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Cholinergic Drugs- Pharmacology 4th Year- PMU

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Cholinergic Drugs- Pharmacology 4th Year- PMU
Med Student
Quiz by Med Student , updated more than 1 year ago
Med Student
Created by Med Student about 6 years ago
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Resource summary

Question 1

Question
Point out the cholinergic neurons
Answer
  • preganglionic sympathetic
  • postganglionic sympathetic
  • preganglionic parasympathetic
  • postganglionic parasympathetic

Question 2

Question
Muscarinic cholinergic receptors are located in:
Answer
  • skeletal muscles
  • bronchial smooth muscles
  • heart
  • smooth muscles of GIT

Question 3

Question
Nicotinic cholinergic receptors are located in:
Answer
  • autonomic ganglia
  • adrenal gland medulla
  • heart muscle
  • skeletal muscles

Question 4

Question
Pharmacological effects of Acetylcholine are:
Answer
  • bradycardia
  • tachycardia
  • increased digestive (abundant saliva), bronchial, cutaneous, (sweat) and lacrimal secretions
  • increased tone and peristaltic contractions of GIT

Question 5

Question
M-receptor agonist used for treatment of glaucoma is:
Answer
  • Atropini sulfas
  • Pilocarpini hydrochloridum
  • Neostigmini methylsulfas
  • Galantamini bromidum

Question 6

Question
What are the effects of Pilocarpine after eye application?
Answer
  • mydriasis
  • miosis
  • increases the intraocular pressure
  • decreases the intraocular pressure

Question 7

Question
Clinical indications for prescribing N-receptor agonists are:
Answer
  • smoking cessation
  • atherosclerosis
  • premedication in anesthesia
  • muscle relaxation

Question 8

Question
Acetylcholine esterase inhibitors (anticholinesterases) are:
Answer
  • lpratropii bromidum
  • Galantamine bromidum
  • Neostigmine methylsulfas
  • Pyridostigmine bromidum

Question 9

Question
Indications for the clinical use of anticholinesterases are:
Answer
  • paralytic ileus
  • atropine intoxication
  • spastic bronchitis
  • as antidote of tubocurarine

Question 10

Question
Anticholinesterases are contraindicated in:
Answer
  • bronchial asthma
  • paralytic ileus
  • epilepsy
  • bradycardia

Question 11

Question
Point out the major features of the irreversible acetylcholine-esterase inhibitors:
Answer
  • They are organophosphate agents
  • Cause long-lasting elevation of acetylcholine levels
  • Their effect is antagonized by cholinolytic agents
  • Obidoxime is their specific antagonist

Question 12

Question
Symptoms of organophosphate intoxication can be treated with:
Answer
  • Acetylcholine
  • Atropine sulphas
  • Reactivators of acetylcholine esterase enzyme
  • Inhibitors of acetylcholine esterase

Question 13

Question
Antimuscarinic receptor antagonists are:
Answer
  • Atropini sulfas
  • Butylscopolamine
  • Atracurium besilas
  • Ipratropium bromidum

Question 14

Question
Synthetic antimuscarinic drugs are:
Answer
  • Pilocarpini hydrochloridum
  • Ipratropium bromidum
  • Butylscopolamine
  • Tiotropium bromidum

Question 15

Question
Pharmacological effects of antimuscarinic drugs are:
Answer
  • tachycardia
  • intestinal smooth muscle relaxation
  • mydriasis
  • decrease the secretion of exocrine glands

Question 16

Question
Clinical indications for prescribing antimuscarinic drugs are:
Answer
  • bronchial asthma
  • spasm of the smooth muscles of GlT
  • to elicit papillary dilation
  • glaucoma

Question 17

Question
Adverse drug reactions of Atropine are:
Answer
  • dry mouth
  • tachycardia
  • difficulties in seeing close objects
  • disorientation and hallucinations

Question 18

Question
Symptoms of intoxication with antimuscarinic agents are treated with:
Answer
  • Obidoxime
  • Anticholinesterases
  • Atropine sulphas
  • Acetylcholine

Question 19

Question
Non-depolarizing neuromuscular blockers paralyse the skeletal muscles in the following order:
Answer
  • head and neck, limbs, trunk, diaphragm and intercostal muscles
  • limbs, trunk, diaphragm and intercostal muscles, head and neck
  • diaphragm and intercostal muscles, head and neck, limbs
  • trunk, diaphragm and intercostal muscles, head and neck, limbs

Question 20

Question
Which of the following drugs are non-depolarising muscle blockers?
Answer
  • Atracurium besilas
  • Pancuronium bromidum
  • Suxamethonium chloridum
  • Tubocurarine hydrochloridum

Question 21

Question
Adverse drug reactions of non-depolarizing muscle relaxants are:
Answer
  • histamine release
  • hypotension
  • hypertension
  • allergic reaction

Question 22

Question
Drug interactions can occur in concomitant use Of peripheral-acting muscle relaxants and:
Answer
  • aminoglycoside antibiotics
  • calcium antagonists
  • halogen anaesthetics
  • cardiac glycosides

Question 23

Question
Which of the following drugs will antagonise the effect of the non-depolarizing neuromuscular blockers?
Answer
  • Anticholinesterases
  • MAO inhibitors
  • Antimuscarinic agents
  • Aminoglycoside antibiotics

Question 24

Question
What are the main features of Suxamethonium chioridum:
Answer
  • short-lasting effect
  • has no antagonist
  • anticholinesterases prolong its effect
  • oral administration

Question 25

Question
Adverse drug reactions of depolarizing muscle relaxants are-
Answer
  • tremor
  • arrhythmia
  • allergic reactions
  • prolonged neuromuscular blockade in people with plasma cholinesterase deficiency

Question 26

Question
Indications for treatment with central muscle relaxants are-
Answer
  • spasms of the skeletal muscles as a result of CNS damage
  • multiple sclerosis
  • surgery interventions
  • myasthenia gravis

Question 27

Question
Which of drugs are central acting muscle relaxants?
Answer
  • Tetrazepam
  • Tolperison
  • Bromocriptine
  • Baclofen
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