34379550
Descrição
Quiz por ACAPUN INSTITUTE, atualizado more than 1 year ago
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Criado por ACAPUN INSTITUTE
quase 3 anos atrás
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Questão 1
Questão
Atropine and propantheline exert their effects on peripheral structures by
Responda
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a. preventing release of acetylcholine
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b. preventing synthesis of acetylcholine
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c. enhancing destruction of acetylcholine
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d. competeing with acetylcholine for receptor sites
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e. producing physiologic effects opposite to those of acetylcholine
Questão 2
Questão
Neostigmine produces its effect by physostigmine. These differ from the insecticides and nerve gases listed below in that they are reversible and can be used clinically; the latter are irreversible
Responda
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a. depressing acetylcholinesterase release
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b. inhibiting acetylcholinesterase activity
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c. increasing the rate of acetylcholine synthesis
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d. acting like acetylcholine at ganglionic sites
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e. increasing the amount of acetylcholine released from nerve terminals
Questão 3
Questão
Organophosphate insecticides and nerve gases inhibit the action of which of the following enzymes?
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a. adenylate cyclase
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b. monoamine oxidase
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c. phosphodiesterase
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d. acetylcholinesterase
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e. carbonic anhydrase
Questão 4
Questão
Drugs which are additive with or potentiate the effects of acetylcholine include
(a) methacholine
(b) scopolamine
(c) pralidoxime
(d) neostigmine
(e) pilocarpine
Responda
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1. (a), (b), and (c)
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2. (a), (c), and (d)
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3. (a), (d) and (e)
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4. (b), (d), and (e)
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5. (c), (d) and (e)
Questão 5
Questão
Which of the following drugs is best to administer after poisoning by an organophosphate cholinesterase inhibitor?
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a. atropine
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b. phenytoin
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c. pralidoxime
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d. propantheline
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e. phenobarbital
Questão 6
Questão
Which of the following compounds is a ganglionic blocking agent?
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a. curarine
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b. edrophonium
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c. mecamylamine
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d. succinylcholine
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e. gallamine triethodide
Questão 7
Questão
Which of the following acts by antagonizing cholinesterase?
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a. atropine
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b. muscarine
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c. neostigmine
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d. pilocarpine
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e. acetylcholine
Questão 8
Questão
When neostigmine is administered before acetylcholine, the action of acetylcholine will be
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a. blocked
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b. enhanced and prolonged
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c. less intense and of shorter duration
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d. none of the above. The action of acetylcholine is not affected by neostigmine
Questão 9
Questão
Neostigmine can stimulate denervated skeletal muscle because it
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a. is a congener of acetylcholine
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b. is a competitive blocking agent
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c. has no effect on acetylcholinesterase
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d. is more potent than diisopropylfluorophosphate
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e. is capable of acting directly on the end-plate
Questão 10
Questão
Which of the following is used to prevent laryngospasm?
Responda
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a. atropine
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b. epinephrine
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c. diazepam (Valium)
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d. neostigmine (Prostigmine)
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e. succinylcholine (Anectine)
Questão 11
Questão
In treating xerostomia, which of the following might be prescribed?
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a. atropine
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b. ephedrine
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c. neostigmine
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d. scopolamine
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e. mecamylamine
Questão 12
Questão
Which of the following drugs is most likely to dry secretions in the oral cavity?
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a. diazepam
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b. promethazine
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c. physostigmine
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d. propantheline
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e. diphenhydramine
Questão 13
Questão
The most useful drug to induce salivation is one which has properties that are
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a. adrenergic
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b. cholinergic
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c. ganglionic blocking
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d. adrenergic blocking
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e. cholinergic blocking
Questão 14
Questão
Drugs that are commonly used in the control of excessive salivation include
(a) meprobamate
(b) atropine
(c) methantheline
(d) codeine
(e) chlorpromazine
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1. (a) and (b) only
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2. (a), (b), and (c)
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3. (b) and (c) only
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4. (b), (c), and (d)
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5. (d) and (e)
Questão 15
Questão
Drugs that are commonly used in the control of excessive salivation include
(a) meprobamate
(b) atropine
(c) methantheline
(d) codeine
(e) chlorpromazine
Responda
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1. (a) and (b) only
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2. (a), (b), and (c)
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3. (b) and (c) only
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4. (b), (c), and (d)
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5. (d) and (e)
Questão 16
Questão
Tachycardia in a patient administered with atropine or scopolamine results from
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a. release of adrenal catecholamines
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b. blockade of vagus nerve activity
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c. blockade of the nicotinic cholinergic receptor
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d. stimulation of the alpha adrenergic receptor
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e. stimulation of the beta adrenergic receptor
Questão 17
Questão
All of the following are possible effects of cholinomimetic drugs except
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a. mydriasis
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b. bradycardia
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c. increased peristalsis
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d. stimulation of sweat glands
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e. increased secretion by bronchial glands
Questão 18
Questão
A paralyzing dose of succinylcholine initially elicits
Responda
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a. CNS stimulation
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b. CNS depression
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c. decreased salivation
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d. muscle fasiculation
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e. extrapyramidal reactions
Questão 19
Questão
Based on its known mechanism and sites of action, scopolamine should theoretically be useful in
(a) treatment of peptic ulcer
(b) providing euphoria and amnesia prior to surgery
(c) relieving bronchoconstriction
(d) relieving some of the symptoms of Parkinson disease
(e) visualization of the retina
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1. (a), (b), (d) and (e)
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2. (a), (b), and (e) only
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3. (a),and (c)
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4. (b) and (e) only
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5. All of the above
Questão 20
Questão
Symptoms of poisoning by an organophosphate insecticide include all of the following except:
Responda
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a. skeletal muscle fasiculation
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b. excessive salivation
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c. bronchoconstriction
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d. hot, dry skin
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e. diarrhea
Questão 21
Questão
All of the following symptoms are associated with neostigmine poisoning except
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a. diarrhea
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b. salivation
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c. convulsions
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d. bonchiolar constriction
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e. skeletal muscle paralysis
Questão 22
Questão
Symptoms of atropine poisoning in man include
(a) decreased intraocular pressure
(b) burning dry mouth
(c) nausea, vomiting and diarrhea
(d) hyperthermia
(e) orthostatic hypotension
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1. (a) and (c)
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2. (b) and (d)
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3. (b), (d), and (e)
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4. (d) and (e)
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5. All of the above
Questão 23
Questão
The most likely signs or symptoms of overdosage with atropine are
Responda
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a. CNS excitation and tachycardia
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b. intestinal cramps and diarrhea
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d. ptyalism and increased sweating
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e. constriction of the pupils and blurring of vision
Questão 24
Questão
Disorientation, confusion and hallucinations resulting from an overdose of scopolamine are most efficaciuosly treated by administering
Responda
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a. atropine
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b. levodopa
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c. acetylcholine
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d. physostigmine
Questão 25
Questão
The immediate cause of death from irreversible cholinesterase inhibitors is
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a. shock
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b. convulsion
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c. cardiac arrhythmia
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d. respiratory paralysis
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e. dehydration from vomiting and diarrhea
Questão 26
Questão
Each of the following is a symptom of cholinergic crisis except
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a. bradycardia
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b. lacrimation
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c. vasoconstriction
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d. extreme salivation
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e. weakness of voluntary muscles
Questão 27
Questão
Succinylcholine is a short-acting neuromuscular junction blocking agent useful for providing a brief paralysis to aid in intubating patients. It is short-acting because
Responda
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a. it is subject to rapid metabolism in the liver
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b. it rapidly redistributes away from the NMJ
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c. it is subject to inactivation by plasma esterases
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d. it undergoes rapid inactivation in the GI tract
Questão 28
Questão
Atropine-like drugs are classed as
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a. anti-adrenergic
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b. cholinomimetic
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c. sympatholytic
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d. anti-cholinergic
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e. sympathomimetic
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