15526529
Description
Quiz by Med Student , updated more than 1 year ago
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Created by Med Student
about 6 years ago
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Question 1
Question
Fluoroquinoiones are:
Answer
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Gentamycin
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Moxifloxacin
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Ciprofloxacin
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Levofloxacin
Question 2
Question
Mechanism of action of quinolones is:
Answer
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inhibition of protein synthesis
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inhibition of cell wall synthesis
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inhibition of topoisomerase II and IV
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inhibition of DNA transcription and replication
Question 3
Question
Fluoroquinolones have:
Answer
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broad antibacterial spectrum
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narrow antibacterial spectrum
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bacteriostatic effect
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bactericidal effect
Question 4
Question
Point out the correct statements for pharmacokinetics of fluoroquinolones:
Answer
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bad oral absorption and are administered always parenterally
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distribute well into all tissues and body fluids
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inhibit some liver cytochromes
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most of them are excreted renally
Question 5
Question
Fluoroquinolones are used for treatment of:
Answer
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Urinary tract infections
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Respiratory infections
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Skin infections
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Gl infections
Question 6
Question
Adverse drug reactions of fluoroquinolones are:
Answer
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articular cartilage erosion (arthropathy)
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hypertension
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seizures in patients with epilepsy
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prolongation of QT interval
Question 7
Question
Quinolones are contraindicated in
Answer
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pregnancy and breast-feeding
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children under 18 years of age
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patients with epilepsy
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patients with renal failure
Question 8
Question
Drug interactions of fluoroquinolones are:
Answer
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increase serum levels of theophyiline by inhibiting its metabolism
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decrease serum levels of theophyiline by inducing its metabolism
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synergism with beta-lactams
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calcium and other divalent cations decrease their absorption
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