6308561
Descrição
Quiz por Jim Shimoda, atualizado more than 1 year ago
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Criado por Jim Shimoda
mais de 8 anos atrás
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Questão 1
Questão
Congenital adrenal hyperplasia can be caused by...
Responda
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A lack of 21-Beta-Hydroxylase
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A lack of 11-alpha-hydroxylase
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A lack of both
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A lack of either
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None of the above
Questão 2
Questão
A lack of oxytocin can be caused by
Responda
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A problem with the anterior pituitary gland
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A problem with the supraoptic nucleus of the hypothalamus
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An excess of vasopressin
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Grave's disease
Questão 3
Questão
Oxytocin and vasopressin are protected from degradation by
Responda
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Antigens
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Their large size
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Amidation
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Disulfide bridges
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Both amidation and disulfide bridges
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Amidation and antigens
Questão 4
Questão
A patient presents with moon facies, abdominal striations, a hump behind the neck, and abdominal adipose tissue build up, tests demonstrate high cortisol and high ACTH levels. This patient most likely has:
Responda
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Addison's disease
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Cushing's Syndrome caused by adrenal malfunction
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Cushing's Syndrome caused by Cushing's disease
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Wollf-Chaikov disease
Questão 5
Questão
Which of these is the strongest inhibitor of ACTH production?
Responda
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High cortisol levels
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Sleep-wake transition
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High Growth Hormone levels
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Hyperthyroidism
Questão 6
Questão
A lack of Tyrosine in the thyroid would cause
Responda
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The overproduction of T4
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The underproduction of T3
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The overproduction of TBG
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The underproduction of both T3 and T4
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The underproduction of both TBG and TSH
Questão 7
Questão
Competitive inhibition of the follicular iodide pump due to excess _____________ can halt the production of ___________
Responda
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perchlorate ; thyroid hormones
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thyroid hormones ; TSH
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TSH ; thyroid hormones
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Oxytocin ; Vasopressin
Questão 8
Questão
(Choose the most accurate answer) - Synthesis of Thyroid hormones (T3 and T4) occurs....
Responda
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In the pituitary gland
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In the thyroid
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In the follicular space
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In the follicular cells
Questão 9
Questão
A patient in the first trimester of pregnancy presents with hyperthyroidism, high Thyroid hormone levels, and low TSH levels. The recommended course of treatment is
Responda
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PTU
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Methimazole
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Exogenous TSH
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Radioactive Iodine
Questão 10
Questão
Prenatal iodine deficiency causes
Responda
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Cretinism
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Overproduction of Growth Hormone
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Grave's disease
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Hashimoto's Thyroiditis
Questão 11
Questão
________ has a longer half-life in plasma
Responda
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T4
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T3
Questão 12
Questão
Conversion of T4 to T3 occurs in the:
Responda
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Thyroid
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Pituitary gland
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Peripheral tissues
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TBG
Questão 13
Questão
Choose the correct relationship between somatostatin and the hormone(s) below:
Responda
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Somatostatin inhibits TSH, Promotes GH
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Somatostatin inhibits both TSH and GH
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Somatostatin inhibits GH, has no effect on TSH
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Somatostatin promotes TSH and inhibits GH
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Somatostatin has no effect on TSH or GH
Questão 14
Questão
Thyroid hormone receptors are:
Responda
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Bound to DNA and activated when T3 binds to the receptor
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In the nucleus, are activated and bind to DNA when T3 binds the receptor
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On the membrane of cells, act via second messengers
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Deactivated by HSP90 binding, which is only removed when T3 binds the receptor
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Only activated by T4, not T3
Questão 15
Questão
Hashimoto's thyroiditis is causes
Responda
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Hyperthyroidism
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Hypothyroidism
Questão 16
Questão
Cerebral osmoreceptors in the __________ respond to changes in the blood osmolality
Responda
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Supraoptic nucleus
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OVLT and SFO
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Posterior pituitary
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Anterior pituitary
Questão 17
Questão
Plasma concentration of AVP is a function of....
Responda
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ADH concentration
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Osmotic threshold
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Oxytocin concentration
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Urine osmolality and Osmotic Threshold
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Plasma osmolality and Osmotic Threshold
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Plasma Osmolality, osmotic threshold, and BP
Questão 18
Questão
Maximum antidiuresis occurs at what concentration of AVP?
Responda
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5 pg/ml
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20 pg/ml
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5 mg/ml
Questão 19
Questão
At constant plasma osmolality, a decrease in blood pressure leads to
Responda
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An increase of AVP concentration
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An increase of oxytocin concentration
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A decrease of AVP concentration
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Both A and B
Questão 20
Questão
AVP functions by
Responda
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Increasing the number of Aquaporins in the kidney tubule lumen
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increasing Protein Kinase A activity in kidney tubule cells
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Exocytosis of AQP2 containing vesicles in kidney tubule cells
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All of the above
Questão 21
Questão
Nephrogenic diabetes insipidus is caused by:
Responda
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Lack of AVP production in the posterior pituitary
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Problems with V1a receptors in the CNS
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Problems with V2 receptors in the kidneys
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Problems with oxytocin receptors
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Placental secretion of vasopressinase
Questão 22
Questão
If excess Potassium is detected, ____________ secretion will occur
Responda
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Aldosterone
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Cortisol
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Growth Hormone
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Vasopressin
Questão 23
Questão
Steroid receptors work by
Responda
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Binding HSP90 and beginning transcription
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Binding G-proteins that have been released by membrane receptors
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Releasing HSP90 upon binding a steroid
Questão 24
Questão
What is the major dimerization partner for receptors?
Responda
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RAR
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RXR
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PPAR
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GR
Questão 25
Questão
In a Stachard plot, a hormone that binds two different receptors with different affinities makes a _________ line.
Responda
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Straight
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Curved
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It actually makes two lines
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Vetical
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Horizontal
Questão 26
Questão
On a hormone binding curve, a left-shift equals a(n) ___________
Responda
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Increase in affinity
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Decrease in affinity
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increase in plasma hormone concentration
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Decrease in plasma hormone concentration
Questão 27
Questão
In the islet of Langerhans
Responda
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Beta cells produce glucagon
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Gamma cells produce insulin
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Blood flows from the periphery to the center
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Beta cells are the most numerous
Questão 28
Questão
In the pancreas, endocrine glands secret ___________ and exocrine glands secrete ___________
Responda
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directly into an artery ; directly into a vein
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into a vein ; into the digestive system
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into the pancreatic duct ; into the venous system
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into the digestive system ; into the liver
Questão 29
Questão
The cell type(s) of the islet of langerhans that serete Ghrelin are:
Responda
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Epsilon and alpha
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Beta and alpha
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F cells
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Beta only
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epsilon only
Questão 30
Questão
Pancreatic F cells release:
Responda
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Insulin
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Glucagon
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Somatostatin
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Pancreatic polypeptide
Questão 31
Questão
Put these steps into the proper order for Insulin excretion
1) Rise in ATP
2) Opening of inflowing calcium channels
3) Entry of Glucose through the GLUT2 channel
4)Opening of Voltage gated K channel
5) Insulin secretion
Responda
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1, 5, 3, 4, 2
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3, 1, 5, 2, 4
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4, 3, 1, 2, 5
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3, 1, 4, 2, 5
Questão 32
Questão
Insulin exocytosis from Beta cells is most similar to which process:
Responda
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TBG exocytosis from the thyroid follicle cells
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Exocrine gland function of pancreas cells
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Acetylcholine exocytosis in the Neuromuscular junction
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Posterior pituitary hormone release
Questão 33
Questão
In the presence of high norepinephrine levels, the exocytosis of insulin from Beta cells is
Responda
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Increased
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Inhibited
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Unaffected
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Only affected if epinephrine is also present
Questão 34
Questão
How does amylin assist in glycemic regulation
Responda
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It doesn't
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Slows gastric emptying
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Boosts insulin levels
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Forms plaques that speed glucose uptake
Questão 35
Questão
How does caffeine effect Beta cell exhaustion
Responda
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Dude, caffeine is bad for you. Everyone knows that.
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Breaks up amyloid plaques, keeping Beta cells functional longer
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Slows insulin release, regulating Beta cell function
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Stimulates insulin release, helping relieve type 2 diabetes
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Stimulates insulin release, helping relieve type 1 diabetes
Questão 36
Questão
Over-release of growth hormone in childhood causes:
Responda
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Gigantism
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Acromegaly
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TSH release
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Glucocorticoid release
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