Cytogenetics

A structural chromosomal abnormality is described by which of the following?

How many chromosomes could someone with polypoidy have?

You can survive with only one X chromosome.

Dispermy results in?

The most common pregnancy complication is [blank_start]spontaneous abortions[blank_end].

A baby is born with feet shaped like rockers and clenched hands. The baby had poor prenatal growth. Which of the following describe the condition of the baby?

All of the following include trisomy. Down Syndrome is a defect in chromosome [blank_start]21[blank_end]. Edwards Syndrome is a defect in chromosome [blank_start]18[blank_end]. Patau is a defect in chromosome [blank_start]13[blank_end].

Turner Syndrome is a result of nondisjunction of maternal chromosomes.

The Turner Syndrome genotype is [blank_start]X[blank_end]. The Klinefelter genotype is [blank_start]XXY[blank_end]. The Tripe X Syndrome genotype is [blank_start]XXX[blank_end]. The last sex chromosome disorder involves paternal meiosis II nondisjunction and is called [blank_start]47, XYY[blank_end]

Which of the following (more than one?) could be caused by maternal nondisjuction?

Which of the following would result in a phenotypically normal individual?

Which of the following would describe a male with a balanced reciprocal translocation involving 3q and 17p?

A 4 month old female infant is not obtaining normal developmental milestones and has failure to thrive. Chromosome analysis reveals an abnormality; one copy of chromosome 21 has extra genetic material attached to the long arm. The origin of the extra material is not obvious. All other chromosomes appear normal. How would you interpret this finding?

A monosomy is worse than a trisomy.

A baby is born with only one chromosome 15 with the two q arms attached at one centromere. Which of the following most correctly describes the baby's condition.