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Pharmacology VI

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Praxis Tests: Pharmacology Quiz sobre Pharmacology VI, criado por ACAPUN INSTITUTE em 08-11-2021.
ACAPUN INSTITUTE
Quiz por ACAPUN INSTITUTE, atualizado more than 1 year ago
ACAPUN INSTITUTE
Criado por ACAPUN INSTITUTE aproximadamente 3 anos atrás
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Resumo de Recurso

Questão 1

Questão
Quinidine is principally used to treat
Responda
  • a. Hypertension
  • b. Angina pectoris
  • c. Congestive hear failure
  • d. Supraventricular tachyarrhythmias

Questão 2

Questão
Quinidine is used to treat
Responda
  • a. Hypertension
  • b. Angina pectoris
  • c. Atrial fibrillation
  • d. Ventricular fibrillation
  • e. Congestive hear failure

Questão 3

Questão
Verapamil is most efficacious in the treatment of
Responda
  • a. Atrial fibrillation
  • b. Atrial tachycardia
  • c. Ventricular tachycardia
  • d. Catecholamine-induced arrhythmias

Questão 4

Questão
Which of the following drugs is most useful in treating or preventing angina pectoris?
Responda
  • a. Digitalis
  • b. Quinidine
  • c. Propranolol
  • d. Procainamide
  • e. Pentobarbital

Questão 5

Questão
Each of the following drugs can be used in the prevention and treatment of angina pectoris EXCEPT
Responda
  • a. Digitalis
  • b. Propranolol
  • c. Nitroglycerin
  • d. Isosorbide dinitrate
  • e. Pentaerythritol tetranitrate

Questão 6

Questão
All of the following drugs are useful in the treatment of hypertension EXCEPT
Responda
  • a. Ephedrine
  • b. Reserpine
  • c. Methyldopa
  • d. Thiazide diuretics

Questão 7

Questão
Digitalis is useful in the treatment of which of the following conditions?
Responda
  • a. Atrial fibrillation
  • b. Congestive heart failure
  • c. Paroxysmal atrial tachycardia
  • d. All of the above

Questão 8

Questão
All of the following drugs are useful in the treatment of cardiac arrhythmias EXCEPT
Responda
  • a. Digitalis
  • b. Lidocaine
  • c. Phenytoin
  • d. Procainamide
  • e. Aminophylline

Questão 9

Questão
The drug of choice for initial therapy for mild hypertension is
Responda
  • a. Reserpine
  • b. Guanethidine
  • c. Phenobarbital
  • d. Chlorothiazide
  • e. Alpha-methyldopa

Questão 10

Questão
Which of the following antihypertensives are usually reserved for treatment of severe hypertension?
Responda
  • a. Sedatives and reserpine
  • b. Thiazide diuretics and reserpine
  • c. Sedatives and thiazide diuretics
  • d. Guanethidine and ganglionic blocking agents

Questão 11

Questão
Which of the following beta-adrenergic receptor blocking agents is thought to be cardioselective?
Responda
  • a. Nadolol
  • b. Timolol
  • c. Metoprolol
  • d. Propranolol

Questão 12

Questão
Antiarrhythmic drugs, such as quinidine, suppress certain cardiac arrhythmias by
Responda
  • a. Stimulating the beta-adrenergic receptor
  • b. Suppressing cardiac ATP-ase activity
  • c. Increasing ectopic pacemaker activity
  • d. Increasing the refractory period of cardiac muscle

Questão 13

Questão
Most drugs useful in the treatment of cardiac arrhythmias act primarily by
Responda
  • a. Blocking Purkinje fibers
  • b. Blocking the alpha-adrenergic receptor
  • c. Suppressing SA node impulse formation
  • d. Causing a positive inotropic effect
  • e. Increasing the refractory period of cardiac muscle

Questão 14

Questão
The most important pharmacologic action of drugs that suppress cardiac arrhythmias is
Responda
  • a. Blockade of the vagus nerve
  • b. Stimulation of cardiac ATP-ase activity
  • c. Blockade of the Beta-adrenergic receptor
  • d. Stimulation of the beta-adrenergic receptor
  • e. Increased refractory period of cardiac muscle

Questão 15

Questão
Lidocaine produces its antiarrhythmic effects by
Responda
  • a. Increasing AV conduction
  • b. Decreasing cardiac excitability
  • c. Increasing cardiac conduction velocity
  • d. Increasing spontaneous pacemaker activity

Questão 16

Questão
When digitalis is used in atrial fibrillation, the therapeutic objective is to
Responda
  • a. Abolish cardiac decompensation
  • b. Inhibit vagal impulses to the heart
  • c. Decrease the rate of A-V conduction
  • d. Increase the rate of cardiac repolarization
  • e. Produce a decrease in the rate of atrial contraction

Questão 17

Questão
Nitroglycerin dilates the coronary arteries in angina pectoris by
Responda
  • a. Decreasing the heart rate reflexly
  • b. Increasing the metabolic work of the myocardium
  • c. Direct action on smooth muscle in the vessel walls
  • d. Increasing the effective refractory period in the atrium
  • e. Blocking beta-adrenergic receptors

Questão 18

Questão
Propranolol is of value in treating angina pectoris because it
Responda
  • a. Has a direct action on vascular smooth muscle
  • b. Blocks autoregulatory mechanisms in the heart
  • c. Inhibits oxygen metabolism in cardiac cells
  • d. Provides relief within seconds of an acute anginal attack
  • e. Prevents chronotropic responses to endogenous epinephrine emotions and exercise

Questão 19

Questão
Administration of angiotensin results in
Responda
  • a. Anti-inflammatory effects
  • b. Antihistaminic effects
  • c. Increased blood pressure
  • d. Increased heart rate
  • e. A sedative effect

Questão 20

Questão
The primary antihypertensive effect of captopril (Capoten) is due to accumulation of
Responda
  • a. Serotonin
  • b. Angiotensin I
  • c. Angiotensin III
  • d. Bradykinin metabolites

Questão 21

Questão
Administration of angiotensin results in
Responda
  • a. A sedative effect
  • b. Increased heart rate
  • c. Increased blood pressure
  • d. Antihistaminic effects
  • e. Anti-inflammatory effects

Questão 22

Questão
Which of the following is NOT characteristic of the thiazide diuretics?
Responda
  • a. Increase renal excretion of sodium and chloride
  • b. Increase renal excretion of potassium
  • c. Increase the toxicity of digitalis
  • d. Exacerbate existing diabetes
  • e. Cause hypokalemia
  • f. Cause hypoglycemia

Questão 23

Questão
The most useful diuretic drugs act by
Responda
  • a. Increasing the glomerular filtration rate
  • b. Decreasing the renal reabsorption of sodium
  • c. Decreasing the renal excretion of chloride
  • d. Increasing the renal reabsorption of potassium
  • e. Increasing the secretion of antidiuretic hormone

Questão 24

Questão
Which of the following drugs act by inhibiting renal reabsorption of sodium?
Responda
  • a. Urea
  • b. Chlorothiazide
  • c. Theophylline
  • d. digitalis glycosides
  • e. Procainamide

Questão 25

Questão
Digoxin exerts its positive inotropic effect by
Responda
  • a. Activation of adenylcyclase
  • b. Inhibition of phosphodiesterase
  • c. An agonist effect of beta-receptors
  • d. Inhibition of Na+, K+ ATPASE leading to increased calcium influx
  • e. Decreasing the amount of calcium available for excitationcontraction coupling

Questão 26

Questão
Digitoxin is effective in the treatment of cardiac failure because it
Responda
  • a. Is primarily a diuretic
  • b. Reduces the ventricular rate
  • c. Decreases abnormal cardiac rhythms
  • d. Produces peripheral vasoconstriction
  • e. Has a positive cardiac inotropic action

Questão 27

Questão
The primary action of therapeutic doses of digitalis on cardiac muscle is an increase in
Responda
  • a. Force of contraction
  • b. Ventricular excitability
  • c. Refractory period of the atrial muscle
  • d. Refractory period of the ventricular muscle
  • e. Rate of conduction of impulse to the muscle

Questão 28

Questão
The beneficial effects of digitalis in congestive heart failure result in part from the fact that digitalis causes a. A decrease in end-diastolic volume b. A decrease in end-diastolic pressure c. An increase in stroke volume and cardiac output d. A decrease in central venous pressure e. A decrease in rate of the hear where tachycardia exists
Responda
  • a) (a), (b) and (c)
  • b) (a) and (c) only
  • c) (c) and (d)
  • d) (e) only
  • e) All of the above

Questão 29

Questão
The cardiac glycosides will increase the concentration of which ion in an active heart muscle?
Responda
  • a. Sodium
  • b. Bromide
  • c. Calcium
  • d. Chloride
  • e. Potassium

Questão 30

Questão
Which of the following ions augments the inotropic effect of digitalis?
Responda
  • a. Sodium
  • b. Lithium
  • c. Calcium
  • d. Chloride
  • e. Magnesium

Questão 31

Questão
In the treatment of congestive heart failure, digitalis glycosides generally decrease all of the following EXCEPT
Responda
  • a. Edema
  • b. Urine flow
  • c. Heart size
  • d. Heart rate
  • e. Residual diastolic volume

Questão 32

Questão
The mechanism of action of prazosin, an antihypertensive agent is to
Responda
  • a. Block beta-adrenergic receptors
  • b. Inhibit formation of angiotensin II
  • c. Inhibit nerve-induced release of norepinephrine
  • d. Stimulate central inhibitory alpha-adrenergic receptors
  • e. Inhibit the postsynaptic of norepinephrine on vascular smooth muscle

Questão 33

Questão
Which of the following owes a significant amount of its antihypertensive effect to a central action?
Responda
  • a. Methyldopa
  • b. Metoprolol
  • c. Hydralazine
  • d. Propranolol
  • e. Guanethidine

Questão 34

Questão
Which of the following drugs is thought to reduce arterial blood pressure by activating alpha receptors in the vasomotor center of the medulla?
Responda
  • a. Prazosin
  • b. Clonidine
  • c. Propranolol
  • d. Guanethidine
  • e. Chlorothiazide

Questão 35

Questão
Propranolol (Inderal) can be useful in the treatment of hypertension because it blocks
Responda
  • a) (a) and (b)
  • b) (a) and (d)
  • c) (b), (c) and (d)
  • d) (c), (d) and (e)
  • e) (c) and (e) only

Questão 36

Questão
One of the proposed mechanisms of the antihypertensive effect of beta-adrenergic receptor blocking agents is
Responda
  • a. Sedation
  • b. A diuretic effect
  • c. An antirenin effect
  • d. A vagal blocking effect
  • e. An increase in cardiac output

Questão 37

Questão
Selective beta-1 adrenergic agonists will produce which of the following effects?
Responda
  • a. Glycogenolysis
  • b. Increased cardiac output
  • c. Decreased diastolic pressure
  • d. Decreased peripheral resistance
  • e. Relaxation of bronchial smooth muscle

Questão 38

Questão
Ototoxicity with deafness may encountered occasionally in patients taking which of the following diuretic agents?
Responda
  • a. Osmotic
  • b. Thiazide
  • c. Mercurial
  • d. High-ceiling

Questão 39

Questão
Ototoxicity with deafness may encountered occasionally in patients taking which of the following diuretic agents?
Responda
  • a. Osmotic
  • b. Thiazide
  • c. Mercurial
  • d. High-ceiling

Questão 40

Questão
Symptoms of digitalis toxicity include all of the following EXCEPT
Responda
  • a. Extrasystoles
  • b. Nausea and vomiting
  • c. Yellow-green vision
  • d. A-V conduction block
  • d. Chlorothiazide
  • e. Acetylsalicylic acid

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