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Pharmacy/Pharmacokinetics (15% of exam)

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Veterinary Nursing Year 2 Quiz on Pharmacy/Pharmacokinetics (15% of exam), created by Jessica Whittick on 29/08/2019.
Jessica Whittick
Quiz by Jessica Whittick, updated more than 1 year ago
Jessica Whittick
Created by Jessica Whittick about 5 years ago
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Resource summary

Question 1

Question
Which Act controls the use of Veterinary Medicines
Answer
  • Veterinary Medicines Regulations
  • Veterinary Medicines Guidelines
  • Veterinary Pharmacy Regulations
  • Misuse of Drugs Act 1971

Question 2

Question
Which governing body oversee the legislation for Veterinary Medicines on behalf of DEFRA?
Answer
  • Veterinary Medicines Regulations
  • Veterinary Medicines Directorate
  • Misuse of Drugs Act 1971

Question 3

Question
Which Act controls the use of controlled drugs?
Answer
  • Misuse of Drugs Act 1971
  • Misuse of Veterinary Medicines Act 1971
  • Veterinary Medicines Regulations

Question 4

Question
Tablets which aren't digested before they have an effect are:
Answer
  • sugar coated
  • enteric coated
  • gelatin coated

Question 5

Question
Choose the one disadvantage of the parenteral route of administration among the advantages
Answer
  • rapid absorption of the drug
  • suitable for unconscious patients
  • low concentration of drug required
  • no risk of degradation of the drug by digestive juices
  • owners cannot regularly use it as a route

Question 6

Question
Intramuscular injections are given at
Answer
  • 90degreesC
  • 45degreesC
  • 180degreesC
  • 25degreesC

Question 7

Question
At what angle are subcutaneous injections given
Answer
  • 90degreesC
  • 25degreesC
  • 45degreesC
  • 50degreesC

Question 8

Question
Two injections sites commonly used in the bird
Answer
  • brachial vein
  • cephalic vein
  • saphenous vein
  • jugular vein

Question 9

Question
Which route can you NOT use in birds
Answer
  • intra-coelum
  • intra-pleural
  • intra-articular
  • intra-cardia

Question 10

Question
Max amount in mls you can administer i/m in a dog
Answer
  • 5 mls
  • 2mls
  • 1 ml
  • 6mls

Question 11

Question
max amount in mls you can administer i/m to a cat
Answer
  • 2mls
  • 3mls
  • 5mls
  • 1ml

Question 12

Question
[blank_start]Pharmacodynamics[blank_end]: the way in which the functions of the body are affected by the drugs [blank_start]Pharmacokinetics[blank_end]: the way in which drugs are absorbed, metabolised and excreted by the body
Answer
  • Pharmacodynamics
  • Pharmacokinetics

Question 13

Question
Drugs are primarily metabolised in the [blank_start]liver[blank_end]. Drugs are primarily excreted through the [blank_start]kidney[blank_end]. Oral drugs are primarily absorbed through the [blank_start]digestive tract[blank_end].
Answer
  • liver
  • kidney
  • digestive tract

Question 14

Question
Bioavailability is...
Answer
  • the amount of drug that reaches the digestive tract intact
  • the amount of drug that reaches the blood-brain barrier intact
  • the amount of drug that is biologically available following metabolism by the liver
  • the amount of drug that reaches the circulation intact

Question 15

Question
The therapeutic index of a drug is:
Answer
  • how much therapeutic effect it can have at the lowest dose
  • how much reaches the circulation intact to have a therapeutic effect
  • the ratio between the dosage of the drug that causes the desired effect and that which causes toxic effects
  • the ratio between the dosage of the drug that induces a systemic reaction and that which causes an allergic reaction

Question 16

Question
Which drug has the widest therapeutic index
Answer
  • drontal
  • propofol
  • insulin
  • diazepam

Question 17

Question
Which ectoparasiticide must NOT be administered to cats
Answer
  • Permethrin
  • Praziquantel
  • Ivermectin

Question 18

Question
Which medication must NOT be used to treat ringworm in pregnant animals
Answer
  • Griseofulvin
  • Imidocarb
  • Permethrin
  • Fenbendazole

Question 19

Question
What is the meat withdrawal period following administration of drugs into the food chain
Answer
  • 30 days
  • 25 days
  • 28 days
  • 10 days

Question 20

Question
Metacam is the...
Answer
  • trade (proprietary) name
  • generic (chemical) name

Question 21

Question
Who is responsible for inspecting Veterinary Practice Premises in relation to the use of pharmaceuticals?
Answer
  • DEFRA
  • RCVS
  • VMD
  • BVA

Question 22

Question
The ambient temperature of a pharmacy should not exceed
Answer
  • 12 degrC
  • 18 degrC
  • 25 degrC
  • 30 degrC

Question 23

Question
Which piece of legislation sets out the legal categories of veterinary drugs in the UK?
Answer
  • The RCVS Storage and Dispensing of Medicines 2008
  • The Veterinary Medicines Regulations 2005
  • The Misuse of Drugs Act 1971
  • The Veterinary Medicines Directorate

Question 24

Question
Which of the following is a Schedule 2 drug
Answer
  • Fentanyl
  • Pentobarbitone
  • Diazepam
  • Anabolic Steroids

Question 25

Question
For how long is a prescription for a controlled drug valid?
Answer
  • 14 days
  • 28 days
  • 1 month
  • 6 months

Question 26

Question
For how long is prescription for a general prescription drug valid?
Answer
  • 14 days
  • 28 days
  • 1 month
  • 6 months

Question 27

Question
In the UK, the Veterinary Medicines Regulations 2005
Answer
  • Governs the manufacture, storage, handling and dispensing of veterinary medicines
  • Governs the manufacture and storage of veterinary medicines
  • Governs the handling and dispensing of veterinary medicines
  • Regulates the legislation of controlled drugs only

Question 28

Question
Regarding categories of drugs, which ones must be supplied from registered premises?
Answer
  • POM-V and POM-VPS
  • POM and POM-V only
  • POM-V, POM-VPS, and NFA-VPS
  • POM-V, POM-VPS, NFA-VPS and AVM-GSL

Question 29

Question
A suspected adverse reaction to a veterinary medicine must be reported to:
Answer
  • VMD
  • RCVS
  • DEFRA
  • NOAH

Question 30

Question
A POM-V medicine:
Answer
  • may only be prescribed and dispensed by a VS
  • may only be prescribed by a VS or a pharmacist
  • may only be prescribed by a VS, but may be dispensed by either a VS or a pharmacist
  • may only be stored within a veterinary practice pharmacy

Question 31

Question
Which of the following is true regarding an AVM-GSL medicine?
Answer
  • it requires a written prescription from a RQP
  • it has a wide safety margin
  • special advice to clients is required to ensure its safe and effective use
  • the manufacturer does not have to prove safety, quality and efficacy to the same standards as other drugs

Question 32

Question
Regarding the dispensing of medicines, the abbreviation q8h means:
Answer
  • 3 times a day
  • every 8 hours
  • by injection every 8 hours
  • three times in 24 hours

Question 33

Question
A dog weighs 10kg and needs ampicillin twice a day for 5 days, the dose rate is 20mg/kg/day. the tablets available are 100mg. how many tablets should be dispensed?
Answer
  • 5
  • 10
  • 15
  • 20

Question 34

Question
A cat weighing 4kg needs an anaesthetic to repair a small laceration, the anaesthetic to be administered is ketamine hydrochloride. the dose rate is 1.5mg/kg i/m and the vial labelled is 100mg/ml. how many mg should be administered to the cat? how many mls would you administer?
Answer
  • 0.04mls
  • 0.06mls
  • 0.4mls
  • 0.6mls

Question 35

Question
Schedule [blank_start]3[blank_end]: e.g. methadone - locked cabinet, bound book, records kept for 2 yrs, signed for when ordered Schedule [blank_start]2[blank_end]: e.g. buprenorphine - signed for when ordered but don't need to record use
Answer
  • 2
  • 3
  • 4
  • 1

Question 36

Question
A fluted bottle indicates:
Answer
  • external use only
  • internal use only

Question 37

Question
What special precautions are given to clients when dispensing prednisolone?
Answer
  • wear gloves
  • wear a mask
  • CONTAINS PENICILLIN
  • do not handle if you are immuno-suppressed

Question 38

Question
What route of administration has a bioavailability of 1?
Answer
  • intravenous
  • intramuscular
  • sub cutaneous
  • intra-peritoneal

Question 39

Question
What is the term used to describe the time for 50% of the drug to be metabolised and excreted?
Answer
  • half life
  • half bioavailability
  • half effect
  • half metabolism

Question 40

Question
tick the legal requirements for a drug label
Answer
  • name and address of vet
  • warning signs
  • date dispensed
  • client name and address
  • strength and type of drug

Question 41

Question
Tick everything that applies to tablets
Answer
  • dry presentation of medicine
  • cheaper, can be scored and broken up
  • active drug in an inert substance that binds it together
  • can be coated to protect from moisture, stomach acid, to hide bitter taste

Question 42

Question
Heroin, cannabis, cocaine - schedule [blank_start]1[blank_end] buprenorphine, butorphanol, tramadol - schedule [blank_start]3[blank_end] diazepam, anabolic steroids - schedule [blank_start]4[blank_end] pethidine, morphine, methadone - schedule [blank_start]2[blank_end]
Answer
  • 1
  • 3
  • 4
  • 2

Question 43

Question
o.d., S.i.d, u.i,d - [blank_start]once daily[blank_end] o.m - [blank_start]every morning[blank_end] o.n - [blank_start]every night[blank_end] b.d - [blank_start]twice per day[blank_end] t.d.s - [blank_start]3x daily[blank_end] q.d.s - [blank_start]4x daily[blank_end] q.q.h - [blank_start]every 4 hours[blank_end] a.c - [blank_start]before food[blank_end] p.c - [blank_start]post food[blank_end] p.r.n - [blank_start]as required[blank_end] stat - [blank_start]STAT[blank_end] q.h - [blank_start]hourly[blank_end] q.8.h - [blank_start]every 8 hours[blank_end]
Answer
  • once daily
  • every morning
  • every night
  • twice per day
  • 3x daily
  • 4x daily
  • every 4 hours
  • before food
  • post food
  • as required
  • STAT
  • hourly
  • every 8 hours

Question 44

Question
The Therapeutic effects is [blank_start]desired[blank_end], the Side effects are [blank_start]expected[blank_end], the Adverse Effects are [blank_start]unexpected[blank_end]
Answer
  • desired
  • expected
  • unexpected

Question 45

Question
Order of the pharmacokinetic pathway: [blank_start]A - Absorption[blank_end][blank_start]D - Distribution[blank_end] [blank_start]M - Metabolism[blank_end][blank_start]E - Excretion[blank_end]
Answer
  • A - Absorption
  • D - Distribution
  • M - Metabolism
  • E - Excretion

Question 46

Question
[blank_start]Hydrophilic[blank_end] drugs are more readily absorbable via i/v route, stay in the blood and tissue fluids [blank_start]Lipophilic[blank_end] drugs are distributed through all body tissues and can be deposited in fats, cell membranes are mostly phospholipids, so this is useful
Answer
  • Hydrophilic
  • Lipophilic

Question 47

Question
Which is more likely to enter the brain by crossing the blood brain barrier? (and placental barrier)
Answer
  • hydrophilc drugs
  • lipophilic drugs
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