Neurodeg5HD

Description

Biologie Quiz on Neurodeg5HD, created by Mak Sch on 01/12/2017.
Mak Sch
Quiz by Mak Sch, updated more than 1 year ago
Mak Sch
Created by Mak Sch almost 7 years ago
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Resource summary

Question 1

Question
Main clinical cognitive features of Huntington’s disease include the following except:
Answer
  • B. Memory difficulties
  • A. Mental slowing
  • C. Language severe problems
  • D. Language well preserved

Question 2

Question
Question 2 Characteristics in Early stages of Huntington’s disease: (multiple answers possible)
Answer
  • A. Chorea
  • B. Agitated /mood swings
  • C. Distractable
  • D. Demented

Question 3

Question
Characteristics in Late stages of Huntington’s disease except: (multiple answers possible)
Answer
  • B. Dystonia/bradykinetic
  • C. Mood swings
  • D. Demented
  • A. Abulic

Question 4

Question
Question 7 The gene related to Huntington’s disease is Huntingtin (htt) and in order to become pathogenic it should have:
Answer
  • B. >36 insertions
  • C. >36 deletions
  • D. >36 GAC repeats
  • A. >36 CAG repeats

Question 5

Question
Main clinical psychiatric features of Huntington’s disease include: (multiple answers possible)
Answer
  • A. Irritability
  • B. Stable mood
  • D. Compulsive behaviour
  • C. Social withdrawal

Question 6

Question
The brain structures which are mainly affected by Huntington’s disease are: (multiple answers possible)
Answer
  • A. Sustantia Nigra
  • B. Cerebral cortex
  • C. Hippocampus
  • D. Striatum

Question 7

Question
Main clinical motor features of Huntington’s disease include: (multiple answers possible)
Answer
  • A. Chorea
  • B. Evolution from hyperkinetic to hypokinetic
  • C. Evolution from hypokinetic to hyperkinetic
  • D. Gait abnormalities

Question 8

Question
Question 8 Other features frequently found in patients with Huntington’s disease are the following except:
Answer
  • A. Metabolic abnormalities
  • B. Weight gain
  • C. Circadian rhythm disturbances
  • D. Autonomic abnormalities

Question 9

Question
Question 9 Huntington’s disease is an inherited disorder, it is a _____ condition.
Answer
  • Aut Dom
  • Aut Rec
  • X Dom
  • X Rec

Question 10

Question
Question 10 Mutated Huntingtin lead to: (multiple answers possible)
Answer
  • A. Transcription interference
  • B. Formation of inclusions
  • C. Cellular dysfunction
  • D. Cell death

Question 11

Question
The gene defect Huntington’s disease is known to be on Chromosome
Answer
  • 2
  • 4
  • 9
  • 11
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