Questão 1
Questão
[blank_start]Diabetes Mellitus (DM)[blank_end] is actually a group of metabolic disorders characterized by hyperglycemia which results from defect in secretion of insulin, action of insulin, or both
Questão 2
Questão
What counterregulatory hormones are responsible for the decrease in insulin release when blood glucose levels drop? (select all that apply)
Responda
-
Glucagon
-
growth hormone
-
glucocorticoids
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epinephrine
-
thyroid hormone
Questão 3
Questão
[blank_start]DDP-IV[blank_end] enzymes are responsible for the break down of gut incretins GLP-1 and GIP.
Questão 4
Questão
Insulin is secreted from ___________.
Responda
-
alpha cells
-
beta cells
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gamma cells
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delta cells
Questão 5
Questão
What would you check to see if a person is in fact making insulin?
Responda
-
preproinsulin
-
proinsulin
-
C peptide
Questão 6
Questão
Fill in the blanks
Responda
-
GLUT
-
potassium
-
depolarization
Questão 7
Questão
Meal ingestion causes the rapid release of insulin and [blank_start]amylin[blank_end] from the pancreas.
Responda
-
amylin
-
proinsulin
-
c peptide
Questão 8
Questão
Type 1 DM is the abosulte deficiecny of amylin and insuilin.
Questão 9
Questão
Which of the following is NOT an effect of amylin?
Questão 10
Questão
In glucose homeostasis, 40% of gluconeogeneiss occurs in the [blank_start]kidneys[blank_end] and reabsoprtion of glucose occurs in the [blank_start]proximal tubule[blank_end].
Questão 11
Questão
Fill in the blanks with appropriate values used to diagnose a patient with PRE-DIABETES according to ADA guidelines?
FPG/IFG: [blank_start]100-125mg/dL[blank_end]
2-hr OGTT/IGT: [blank_start]140-199mg/dL[blank_end]
A1c: [blank_start]5.7% - 6.4%[blank_end]
Responda
-
50-100mg/dL
-
100-125mg/dL
-
150-200mg/dL
-
200-225mg/dL
-
100-125mg/dL
-
140-199mg/dL
-
220=250mg/dL
-
5.7% - 6.4%
-
7% -7.5%
-
8% - 8.5%
Questão 12
Questão
β-cell destruction usually leading to absolute insulin and amylin deficiency.
Questão 13
Questão
“Progressive insulin secretory defect (β-cell dysfunction) on the background of insulin resistance.
Responda
-
Type 1 DM
-
Type 2 DM
-
Gestational DM
Questão 14
Questão
Diabetes diagnosed during pregnancy that IS NOT clearly overt diabetes
Responda
-
Type 1 DM
-
Type 2 DM
-
Gestational Diabetes
Questão 15
Questão
Fill in the table below
Questão 16
Questão
Which of the following below are symptoms of HYPERglycemia? (select all that apply)
Responda
-
polydipsia
-
polyuria
-
polyphagia
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dry skin
-
blurry vision
-
drowsy
-
slow healing wounds
Questão 17
Questão
During pregnanacy, the placenta can produce hormones that contribute to insulin resistance.
Questão 18
Questão
Criteria for the diagnosis of diabetes;
(1) A1C > [blank_start]6.5[blank_end]%
(2) FPG > [blank_start]126[blank_end] mg/dL
(3) 2-hr PG > [blank_start]200[blank_end] mg/dL after a 75 gram oral glucose tolerance test (OGTT)
Questão 19
Questão
Acanthosis Nigricans is associated with ....
Questão 20
Questão
Children with BMI precentile of [blank_start]85[blank_end] or greater should be considered for screening for T2DM
Questão 21
Questão
When should pregnant women without overt DM should be screeened for gestational diabetes mellitus?
Responda
-
15-20 weeeks
-
20-22 weeks
-
24-28 weeks
-
30-33 weeks
Questão 22
Questão
Gestational diabetes mellitus should be tested for a second time 2-3 weeks post partum.
Questão 23
Questão
Which of the following are complications of DM in pregnancy (select all that apply)
Responda
-
gestational HTN
-
Preecalmpsia
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Gestational HYPOtension
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infections
-
ketoacidosis
-
polyhrdramnios
-
preterm labor
-
seizures
Questão 24
Questão
Fill in the appropriate values for the ACOG: Carpenter and Coustan 100mg OGTT 3hr (mg/dL) which is used in the diagnosis of GDM.
Fasting: [blank_start]95[blank_end]
1 hour: [blank_start]180[blank_end]
2 hours: [blank_start]155[blank_end]
3 hours: [blank_start]140[blank_end]
Questão 25
Questão
What are the glycemic goal for patients with GDM and preexisting DM?
(1) Fasting less than or equal to [blank_start]95[blank_end] mg/dL
(2) 1-hr PP less than or equal to [blank_start]140[blank_end] mg/dL
(3) 2-hr PP less than or equal to [blank_start]120[blank_end] mg/dL
Questão 26
Questão
During pregnancy an A1C of [blank_start]6-6.5[blank_end] % is the reccomeneded target in the second and third trimester but < [blank_start]6[blank_end] % may be optimal.
Questão 27
Questão
During pregnancy insulin resistance decreases as pregnancy progresses
Questão 28
Questão
Hypoglycemia is usually defined as < 70 mg/dl but in pregnancy BG is often allowed to be than [blank_start]60[blank_end] mg/dL
Questão 29
Questão
Indicate which insulins and oral medications are utilized in the treatment of diabetes during pregnancy?
Responda
-
Metformin
-
Lantus
-
Glargine
-
NPH
-
Regular insulin
-
Glyburide
-
Apidra
Questão 30
Questão
[blank_start]Insulin[blank_end] is the first-line agent recommended for treatment of GDM in the U.S
Questão 31
Questão
[blank_start]Glyburide[blank_end] may be inferior to metformin and insulin due to increased risk of neonatal hypoglycemia and macrosomia
Questão 32
Questão
[blank_start]Aspart[blank_end] and [blank_start]Lispro[blank_end] are the only rapid-acting insulins approved during pregnancy
Questão 33
Questão
[blank_start]Detemir[blank_end] is the only long-acting basal insulin utilized to treat diabetes in pregnancy
Questão 34
Questão
What are the glucose levels for insulin initiation in GDM
Fasting PG less than or equal to [blank_start]105[blank_end] mg/dL
1-hours postprandial plasma glucose less than or equal to [blank_start]155[blank_end] mg/dL
2-hour postprandial plasma glucose less than or equal to [blank_start]130[blank_end] mg/dL
Questão 35
Questão
T1DM will require insulin during labor while most do not require insulin during labor and delivery with GDM
Questão 36
Questão
What immunizations are reccomended for diabetic patients?
Responda
-
influnenza
-
pneumococal
-
hepatitis B
Questão 37
Questão
Hypoglycemia is indicated with a BG of less than [blank_start]70[blank_end] mg/dL
Questão 38
Questão
1) If blood glucose (BG) is less than 70 mg/dL, you should give [blank_start]15[blank_end] grams of carbs and recheck the blood glucose after 15 minutes.
2) If blood glucose is less than 50 mg/dL , you should give [blank_start]30[blank_end] grams of carbs and recheck the blood glucose after 15 minutes
Questão 39
Questão
15g is equal to:
[blank_start]1[blank_end] tablespoon of sugar, [blank_start]3-4[blank_end] hard candies, [blank_start]4[blank_end] oz regular fruit juice, [blank_start]6[blank_end] oz regular soda, 3-4 glucose tablets, 6 lifesvavers save a life
Responda
-
1
-
3-4
-
4
-
6
-
3-4
-
1
-
4
-
6
-
4
-
1
-
3-4
-
6
-
6
-
4
-
1
-
3-4
Questão 40
Questão
Which of the following should be part of the sick day management plan?
Responda
-
Check BG more frequently
-
Try to keep BG < 200 mg
-
Contiune basal insulin
-
Stay hydrated
-
use liquid carbohydrates to keep BG stable if unable to keep food down or having frequent or severe drops in BG
-
May need to hold prandial insulin or some oral medications if unable to keep down any carbohydrates.
Questão 41
Questão
What are the possible causes of DKA?
Responda
-
Exacerbated by an increase in counterregulatory hormones – hyperglycemic crisis
-
Insulin deficiency promotes lipolysis and metabolism of FFA to β-hydroxybutyrate, acetoacetic acid, and acetone in the liver
-
Excess glucagon enhance gluconeogenesis and impairs peripheral ketone utilization
-
Reduction in the effective circulating insulin with a concomitant elevation of counter-regulatory hormones
Questão 42
Questão
What are the causes of HHS?
Responda
-
Excess glucagon enhance gluconeogenesis and impairs peripheral ketone utilization
-
Reduction in the effective circulating insulin with a concomitant elevation of counter-regulatory hormones
-
Consistently elevated blood glucose concentration (sometimes weeks) in the face of reduce fluid intake
-
Most commonly preceded by infection or other serious illness
Questão 43
Questão
Complete the algorithhm
Responda
-
0.9% NaCl
-
0.45% NaCl
-
0.9% NaCl
-
200
-
300
-
0.1
-
0.14
-
0.14
Questão 44
Questão
Complete the algortithm
Questão 45
Questão
In hospital care, treat if the blood glucose is above [blank_start]180[blank_end] mg/dL with a goal between [blank_start]140-180[blank_end] mg/dL.
Questão 46
Questão
In what conditions should you consider lowering the dose of basal insulin by 20%?
Questão 47
Questão
Turn off insulin infusion [blank_start]2[blank_end] hours after administration of SubQ basal insulin
Questão 48
Questão
Fill in the Tabel below
Responda
-
Type 1
-
Type 2
-
Hours to days
-
Days to weeks
-
> 250
-
>600
-
< 7.35
-
7.35-7.45
-
Present
-
Absent or very little
-
< 320
-
> 320
-
Type 2
-
Type 1
-
Hours to days
-
Days to weeks
-
> 250
-
> 600
-
< 7.35
-
7.35 - 7.45
-
Present
-
Absent or very little
-
< 320
-
> 320