2590652
Question 1
Question
Process used in an expression vector to increase yield of recombinant protein synthesis ?
Answer
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Translation initiation
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Promoter induction
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Transcription terminators
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Multiple cloning sites
Question 2
Question
Rothera’s test is utilised for detection of?
Answer
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Glucose
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Proteins
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Urea
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Ketone bodies
Question 3
Question
Decreased energy production in thiamine deficiency is due to?
Answer
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It is a cofactor for oxidative reduction
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It is required for transamination reactions
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It is a coenzyme for alpha ketoglutarate dehydrogenase and pyruvate dehydrogenase in citric acid cycle
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It is a coenzyme for transketolase in hexose monophosphate shunt
Question 4
Question
Which of the following enzymes is responsible for the transfer of amino groups from an amino acid to an alpha keto acid?
Answer
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Transaminase
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Transketolase
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Deaminase
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Lyase
Question 5
Question
Site of urea cycle is?
Answer
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Liver
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Kidney
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GIT
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Lungs
Question 6
Question
Which of the following is not a protein misfolding disorder?
Answer
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Tuberculosis
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Creutzfeldt Jakob disease
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Alzheimer’s disease
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Cystic fibrosis
Question 7
Question
Sphingomyelinase deficiency is characteristic of ?
Answer
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Fabry disease
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Krabbe’s disease
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Tay Sachs disease
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Niemann Pick disease
Question 8
Question
Xeroderma pigmentosum is produced as a result of a defect in :
Answer
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DNA polymerase III
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DNA exonuclease
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DNA ligase
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none
Question 9
Question
A genetic disorder renders fructose 1,6 — biphosphatase in liver less sensitive to regulation by fructose 2,6 — bi-phosphate. All of the following metabolic changes are observed in this disorder except:
Answer
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Level of fructose 1,6—biphosphate is higher than normal
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Level of fructose 1,6 — biphosphate is lower than normal
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Less pyruvate is formed
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Less ATP is generated
Question 10
Question
Alpha helix and Beta pleated sheet are examples of:
Answer
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Primary structure
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Secondary structure
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Tertiary structure
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Quaternary structure
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