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Pregnancy and Lactation

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NAPLEX Pharmacy (Endo) Quiz sobre Pregnancy and Lactation, criado por Mark W. em 14-12-2016.
Mark W.
Quiz por Mark W., atualizado more than 1 year ago
Mark W.
Criado por Mark W. mais de 7 anos atrás
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Resumo de Recurso

Questão 1

Questão
How many weeks constitute a term pregnancy?
Responda
  • 24-30 weeks
  • 30-35 weeks
  • 37-42 weeks
  • 44-46 weeks

Questão 2

Questão
Fill the table below with the appropriate Physiologic/Pharmacokinetic changes
Image:
080fa2c6-31ed-40ce-b475-aaf6aa9ce348 (image/png)
Responda
  • increase in hepatic metabolism
  • decrease in hepatic metabolism
  • thinning of barrier
  • thickening of barrier
  • increased renal blood flow
  • decreased renal blood flow
  • increased blood volume
  • decreased blood volume
  • increased albumin concentration
  • decreased albumin concentration
  • decrease motility
  • increased motility
  • increased intestinal blood flow
  • decreased intestinal blood flow
  • increased gastric pH
  • decreased gastric pH
  • increase metabolism
  • decreased metabolism
  • increased distribution
  • decreased distribution
  • increased GFR
  • decreased GFR
  • increased elimination
  • decreased elimination
  • increased distribution
  • decreased distribution
  • increased protein binding
  • decreased protein binding
  • increased absorption
  • decreased absorption
  • increased concentration
  • decreased concentration
  • increased maternal concentration
  • decreased maternal concentration
  • increased fetal concentration
  • decreased fetal concentration
  • increased concentration
  • decreased concentration
  • increase concentration
  • decrease concentration
  • increased free drug concentration
  • decreased free drug concentration
  • increased concentration
  • decreased concentration

Questão 3

Questão
Which of the following are true in regards to medication use in pregnancy? (select all that apply)
Responda
  • eliminate nonessential drugs
  • discourage self-medication
  • minimize exposure to harmful medications
  • adjust doses for use during pregnancy

Questão 4

Questão
What vaccinations should be administered during pregnancy?
Responda
  • Inactivated influenza vaccine
  • Tdap ( @ 27-36 weeks)
  • Hepatitis B
  • Hepatitis A
  • Meningitis

Questão 5

Questão
Why are multivitamins used during pregnancy?
Responda
  • fetal bone development
  • maternal and fetal erythropoiesis
  • prevent neural tube defect

Questão 6

Questão
Why is calcium used during pregnancy?
Responda
  • maternal and fetal erythropoiesis
  • fetal bone development
  • prevent neural tube defect
  • prevention of HTN

Questão 7

Questão
[blank_start]Folic acid[blank_end] is used during pregnancy to prevent neural tube defects
Responda
  • Folic acid

Questão 8

Questão
Drugs with a molecular weight of less than [blank_start]600[blank_end] daltons readily cross the placenta barrier.
Responda
  • 600

Questão 9

Questão
Lipophilic drugs will cross the placental barrier more than hydrophilic drugs
Responda
  • True
  • False

Questão 10

Questão
Which albumin levels are higher, fetal or maternal?
Responda
  • fetal
  • maternal

Questão 11

Questão
Fetal blood pH < maternal, therefore weak bases more easily cross, ionize, and less likely to diffuse back across the placental barrier
Responda
  • True
  • False

Questão 12

Questão
Only [blank_start]unbound[blank_end] drugs can cross placental membranes
Responda
  • unbound

Questão 13

Questão
Blood flow to [blank_start]uterus[blank_end] impacts drug transfer to fetus
Responda
  • uterus

Questão 14

Questão
What is the drug of choice for the treatment of hyperemesis gravidarum?
Responda
  • ondansetron
  • pyridoxine
  • doxylamine
  • phosphoric acid

Questão 15

Questão
The treatment of choice for nausea and vomiting during pregnancy is [blank_start]nonpharmacological treatment[blank_end]
Responda
  • nonpharmacological treatment
  • pyridoximine and doxylamine
  • emetrol

Questão 16

Questão
What is the first line or drug of choice for nausea and vomiting during pregnancy?
Responda
  • pyridoxine
  • doxylamine
  • phosphoric acid
  • metoclopramide

Questão 17

Questão
For nausea and vomiting during pregnancy, [blank_start]phosphoric acid[blank_end] should not be used if the patient is a diabetic
Responda
  • phosphoric acid
  • metoclopramide
  • dopamine
  • diclegis

Questão 18

Questão
Nausea and Vomiting 2nd line therapy is [blank_start]metoclopramide[blank_end] 3rd line therapy is [blank_start]dopamine antagonist[blank_end]
Responda
  • metoclopramide
  • ondansetron
  • doxylamine
  • promethazine
  • dopamine antagonist
  • dicelgis
  • ondansetron
  • methylprednisone

Questão 19

Questão
First line line treatment for constipation during pregnancy is incerase [blank_start]fiber[blank_end] and [blank_start]fluid[blank_end] intake
Responda
  • fiber
  • fluid

Questão 20

Questão
What drugs should not be used to treat constipation during pregnancy?
Responda
  • osmotic laxatives
  • docusate
  • castor oil
  • mineral oil
  • senna
  • bsicodyl

Questão 21

Questão
GERD/Heartburn 1st line: [blank_start]Lifestyle Modifications[blank_end] 2nd line: [blank_start]antacids or sucralfate[blank_end]
Responda
  • Lifestyle Modifications
  • antacids or sucralfate
  • metoclopramide
  • PPIs
  • antacids or sucralfate
  • sodium bicarbonate
  • Ranitidine
  • PPIs

Questão 22

Questão
Which of the following treatment can be used to treat Hemorrhoids during a pregnancy?
Responda
  • Higher fiber intake
  • increase oral fluid intake
  • use sitz baths
  • Topical anesthetics, protectants, and astringents
  • tylenol

Questão 23

Questão
Bulk forming agents should be utilized to treat diarrhea during pregnancy, what drugs should be avoided?
Responda
  • Diphenoxylate/atropine
  • paregoric
  • bismuth subsalicylate
  • psyllium/fiber

Questão 24

Questão
Saline nasal spray/drops are safe to use during pregnancy in the treatment of cough, colds, and allergies
Responda
  • True
  • False

Questão 25

Questão
What is the drug of choice to treat cold , cough, and allergies during pregnancy?
Responda
  • chlorpheniramine
  • diphenhydramine
  • loratidine
  • budesonide

Questão 26

Questão
What drugs are recommended during the 2nd and 3rd trimesters in the treatment of cough, cold, and allergies during pregnancy?
Responda
  • diphenhydramine
  • loratidine
  • cetirizine
  • beclomethasone

Questão 27

Questão
What nasal steroids are recommended for chronic allergies during pregnancy?
Responda
  • Budesonide (Rhinocort)
  • Beclomethasone (Beconase AQ)
  • Advair

Questão 28

Questão
[blank_start]Acetaminophen[blank_end] is the drug of choice for acute pain managment during pregnancy
Responda
  • Acetaminophen
  • opioids
  • NSAIDs
  • aspirin

Questão 29

Questão
What is the drug of choice in the treatment of HTN and severe eclampsia?
Responda
  • labetalol
  • hydralazine
  • IV magnesium

Questão 30

Questão
IV [blank_start]Magnesium[blank_end] is used for seizure protection and treatment
Responda
  • Magnesium

Questão 31

Questão
Pharmacological treatment for gestational HTN should be started if the systolic BP is greater than [blank_start]150-160[blank_end] OR the diastolic is greater than [blank_start]100-110[blank_end]
Responda
  • 150-160
  • 100-110

Questão 32

Questão
Essential/Gestational HTN 1st line (DOC): [blank_start]Methyldopa[blank_end] 2nd line: [blank_start]Labetolol[blank_end]
Responda
  • Methyldopa
  • Labetalol

Questão 33

Questão
Coagulation Disorders You need to continue treatment for women with history of Deep Vein Thrombosis/Pulmonary Embolism, Mitral Valve Replacement, clotting factor deficiencies, antiphospholipid antibodies
Responda
  • True
  • False

Questão 34

Questão
Coagulation Disorders 1st line: [blank_start]LMWH[blank_end] 2nd line: [blank_start]UFH[blank_end] Treatment is to be contiuned through pregnancy and [blank_start]6[blank_end] weeks after delivery (including breastfeeding)
Responda
  • LMWH
  • UFH
  • 6

Questão 35

Questão
Which of the following drugs are contraindicated in the treatment of UTIs during pregnancy?
Responda
  • Cephalexin
  • Ampicillin
  • SMX-TMP
  • Fluoroquinolines
  • Tetracyclines

Questão 36

Questão
What are the top drug choices in the treatment of UTIs during pregnancy?
Responda
  • Cephalexin
  • Ampicillin
  • Nitrofurantoin
  • Tetracyclines

Questão 37

Questão
What drugs are utilized in the treatment of pyelonephritis?
Responda
  • Ceftriaxone
  • Ampicillin plus gentamicin
  • Ampicillin-sulbactam
  • nitrofurantoin
  • cephalexin

Questão 38

Questão
STI's Drug of choice syphillis: [blank_start]penicillin G[blank_end] Drug of choice for gonorrhea: [blank_start]cetriaxone[blank_end] Durg of choice for chlamydia: [blank_start]amoxicillin[blank_end] ; 2nd line: [blank_start]ertthromycin[blank_end]
Responda
  • penicillin G
  • ceftriaxone
  • amoxicillin
  • erythromycin
  • ceftriaxone
  • penicillin G
  • amoxicillin
  • erythromycin
  • amoxicillin
  • ceftriaxone
  • penicillin G
  • erythromycin
  • erythromycin
  • amoxicillin
  • ceftriaxone
  • penicillin G

Questão 39

Questão
Acyclovir/valacyclovir is used in the treatment of genital herpes during pregnancy
Responda
  • True
  • False

Questão 40

Questão
[blank_start]Metronidazole[blank_end] is the treatment of choice for bacterial vaginosis, and the alternative treatment is clindaymcin
Responda
  • Metronidazole

Questão 41

Questão
Asthma [blank_start]Albuterol[blank_end] is the short acting beta agonist of choice and [blank_start]budesonide[blank_end] is the inhaled corticosteriod of choice during preganancy
Responda
  • Albuterol
  • budesonide

Questão 42

Questão
During pregnancy, changing agents to minimize risk is NOT recommended for the treatment of epilepsy
Responda
  • True
  • False

Questão 43

Questão
What drugs are the safest to use to treat epilepsy during pregnancy?
Responda
  • lamotrigine
  • levetiracetam
  • valproic acid
  • carbamazepine

Questão 44

Questão
HIV during pregnancy New diagnosed: [blank_start]HAART[blank_end] [blank_start]Zidovudine[blank_end] is the mainstay of antiretroviral therapy Avoid [blank_start]efavirenz[blank_end]
Responda
  • HAART
  • Zidovudine
  • efavirenz
  • clindamycin
  • Zidovudine
  • HAART
  • efavirenz
  • clindamycin
  • efavirenz
  • Zidovudine
  • HAART
  • clindamycin

Questão 45

Questão
Treatment of schizophrenia, bipolar disorder, depression usually needs to be continued during pregnancy and breastfeeding; high relapse rates if discontinued
Responda
  • True
  • False

Questão 46

Questão
What are the most preferred agents in the treatment of mental health issues in pregnant women?
Responda
  • fluoxetine
  • citalopram
  • escitalopram
  • levetiracetam

Questão 47

Questão
Nortriptyline and desipramine are TCAs of choice in the treatment of mental health issues during pregnancy
Responda
  • True
  • False

Questão 48

Questão
Treatment of choice for HYPOthryoridism: [blank_start]levothyroxine[blank_end] Treatment of choice for HYPERthryroidism: [blank_start]propylthiouracil[blank_end] or [blank_start]methimazole[blank_end]
Responda
  • levothyroxine
  • propylthiouracil
  • methimazole

Questão 49

Questão
[blank_start]Tocolysis[blank_end] is the prcoess of stopping contractions
Responda
  • Tocolysis

Questão 50

Questão
What drugs are utilized in pre-term labor and tocolysis?
Responda
  • IV magnesium
  • terbutaline
  • nifedipine
  • promethazine

Questão 51

Questão
What drugs are needed for cervical ripening? Cervical ripening: in order to dilate, collagen must loosen and separate; moisture necessary; occurs naturally in women who spontaneously enter labor
Responda
  • misoprostol
  • dinoprostone
  • oxytocin
  • methylergonovine

Questão 52

Questão
Labor induction 1st line: [blank_start]oxytocin[blank_end] 2nd line: [blank_start]methylergonovine[blank_end]
Responda
  • oxytocin
  • Methylergonovine
  • misoprostol
  • dinoprostone
  • methylergonovine
  • dinoprostone
  • misoprostol
  • Oxytocin

Questão 53

Questão
If mother colonized with Group B Streptococcus: [blank_start]Penicillin G[blank_end]
Responda
  • Penicillin G

Questão 54

Questão
Analgesia can prolong the 1st and 2nd stages of labor
Responda
  • True
  • False

Questão 55

Questão
[blank_start]Epidural[blank_end] analgesia has better profile than parenteral opioids (poor maternal pain relief and less vigorous neonates)
Responda
  • Epidural

Questão 56

Questão
Drug Factors General Guidelines Most drugs appear in breast milk to some degree. Most common mechanism of transfer is passive diffusion. Levels of most drugs in breast milk do not usually exceed 1% to 2% of ingested maternal dosage If the milk/plasma ratio of drug and active metabolites is less than [blank_start]1:1[blank_end], it is usually safe to breastfeed RID: If infant dose is less than [blank_start]10[blank_end]% of maternal dose (weight adjusted), it is usually safe to breastfeed
Responda
  • 1:1
  • 10

Questão 57

Questão
Depression Sertraline and paroxetine are most frequently prescribed with few reported adverse effects,
Responda
  • True
  • False

Questão 58

Questão
breast milk is more acidic; weak bases are more likely to stay trapped in breast milk “ion trapping:
Responda
  • True
  • False

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