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Biology I - Exam 4

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Quiz on Biology I - Exam 4, created by acbridges91 on 10/05/2015.
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Quiz by acbridges91, updated more than 1 year ago
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Question 1

Question
In trying to determine whether DNA or protein is the genetic material, Hershey and Chase made use of which of the following facts?
Answer
  • DNA contains sulfur, whereas protein does not.
  • DNA contains phosphorus, whereas protein does not.
  • DNA contains purines, whereas protein includes pyrimidines.
  • DNA contains nitrogen, whereas protein does not.

Question 2

Question
Which of the following investigators was (were) responsible for the following discovery? In DNA from any species, the amount of adenine equals the amount of thymine, and the amount of guanine equals the amount of cytosine.
Answer
  • Oswald Avery, Maclyn McCarty, and Colin MacLeod
  • Matthew Meselson and Franklin Stahl
  • Alfred Hershey and Martha Chase
  • Erwin Chargaff

Question 3

Question
It became apparent to Watson and Crick after completion of their model that the DNA molecule could carry a vast amount of hereditary information in which of the following?
Answer
  • side groups of nitrogenous bases
  • sequence of bases
  • phosphate-sugar backbones
  • complementary pairing of bases

Question 4

Question
In an analysis of the nucleotide composition of DNA, which of the following will be found?
Answer
  • A + C = G + T
  • A = G and C = T
  • A = C
  • G + C = T + A

Question 5

Question
In the polymerization of DNA, a phosphodiester bond is formed between a phosphate group of the nucleotide being added and _____ of the last nucleotide in the polymer.
Answer
  • the 3' OH
  • a nitrogen from the nitrogen-containing base
  • the 5' phosphate
  • C6

Question 6

Question
Replication in prokaryotes differs from replication in eukaryotes for which of the following reasons?
Answer
  • The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes.
  • Prokaryotic chromosomes have histones, whereas eukaryotic chromosomes do not.
  • Prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many.
  • Prokaryotes produce Okazaki fragments during DNA replication, but eukaryotes do not.

Question 7

Question
What is meant by the description "antiparallel" regarding the strands that make up DNA?
Answer
  • The twisting nature of DNA creates nonparallel strands.
  • The 5' to 3' direction of one strand runs counter to the 5' to 3' direction of the other strand.
  • One strand contains only purines and the other contains only pyrimidines.
  • Base pairings create unequal spacing between the two DNA strands.

Question 8

Question
In E. coli, there is a mutation in a gene called dnaB that alters the helicase that normally acts at the origin. Which of the following would you expect as a result of this mutation?
Answer
  • Replication will require a DNA template from another source.
  • No replication fork will be formed.
  • Replication will occur via RNA polymerase alone.
  • Additional proofreading will occur.

Question 9

Question
In E. coli, which enzyme catalyzes the elongation of a new DNA strand in the 5' → 3' direction?
Answer
  • helicase
  • primase
  • DNA ligase
  • DNA polymerase III

Question 10

Question
Eukaryotic telomeres replicate differently than the rest of the chromosome. This is a consequence of which of the following?
Answer
  • the evolution of telomerase enzyme
  • DNA polymerase that cannot replicate the leading strand template to its 5' end
  • gaps left at the 5' end of the lagging strand
  • gaps left at the 3' end of the lagging strand because of the need for a primer

Question 11

Question
How does the enzyme telomerase meet the challenge of replicating the ends of linear chromosomes?
Answer
  • It adds numerous GC pairs, which resist hydrolysis and maintain chromosome integrity.
  • It causes specific double-strand DNA breaks that result in blunt ends on both strands.
  • It adds a single 5' cap structure that resists degradation by nucleases.
  • It catalyzes the lengthening of telomeres, compensating for the shortening that could occur during replication without telomerase activity.

Question 12

Question
The DNA of telomeres has been highly conserved throughout the evolution of eukaryotes. This most likely reflects _____.
Answer
  • a critical function of telomeres
  • that new mutations in telomeres have been advantageous
  • the low frequency of mutations occurring in this DNA
  • continued evolution of telomeres

Question 13

Question
The difference between ATP and the nucleoside triphosphates used during DNA synthesis is that _____.
Answer
  • ATP contains three high-energy bonds; the nucleoside triphosphates have two
  • the nucleoside triphosphates have two phosphate groups; ATP has three phosphate groups
  • the nucleoside triphosphates have the sugar deoxyribose; ATP has the sugar ribose
  • ATP is found only in human cells; the nucleoside triphosphates are found in all animal and plant cells

Question 14

Question
A new DNA strand elongates only in the 5' to 3' direction because _____.
Answer
  • DNA polymerase begins adding nucleotides at the 5' end of the template
  • the polarity of the DNA molecule prevents addition of nucleotides at the 3' end
  • replication must progress toward the replication fork
  • DNA polymerase can add nucleotides only to the free 3' end

Question 15

Question
What is the function of topoisomerase?
Answer
  • unwinding of the double helix
  • relieving strain in the DNA ahead of the replication fork
  • stabilizing single-stranded DNA at the replication fork
  • elongating new DNA at a replication fork by adding nucleotides to the existing chain

Question 16

Question
What is the role of DNA ligase in the elongation of the lagging strand during DNA replication?
Answer
  • It unwinds the parental double helix.
  • It stabilizes the unwound parental DNA.
  • It joins Okazaki fragments together.
  • It synthesizes RNA nucleotides to make a primer.

Question 17

Question
Which of the following help(s) to hold the DNA strands apart while they are being replicated?
Answer
  • single-strand DNA binding proteins
  • DNA polymerase
  • ligase
  • primase

Question 18

Question
Which of the following would you expect of a eukaryote lacking telomerase?
Answer
  • a high probability of somatic cells becoming cancerous
  • a reduction in chromosome length in gametes
  • an inability to repair thymine dimers
  • an inability to produce Okazaki fragments

Question 19

Question
Within a double-stranded DNA molecule, adenine forms hydrogen bonds with thymine and cytosine forms hydrogen bonds with guanine. This arrangement _____.
Answer
  • determines the tertiary structure of a DNA molecule
  • permits complementary base pairing
  • allows variable width of the double helix
  • determines the type of protein produced

Question 20

Question
Semiconservative replication involves a template. What is the template?
Answer
  • one strand of the DNA molecule
  • an RNA molecule
  • single-stranded binding proteins
  • DNA polymerase

Question 21

Question
DNA is synthesized through a process known as _____.
Answer
  • conservative replication
  • semiconservative replication
  • transcription
  • translation

Question 22

Question
Who performed classic experiments that supported the semiconservative model of DNA replication?
Answer
  • Franklin and Wilkins
  • Watson and Crick
  • Hershey and Chase
  • Meselson and Stahl

Question 23

Question
DNA contains the template needed to copy itself, but it has no catalytic activity in cells. What catalyzes the formation of phosphodiester bonds between adjacent nucleotides in the DNA polymer being formed?
Answer
  • deoxyribonucleotide triphosphates
  • DNA polymerase
  • ribozymes
  • ATP

Question 24

Question
What is a major difference between eukaryotic DNA replication and prokaryotic DNA replication?
Answer
  • DNA replication in prokaryotic cells is conservative. DNA replication in eukaryotic cells is semi-conservative.
  • Prokaryotic replication does not require a primer.
  • DNA polymerases of prokaryotes can add nucleotides to both 3' and 5' ends of DNA strands, while those of eukaryotes function only in the 5' → 3' direction.
  • Prokaryotic chromosomes have a single origin of replication, while eukaryotic chromosomes have multiple origins of replication.

Question 25

Question
What is a telomere?
Answer
  • the ends of linear chromosomes
  • DNA replication during telophase
  • the site of origin of DNA replication
  • the mechanism that holds two sister chromatids together

Question 26

Question
A particular triplet of bases in the template strand of DNA is 5' AGT 3'. The corresponding codon for the mRNA transcribed is _____.
Answer
  • 5' TCA 3'
  • 3' ACU 5'
  • 3' UCA 5'
  • 3' UGA 5'

Question 27

Question
The genetic code is essentially the same for all organisms. From this, one can logically assume which of the following?
Answer
  • The same codons in different organisms translate into different amino acids.
  • Different organisms have different types of amino acids.
  • A gene from an organism can theoretically be expressed by any other organism.
  • DNA was the first genetic material.

Question 28

Question
Which of the following contradicts the one-gene, one-enzyme hypothesis?
Answer
  • Lactose intolerance is caused by a defective lactase gene.
  • A mutation in a single gene can result in a defective protein.
  • A single kinase gene can code for different related proteins, depending on the splicing that takes place post-transcriptionally.
  • Alkaptonuria results when individuals lack a single enzyme involved in the catalysis of homogentisic acid.

Question 29

Question
Which of the following specifies a single amino acid in a polypeptide chain?
Answer
  • the complementarity of DNA and RNA
  • the three-base sequence of mRNA
  • the base sequence of the tRNA
  • the aminoacyl-tRNA synthetase

Question 30

Question
In the process of transcription, _____.
Answer
  • mRNA attaches to ribosomes
  • proteins are synthesized
  • RNA is synthesized
  • DNA is replicated

Question 31

Question
Codons are part of the molecular structure of _____.
Answer
  • a protein
  • mRNA
  • tRNA
  • rRNA

Question 32

Question
What does it mean when we say the genetic code is redundant?
Answer
  • The genetic code is universal (the same for all organisms).
  • The genetic code is different for different domains of organisms.
  • A single codon can specify the addition of more than one amino acid.
  • More than one codon can specify the addition of the same amino acid.

Question 33

Question
Once researchers identified DNA as the unit of inheritance, they asked how information was transferred from the DNA in the nucleus to the site of protein synthesis in the cytoplasm. What is the mechanism of information transfer in eukarotes?
Answer
  • Messenger RNA is transcribed from a single gene and transfers information from the DNA in the nucleus to the cytoplasm, where protein synthesis takes place.
  • Proteins transfer information from the nucleus to the ribosome, where protein synthesis takes place.
  • Transfer RNA takes information from DNA directly to a ribosome, where protein synthesis takes place.
  • DNA from a single gene is replicated and transferred to the cytoplasm, where it serves as a template for protein synthesis.

Question 34

Question
According to the central dogma, what molecule should go in the blank? DNA → _____ → Proteins
Answer
  • mtDNA
  • mRNA
  • rRNA
  • tRNA

Question 35

Question
Codons are three-base sequences that specify the addition of a single amino acid. How do eukaryotic codons and prokaryotic codons compare?
Answer
  • Codons are a nearly universal language among all organisms.
  • Prokaryotic codons usually specify different amino acids than those of eukaryotes.
  • Prokaryotic codons usually contain different bases than those of eukaryotes.
  • The translation of codons is mediated by tRNAs in eukaryotes, but translation requires no intermediate molecules such as tRNAs in prokaryotes.

Question 36

Question
Which of the following occurs in prokaryotes but not in eukaryotes?
Answer
  • post-transcriptional splicing
  • concurrent transcription and translation
  • translation in the absence of a ribosome
  • gene regulation

Question 37

Question
Transcription in eukaryotes requires which of the following in addition to RNA polymerase?
Answer
  • ribosomes and tRNA
  • several transcription factors
  • aminoacyl-tRNA synthetase
  • start and stop codons

Question 38

Question
Which of the following best describes the significance of the TATA box in eukaryotic promoters?
Answer
  • Its significance has not yet been determined.
  • It sets the reading frame of the mRNA.
  • It is the recognition site for a specific transcription factor.
  • It is the recognition site for ribosomal binding.

Question 39

Question
A ribozyme is _____.
Answer
  • an enzyme that catalyzes the association between the large and small ribosomal subunits
  • an RNA with catalytic activity
  • a catalyst that uses RNA as a substrate
  • an enzyme that synthesizes RNA as part of the transcription process

Question 40

Question
Which of the following is the first event to take place in translation in eukaryotes?
Answer
  • the small subunit of the ribosome recognizes and attaches to the 5' cap of mRNA
  • covalent bonding between the first two amino acids
  • base pairing of activated methionine-tRNA to AUG of the messenger RNA
  • binding of the larger ribosomal subunit to smaller ribosomal subunits

Question 41

Question
A signal peptide _____.
Answer
  • terminates translation of messenger RNA
  • directs an mRNA molecule into the cisternal space of the ER
  • helps target a protein to the ER
  • signals the initiation of transcription

Question 42

Question
What must occur before a newly made polypeptide is secreted from a cell?
Answer
  • Its signal sequence must target it to the ER, after which it goes to the Golgi.
  • Its signal sequence must be cleaved off before the polypeptide can enter the ER.
  • Its signal sequence must target it to the plasma membrane, where it causes exocytosis.
  • It must be translated by a ribosome that remains free within the cytosol.

Question 43

Question
Translation requires _____.
Answer
  • mRNA, tRNA, DNA, and rRNA
  • mRNA, tRNA, and rRNA
  • mRNA, DNA, and rRNA
  • mRNA, tRNA, and DNA

Question 44

Question
During elongation, which site in the ribosome represents the location where a codon is being read?
Answer
  • P site
  • A site
  • E site
  • the small ribosomal subunit

Question 45

Question
Once a peptide bond has been formed between the amino acid attached to the tRNA in the P site and the amino acid associated with the tRNA in the A site, what occurs next?
Answer
  • translocation
  • initiation
  • reading of the next codon of mRNA
  • The codon-anticodon hydrogen bonds holding the tRNA in the A site are broken.

Question 46

Question
Which one of the following, if missing, would usually prevent translation from starting?
Answer
  • poly-A tail
  • exon
  • 5' cap
  • AUG codon

Question 47

Question
How does termination of translation take place?
Answer
  • The 5' cap is reached.
  • The end of the mRNA molecule is reached.
  • The poly-A tail is reached.
  • A stop codon is reached.

Question 48

Question
Post-translational modifications of proteins may include the _____.
Answer
  • addition of a 5 cap
  • addition of carbohydrates to form a glycoprotein
  • removal of introns
  • addition of a poly-A tail

Question 49

Question
A nonsense mutation in a gene _____.
Answer
  • has no effect on the amino acid sequence of the encoded protein
  • introduces a premature stop codon into the mRNA
  • alters the reading frame of the mRNA
  • changes an amino acid in the encoded protein

Question 50

Question
Which of the following DNA mutations is most likely to damage the protein it specifies?
Answer
  • an addition of three nucleotides
  • a base-pair deletion
  • a codon deletion
  • a substitution in the last base of a codon

Question 51

Question
Which of the following defines a genome?
Answer
  • the complete set of an organism's polypeptides
  • the complete set of a species' polypeptides
  • a karyotype
  • the complete set of an organism's genes and other DNA sequences

Question 52

Question
Asexual reproduction occurs during _____.
Answer
  • chromosome exchange between organisms of different species
  • fertilization
  • meiosis
  • mitosis

Question 53

Question
Which of the following is a true statement about sexual vs. asexual reproduction?
Answer
  • In sexual reproduction, individuals transmit half of their nuclear genes to each of their offspring.
  • In asexual reproduction, offspring are produced by fertilization without meiosis.
  • Asexual reproduction produces only haploid offspring.
  • Asexual reproduction, but not sexual reproduction, is characteristic of plants and fungi.

Question 54

Question
At which stage of mitosis are chromosomes usually photographed in the preparation of a karyotype?
Answer
  • metaphase
  • interphase
  • prophase
  • anaphase

Question 55

Question
Which of the following is true of a species that has a chromosome number of 2n = 16?
Answer
  • Each diploid cell has eight homologous pairs.
  • The species is diploid with 32 chromosomes per cell.
  • A gamete from this species has four chromosomes.
  • The species has 16 sets of chromosomes per cell.

Question 56

Question
Eukaryotic sexual life cycles show tremendous variation. Of the following elements, which do all sexual life cycles have in common? I. Alternation of generations II. Meiosis III. Fertilization IV. Gametes V. Spores
Answer
  • I, II, and IV
  • I, II, III, IV, and V
  • II, IV, and V
  • II, III, and IV

Question 57

Question
A given organism has 23 pairs of homologs in its karyotype. Therefore, we can conclude that it must _____.
Answer
  • be human
  • have gametes with 23 chromosomes
  • be an animal
  • reproduce sexually

Question 58

Question
Homologous chromosomes _____.
Answer
  • align on the metaphase plate in meiosis II
  • carry information for the same traits
  • carry the same alleles
  • are identical

Question 59

Question
If meiosis produces haploid cells, how is the diploid number restored for those organisms that spend most of their life cycle in the diploid state?
Answer
  • fertilization
  • reverse transcription
  • synapsis
  • DNA replication

Question 60

Question
The human X and Y chromosomes _____.
Answer
  • are called autosomes
  • include genes that determine an individual's sex
  • are both present in every somatic cell of males and females
  • are the same size and have the same number of genes

Question 61

Question
Which of these is a karyotype?
Answer
  • the appearance of an organism
  • organized images of a cells chromosomes
  • a display of a cells mitotic stages
  • a display of all of the cell types in an organism

Question 62

Question
The somatic cells of a privet shrub each contain 46 chromosomes. How do privet chromosomes differ from the chromosomes of humans ,who also have 46?
Answer
  • Privet shrubs must be metabolically more like animals than like other shrubs.
  • Genes of privet chromosomes are significantly different than those in humans.
  • Privet sex cells have chromosomes that can synapse with human chromosomes in the laboratory.
  • Privet cells cannot reproduce sexually.

Question 63

Question
After telophase I of meiosis, the chromosomal makeup of each daughter cell is _____.
Answer
  • haploid, and the chromosomes are each composed of two chromatids
  • diploid, and the chromosomes are each composed of a single chromatid
  • diploid, and the chromosomes are each composed of two chromatids
  • haploid, and the chromosomes are each composed of a single chromatid

Question 64

Question
Which of the following happens at the conclusion of meiosis I?
Answer
  • Four daughter cells are formed.
  • The chromosome number per cell remains the same.
  • Homologous chromosomes of a pair are separated from each other.
  • Sister chromatids are separated.

Question 65

Question
Which of the following can occur by the process of meiosis but not mitosis?
Answer
  • Diploid cells form haploid cells.
  • A diploid cell combines with a haploid cell.
  • Haploid cells fuse to form diploid cells.
  • Haploid cells multiply into more haploid cells.

Question 66

Question
Crossing over normally takes place during which of the following processes?
Answer
  • meiosis I
  • meiosis II
  • mitosis
  • mitosis and meiosis II

Question 67

Question
Homologous pairs of chromosomes align opposite of each other at the equator of a cell during _____.
Answer
  • meiosis metaphase II
  • meiosis metaphase I
  • meiosis telophase II
  • mitosis metaphase

Question 68

Question
Centromeres split and sister chromatids migrate to opposite poles in meiosis _____.
Answer
  • telophase I
  • anaphase I
  • telophase II
  • anaphase II

Question 69

Question
Independent assortment of chromosomes occurs during _____.
Answer
  • mitosis and meiosis II
  • meiosis I only
  • meiosis II only
  • mitosis and meiosis I

Question 70

Question
For a species with a haploid number of 23 chromosomes, how many different combinations of maternal and paternal chromosomes are possible for the gametes?
Answer
  • 23
  • about 1000
  • 46
  • about 8 million

Question 71

Question
Independent assortment of chromosomes is a result of _____.
Answer
  • the random combinations of eggs and sperm during fertilization
  • the random distribution of the sister chromatids to the two daughter cells during anaphase II
  • the random way each pair of homologous chromosomes lines up at the metaphase plate during meiosis I
  • the diverse combination of alleles that may be found within any given chromosome

Question 72

Question
When homologous chromosomes cross over, what occurs?
Answer
  • Maternal alleles are "corrected" to be like paternal alleles and vice versa.
  • Two chromatids get tangled, resulting in one re-sequencing its DNA.
  • Two sister chromatids exchange identical pieces of DNA.
  • Corresponding segments of non-sister chromatids are exchanged.

Question 73

Question
How is natural selection related to sexual reproduction as opposed to asexual reproduction?
Answer
  • Sexual reproduction results in the greatest number of new mutations.
  • Sexual reproduction allows the greatest number of offspring to be produced.
  • Sexual reproduction results in many new gene combinations, some of which will lead to differential reproduction.
  • Sexual reproduction utilizes far less energy than asexual reproduction.

Question 74

Question
The bulldog ant has a diploid number of two chromosomes. Therefore, following meiosis, each daughter cell will have a single chromosome. Diversity in this species may be generated by mutations and _____.
Answer
  • independent assortment
  • crossing over
  • nothing else
  • crossing over and independent assortment

Question 75

Question
The fastest way for organisms to adapt to a changing environment involves _____.
Answer
  • sexual reproduction
  • asexual reproduction
  • mutation

Question 76

Question
Which of the following is the meaning of the chromosome theory of inheritance as expressed in the early twentieth century?
Answer
  • Mendelian genes are at specific loci on the chromosome and, in turn, segregate during meiosis.
  • Individuals inherit particular chromosomes attached to genes.
  • No more than a single pair of chromosomes can be found in a healthy normal cell.
  • Natural selection acts on certain chromosome arrays rather than on genes.

Question 77

Question
Males are more often affected by sex-linked traits than females because _____.
Answer
  • X chromosomes in males generally have more mutations than X chromosomes in females
  • male hormones such as testosterone often alter the effects of mutations on the X chromosome
  • males are hemizygous for the X chromosome
  • female hormones such as estrogen often compensate for the effects of mutations on the X chromosome

Question 78

Question
SRY is best described as _____.
Answer
  • an autosomal gene that is required for the expression of genes on the Y chromosome
  • a gene region present on the Y chromosome that triggers male development
  • a gene present on the X chromosome that triggers female development
  • an autosomal gene that is required for the expression of genes on the X chromosome

Question 79

Question
In humans, clear gender differentiation occurs, not at fertilization, but after the second month of gestation. What is the first event of this differentiation?
Answer
  • formation of testosterone in male embryos
  • activation of SRY in male embryos and masculinization of the gonads
  • activation of SRY in females and feminization of the gonads
  • formation of estrogens in female embryos

Question 80

Question
All female mammals have one active X chromosome per cell instead of two. What causes this?
Answer
  • attachment of methyl (CH3) groups to the X chromosome that will remain active
  • activation of the BARR gene on one X chromosome, which then becomes inactive
  • inactivation of the XIST gene on the X chromosome derived from the male parent
  • activation of the XIST gene on the X chromosome that will become the Barr body

Question 81

Question
Pseudohypertrophic muscular dystrophy is a human disorder that causes gradual deterioration of the muscles. Only boys are affected, and they are always born to phenotypically normal parents. Due to the severity of the disease, the boys die in their teens. Is this disorder likely to be caused by a dominant or recessive allele? Is its inheritance sex-linked or autosomal?
Answer
  • incomplete dominant, sex-linked
  • recessive, sex-linked
  • recessive, autosomal
  • dominant, sex-linked

Question 82

Question
A recessive allele on the X chromosome is responsible for red-green color blindness in humans. A woman with normal vision whose father is color blind marries a color-blind male. What is the probability that this couple's first son will be color blind?
Answer
  • 3/4
  • 1/2
  • 1/4
  • 2/3

Question 83

Question
A man who carries an allele of an X-linked gene will pass it on to _____.
Answer
  • all of his sons
  • all of his daughters
  • half of his daughters
  • all of his children

Question 84

Question
Which of the following statements is true of linkage?
Answer
  • The closer two genes are on a chromosome, the lower the probability that a crossover will occur between them.
  • All of the traits that Mendel studied–seed color, pod shape, flower color, and others–are due to genes linked on the same chromosome.
  • Linked genes are found on different chromosomes.
  • The observed frequency of recombination of two genes that are far apart from each other has a maximum value of 100%.

Question 85

Question
Recombination between linked genes comes about for what reason?
Answer
  • Linked genes travel together at anaphase.
  • Independent assortment sometimes fails.
  • Nonrecombinant chromosomes break and then rejoin with one another.
  • Crossovers between these genes result in chromosomal exchange.

Question 86

Question
What is an adaptive advantage of recombination between linked genes?
Answer
  • New allele combinations are acted upon by natural selection.
  • Recombination must occur or genes will not assort independently.
  • Recombination is required for independent assortment.
  • The forces on the cell during meiosis II results in recombination.

Question 87

Question
What is the reason that closely linked genes are typically inherited together?
Answer
  • They are located close together on the same chromosome.
  • The number of genes in a cell is greater than the number of chromosomes.
  • Genes align that way during metaphase I of meiosis.
  • Alleles are paired together during meiosis.

Question 88

Question
One possible result of chromosomal breakage is for a fragment to join a nonhomologous chromosome. What is this alteration called?
Answer
  • duplication
  • deletion
  • inversion
  • translocation

Question 89

Question
A nonreciprocal crossover causes which of the following products?
Answer
  • nondisjunction
  • deletion only
  • deletion and duplication
  • duplication only

Question 90

Question
Abnormal chromosomes are frequently found in malignant tumors. Errors such as translocations may place a gene in close proximity to different control regions. Which of the following might then occur to make the cancer worse?
Answer
  • an increase in nondisjunction
  • failure of the cancer cells to multiply
  • expression of inappropriate gene products
  • a decrease in mitotic frequency

Question 91

Question
What is a syndrome?
Answer
  • a trait that leads to cancer at some stage in life
  • a specific characteristic that appears in conjunction with one specific aneuploidy
  • a characteristic facial appearance
  • a group of traits typically found in conjunction with a particular chromosomal aberration or gene mutation

Question 92

Question
Which of the following is known as a Philadelphia chromosome?
Answer
  • a human chromosome 9 that is found only in one type of cancer
  • a human chromosome 22 that has had a specific translocation
  • a chromosome found only in mitochondria
  • an animal chromosome found primarily in the mid-Atlantic area of the United States

Question 93

Question
Which of the following is an example of monosomy?
Answer
  • Klinefelter's syndrome
  • Turner's syndrome
  • trisomy X
  • Down syndrome

Question 94

Question
Genomic imprinting is generally due to the addition of methyl (CH3) groups to C nucleotides and chemical histone changes to silence a given gene. If this depends on the sex of the parent who transmits the gene, which of the following must be true?
Answer
  • The imprints are transmitted only to gamete-producing cells.
  • Genes required for early development stages must not be imprinted.
  • Methylation must be reversible in ovarian and testicular cells.
  • Methylation of this kind must occur more in males than in females.

Question 95

Question
Mitochondrial DNA is primarily involved in coding for proteins needed for protein complexes of the electron transport chain and ATP synthase. Therefore, mutations in mitochondrial genes would most affect _____.
Answer
  • DNA synthesis in cells of the immune system
  • the storage of urine in the urinary bladder
  • generation of ATP in muscle cells
  • the movement of oxygen into erythrocytes

Question 96

Question
Nothing in biology makes sense except in the light of evolution.
Answer
  • True
  • False

Question 97

Question
Intelligent design is a major driving force for biological understanding.
Answer
  • True
  • False

Question 98

Question
Eukaryotic Cells lack a nucleus.
Answer
  • True
  • False

Question 99

Question
ALL cells in eukaryotic organisms express the same genes.
Answer
  • True
  • False

Question 100

Question
The DNA sequence is more similar with common biological ancestors.
Answer
  • True
  • False
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