Question 1
Question
Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.
Question 2
Question
Direct-acting skeletal muscle relaxants interfere with __________ ions involved in skeletal muscle contraction.
Answer
-
calcium
-
phosphorus
-
sodium
-
magnesium
Question 3
Question
Neuromuscular blocking drugs work by:
Answer
-
a. disrupting nerve impulses at motor end plates
-
b. disrupting nerve impulses at post-synaptic neurons
-
c. both the above are true
Question 4
Question
Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.
Question 5
Question
The __________ is that area where a terminal nerve ending innervates a muscle.
Question 6
Question
Curare alkaloids:
Answer
-
Paralyze the diaphragm preventing breathing
-
Cross the blood-brain-barrier
-
Make one go unconscious immediately
-
Compete with phosphorus involved in muscle contraction
Question 7
Question
The antidote for curare alkaloids are __________ drugs.
Answer
-
anti-cholinesterase
-
cholinesterase
Question 8
Question
Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.
Question 9
Question
Succinylcholine is metabolized slower than acetylcholine, resulting in:
Question 10
Question
Parkinson’s disease:
Answer
-
a. has a deficiency of dopamine
-
b. has an excess of acetylcholine
-
c. is a movement disorder
-
d. all the above are true
Question 11
Question
Akinesia is the absence of:
Question 12
Question
The 2 types of therapy for Parkinson’s disease are __________ and __________ drugs.
Answer
-
anti-cholinergic; dopaminergic
-
anti-cholinergic; anti-cholinesterase
-
cholinergic; dopaminergic
-
cholinergic; anti-cholinesterase
Question 13
Question
Another name for anti-cholinergic drugs is __________ drugs.
Answer
-
parasympatholytic
-
sympatholytic
Question 14
Question
Too much acetylcholine will excite the CNS causing parkinsonian tremor.
Question 15
Question
Dopaminergic drugs act on the brain to improve motor function.
Question 16
Question
Levodopa can convert to dopamine:
Question 17
Question
COMT inhibitors are reversible.
Question 18
Question
Triptans are used to treat:
Answer
-
musculoskeletal issues
-
migraines
-
seizures
-
Parkinson’s disease
Question 19
Question
5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:
Answer
-
migraines
-
musculoskeletal issues
-
seizures
-
Parkinson’s disease
Question 20
Question
Abortive anti-migraine drugs are designed to stop a migraine: