6812977
Questão 1
Questão
Which options are primary lymphoid organs?
Responda
-
Thymus
-
Bone marrow
-
Spleen
-
Peyer's patches
-
MALT
Questão 2
Questão
Which options are secondary lymphoid organs?
Responda
-
MALT
-
Spleen
-
Lymph nodes
-
Thymus
-
Bone marrow
Questão 3
Questão
Dendritic cells are derived from lymphoid and myeloid precursors.
Responda
- True
- False
Questão 4
Questão
Platelets are derived directly from pluripotent stem cells.
Responda
- True
- False
Questão 5
Questão
Which options do not express MHC Class 1?
Responda
-
Red blood cells
-
Platelets
-
Neutrophils
-
B cells
-
T cells
Questão 6
Questão
Naive B cells are derived from the
Responda
-
Bone marrow
-
Thymus
-
Spleen
-
MALT
Questão 7
Questão
CD4+ T cells recognise
Responda
-
MHC Class 1
-
MHC Class 2
Questão 8
Questão
CD8+ T cells recognise
Responda
-
MHC Class 1
-
MHC Class 2
Questão 9
Questão
CD16 and CD56 are both found on
Responda
-
NK cells
-
Macrophages
-
B cells
-
T cells
Questão 10
Questão
All leukocytes express
Responda
-
CD45
-
CD19
-
CD68
-
CD59
Questão 11
Questão
The most abundant leukocyte in circulation are...
Responda
-
Neutrophils
-
Macrophages
-
B cells
-
CD8+ T cells
Questão 12
Questão
Monocytes and Macrophages help to produce components involved in the complement system
Responda
- True
- False
Questão 13
Questão
Macrophages are able to present antigens on their surface
Responda
- True
- False
Questão 14
Questão
Monocytes have CD.....
Responda
-
14
-
56
-
16
-
15
Questão 15
Questão
During phagocytosis, fusion of the lysosome and phagosome leads to production of...
Responda
-
Phagolysosome
-
Early endosome
-
Endophagosome
Questão 16
Questão
Which granulocytes have major basic protein in their granules?
Responda
-
Eosinophils
-
Basophils
-
Neutrophils
Questão 17
Questão
Which granulocytes have lactoferrin in their granules?
Responda
-
Neutrophils
-
Eosinophils
-
Basophils
Questão 18
Questão
Which granulocytes do not have histamine in their granules?
Responda
-
Eosinophils
-
Neutrophils
-
Basophils
Questão 19
Questão
Which granulocytes have chondroitin sulphate in their granules?
Responda
-
Neutrophils
-
Eosinophils
-
Basophils
Questão 20
Questão
Which of these are reactive oxygen species?
Responda
-
Hypochlorous acid
-
Hydrogen peroxide
-
Superoxide
-
Water
Questão 21
Questão
The only antimicrobial peptides that macrophages use are...
Responda
-
Cathelicidins
-
Azurocidin
-
Defensins
-
Histatins
Questão 22
Questão
Acidification by neutrophils or macrophages is...
Responda
-
Bacteriocidal
-
Bacteriostatic
-
Can be both
Questão 23
Questão
Both macrophages and neutrophils produce ROS's.
Responda
- True
- False
Questão 24
Questão
Both macrophages and neutrophils produce NETs.
Responda
- True
- False
Questão 25
Questão
The most potent antigen present cell is...
Responda
-
Dendritic cells
-
Macrophages
-
Monocytes
-
B cells
Questão 26
Responda
-
platelet
-
ctivating
-
fibrinogen
-
ytokines
-
C3b
Questão 27
Questão
Most T cells are...
Responda
-
CD4 positive but CD8 negative
-
CD4 positive and CD8 positive
-
CD8 positive but CD4 negative
Questão 28
Questão
Which cytokine results in a T cell receptor being produced on an immature T cell?
Responda
-
IL-7
-
IL-10
-
GM-CSF
-
TNF-a
Questão 29
Questão
Self molecules are said to induce...
Responda
-
Tolerance
-
Multi-specificity
-
Immunogenicity
Questão 30
Questão
What is negative selection?
Responda
-
T cells with a high affinity for self antigens are killed by apoptosis
-
T cells with a high avidity for self antigens are killed by apoptosis
-
T cells with a low affinity for self antigens are killed by apoptosis
-
T cells with a low affinity for self antigens are allowed to mature
Questão 31
Questão
What is positive selection?
Responda
-
T cells with a low affinity for self antigens are allowed to mature
-
T cells with a high affinity for self antigens are allowed to mature
-
T cells with a high affinity for self antigens are killed off by apoptosis
-
T cells with a low affinity for self antigens are killed off by apoptosis
Questão 32
Questão
The majority of T cells do not make it through negative selection.
Responda
- True
- False
Questão 33
Questão
T cells without any stimulation also die off.
Responda
- True
- False
Questão 34
Questão
What CD do T regulatory cells have?
Responda
-
4
-
19
-
8
Questão 35
Questão
Which cells do TH1 helper cells activate?
Responda
-
Macrophages
-
B cells
-
Any nucleated cell
-
Stromal cells
Questão 36
Questão
Which cells do TH2 helper cells activate?
Responda
-
B cells
-
Macrophages
-
T cells
-
Stromal cells
Questão 37
Questão
Which cells do TH17 helper cells activate?
Responda
-
Stromal cells
-
B cells
-
Macrophages
-
T cells
Questão 38
Questão
What is the main effect of T reg cells?
Responda
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Questão 39
Questão
What is the main effect of TH2 cells?
Responda
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Questão 40
Questão
What is the main effect of TH1 cells?
Responda
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Questão 41
Questão
What is the main effect of TH17 cells?
Responda
-
Recruiting neutrophils
-
Activating macrophages
-
Triggering B cell proliferation and antibody secretion
-
Inhibition of immune response
Questão 42
Questão
Which cytokine(s) tend to be released by TH17 cells?
Responda
-
IL-7
-
IL-17
-
TGF-beta
-
IL-10
Questão 43
Questão
Which cytokine(s) tend to be released by TH1 cells?
Responda
-
IL-7
-
IL-10
-
IFN-gamma
-
TGF-beta
Questão 44
Questão
Which cytokine(s) tend to be released by TH2 cells?
Responda
-
IL-4
-
TNF-a
-
TNF-b
-
PGD2
Questão 45
Questão
Which cytokine(s) tend to be released by CD8+ cells?
Responda
-
IFN-gamma
-
TNF-a
-
TGF-b
-
IL-4
Questão 46
Questão
What feature on T cells helps to induce proliferation B cells?
Responda
-
CD40
-
CD40 Ligand
-
mIgM
-
CD45
Questão 47
Questão
B cells have complement receptors.
Responda
- True
- False
Questão 48
Questão
As well as perforin and granzyme to kill target cells, NK cells have...
Responda
-
NK Cytotoxic factor
-
CD40 Ligand
-
Major basic protein
-
Lyophosphatase
Questão 49
Questão
Interferon gamma is produced by NK cells - what is its function?
Responda
-
Activate phagocytes
-
Activates B cells
-
Induces proliferation of T cells
Questão 50
Questão
NK cells have a T cell receptor.
Responda
- True
- False
Questão 51
Questão
T cells are the most abundant lymphocytes.
Responda
- True
- False
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