Cholinergic Drugs

Descrição

Tests for Ewa
Leon Schwarze
Quiz por Leon Schwarze, atualizado 7 meses atrás
Leon Schwarze
Criado por Leon Schwarze 7 meses atrás
15
0

Resumo de Recurso

Questão 1

Questão
Which drugs are used for glaucoma [blank_start]Pilocarpine[blank_end] [blank_start]Carbachol[blank_end]
Responda
  • Pilocarpine
  • Suprarenin
  • Carbachol
  • Benzatropine

Questão 2

Questão
What are the symptoms of nerve gas poisoning. Organize symptoms into groups:
Responda
  • Nicotinic signs: Neuromuscular (twitching, fasciculation, paralysis)
  • Central signs: Headache, drowsiness, disorientation, coma or generalized convulsion
  • Muscarinic signs: Miosis, nausea, salvitation, vomiting, diarrhea, sweating, bradycardia, bronchial constriction.
  • Treatment: Atropine (muscarinic receptor antagonist), diazepam (for convulsion) and pralidoxime or obidoxime (reactivators)

Questão 3

Questão
What are indications for Benzatropine
Responda
  • Parkinson’s disease
  • blurred vision
  • fast heartbeats
  • vomiting or constipation
  • little or no urination

Questão 4

Questão
Side effects of atropine
Responda
  • hallucinations
  • dry mouth
  • constipation
  • dryness of skin
  • tachycardia
  • urine retention
  • Blocking of acetylcholine

Questão 5

Questão
Rivastigmine - Method of Action and indications of
Responda
  • Reversible inhibitor of acetylcholinesterase (Indirect acting cholinergic agonist)
  • Alzheimer’s disease, dementia
  • quite well absorbed by oral route and crossing well the blood brain barrier
  • Organophosperus poisoning
  • Parkinson´s Disease
  • symptomatical dehydration

Questão 6

Questão
Tropicamide Indications
Responda
  • Dilation of the pupil (connected with examination before & after surgery)
  • Mydriasis
  • Countering of Opiod abuse opthalamic symptoms

Questão 7

Questão
3 Alzheimer Drugs
Responda
  • Donepezil
  • Rivastigmine
  • Gelantamine

Questão 8

Questão
Muscarine Poisoning:
Responda
  • Increased Salivation, sweating, lacrimation
  • Bradycardia, Block, Hypertension
  • Generally subsides within 2 Hours
  • Dyspnoe, blurrred vision, abdominal pain with nausea and diarrhea
  • The specific antigen is Atropine

Questão 9

Questão
Neostigmine
Responda
  • Reversible Inhibitor of acetylcholinesterase
  • Prioritizes Digestive tract and Bladder over CVS & CNS
  • Treatment in myasthenia gravis, posoperative atony (intestine/bladder)
  • neostigmine indirectly stimulates both nicotinic and muscarinic receptors
  • reversible cholinesterase inhibitor

Questão 10

Questão
Clinical Indications of parasympathic agonists
Responda
  • Bradycardia, Hypotension, Coronary insufficiency
  • Cardiac Block
  • Hyperthyroidism
  • Asthma
  • peptic Ulcers

Questão 11

Questão
Method of Action of Buscopan
Responda
  • peripheral effects similar to those of atropine
  • sedative and tranquillizing action and has an amnestic effect
  • treat abdominal cramping and irritable bowel syndrome => antispasmodics acting on the smooth musculature
  • used as an antiemetic agent in the prevention of motion sickness

Questão 12

Questão
Indication for Atropine
Responda
  • antidote in muscarinic poisoning
  • biliary and renal colic pain used as antispasmodic for painful smooth muscle spasms
  • cardiology: treatment of bradykardia and block.
  • anesthesiology : prevention of respiratory tract secretion ● bronchospasm ● laryngospasm ● reflexes
  • Atrial Fibrilation

Questão 13

Questão
How does Dopamine act?
Responda
  • D1 – stimulated at low concentration. Induces renal, mesenteryc and coronary vasodilation. Increase renal blood flow and GFR, Na excretion.
  • B1 – Stimulated at higher concentration. Postitive inotropic effect
  • A1 stimulated at high concentrations.Induces vasoconstriction

Questão 14

Questão
Side effects of epinephrine
Responda
  • fear anxiety, restlessness, tremor
  • hypertension & Cardiac arrythmias, can cause anginal pain
  • cerebral haemorrhage
  • Worse in hyperthyroid and hypersensitive patients.

Questão 15

Questão
Isoprenaline indications
Responda
  • bradycardia
  • atrioventricular block

Questão 16

Questão
Isoprenaline has only cardiovascular indications
Responda
  • True
  • False

Questão 17

Questão
Drugs used to prevent premature labour and receptors
Responda
  • Salbutamol (short-acting β2 adrenergic receptor agonist)
  • Terbutaline (beta‑adrenergic agonist)
  • Ritodrine (short-acting β2 adrenoreceptor agonist)

Questão 18

Questão
short-acting β2 adrenergic receptor agonist / β2 Stimulants are used in prevention of premature labour / preterm delivery, they act on the utereine smooth muscle cell β2 receptors causing relaxation
Responda
  • True
  • False

Questão 19

Questão
short-acting β2 & 3 adrenergic receptor antagonist are used in prevention of premature labour / preterm delivery, they act on the utereine smooth muscle cell β3 receptors causing relaxation
Responda
  • True
  • False

Questão 20

Questão
Asthma treatment
Responda
  • Epinephrine for asthma attacks: Stimulates α1, α2, β1, β2, β3 adrenergic receptors
  • Ipratropium / Atrovent; Muscarinic receptor antagonist reduce the effects of acetylcholine
  • Salbutamol Inhalator relaxing SMC in the airways by acting on β2 receptors (short acting)

Questão 21

Questão
Treatment of bradycardia
Responda
  • done by using beta1 and beta2 agonists.
  • Isoprenaline
  • orciprenaline
  • atropine with clinical monitoring

Questão 22

Questão
Side Efffeects of Norepinephrine
Responda
  • sudden numbness, weakness, or cold feeling anywhere in your body
  • hypertension
  • reduced blood flow in organs, kidney, liver, brain
  • necrosis at site of administration
  • problems with vision, speech, or balance; or severe headache, blurred vision, pounding in your neck or ears

Questão 23

Questão
Nasal drops are Alpha 2 agonists with local effects
Responda
  • True
  • False

Questão 24

Questão
Nasal Drops are Alpha 1 effects with peripheral effects but with local administration they give more localized effects
Responda
  • True
  • False

Questão 25

Questão
Nasal Drops (α1 agonists)
Responda
  • Phenylepinephrine
  • Naphazoline
  • Tymazoline
  • Ksylometazoline

Questão 26

Questão
Indications of Epinephrine
Responda
  • Anaphylactic Shock
  • Cardiac arrest
  • Asthma attack
  • Glaucoma
  • used with local anaesthesia to reduce their effusion from injection site

Questão 27

Questão
Dobutamine
Responda
  • primarily used in congestive heart failure and shock with low cardiac output
  • β1 agonist
  • ide effects include a fast heart rate, an irregular heart beat, and inflammation at the site of injection
  • positive ionotropic action

Questão 28

Questão
Prevention of Asthma Attacks
Responda
  • Salmeterol,
  • formoterol
  • bambuterol
  • Ipratropium

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