4151650
Descrição
Quiz por Melissa Denker, atualizado more than 1 year ago
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Criado por Melissa Denker
quase 9 anos atrás
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Questão 1
Questão
Which connection allows communication between the hypothalamus and anterior pituitary gland?
Responda
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Hypophyseal portal system
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Hypothalamic hypophyseal tract
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Infundibulum
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Sphenoid sinus cavity surrounding the pituitary gland
Questão 2
Questão
Which connection allows communication between the hypothalamus and the posterior pituitary gland?
Responda
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Hypophyseal portal system
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Hypothalamic hypophyseal tract
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Infundibulum
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Sphenoid sinus cavity surrounding the pituitary gland
Questão 3
Questão
Which hormones are produced by the posterior pituitary gland?
Responda
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Oxytocin
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ADH
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Prolactin
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TSH
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FSH/LH
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GH
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ACTH
Questão 4
Questão
What is the correct order of the following anterior pituitary cell types, from most abundant to least abundant?
Responda
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Somatotrophs (50%) Lactotrophs (20%) Corticotrophs (10-15%) Gonadotrophs (10%) Thyrotrophs (5%)
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Somatotrophs (50%) Lactotrophs (20%) Gonadotrophs (10-15%) Corticotrophs (10%) Thyrotrophs (5%)
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Gonadotrophs (50%) Lactotrophs (20%) Corticotrophs (10-15%) Thyrotrophs (10%) Somatotrophs (5%)
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Somatotrophs (50%) Lactotrophs (20%) Corticotrophs (10-15%) Thyrotrophs (10%) Gonadotrophs (5%)
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Corticotrophs (50%) Lactotrophs (20%) Somatotrophs (10-15%) Gonadotrophs (10%) Thyrotrophs (5%)
Questão 5
Questão
What are the 6 hormones released by the anterior pituitary gland?
Responda
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ADH
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Oxytocin
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GH
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FSH/LH
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Prolactin
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ACTH
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TSH
Questão 6
Questão
Which hypothalamic hormone stimulates the secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary gland?
Responda
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Corticotrophic releasing hormone (CRH)
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Thyroid releasing hormone (TRH)
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Growth hormone releasing hormone (GHRH)
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Gonadotrophin releasing hormone (GnRH)
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Dopamine
Questão 7
Questão
Which test results would indicate cranial diabetes insipidus?
Responda
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Water deprivation test - patients are desperate to drink; urine osmolality remains low Response to ADH - DI improves
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Water deprivation test - patients are desperate to drink; urine osmolality stays low Response to ADH - DI does not improve
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Water deprivation test - urine osmolality becomes high (i.e. concentrated) Response to ADH - DI improves
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Water deprivation test - urine osmolality becomes high (i.e. becomes concentrated) Response to ADH - DI does not improve
Questão 8
Questão
What is the correct order for rates of functional pituitary adenomas?
Responda
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Prolactinomas (30%) Cushing's disease (20%) Acromegaly (15%) TSHoma (<1%)
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Prolactinomas (30%) Cushing's disease (20%) TSHomas (15%) Acromegaly (<1%)
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Acromegaly (30%) Cushing's disease (20%) Prolactinomas (15%) TSHoma (<1%)
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Prolactinomas (30%) TSHoma (20%) Acromegaly (15%) Cushing's disease (<1%)
Questão 9
Questão
Describe the process of thyroid hormone production:
1. Iodine is actively transported into the [blank_start]follicular thyroid cells[blank_end] via [blank_start]sodium iodide transporters[blank_end] on the basolateral side of the cell (this is called [blank_start]iodide trapping[blank_end])
2. Iodine diffuses to the luminal side of the cell
3. Iodine is transported into the follicle lumen by [blank_start]pendrin[blank_end], a membrane transporter
4. The follicle cells secrete [blank_start]thyroglobulin[blank_end] (containing ~70 [blank_start]tyrosine[blank_end] amino acids) into the lumen
5. Iodide ions undergo [blank_start]oxidation[blank_end] to form [blank_start]iodine[blank_end] via the action of the enzyme [blank_start]hydrogen peroxidase[blank_end]
6. [blank_start]Organification[blank_end] of the thyroglobulin molecule:
---Iodine binds to tyrosine amino acids within the thyroglobulin molecule via the action of [blank_start]thyroid peroxidase[blank_end]
---This forms [blank_start]monoiodotyrosine[blank_end]
---This undergoes further iodine binding to form [blank_start]diiodotyrosine[blank_end]
---MIT/DIT molecules are coupled to each other
7. If two DIT molecules couple together, [blank_start]T4 (thyroxine)[blank_end] is formed
8. If one MIT molecule couples with one DIT molecule, [blank_start]T3 (triiodothyronine)[blank_end] is formed
Responda
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follicular thyroid cells
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sodium iodide transporters
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iodide trapping
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pendrin
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thyroglobulin
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tyrosine
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oxidation
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iodine
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hydrogen peroxidase
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Organification
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tyrosine peroxidase
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monoiodotyrosine (MIT)
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diiodotyrosine (DIT)
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T4 (thyroxine)
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T3 (triiodothyronine)
Questão 10
Questão
How much more concentrated is iodine in the thyroid than in the blood?
Responda
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x30
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x60
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x90
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x120
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