Questão 1
Questão
Ag- Any substance that may be recognised as foreign
Questão 2
Questão
What is this, and what is it for?
Responda
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Ig G
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Ig M
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Crossing the placenta
Questão 3
Questão
What is Ig M use for?
Responda
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Crossing the placenta
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Rapid agglutination
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Bound to B cells
Questão 4
Questão
The Rhesus positive allele is...
Responda
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Dominant
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Recessive
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Co-dominant
Questão 5
Questão
Homozygous dd has the potential to produce Anti-D in what circumstances
Responda
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Illness
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Incorrect transfusion
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Pregnancy
Questão 6
Questão
Sensitisation- binding of Ig to individual blood cell
Questão 7
Questão
Agglutination is visible when
Responda
-
The Ig binds
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A lattice is formed
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The blood cells lyse
Questão 8
Questão
Which of the following RBC's contain the H substance (L-Fucose)
Questão 9
Questão
Type AB has what added to the H substance?
Responda
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N-Galactosamine
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D- Galactose
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N-Glucosamine
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Acetyl CoA
Questão 10
Questão
Which of the following is the 'Universal Receiver'?
Questão 11
Questão
How do blood grouping cards work?
Responda
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Tiny columns of small beads with Ig's bound
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If blood agglutinates due to Ig's, it cannot pass through column
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If blood agglutinates due to Ig's, it sinks to the bottom of the column
Questão 12
Questão
1 in 40 people have Ig's other than ABO and Rhesus
Questão 13
Questão
How many Ig's (other than ABO and Rhesus) can cause haemolytic reactions
Questão 14
Questão
3 Cells are brought in as controls- why?
Responda
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Between the three of them, they cover all 20 Ig's
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Then the patient plasma is added, and the reaction studied
Questão 15
Questão
If the plasma reacts to any of the 20 Ig's, what happens?
Responda
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They're tested against 10 donors (process of elimination)
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They're tested against 20 donors (process of elimination)
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They're tested against 15 donors (process of elimination)
Questão 16
Questão
Pregnant women protect their fetuses by injecting Anti-D
Questão 17
Questão
What is cross matching?
Questão 18
Questão
Transfusions are necessary if >40% of blood is lost
Questão 19
Questão
What is an Exchange Transfusion?
Questão 20
Questão
Exchange transfusion is used for babies with HDN
Questão 21
Questão
Why are antibodies the issue in blood transfusions?
Responda
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They are much more abundant than RBC's
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RBC's don't contain the MAC Class 1 marker that allows self cells to be identified
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RBC reactions can be easily stopped
Questão 22
Questão
RBC's are stored in 120-200 ml quantities
Questão 23
Questão
1 unit of RBC's is expected to raise blood Hb by how much?
Questão 24
Questão
Blood is transfused over 2-3 hours
Questão 25
Questão
1 bag of RBC's costs how much?
Questão 26
Questão
Plasma has a shelf life of _ and a half life of _ once unfrozen
Responda
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2 years
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1 year
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6 months
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4-8 hours
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2-4 hours
Questão 27
Questão
With plasma, Universal Donor's and Receivers are reversed
Questão 28
Questão
Plasma is dosed at 12-15ml/kg
Questão 29
Questão
Plasma also contains
Responda
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Clotting factors
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Ig's
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Drugs
Questão 30
Questão
A bag of plasma and clotting factors costs £40.00
Questão 31
Questão
Cryoprecipitate contains concentrated clotting factors and Ig's
Questão 32
Questão
Cryoprecipitate has a shelf life of _ at -30 degrees
Questão 33
Questão
When is cryoprecipitate added?
Questão 34
Questão
Platlets are stored at 22 degrees and cannot be refrigerated
Questão 35
Questão
Platelets have a shelf life of 7 days if...
Responda
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it's kept agitated
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it's kept frozen
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it is stored in a vacuum
Questão 36
Questão
Platelets are given over 30 mins and increase blood count by 3-4 x 10^9
Questão 37
Questão
What is Aphoresis
Questão 38
Questão
Platelets cost £20 a bag