Question 1
Question
What is characteristic of the Paget's disease?
Answer
-
increased osteoblast and osteoclast activity
-
"bone pain" generally in one area, commonly pelvis and spine
-
structurally disorganized bone matrix with both excessive bone mass and bone resorption
-
increased osteoblast but decreased osteoclast activity
-
uniform concentric rings of organized bone matrix
-
"bone pain" spreading out to different areas of the body
Question 2
Question
Osteoblasts mature into these cells [blank_start]osteocytes[blank_end] once trapped in the bone matrix; they activate bone formation via [blank_start]altered signalling[blank_end] and apoptosis.
Answer
-
osteocytes
-
altered signalling
Question 3
Question
What do osteoblasts do?
Question 4
Question
What is characteristic of osteoclasts?
Question 5
Question
Where would you have the most interstitial growth?
Answer
-
epiphysis
-
metaphysis
-
diaphysis
-
epiphyseal growth plates
-
periosteum
Question 6
Question
[blank_start]Interstitial[blank_end] growth is [blank_start]lengthening[blank_end] growth. This is due to increased number of matrix-depositing cells. [blank_start]Appositional[blank_end] growth is [blank_start]widening[blank_end] growth. This is due to increased matrix deposition by the same number cells.
Answer
-
Interstitial
-
Appositional
-
widening
-
lengthening
Question 7
Question
In terms of calcium metabolism, the thyroid releases what hormone?
Question 8
Question
Calcitonin causes increased calcium deposition in bone by inhibiting bone resorption.
Question 9
Question
What does parathyroid hormone do?
Answer
-
increase osteoclast activity
-
increase osteoblast activity
-
increase osteocyte activity
-
decrease osteoclast activity
-
decrease osteoblast activity
-
decrease osteocyte activity
Question 10
Question
Falling onto an outstretched hand/wrist causes what type of fracture most commonly?
Answer
-
scaphoid fracture
-
radial styloid fracture
-
humeral fracture
-
3rd metacarpal fracture
-
ulnar styloid process
-
lunate fracture
Question 11
Question
What are bones of the hand?
Answer
-
scaphoid
-
lunate
-
triquetrum
-
pisiform
-
trapezium
-
trapezoid
-
capitate
-
hamate
Question 12
Question
What nerve would you damage if you were to break the shaft of the humerus?
Answer
-
radial
-
axillary
-
musculocutaneous
-
medial
-
ulnar
Question 13
Question
If the radial nerve is damaged, how might it present?
Answer
-
wrist drop even with fully extended forearm/arm
-
inability to abduct arm
-
inability to flex elbow
-
inability to flex shoulder
-
Benedict claw with fully extended forearm/arm
Question 14
Question
What does the musculocutaneous innervate muscle-wise?
Answer
-
flexor muscles of the arm
-
flexor muscles of the forearm
-
extensor muscles of the arm
-
extensor muscles of the forearm
-
3.5 fingers of the hand
Question 15
Question
What does the axillary innervate muscle-wise?
Answer
-
deltoid, teres minor (shoulder muscles)
-
posterior arm flexor muscles
-
posterior forearm extensor muscles
Question 16
Question
What does the radial nerve NOT innervate muscle-wise?
Question 17
Question
What does musculocutaneous innervate muscle-wise?
Question 18
Question
What does ulnar nerve innervate muscle-wise?
Answer
-
posterior forearm muscles
-
posterior arm muscles
-
anterior forearm muscles
-
anterior arm muscles
-
anterior medial 2 fingers
-
posterior lateral 2 fingers
Question 19
Question
If there is loss of elbow flexion (can't flex biceps), there is damage to the [blank_start]musculocutaneous[blank_end] nerve.
Question 20
Question
if there is shoulder weakness or you're unable to abduct shoulder, then there is damage to the [blank_start]axillary[blank_end] nerve.
Question 21
Question
A hand of benediction is sign of damage to the [blank_start]median[blank_end] nerve.
Question 22
Question
Being unable to abduct or adduct the last 2 fingers is indicative of damage to the [blank_start]ulnar[blank_end] nerve.
Question 23
Question
What does the ulnar provide sensory innervation to?
Question 24
Question
What does the median provide sensory innervation to?
Answer
-
anterior 3.5 lateral fingers
-
posterior 3.5 lateral fingers
-
anterior 1.5 lateral fingers
-
posterior 1.5 lateral fingers
Question 25
Question
What does radial nerve provide sensory innervation to?
Answer
-
lateral arm
-
posterior forearm
-
posterior hand
-
anterior hand
-
anterior forearm
-
medial arm
Question 26
Question
The axillary nerve innervates the...in sensory wise
Question 27
Question
Musculocutaneous provides sensory innervation to lateral forearm down to the thenar prominence (at the base of the thumb.)
Question 28
Question
Numbness at the back of the wrist and hand is due to damage to the sensory innervation by the [blank_start]radial[blank_end] nerve.
Question 29
Question
Damage to the [blank_start]median[blank_end] nerve will lead to parethesia to the lateral 3 anterior fingers.
Question 30
Question
Loss of sensation in the median of the hand and the medial first 2 fingers is damage to the [blank_start]ulnar[blank_end] nerve.
Question 31
Question
Damage to the radial nerve leads to wrist drop. What are some pathologies in which the radial nerve gets hurt?
Question 32
Question
How might you injure the axillary nerve?
Answer
-
dislocation of the humeral head
-
surgical neck of the humerus fracture
-
dislocation of the clavicle
-
pulling the deltoid muscle
Question 33
Question
You might harm the musculocutaneous nerve via a medial epicondyle fracture.
Question 34
Question
A winged scapula is indicative of damage to the [blank_start]long thoracic nerve[blank_end] (spinal roots C5-C7.)
Question 35
Question
The spinal roots of the musculocutaneous nerve are (in numerical order from least to greatest) are [blank_start]C5[blank_end], [blank_start]C6[blank_end], and [blank_start]C7[blank_end].
Question 36
Question
The Axillary nerve is from the roots [blank_start]C5[blank_end] and [blank_start]C6[blank_end] (in numerical order.)
Question 37
Question
The radial nerve is from the spinal roots [blank_start]C5[blank_end] to [blank_start]T1[blank_end].
Question 38
Question
The ulnar nerve is from the spinal roots of [blank_start]C8[blank_end] and [blank_start]T1[blank_end].
Question 39
Question
The spinal roots of the median nerve is [blank_start]C5[blank_end] or [blank_start]C6[blank_end] to [blank_start]T1[blank_end].
Question 40
Question
Which of these myotomes and action pairings are correct?
Answer
-
C4: shoulder elevation
-
C5: chicken abduction (wings)
-
C6: elbow flexion
-
C6: wrist extension
-
C7: elbow extension
-
C7: wrist flexion
-
C8: thumb extension (thumbs up)
-
T1: finger abduction (fanned fingers)
-
C6: wrist flexion
-
C6: elbow extension
Question 41
Question
What is true regarding Erb's palsy?
Answer
-
damage to the upper part of the brachial plexus (C5 and C6)
-
damage to the lower part of the brachial plexus (C7 C8 and T1)
-
motorbike accidents can cause this
-
improper birthing techniques (pull baby's head against pelvic bones while labor) can cause this
-
landing on an outstretched arm from a big height can cause this
-
results in a "waiter's tip"
-
results in a "clawed hand"
-
damage to the axillary nerve
-
damage to the suprascapular nerve
-
damage to the musculocutaneous nerve
Question 42
Question
What is the myasthenia gravis?
Answer
-
At the neuromuscular junction, the body produces antibodies against the acetylcholine receptors
-
Intense morning sickness that needs anti-emetics as treatment
-
the gradual degradation of muscle fibers, starting from top of the head to bottom of the feet
-
loss of sensation in some or all motor units of certain muscles
Question 43
Question
How might myasthenia gravis present?
Question 44
Question
How would you manage myasthenia gravis?
Answer
-
acetylcholine esterase inhibitors
-
acetylcholine reuptake enhancers
-
acetylcholine esterase activators
-
acetylcholine agonists
Question 45
Question
The [blank_start]abdominal aorta[blank_end] bifurcates into the [blank_start]right common illiac[blank_end] and the [blank_start]left common illiac[blank_end]. The right illiac again bifurcates into the [blank_start]internal illiac[blank_end] and the [blank_start]external illiac[blank_end]. The external illiac becomes the [blank_start]right femoral[blank_end], which is the deep artery of the right thigh. In the popliteal fossa, the right femoral becomes the right [blank_start]popliteal[blank_end] artery. The right popliteal further bifurcates into the [blank_start]right anterior tibial[blank_end] and the [blank_start]right posterior tibial.[blank_end] The right posterior tibial, which is the pulse felt at the ankle, becomes the [blank_start]posterior right fibular.[blank_end] The right anterior tibial becomes the right [blank_start]dorsalis pedalis[blank_end].
Question 46
Question
Which of the following could cause carpal tunnel syndrome?
Answer
-
pregnancy
-
rheumatoid arthiritis
-
repetitive use of hands
-
septic arhritis
-
osteomalacia
-
osteoporosis
Question 47
Question
Compression of the [blank_start]median[blank_end] nerve as it travels through the [blank_start]carpal[blank_end] [blank_start]tunnel[blank_end] in the wrist is Carpal Tunnel Syndrome.
Question 48
Question
How does Carpal Tunnel Syndrome present?
Question 49
Question
What are management options of the carpal tunnel syndrome?
Answer
-
local corticosteroids
-
night time splinting
-
day time splinting
-
anabolic steroids
-
always surgical decompression
-
if severe surgical decompression
-
avoid further injury via strain
Question 50
Question
What are the nerves of the lower limb?
Question 51
Question
The [blank_start]sural[blank_end] nerve only innervates sensory-wise. It innervates the skin of the [blank_start]posterior[blank_end] leg and [blank_start]lateral[blank_end] foot.
Question 52
Question
What does the sciatic innervate muscle-wise?
Answer
-
the posterior compartment of the thigh
-
the anterior compartment of the thigh
-
lateral compartment of the thigh
-
the medial compartment of the thigh
Question 53
Question
What does the femoral nerve innervate muscle-wise?
Answer
-
anterior thigh
-
posterior thigh
-
lateral thigh
-
medial thigh
Question 54
Question
What does the obturator nerve innervate muscle wise?
Answer
-
anterior thigh
-
posterior thigh
-
lateral thigh
-
medial thigh
Question 55
Question
What does the common fibular deep branch innervate muscle wise?
Answer
-
anterior leg
-
posterior leg
-
lateral leg
-
medial leg
Question 56
Question
What does the superficial branch of the common fibular innervate muscle-wise?
Answer
-
anterior leg
-
posterior leg
-
lateral leg
-
medial leg
Question 57
Question
What does the tibial nerve innervate muscle-wise?
Answer
-
posterior leg
-
anterior leg
-
medial leg
-
lateral leg
-
sole of the foot
-
top of the foot
Question 58
Question
The femoral nerve's sensory innervation includes the [blank_start]anterior[blank_end] thigh and [blank_start]medial[blank_end] leg.
Question 59
Question
The obturator nerve's sensory innervation is the [blank_start]medial[blank_end] thigh.
Question 60
Question
The [blank_start]deep[blank_end] branch of the common fibular's sensory innervation is the skin of the upper lateral leg.
Question 61
Question
The deep branch of the common fibular's sensory innervation is the [blank_start]lower[blank_end] [blank_start]lateral[blank_end] leg and [blank_start]dorsal[blank_end] foot.
Question 62
Question
Both the [blank_start]sciatic[blank_end] nerve (which bifurcates in the [blank_start]popliteal[blank_end] fossa into the [blank_start]tibial[blank_end] nerve and the common fibular nerve) and the [blank_start]tibial[blank_end] nerve innervate (sensory-wise) the [blank_start]posterior[blank_end] thigh and [blank_start]posterior[blank_end] leg and [blank_start]plantar[blank_end] foot.
Answer
-
sciatic
-
popliteal
-
tibial
-
tibial
-
posterior
-
posterior
-
plantar
Question 63
Question
The sciatic nerve's spinal roots are [blank_start]L4-S3[blank_end].
Answer
-
L4-S3
-
L2-S3
-
L1-L2
-
L3-S2
-
L4-S2
Question 64
Question
Dorsiflexion is a sign of damage to what nerve?
Question 65
Question
Inability to dorsiflex (so basically having a foot drop) is indicative of damage to what nerve?
Question 66
Question
What movements does the femoral nerve allow?
Answer
-
flexion of hips
-
extension of the knee
-
extension of the hips
-
flexion of the knees
-
abduction of the leg
-
adduction of the leg
Question 67
Question
What innervates hip extension and knee flexion?
Answer
-
Inferior gluteal
-
sciatic nerve
-
superior gluteal
-
tibial
-
common fibular
Question 68
Question
The [blank_start]obturator[blank_end] nerve allows hip adduction. On the other hand, the [blank_start]superior[blank_end] [blank_start]gluteal[blank_end] nerve allows hip abduction.
Answer
-
obturator
-
superior
-
gluteal
Question 69
Question
What are the main types of arthritis?
Question 70
Question
[blank_start]Primary[blank_end] osteoarthritis and [blank_start]secondary[blank_end] osteoarthritis are the two types of osteoarthritis.
Question 71
Question
The three types of inflammatory arthritis: rheumatoid, [blank_start]crystal-induced,[blank_end] and [blank_start]psoriatic[blank_end].
Answer
-
crystal-induced,
-
psoriatic
Question 72
Question
What are the two types of crystal-induced arthritis?
Answer
-
gout
-
pseudogout
-
rheumatoid
-
psoriatic
-
none of the above
Question 73
Question
What is a degenerative disease that affects the joints, often due to wear and tear of articular cartilage?
Answer
-
osteoarthritis
-
synovitis
-
crepitus
-
joint stiffness
-
subarticular sclerosis
Question 74
Question
How might osteoarthritis present?
Answer
-
joint stiffness in the evening/morning
-
generally worse after walking
-
palpable bony swelling on the hands' interphalangeal joints
-
reduced range of motion
-
crepitus in the joints
-
insomnia
-
generalized swelling around major joints
-
locked joints
-
synovitis
Question 75
Question
An X-ray investigation of osteoarthritis will show...
Answer
-
reduced joint space
-
subarticular sclerosis
-
osteophytes
-
bony cysts
-
glued up joint space
-
cartilage cysts
-
osteocytes
Question 76
Question
For osteoarthritis, the only management is supportive/palliative.
Question 77
Question
What is an autoimmune disease that also ends in joint destruction?
Answer
-
rheumatoid arthritis
-
septic arthritis
-
osteoarthritis
-
gout
Question 78
Question
What is characteristic of rheumatoid arthritis?
Answer
-
specific joint pain in the morning
-
specific joint pain in the evening
-
joints affected symetrically
-
joint inflammation
-
joints affected asymetrically
Question 79
Question
All of these are part of the management of rheumatoid arthritis BUT
Question 80
Question
Which of the following regarding the investigation of rheumatoid arthritis is true?
Answer
-
will find rheumatoid factor in serum
-
x-ray will reveal bone erosion
-
x-ray will reveal reduced joint space
-
periarticular osteopenia
-
visible deformity
-
x-ray will reveal
-
excessive bone growth
Question 81
Question
The deposition of monosodium urate crystals in joints is a type of arthritis called [blank_start]gout[blank_end]. This usually happens if there are high levels of [blank_start]uric[blank_end] acid in the blood. The risk factors are [blank_start]obesity[blank_end] and [blank_start]purine[blank_end] (one of the building blocks of DNA) rich food. The most common occurence is at the big [blank_start]toe[blank_end] joint. Symptoms include [blank_start]synovitis[blank_end] (swelling of the joint), [blank_start]malaise[blank_end] (general ill-feeling), and [blank_start]tophi[blank_end] [blank_start]lumps[blank_end] (crystals.) These crystals are visible under polarized light microscopy. The primary way to test for this is to take [blank_start]aspirate[blank_end] fluid in the joint, gram stain it to rule out septic arthritis, and test the fluid for levels of uric acid.
Answer
-
gout
-
uric
-
purine
-
obesity
-
toe
-
synovitis
-
malaise
-
tophi
-
lumps
-
aspirate
Question 82
Question
The treatment plan is for what?
1. NSAIDs
2. Colchicine
3. Corticosteroids
Answer
-
chronic gout
-
acute gout
-
goutisis
-
pseudogout
Question 83
Question
Other than lifestyle changes to reduce urate levels, we give those with [blank_start]chronic[blank_end] [blank_start]gout[blank_end] the drug allopurinol.
Question 84
Question
Accumulation of monosodium urate monohydrate crystals in joints causes pseudogut as well.
Question 85
Question
What is of clinical importance regarding septic arthritis?
Answer
-
medical emergency
-
take the aspirate fluid in join and gram stain it
-
take a blood culture (full blood count) and see if there's a high amount of leukocytes
-
take a blood culture (full blood count) and see if there's a high amount of c-reactive protein
-
x-ray will show increased joint space
-
x-ray will show decreased joint space
-
chronic/gradual development
-
to manage, should drain aspirate fluid
-
to manage, should give antibiotics
-
presents like an infection plus reduced joint functionality and synovitis
Question 86
Question
Prostacyclin is prostaglandin [blank_start]12[blank_end], which is produced by the [blank_start]epithelium[blank_end]. Prostacyclin prevents excess [blank_start]platelet[blank_end] [blank_start]aggregation[blank_end] during the platelet plug.
Answer
-
12
-
epithelium
-
platelet
-
aggregation
Question 87
Question
[blank_start]Thrombocytoplenia[blank_end] is when there are too few platelets in the body. It can be treated with [blank_start]thrombopoietin[blank_end], which will increase the platelet number. It takes [blank_start]6[blank_end] days for progress to be apparent though.
Answer
-
Thrombocytoplenia
-
thrombopoietin
-
6
Question 88
Question
Platelets only adhere to smooth epithelial surfaces.
Question 89
Question
[blank_start]Von[blank_end] [blank_start]Willebrand[blank_end] Disease is when a person is missing vWF and therefore have difficulty with [blank_start]hemostasis[blank_end] (the stopping of bloodloss.)
Answer
-
Willebrand
-
Von
-
hemostasis
Question 90
Question
If there is a suspicion of liver disease, one should check if [blank_start]coagulation[blank_end] is affected because it very well could be.
Question 91
Question
Coagulation can be affected in:
diseases affecting [blank_start]protein[blank_end] [blank_start]formation[blank_end]
[blank_start]genetic[blank_end] diseases of the clotting [blank_start]factors[blank_end]
Answer
-
protein
-
formation
-
genetic
-
factors
Question 92
Question
There are 2 coagulation pathways: they meet up at factor [blank_start]10[blank_end].
The intrinsic pathway begins with factor [blank_start]12[blank_end]. This is when the [blank_start]inside[blank_end] of the blood vessel gets damage without any necessary external damage. Ex: [blank_start]hypertension[blank_end] (erodes.)
The extrinsic pathways begin with factor [blank_start]3[blank_end]. Damage from [blank_start]outside[blank_end] to the blood vessel. Usually accompanies tissue damage.
Answer
-
10
-
12
-
3
-
hypertension
-
inside
-
outside
Question 93
Question
The outside aspect of a scab is called an [blank_start]eschar[blank_end].
Question 94
Question
What is true regarding vitamin K?
Answer
-
produces anticoagulant protein c
-
produces coagulant protein z
-
produces anticoagulant protein s
-
produces factor 7
-
produces factor 9
-
produces prothrombin
-
produces factor 10
-
produces fibrinogen
-
produces factor 5
Question 95
Question
Vitamin K helps with bone metabolism by increasing calcification.
Question 96
Question
Vitamin K is from kale and kiwi.
Question 97
Question
Vitamin K is stored in muscle
Question 98
Question
The "tea and toast" diet is associated with vitamin [blank_start]B[blank_end][blank_start]12[blank_end] deficiency. Patients can present as [blank_start]weakness[blank_end], paresthesia (tingliness), and [blank_start]irritability[blank_end]. Vegetarians and [blank_start]vegans[blank_end] often have this. B12 helps make the [blank_start]myelin[blank_end] [blank_start]sheath[blank_end] in neurons.
Answer
-
B
-
12
-
weakness
-
irritability
-
myelin
-
sheath
-
vegans
Question 99
Question
[blank_start]Allodynia[blank_end] is when the patient complains that "everything" is painful, even stimuli that are not usually painful.
Question 100
Question
[blank_start]Hyperalgesia[blank_end] is when you have an increased pain response to painful stimulus.
Question 101
Question
Primary healing is when you actively bring together both edges of the wound to stimulate heealing.
Question 102
Question
Secondary healing is when you leave the wound alone to heal
Question 103
Question
Warfarin is given following
Answer
-
a prothrombin time test
-
a K reductase time test
-
a Synacthen test
-
a plasmin time test
-
a water deprifation test
Question 104
Question
Warfarin is an anticoagulant.
Question 105
Question
Warfarin works essentially by blocking the enzyme [blank_start]vitamin[blank_end] [blank_start]K[blank_end] [blank_start]reductase[blank_end], and thus blocks all the stuff said vitamin makes. It is prescribed for heart conditions--such as [blank_start]atrial[blank_end] [blank_start]fibrillation[blank_end]--and for thrombotic conditions--[blank_start]deep[blank_end] [blank_start]vein[blank_end] thrombosis and [blank_start]pulmonary[blank_end] embolisms are the classics. Also, it is given post [blank_start]orthopedic[blank_end] surgery.
Answer
-
vitamin
-
K
-
reductase
-
atrial
-
fibrillation
-
deep
-
vein
-
pulmonary
-
orthopedic
Question 106
Question
Vitamin K enhances the functionality of Warfarin.
Question 107
Question
Antithrombin III deficiency is a hereditary, relatively harmless, and common condition.
Question 108
Question
DVT and pulmonary embolisms are both complications of Antithrombin III deficiency.
Question 109
Question
Warfarin acts on the thrombus by dissolving it.
Question 110
Question
TPA ([blank_start]tissue[blank_end] [blank_start]plasminogen[blank_end] [blank_start]activator[blank_end]) is used in drugs dealing with thrombotic problems. It [blank_start]dissolves[blank_end] the clot.
Answer
-
tissue
-
plasminogen
-
activator
-
dissolves
Question 111
Question
What causes Hemophilia A?
Answer
-
Factor 8 deficiency
-
Factor 9 deficiency
-
Factor 12 deficiency
-
Factor 5 deficiency
Question 112
Question
What is Hemophilia B due to?
Answer
-
Factor 7 deficiency
-
Factor 5 deficiency
-
Factor 9 deficiency
-
Factor 11 deficiency
Question 113
Question
[blank_start]Vasculogenesis[blank_end] is the formation of new blood vessels completely from scratch from [blank_start]endothelial[blank_end] precursor cells.
Answer
-
Vasculogenesis
-
endothelial
Question 114
Question
Myofibroblasts need a lot of extracellular matrix.
Question 115
Question
Mature tissue contains [blank_start]dense[blank_end] collagen (collagen [blank_start]I[blank_end]) and blood channels. It is [blank_start]acellular[blank_end] connective tissue.
Question 116
Question
What is true regarding Hypertrophic scars?
Question 117
Question
What is true regarding contracture scars?
Question 118
Question
What is true regarding keloid scars?
Question 119
Question
Sunken scars have a [blank_start]pitted[blank_end] kind of appearance. An example: [blank_start]chickenpox[blank_end] scars.
Question 120
Question
Scar treatment is often unecessary.
Question 121
Question
Which of these are ways to treat scars?
Answer
-
topical silicone gel
-
pressure dressings
-
steroids
-
make- up
-
cosmetic surgery
-
plastic surgery
-
flucloxacillin
-
acupuncture