34378499
Descrição
Quiz por ACAPUN INSTITUTE, atualizado more than 1 year ago
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Criado por ACAPUN INSTITUTE
quase 3 anos atrás
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|
Questão 1
Questão
Which of the following drugs is useful in treating dermatologic manifestations of an allergic response?
Responda
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a. Diazepam
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b. Atropine
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c. Hexylresorcinol
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d. Chlorpheniramine
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e. Phenoxybenzamine
Questão 2
Questão
Cimetidine is used therapeutically to
Responda
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a. Stimulate respiration
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b. Protect against anaphylaxis
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c. Decrease gastric acid secretion
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d. Hasten excretion of barbiturates
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e. Dilate smooth muscles of the bronchioles
Questão 3
Questão
Gastric acid secretion has been shown to be most effectively reduced with the use of
Responda
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a. Adrenal steroids
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b. Anticholinergic drugs
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c. Serotonin antagonists
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d. H1-histamine receptor antagonists
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e. H2-histamine receptor antagonists
Questão 4
Questão
Drug-mediated inhibition of H2-histamine receptors is most useful in treating
Responda
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a. Asthma
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b. Anaphylaxis
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c. Contact dermatitis
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d. Gastric hyperacidity
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e. Localized allergic reactions
Questão 5
Questão
Which of the following antihistamines is most commonly used as preoperative medication?
Responda
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a. Meclizine
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b. Cyclizine
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c. Promethazine
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d. Dimenhydrinate
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e. Chlorpheniramine
Questão 6
Questão
Use of diphenhydramine (Benadryl) in controlling the symptoms of parkinsonism is based upon which of the following effects?
Responda
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a. Anticholinergic
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b. Local anesthetic
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c. Adrenergic-blocking
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d. CNS depressant on the midbrain
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e. Stimulant to dopaminergic nerves in the basal ganglia
Questão 7
Questão
The mechanism of action of H1 antihistamines is
Responda
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a. MAO enzyme inhibition
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b. competitive antagonism
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c. physiologic antagonism
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d. noncompetitive antagonism
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e. inhibition of release of bound histamine
Questão 8
Questão
Which of the following drugs is often used to treat trigeminal neuralgia?
Responda
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a. clonazepam
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b. carbamazepine
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c. acetazolamine
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d. succinylcholine
Questão 9
Questão
The use of epinephrine for local hemostasis during surgery might result in
Responda
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a. hypoglycemia
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b. cardiac arrthymia
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c. an acute asthma attack
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d. a drastic drop in blood pressure
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e. any of the above
Questão 10
Questão
The highest risk associated with use of oral contraceptives is
Responda
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a. hepatic necrosis
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b. permanent sterility
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c. cancer of the breast
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d. cancer of the uterus
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e. thromboembolic disorders
Questão 11
Questão
Factors common to all forms of drug abuse include EXCEPT
Responda
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a. miosis
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b. tolerance
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c. physical dependence
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d. psychological dependence
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e. any of the above
Questão 12
Questão
Alcoholic euphoria results from
Responda
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a. increased activity of the cerebellum
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b. increased activity of the cerebral areas
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c. increased activity of the spinal synapses
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d. decreased activity of the medullary centers
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e. removal of inhibitory activity of the cortex
Questão 13
Questão
Sulfonyl ureas cause insulin secretion by
Responda
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a. adrenergic simulation
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b. cholinergic stimulation
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c. direct stimulation of pancreatic beta cells
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d. dependent of glucosa
Questão 14
Questão
If a patient requiring an extraction reports that he is on dicoumarol therapy, the laboratory test most valuable in evaluating the surgical risk is
Responda
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a. clotting time
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b. bleeding time
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c. sedimentation rate
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d. complete blood cell count
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e. plasma prothrombin time
Questão 15
Questão
A drug has a half-life of 4 hours. If 2 gms are given every 4 hrs what will be the amount in gms in the body immediately after the third dose?
Responda
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a. 1.5
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b. 2.0
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c. 3.5
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d. 4.0
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e. 6.0
Questão 16
Questão
Which of the following combinations represents acceptable agonistantagonist pairs in antidotal therapy?
Responda
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a. morphine-naloxone
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b. dicoumarol-protamine
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c. warfarin-phenylbutazone
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d. carbon monoxide-carbon dioxide
Questão 17
Questão
The various insulin preparations useful in the treatment of diabetes mellitus differ primarily in
Responda
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a. locus of action
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b. mechanism of action
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c. mode of transformation
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d. onset and duration of action
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e. none of the above
Questão 18
Questão
Displacement of a drug from protein binding sites is expected to increase the
Responda
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a. drug effect observed
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b. duration of drug effect
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c. dose required for a given effect
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d. none of the above
Questão 19
Questão
In an addisonian crisis (hypoaldosteronism) resulting from stress from a minor dental procedure, the patient should be treated immediately with
Responda
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a. 0.5 ml norepinephrine
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b. 5 mg. prednisolone acetate
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c. 1% triamcinolone acetonide
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d. 0.5 ml, 1:1000 epinephrine
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e. 2 ml (100 mg) hydrocortisone hemisuccinate
Questão 20
Questão
Drug A inhibits the biotransformation of Drug B. The duration of action of drug B in the presence of drug A will usually be
Responda
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a. shortened
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b. prolonged
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c. unchanged
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d. equal
Questão 21
Questão
In which of the following groups of drugs is there the most consistency in chemical structure?
Responda
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a. diuretics
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b. antiepileptics
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c. local anesthetics
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d. general anesthetics
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e. nonbarbiturate sedatives
Questão 22
Questão
Cimetidine is administered to
Responda
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a. aid in sleeping
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b. relieve asthma
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c. inhibit gastric secretion
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d. relieve cold and flu symptoms
Questão 23
Questão
Which of the following anticancer drugs can be classified as an antimetabolite?
Responda
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a. cisplatin
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b. lomustine
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c. vincristine
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d. methotrexate
Questão 24
Questão
Which of the following hormones acts to elevate blood concentration of ionic calcium?
Responda
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a. glucagon
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b. parathyroid
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c. aldosterone
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d. thyrotropin
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e. thyrocalcitonin
Questão 25
Questão
Disorientation, confusion, and hallucinations resulting from an overdose of scopolamine are most efficaciously treated by administering
Responda
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a. atropine
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b. levodopa
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c. acetylcholine
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d. physostigmine
Questão 26
Questão
Developed hyporeactivity to a drug is
Responda
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a. tolerance
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b. antagonism
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c. detoxification
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d. desensitization
Questão 27
Questão
Absorption of a drug from the intramuscular site of administration may be slowed by
a. excercise
b. vasoconstriction
c. the presence of congestive heart failure
d. administering the drug as an insoluble complex
Responda
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1. a and b
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2. b only
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3. b, c, and d
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4. b and d
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5. all of the above
Questão 28
Questão
Salicylism includes which of the following?
a. nausea
b. tinnitus
c. vomiting
d. gastrointestinal bleeding
Responda
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1. a, b, and c
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2. a, b, and d
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3. a and c only
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4. b, c, and d
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5. all of the above
Questão 29
Questão
Which of the following are important criteria for the adequate clinical evaluation of a new drug?
a. comparison with a placebo
b. evaluation of side effects
c. utilization of control groups
d. comparison with a standard drug
e. double blind experimental design
Responda
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1. a, b, c, and d
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2. a, b, d, and e
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3. a, c, d, and e
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4. b, c, and e
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5. b, d and e only
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6. all of the above
Questão 30
Questão
Each of the following agents has a long duration of action due to the presence of liver generated active metabolites EXCEPT
Responda
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a. diazepam
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b. oxazepam
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c. flurazepam
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d. chlordiazepoxide
Questão 31
Questão
Each of the following statements relates to the general aspects of toxicology EXCEPT
Responda
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a. most drugs exert a single action
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b. toxicity is both time and dose dependent
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c. toxicity can be due to overdosage of a drug
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d. symptoms of toxicity can be anything ranging from nausea to death
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e. for some drugs, even a minimal concentration can be harmful
Questão 32
Questão
The central actions of ethyl alcohol are not synergistic with which of the following?
Responda
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a. diazepam
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b. meperidine
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c. pentobarbital
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d. chlorpromazine
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e. methylphenidate
Questão 33
Questão
A heroin dependent patient should not be given nalbuphine (Nubain) for pain because
Responda
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a. it has no analgesic properties
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b. it may produce respiratory depression
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c. as a mixed agonist-antagonist, it can elicit withdrawal symptoms
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d. the high abuse potential of nalbuphine may add to the patient's problems
Questão 34
Questão
All of the following methods of drug biotransformation are classified as synthetic except:
Responda
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a. N-alkylation
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b. O-dealkylation
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c. sulfate conjugation
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d. glucuronide conjugation
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