Question 1
Question
Where do endocrine cells secrete their hormones into?
Answer
-
Target cells
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Blood
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Out of ducts
-
Glands
Question 2
Question
What is a neuroendocrine cell?
Answer
-
A cell that released hormones into the blood upon depolarisation
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A cell that releases neurotransmitter into the blood upon depolarisation
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A cell that releases hormones across the synaptic cleft upon depolarisation
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A cell that releases hormones onto neighbouring cells upon depolarisation
Question 3
Question
What type of chemical signalling occurs when a cell targets itself?
Answer
-
Autocrine
-
Paracrine
-
Endocrine
-
Neuroendocrine
Question 4
Question
What type of chemical signalling occurs when a cell targets a neighbouring cell?
Answer
-
Paracrine
-
Autocrine
-
Endocrine
-
Neuroendocrine
Question 5
Question
What type of signalling occurs when a cell releases a signal into the blood to be carried to its distant target cell?
Answer
-
Paracrine
-
Autocrine
-
Endocrine
-
Neuroendocrine
Question 6
Question
Which of the following hormones are secreted by neurosecretory cells?
Question 7
Question
Which of the following hormones are secreted by epithelial tissues?
Question 8
Question
What gives a hormone a long half-life?
Question 9
Question
The following questions will be about protein/peptide hormones. What must happen to preprohormones to form active prohormones?
Question 10
Question
How are active protein/peptide hormones released?
Question 11
Question
Are protein/peptide hormones protein-bound in circulation?
Question 12
Question
Which is true of protein hormones in circulation?
Answer
-
Long half-life
-
Short half-life
Question 13
Question
The following questions will be about steroid hormones. What are steroid hormones derived from?
Answer
-
Cholesterol
-
Proteins
-
Amines
-
DNA
Question 14
Question
Steroid hormones are lipid soluble.
Question 15
Question
Steroid hormones are stored in glands.
Question 16
Question
Are steroid hormones protein-bound in circulation?
Question 17
Question
Which is true of steroid hormones?
Answer
-
Long half-lives
-
Short half-lives
Question 18
Question
The following questions will be about amine hormones. Most amine hormones are derived from...?
Answer
-
Tyrosine
-
Phenylalanine
-
Glutamate
-
Aspartate
Question 19
Question
Thyroid hormones are amine hormones.
Question 20
Question
Which subtype of amine hormone is lipid-soluble?
Question 21
Question
Which subtype of amine hormone is water-soluble?
Question 22
Question
Which subtype of amine hormone is protein-bound in circulation, thus giving it a long half-life?
Question 23
Question
Which subtype of amine hormone is not bound to protein in circulation, giving it a short half-life?
Question 24
Question
Which subtype of amine hormones are stored intracellulary in secretory granules?
Question 25
Question
What are eicosanoids?
Question 26
Question
What are eicosanoids derived from?
Answer
-
Arachidonic acid
-
Diacylglycerol
-
Inositol
-
PIP2
Question 27
Question
Which of the following is an example of an eicosanoid?
Answer
-
Prostaglandin
-
Catecholamine
-
Adrenaline
-
Parathyroid hormone
Question 28
Question
Which of the following hormones have intracellular receptors that alter gene transcription?
Question 29
Question
Which of the following hormones have membrane-bound receptors that initiate second-messenger pathways to change enzyme activity?
Answer
-
Steroid hormones
-
Thyroid hormones
-
Protein/peptide hormones
-
Glycoproteins
-
Catecholamines
Question 30
Question
Drag and drop the correct answers to describe the mechanism of steroid hormones.
1. The steroid hormone crosses the membrane as it is [blank_start]lipid[blank_end]-soluble.
2. The steroid hormone binds to its receptor in the cytosol or [blank_start]nucleus[blank_end].
3. The receptor undergoes a [blank_start]conformational shape change[blank_end] that allows it to bind to DNA.
4. The receptor forms a [blank_start]dimer[blank_end] with another receptor unit and binds to DNA.
5. Binding alters [blank_start]transcription[blank_end] of target genes.
Question 31
Question
Which of the following can control hormone secretion?
Answer
-
Change in plasma ion concentration
-
Change in plasma nutrient concentration
-
Neurotransmitter release from neurones contacting endocrine cells
-
Upstream hormone/paracrine agents acting on endocrine cells
-
Conscious effort
-
Repetitive limb movement
-
Lipolysis
Question 32
Question
Drag and drop the correct labels to describe the anatomy of the pituitary gland.
Question 33
Question
During the development of the pituitary gland, the outpouching of what will form the posterior pituitary/neurohypophysis?
Question 34
Question
During the development of the pituitary gland, the outpouching of what will form the anterior pituitary/adenohypophysis?
Question 35
Question
Drag and drop the correct labels to describe the development of the pituitary gland.
Question 36
Question
Which of the following are secreted by the posterior pituitary/neurohypophysis?
Question 37
Question
Drag and drop the correct answers to describe the secretion of hormones by the posterior pituitary gland/neurohypophysis.
1. Specific neural stimuli lead to the synthesis of hormones in [blank_start]cell bodies[blank_end] of [blank_start]hypothalamic[blank_end] nuclei.
2. The hormones are transported down the [blank_start]axons[blank_end] of [blank_start]neuroendocrine[blank_end] cells.
3. The hormones are stored in [blank_start]Herring bodies[blank_end] in the nerve terminals.
4. The hormones are released directly into the [blank_start]venous blood[blank_end] of the posterior pituitary.
Answer
-
cell bodies
-
hypothalamic
-
thalamic
-
cortical
-
axons
-
neuroendocrine
-
endocrine
-
paracrine
-
Herring bodies
-
pituicytes
-
venous blood
-
tissue fluid
-
surrounding CSF
Question 38
Question
What is the effect of ADH?
Answer
-
Increased water resorption in the kidney
-
Decreased water resorption in the kidney
-
Increase in uterine contractions
-
Stimulation of the adrenal glands
Question 39
Question
Oxytocin increases uterine contractions during birth as well as milk ejection during suckling.
Question 40
Question
Drag and drop the correct answers to describe the mechanism of secretion of hormones from the anterior pituitary/adenohypophysis.
1. Specific neural stimuli lead to [blank_start]synthesis[blank_end] and release of [blank_start]hypothalamic[blank_end] hormones.
2. Hypothalamic hormones are released by [blank_start]neuroendocrine[blank_end] cells into blood vessels at the [blank_start]median eminence[blank_end].
3. The hypothalamic hormones travel down [blank_start]portal blood vessels[blank_end].
4. The hypothalamic hormones control release of anterior pituitary hormones.
Question 41
Question
Which part of the pituitary gland receives direct supply from the hypophyseal arteries?
Question 42
Question
Drag and drop the correct labels to describe the vasculature of the pituitary gland.
Answer
-
Supraoptic nuclei
-
Paraventricular nuclei
-
Superior hypophyseal artery
-
Infundibulum
-
Inferior hypophyseal artery
-
trabecular artery
-
Hypophyseal veins
-
Endocrine cells
-
Anterior pituitary/adenohypophysis
-
Posterior pituitary/neurohypophysis
Question 43
Question
Which of the following are secreted by the anterior pituitary/adenohypophysis?
Question 44
Question
What do the hypothalamic hypophysiotrophic hormones do?
Answer
-
Stimulate endocrine cells in the anterior pituitary/adenohypophysis to secrete hormones
-
Stimulate the release of hormones from the Herring bodies in the posterior pituitary/neurohypophysis
-
Increase body temperature
-
Initiate reproductive behaviour
Question 45
Question
Drag and drop the correct labels to describe the effect of hypothalamic hypophysiotrophic hormones on the anterior pituitary/adenohypophysis.
Answer
-
Thyrotropin-releasing hormone
-
Dopamine
-
Corticotropin-releasing hormone
-
Gonadotrophin-releasing hormone
-
Growth-hormone releasing hormone
-
Somatostatin
-
Thyrotroph cells
-
Lactotroph cells
-
Corticotroph cells
-
Gonadotroph cells
-
Somatotroph cells
-
Thyroid-stimulating hormone
-
Prolactin
-
Adrenocorticotrophic hormone
-
Luteinising hormone
-
Follicle-stimulating hormone
-
Growth hormone