41
Questão
Which part of the pituitary gland receives direct supply from the hypophyseal arteries?
Questão 42
Questão
Drag and drop the correct labels to describe the vasculature of the pituitary gland.
Responda
-
Supraoptic nuclei
-
Paraventricular nuclei
-
Superior hypophyseal artery
-
Infundibulum
-
Inferior hypophyseal artery
-
trabecular artery
-
Hypophyseal veins
-
Endocrine cells
-
Anterior pituitary/adenohypophysis
-
Posterior pituitary/neurohypophysis
Questão 43
Questão
Which of the following are secreted by the anterior pituitary/adenohypophysis?
Questão 44
Questão
What do the hypothalamic hypophysiotrophic hormones do?
Responda
-
Stimulate endocrine cells in the anterior pituitary/adenohypophysis to secrete hormones
-
Stimulate the release of hormones from the Herring bodies in the posterior pituitary/neurohypophysis
-
Increase body temperature
-
Initiate reproductive behaviour
Questão 45
Questão
Drag and drop the correct labels to describe the effect of hypothalamic hypophysiotrophic hormones on the anterior pituitary/adenohypophysis.
Responda
-
Thyrotropin-releasing hormone
-
Dopamine
-
Corticotropin-releasing hormone
-
Gonadotrophin-releasing hormone
-
Growth-hormone releasing hormone
-
Somatostatin
-
Thyrotroph cells
-
Lactotroph cells
-
Corticotroph cells
-
Gonadotroph cells
-
Somatotroph cells
-
Thyroid-stimulating hormone
-
Prolactin
-
Adrenocorticotrophic hormone
-
Luteinising hormone
-
Follicle-stimulating hormone
-
Growth hormone