Questão 1
Questão
1-the following may be used to assess drug efficacy in the graded dose – response curve :
Responda
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A- slope of the curve
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B- ED50
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c- Emax
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D- A&C
Questão 2
Questão
2-atropine is used as pre-anesthetic medication due to all the following except :
Responda
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it decreases blood pressure
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it induces bronchodilatation & stimulates respiration
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it decreases vomiting
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it blocks the cardiac muscarinic receptors
Questão 3
Questão
3- the following is NOT an adverse effect of cholinomimetics :
Responda
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Bronchospasm
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Diarrhea
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Tachycardia
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aggravate peptic ulcer
Questão 4
Questão
4-treatment of atropine poisoning does not include:
Responda
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A- gastric lavage
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B- neostigmine
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C- diazepam
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D- cooling blankets
Questão 5
Questão
5-Important factor\s which may govern diffusion of drugs across cell membranes :
Questão 6
Questão
6- at the end of operation , the action of neuromuscular blocker is reversed by :
Responda
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a- atropine preceded by neostigmine
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b- neostigmine preceded by atropine
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c- atropine preceded by physostigmine
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d- physostigmine preceded by atropine
Questão 7
Questão
7-clearance is useful in calculation of :
Responda
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a-maintenance doce
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b-loading dose
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c- t 1\2
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d -a&c
Questão 8
Questão
8-Propranolol is contraindicated in all of the following cases except:
Responda
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A) Open angle glucoma
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B) Diabetes Mellitus
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C) Thyrotoxicosis
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D) Bronchial asthma
Questão 9
Questão
9-which of the following beta blockers is suitable in patient with open angle glaucoma ?
Responda
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a- betoxolol
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b- bisorolol
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c- pindolol
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propranolol
Questão 10
Questão
10- Which of the following drugs inhibit the release of NE :
Responda
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A) Guanethedine
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B) Reserpine
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C) Metyrosine
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D) Non of the above
Questão 11
Questão
11- patient with history of sulfonamide hypersesitivity , suffered head injury with brain edema , which of the following combinations is best for him ?
Responda
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a- acetazolamide & mannitol
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b- metolazone & mannitol
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c- dexamethazone & frusemide
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d- dexamethazone & mannitol
Questão 12
Questão
12- furosemide is useful for treatment of the following conditions except :
Questão 13
Questão
13-antihypertensive effect of frusemide is decreased by :
Responda
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a- NSAIDs
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b- spironolactone
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c- corticosteroids
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d- a& c
Questão 14
Questão
14-The following diuretics are secreted through the renal tubules except:
Responda
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a- Triamterene
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b- Spironolactone
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c-Hydrochlorothiazide
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d- Frusemide
Questão 15
Questão
15- uses of acetazolamide include all the following except :
Responda
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a- urinary calcium phosphate stones
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b- emphysema & high altitude sickness
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c- to alkalinize urine for excretion of salicylates
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d- to alkalinize urine for excretion of barbiturates
Questão 16
Questão
16- ACEIs have the following advantages except :
Responda
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a- they induce no change in heart rate
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b- they preserve renal function
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c- they induce no change in k level
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d- they reduce cardiovascular mortality
Questão 17
Questão
17- A nitric oxide donor that may induce cyanide toxicity :
Responda
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a- nitrates
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b- nitroprusside
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c- nicardipine
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d- A&B
Questão 18
Questão
18- A hypertensive patient with angina should not be given :
Responda
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a-pindolol
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b- bisoprolol
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c- amlodipine
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d- metoprolol
Questão 19
Questão
19- used with vasodilators to counteract the reflex tachycardia :
Responda
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a- captopril
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b- methyldopa
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c- bisoprolol
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d- pindolol
Questão 20
Questão
20- in congestive heart failure , the following drugs act directly on the myocardium increasing the cardic output except :
Responda
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a- captopril
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b- digoxin
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c- dopamine
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d- dobutamine
Questão 21
Questão
21-A drug used to terminate an attack of paroxysmal supraventricular tachycardia but may induce bronchospasm :
Responda
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a- lidocaine
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b-adenosine
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c- verapamil
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d- diltiazem
Questão 22
Questão
22- all the following decrease mortality in HF except :
Responda
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a- metoprolol
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b-bisoprolol
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c- carvedilol
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d- pindolol
Questão 23
Questão
23-A pregnant asthmatic hypertensive patient should NOT receive :
Responda
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a- candesartan
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b- labetalol
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c- thiazides
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d- all the above
Questão 24
Questão
24- In management of digitalis induced bradyarrhythmia the following is (are) true :
Responda
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a- KCL should not be administered
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b- atropine should be administered
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c- lidocaine should be administered
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d- A&B
Questão 25
Questão
25- candesartan has the following advantages over lisinopril EXCEPT :
Responda
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a- no bradykinin production thus no risk of cough
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b- antagonizes AG II formed by ACE & non- ACE pathways
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c- no hormonal "escape " seen with prolonged ACEIs therapy
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d- less teratogenic
Questão 26
Questão
26- which one of the following is adirect inhibitor of factor Xa ?
Responda
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a- dalteparin
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b- heparin
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c- rivaroxaban
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d- fondaparinux
Questão 27
Questão
27- all the following decrease the action of warfarin except :
Responda
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a- erythromycin
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b- vit K
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c- oral contraceptives
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d- rifampicin
Questão 28
Questão
28- which of the following is long acting & can be given by single I.V bolus :
Responda
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a- streptokinase
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b- tenecteplase
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c- urokinase
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d- all of the above
Questão 29
Questão
29- folic acid deficiency is associated with the use of :
Responda
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a- methotrexate
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b- trimethoprim
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c- metronidazole
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d- A&B
Questão 30
Questão
30- given that normal Hb=14gm/ dl , which of the following the following is the parentral iron dose required to correct anemia & replenish stores for a female with Hb=4 gm / dl :
Responda
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a- 100 gm
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b- 10 gm
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c- 5 gm
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d- 2.5 gm