Questão 1
Questão
In normal RBC destruction, globin is recycled and Fe is broken down
Questão 2
Questão
In Intravascular Haemolytic Anaemia, cells are lysed in the blood vessels
Questão 3
Questão
Why is Intravascular H.A so dangerous?
Responda
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Hb dimers form in the blood and block the kidneys
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R.B.C fragments block capillaries
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R.B.C's aggregate and block capillaries
Questão 4
Questão
Renal failure and Heamoglobinurea are caused by...
Responda
-
Intravascular
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Extravascular
Questão 5
Questão
What is implicated in Extravascular Haemolytic Anaemia
Responda
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The spleen
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The bone marrow
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The liver
Questão 6
Questão
In Extravascular, macrophage Fc receptors bind to the RBC's Ig's
Questão 7
Questão
Once bound, what happens to RBC's in Haemolytic Anaemia
Questão 8
Questão
If small portions of RBC membrane is removed, what happens?
Questão 9
Questão
Loss of RBC's leads to low glucose in the spleen, which leads to...
Responda
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Inc haemolysis
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Fatigue
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Inc risk of diabetes
Questão 10
Questão
Reticuloctosis- inc presence of reticulocytes
Questão 11
Questão
What causes reticulocytosis?
Responda
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The body trying to replace lost R.B.C's but can't keep up production
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The damaged R.B.Cs degenerate into reticulocytes
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The lymphocytes attack R.B.Cs, making them degenerate into reticulocytes
Questão 12
Questão
In Drug Induced Haemolytic Anaemia, what happens?
Responda
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Drug induced antibodies cross react
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Drug specific antibodies cross react
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Drugs cause R.B.C's to aggregate
Questão 13
Questão
Haemolytic Anaemias can be caused by physical stress....
Questão 14
Questão
March Haemoglobinurea is damge to RBC's in small foot bones due to prolonged marching/running
Questão 15
Questão
Infections can cause H.A by altering R.B.C morphology
Questão 16
Questão
What's the difference between Immune and Autoimmune Haemolytic Anaemia?
Questão 17
Questão
In some cases, an RBC transfusion can lead to degredation of the original RBC's
Questão 18
Questão
Name two types of Inherited Haemolytic Anaemia
Responda
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Sickel Cell Anaemia
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Thalassaemia
Questão 19
Questão
Hereditary Spherocytosis is caused by an abnormal membrane causing Spherical R.B.C's