L33 Therapeutics of T2DM

Description

PHCY310 Quiz on L33 Therapeutics of T2DM, created by Mer Scott on 16/04/2019.
Mer Scott
Quiz by Mer Scott, updated more than 1 year ago
Mer Scott
Created by Mer Scott over 5 years ago
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Resource summary

Question 1

Question
- Pre-diabetes: HbA1c [blank_start]41-49[blank_end] mmol/mol Patients should be advised on diet and lifestyle modification​. If >[blank_start]35[blank_end] do CVR assessment. Measure HbA1c [blank_start]yearly[blank_end]. - Diabetes:​ HbA1c ≥ [blank_start]50[blank_end] mmol/mol Full diabetes management​
Answer
  • 41-49
  • 50
  • 35
  • yearly

Question 2

Question
An HbA1c measurement of > 86 mmol/mol indicates severe diabetes.
Answer
  • True
  • False

Question 3

Question
Treatment steps: 1. [blank_start]Metformin[blank_end] is first line​ ([blank_start]Acarbose[blank_end]* if patient can’t take metformin or sulphonylureas) 2. Add a [blank_start]sulphonylurea or a DPP-4 inhibitor​[blank_end] 3. [blank_start]Pioglitazone[blank_end] in addition to, or instead of, metformin ± sulphonylurea​ 4. Add [blank_start]insulin[blank_end], usually once or twice daily. and, IF hypertensive (likely); 5. An ACE inhibitor,​ or an [blank_start]angiotensin II receptor blocker[blank_end] (ARB) if not tolerated​ *Low effect, GI tarcet ADRs
Answer
  • Metformin
  • Acarbose
  • sulphonylurea or a DPP-4 inhibitor​
  • Pioglitazone (PPAR-gamma activator)
  • insulin
  • angiotensin II receptor blocker
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