Phamacotherapeutics - Drugs for Cough & Cold

Descrição

Pharm: Drugs for Cough and Cold
campbellpa2017
Quiz por campbellpa2017, atualizado more than 1 year ago
campbellpa2017
Criado por campbellpa2017 mais de 8 anos atrás
6
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Resumo de Recurso

Questão 1

Questão
Which of the following is/are true regarding antitussive medications? (select all that apply)
Responda
  • Used to suppress coughing
  • May be used long-term
  • Better for dry (non-productive) cough
  • Not very effective at current OTC doses
  • Contraindicated in children < 6 years old

Questão 2

Questão
Why would antitussives be contraindicated?
Responda
  • They cause gastrointestinal symptoms if used over 7 days.
  • Coughing is a defense mechanism which we don't want to suppress.
  • Patient has a productive cough.
  • Patient is < 2 years old
  • All of the above
  • All but A

Questão 3

Questão
What is the mechanism of action of Codeine and what is it's brand name?
Responda
  • Inhibits cough through direct effect on brainstem cough center. Also might inhibit peripheral afferent neurons that initiate coughing.
  • Competes for H1 receptor sites on respiratory tract to reduce secretion and stop coughing
  • Robitussin AC
  • Robitussin DM
  • Delsym

Questão 4

Questão
What is the mechanism of Dextromethorphan and what is/are it's brand names?
Responda
  • Soothing to the airway through vaporization.
  • Inhibits cough reflex by a similar mechanism to Codeine (inhibits cough through direct effect on brainstem cough center) but is a non-narcotic.
  • Inhibits cough reflex by a similar mechanism to Codeine (inhibits cough through direct effect on brainstem cough center) but is a narcotic and provides stronger action.
  • Robitussin AC
  • Robitussin DM
  • Vicks Vaposteam
  • Delsym

Questão 5

Questão
Which two medications are sold as Vicks?
Responda
  • Delsym
  • Menthol
  • Carnauba
  • Camphor
  • Lanolin

Questão 6

Questão
What are some common adverse effects of Codeine?
Responda
  • Fatigue
  • Abdominal pain
  • Drowsiness
  • Dizziness
  • Ataxia

Questão 7

Questão
What are some common side effects of Dextromethorphan?
Responda
  • Confusion
  • Ataxia
  • Irritability
  • Nervousness
  • Excitement

Questão 8

Questão
What is the primary side effect of Benadryl?
Responda
  • Shortness of Breath
  • Ataxia
  • Vomiting
  • Insomnia
  • Drowsiness

Questão 9

Questão
Which drug do the young whippersnappers Robo Trip with?
Responda
  • Robitussin AC
  • Robaxin
  • Diphenhydramine
  • Dextromethorphan
  • Tylenol

Questão 10

Questão
What are some therapeutic benefits of Expectorants?
Responda
  • Compete for H1 receptor sites on respiratory tract to reduce secretion and stop coughing.
  • Facilitate production and ejection of mucus.
  • May increase pulmonary function
  • Prevents respiratory passages from being clogged by thick, viscous secretions.
  • Reduce secretions from upper airway so as to prevent drainage into the lower respiratory tract.

Questão 11

Questão
Which of the following are Adverse Effects of Decongestants?
Responda
  • Headache
  • Dizziness
  • Hypertension
  • Palpitations
  • Seizures
  • Nausea
  • Nervousness

Questão 12

Questão
Which of the following are characteristics of decongestants.
Responda
  • Binds to receptors located on blood vessels of nasal mucosa and stimulate vasoconstriction and resulting in drying up of mucosal vasculature and decreased local congestion
  • Usually beta-2 adrenergic agonists.
  • Usually beta-1 adrenergic agonists.
  • Usually alpha-1 adrenergic agonists.
  • Almost exclusively systemic medications.
  • May be systemic or local medications.
  • Almost exclusively local medications
  • Can cause CNS depression, avoid excessive use
  • Can cause CNS excitation, avoid excessive use

Questão 13

Questão
Which oral decongestant rocks and which one sucks?
Responda
  • Phenylephrine
  • Pseudoephedrine

Questão 14

Questão
When is the best time to take an oral decongestant?
Responda
  • In the morning to reduce the negative consequences of CNS excitation.
  • In the evening to reduce the negative consequences of CNS depression.
  • Any time of day as CNS effects are not often seen in decongestants.
  • In the evening to help congested patients sleep.

Questão 15

Questão
What is the chief concern with Afrin administration and what is its generic name?
Responda
  • Nasal polyps
  • Rebound congestion
  • Epistaxis
  • Oxymetazoline
  • Xylometazoline
  • Phenylephrine

Questão 16

Questão
Choose the correct statements regarding Phenylephrine and Pseudoephedrine. (if you get something incorrect, try flipping the statements)
Responda
  • Phenylephrine is more bioavailable (90%) than Pseudoephedrine (38%)
  • Phenylephrine: a1 adrenergic, weak B adrenergic Pseudoephedrine: a1 and B adrenergic
  • Phenylephrine has CNS effects, Pseudoephedrine does not.
  • Pseudoephedrine has more efficacy data than Phenylephrine.
  • Patients with heart conditions, asthma, and COPD need to be more cautious with Pseudoephedrine and less so with Phenylephrine

Questão 17

Questão
Which of these is NOT a condition in which we should be cautious when prescribing oral decongestants?
Responda
  • Hypertension
  • Hyperthyroidism
  • Diabetes
  • Coronary heart disease
  • Diverticulitis
  • Elevated intraocular pressure
  • Prostatic hypertrophy
  • MAOIs

Questão 18

Questão
Which Histamine mediates allergic response and is therefore what our antihistamine drugs target?
Responda
  • H1
  • H2
  • H3
  • H4

Questão 19

Questão
Arrange these antihistamine medications in terms of their ability to cross the blood brain barrier, from most crossing to least.
Responda
  • Diphenhydramine, Loratidine, Fexofenadine, Cetirizine
  • Diphenhydramine, Fexofenadine, Loratidine, Cetirizine
  • Diphenhydramine, Cetirizine, Loratidine, Fexofenadine
  • Fexofenadine, Diphenhydramine, Cetirizine, Loratidine
  • Loratidine, Cetirizine, Fexofenadine, Diphenhydramine

Questão 20

Questão
Which of the following medications are First Generation Antihistamines?
Responda
  • Brompheniramine (Dimetapp)
  • Chlorpheniramine (Chlor-Trimeton)
  • Clemastine (Tavist)
  • Hydroxyzine (Atarax)
  • Levocetirizine (Xyzal)
  • Dimenhydrinate (Dramamine)
  • Diphenhydramine (Benadryl)
  • Desloratidine (Clarinex)

Questão 21

Questão
Which of the following are Second Generation Antihistamines?
Responda
  • Cetirizine (Zyrtec)
  • Desloratidine (Clarinex)
  • Diphenhydramine (Benadryl)
  • Fexofenadine (Allegra)
  • Dimenhydrinate (Dramamine)
  • Levocetirizine (Xyzal)
  • Loratidine (Claritin)

Questão 22

Questão
While antihistamines are generally used more for allergic rhinitis and congestion, one medication has some efficacy in treating cold related rhinorrhea. Which is it?
Responda
  • Cetirizine (Zyrtec)
  • Fexofenadine (Allegra)
  • Diphenhydramine (Benadryl)
  • Loratidine (Claritin)

Questão 23

Questão
What are some precautions and warnings to consider when prescribing antihistamines to patients?
Responda
  • Emphysema
  • Chronic Bronchitis
  • Narrow Angle Glaucoma
  • Cardiovascular disease
  • Enlarged Prostate Gland
  • Increased risk of CVA
  • Decrease in milk supply in nursing mothers.

Questão 24

Questão
What are some special considerations to make in elderly and children before prescribing Antihistamines?
Responda
  • Elderly patients having a paradoxical hyperactivity.
  • Children having a paradoxical hyperactivity.
  • Long half life in elderly, causing extended effect and increased fall risk.
  • Long half life in children, causing poor performance in school and social dysfunction.

Questão 25

Questão
When a combination product advertises itself as a Nighttime/PM medication, what is likely in the combination?
Responda
  • Pseudoephedrine, Phenylephrine (decongestant) but no antihistamine
  • Pseudoephedrine, Phenylephrine (decongestant) and/or an analgesic
  • Diphenhydramine, Chlorpheniramine, or Doxylamine
  • Dextromethorphan
  • Antihistamine

Questão 26

Questão
When a combination product advertises itself as a Nondrowsy/AM/Daytime medication, what is likely in the combination?
Responda
  • Diphenhydramine, Chlorpheniramine, or Doxylamine
  • Pseudoephedrine, Phenylephrine (decongestant) but no antihistamine
  • Pseudoephedrine, Phenylephrine (decongestant) and/or an analgesic
  • Dextromethorphan
  • Antihistamine

Questão 27

Questão
When a combination product advertises itself as a Sinus medication, what is likely in the combination?
Responda
  • Diphenhydramine, Chlorpheniramine, or Doxylamine
  • Pseudoephedrine, Phenylephrine (decongestant) but no antihistamine
  • Pseudoephedrine, Phenylephrine (decongestant) and/or an analgesic
  • Dextromethorphan
  • Antihistamine

Questão 28

Questão
When a combination product advertises itself as a Cough medication, what is likely in the combination?
Responda
  • Diphenhydramine, Chlorpheniramine, or Doxylamine
  • Pseudoephedrine, Phenylephrine (decongestant) but no antihistamine
  • Pseudoephedrine, Phenylephrine (decongestant) and/or an analgesic
  • Dextromethorphan
  • Antihistamine

Questão 29

Questão
When a combination product advertises itself as an Allergy medication, what is likely in the combination?
Responda
  • Diphenhydramine, Chlorpheniramine, or Doxylamine
  • Pseudoephedrine, Phenylephrine (decongestant) but no antihistamine
  • Pseudoephedrine, Phenylephrine (decongestant) and/or an analgesic
  • Dextromethorphan
  • Antihistamine

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