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Question 1
Question
Which one of the following is NOT true about Kell system antibodies
Answer
-
Usually clinically significant IgG antibodies
-
Best detected in indirect antiglobulin tests
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Fail to react in enzyme tests
-
Do not activate complement
Question 2
Question
Antibodies to the Kell, Kidd and Duffy systems all share the following traits except
Answer
-
Can cause haemolytic disease of the newborn and foetus
-
Enhanced with enzyme treatment
-
Can cause haemolytic transfusion reactions
-
usually detected only by indirect antiglobulin test
Question 3
Question
Which of the following phenotypes is heterozygous
Answer
-
Fy(a-b+)
-
Jk(a+b+)
-
Lu(a-b-)HIV
-
Jk(a-b+)
Question 4
Question
Which of the antibodies from the following blood group systems shows a dosage effect?
Answer
-
Lutheran
-
Kell
-
Duffy
-
P
-
Lewis
Question 5
Question
Antibodies to k antigen are not commonly detected in transfusion screening because
Answer
-
k antigen is of high incidence
-
the antibodies do not cause transfusion reactions
-
antibodies best react at 4 degree (C)
-
The antigen is of low incidence
-
k antigen is not present on screening cells
Question 6
Question
Lewis system antibodies have not been implicated in haemolytic disease of the new born and foetus because
Answer
-
the antigens are not fully developed at birth
-
Lewis system antibodies do not cross the placenta
-
the antibodies are not clinically significant
-
the antigens are primarily plasma based
-
All of the above
Question 7
Question
The Donath-Landsteiner antibody is
Answer
-
an IgG auto anti-P
-
an IgM auto anti-P
-
an IgM auto anti-I
-
anti-IH that reacts at cold temperatures
Question 8
Question
Which of the following cells has the highest concentration of M antigens
Answer
-
MNSs
-
MNs
-
NSs
-
MSs
-
NS
Question 9
Question
Which of the following does not result in an Lu(a-b-) phenotype
Answer
-
Deletion of the genes on the Lu locus
-
Amorphic genes of the Lu locus
-
Delayed anamestic heamolytic transfusion reaction
-
A suppressor gene on the X-chromosome
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An inhibitor gene on another locus
Question 10
Question
The top and bottom pack comprises of
Answer
-
Single packs joined together
-
Triple pack
-
Double pack
-
Quadruple pack
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