Question 1
Question
What is true about sarcomeres?
Answer
-
Extend from M to M line
-
The major protein of Z line sarcomeres is myosin
-
ContainsZline+1⁄2 Iband+Aband+1⁄2Iband+Zline
-
The major protein of the Z line of sacromere is creatines kinase
Question 2
Question
What is true about skeletal muscle?
Answer
-
T-tubuls are absent
-
Caveolas and gap junctions can be occasionally present
-
Actin-myosin binding is triggered by interaction of Ca2+ with troponin subunit C
-
Concentration triggered at motor end plate
-
Formed by structures called fibers
-
Skeletal muscle fibers are innervated by muscle neurons
Question 3
Question
What is true about perimysium?
Answer
-
It does not contain any blood vessels
-
It surrounds every single muscle fiber
-
It surrounds the whole muscle
-
It contains blood vessels
-
It surrounds a bundle of fibers
Question 4
Question
Which statement about skeletal muscle are correct?
Answer
-
Regeneration of skeletal muscles directly depends on amount of calcium ions
-
There are no sarcomeres in fibers
-
Skeletal muscle fibers are innervated by motor neurons
-
Are formed by structures called fibers
Question 5
Question
Which pair is correctly paired?
Answer
-
Simple cuboidal – lining ducts of most glands
-
Transitional – urinary bladder
-
Simple squamous – epidermis of skin
Question 6
Question
Which statement regarding nodal cilia is true?
Answer
-
Are associated with gastrulation
-
Are found in the embryo
-
Are arranged into 9 + 10 pattern
-
Are associated with rotational movement
Question 7
Question
In which type of junction occluding and claudin are characteristic and prominent?
Question 8
Question
What is true about mesenchyme?
Answer
-
Is called 4th germ layer
-
Is located between the mesenchyme and endoderm
-
Is located in mesoderm
-
Is one of three germ layers
-
Is located between the ectoderm and endoderm
-
Is derived from mesoderm
Question 9
Question
What is true about mesoderm?
Answer
-
Is one of the three germ layers
-
Is derived from mesenchyme
-
Is called 4th germ layer
-
Appears only during the prenatal life
-
Is located between the mesenchyme and endoderm
-
Is located above the ectoderm
Question 10
Question
What is true about so somitogenesis?
Answer
-
It happens before the initiation of neurolation
-
This is the process of segmentation of the paraxial mesoderm
-
Is regulated by the so-called segmentation and wave model
-
It occurs after the intitation of neurulation
-
It starts at the beginning of the 3rd week of prenatal life
-
It begins at the beginning of the 3rd month of prenatal life
Question 11
Question
Which statement regarding apical surface`s modification is correct?
Answer
-
Tight junction
-
Glycocalix
-
Goblet cell
-
Villus
Question 12
Question
Which of GAGs is/are characteristic for cartilage?
Answer
-
Keratin sulfate
-
Osteonectin
-
Hyaluronic acid
-
Dermatologist sulfate
Question 13
Question
What is true sclerotome?
Answer
-
Contains only epithelial like cells
-
Is derived from ventro-medial somite cells
-
Scelerotome gives rise to mesoderm
-
Contains secondary mesenchyme cells
Question 14
Question
What is true about somites?
Answer
-
They are blocks (segment) of the paraxial mesoderm
-
They are symmetrical structures
-
They are blocks (segment) of the lateral mesoderm
-
They are blocks (segment) of the visceral mesoderm
Question 15
Question
Which sentence/sentences is/are true?
Answer
-
Osteoclasts possess of the receptor for calcitonin
-
Inner fibrous layer of perichondrium contains chondrogenic cells
-
The precursors of osteoclasts are monocytes
-
Outer fibrous layer of perichondrium contains chondrogenic cells
Question 16
Question
Which feature regarding hyaline cartilage is correct?
Answer
-
Chondrocytes are grouped in isogenic groups
-
It is covered by perichondrium
-
Perichondrium is composed of two layers
-
Hyaline cartilage is highly vascularized
Question 17
Question
Which of the statements about woven bone is/are true?
Answer
-
Physiologically can be found in compact mature bone
-
Can be found in insertions of some tendon
-
In adult present in place of fracture repair
-
Possess lamellae
Question 18
Question
Which of the phrase/phrases concerning the perichondrium is/are true?
Answer
-
Is formed by collagen type II
-
Is responsible for appositional growth of cartilage
-
Acts protective for cartilage
-
Contains Sharpey fibers
Question 19
Question
Which cells of connective tissue promote the allergenic reactions?
Answer
-
Fibrocytes
-
Histiocytes
-
Fat cells
-
Mast cells
Question 20
Question
Which statement regarding connective tissue (CT) proper is true?
Answer
-
Is divided into loose and dense CTs
-
Collagen contains unusual amino acids desmosine and indodesmosine
-
Chondroblasts are main population of cells in the tissue
-
Transient cells of connective tissue are e.g fibroblasts
Question 21
Question
Which statement regarding adipose tissue is true?
Answer
-
There are two types, white uniocular and brown multilocular
-
Multiocular is rich in the human adult
-
Leptin is secretory product of white adipocytes
-
Brown adipose tissue changes into yellow one
Question 22
Question
What is the characteristic function of mast cells?
Answer
-
The surface contain receptor for IgE
-
Influence permeability of blood vessels
-
Participate in process of wound healing
-
Storing of chemical mediators in granules
Question 23
Question
What type of tissue is a tendon?
Question 24
Question
Which statement about holocrine glands is true?
Answer
-
Its example is sebaceous gland
-
The cells are often surrounded by myoepithelial cells
-
It’s example is mammary gland
-
The product of the cell is released with its apical part
Question 25
Question
Which of the sentence/s about cartilage is/are true?
Answer
-
Is avascular (without blood vessels) tissue
-
Ventral ends of the ribs are formed by hyaline cartilage
-
Ventral ends of the ribs are formed by fibrocartilage
-
Chondrogenic cells are the stem cells for chondroblasts
-
Epiphyseal plates are the hyaline cartilage structures needed for long bones growth
-
Hyaline cartilage form the temporal skeleton
-
Is well vascularized
Question 26
Question
Is it true that osteogenesis?
Answer
-
Is the bone development process
-
During intramembranous ossification the epiphyseal cartilages are formed
-
It could be said that bony collar formation is a kind of intramembranous ossification
-
Could happen thanks intramembranous ossification
Question 27
Question
Which sentence/s is/are true?
Answer
-
Haversian Canal is located in the periphery of the osteon
-
Inner fibrous layer of perichondrium contains chondrogenic cells
-
The precursors of osteoclasts are monocytes
-
Outer fibrous layer of perichondrium contains chondrogenic cells
Question 28
Question
Which of the phrase/s concerning osteoclasts are true?
Answer
-
Arises from monocytes
-
Produces cathepsin K
-
Pumping protons into resorption cavity of bone
-
Its projections form ruffled border
-
To its differentiation need RANKI
Question 29
Question
Which statement regarding connective tissue (CT) proper is true?
Answer
-
Is divided into loose and dense CTs
-
Fibroblasts can be differentiated into histiocytes
-
Cells of embryonic mesenchymal CT produce type I collagen fibers
Question 30
Question
What is the characteristic function of mast cells?
Answer
-
Influence permeability of blood vessels
-
Their histamine acts as an anticoagulant
-
Synthesis of IgE
-
They can produce elastic fibers
-
The surface contains receptors for IgE
-
Storing chemical mediators in granules
Question 31
Question
Which features are characteristic for multilocular adipose tissue?
Question 32
Question
Which type of tissue is tendon?
Question 33
Question
Which statement regarding synthesis of collagen fibers are correct?
Answer
-
Hydroxylation of proline and lysine is within extracellular environment
-
Glycosylation of hydroxylysine is within extracellular environment
-
Procollagen is precursor for tropocollagen
-
Hydroxylation of proline and lysine is within intracellular environment
-
Co-factors; O2, Fe, vit. C are needed for the hydroxylation of proline and lysine
Question 34
Question
What is true about somites?
Answer
-
They develop from the cranial towards the caudal region
-
They are blocks (segments) of the paraxial mesoderm
-
None of them disappear
-
They appear between the 20th and 35th day of prenatal life
Question 35
Question
What is true about the dermatome?
Answer
-
Is a structure located closer to the ectoderm in developing embryo
-
It will soon contribute to the development of the skeletal muscles
-
Dermatome progenitors together with cells from the lateral mesoderm will form an epidermis
-
Dermatome cells are differentiated from dermomyotome
-
Is the structure located closer to the neural tube in embryo
-
Dermatome progenitors together with cells from the lateral mesoderm will form a dermis
-
Dermatome cells are differentiated from myotome
Question 36
Question
What is true about perimysium?
Answer
-
It surrounds every single muscle fiber
-
It surrounds the whole muscle
-
It does not contain any blood vessels
-
It contains blood vessels
-
It surrounds a bundle of fibers
Question 37
Question
What is true about sarcomeres?
Answer
-
Contains Z line + 1/2 I band + A band + ½ I band + Z line
-
Are typical for smooth muscle
-
In smooth muscle sarcomeres are arranged in myofibrils
-
Are present only in smooth muscles
Question 38
Question
Which statements about skeletal muscles are correct?
Answer
-
Skeletal muscles contain diads
-
Sarcomeres is a segment of myofibril between two Z lines.
-
Dark stained band is called the I band
-
Are formed by structures called fibers
-
Actin-myosin binding is triggered by interaction of Ca2+ with troponin subunit C
-
Phosphorylation of MLCK is responsible for binding actin and myosin
-
T-tubules are present in the center of the triads
-
T-tubules are absent
Question 39
Question
What is true about the dermamyotome?
Answer
-
It is a ventro-medial part of the somite
-
Is also called lateral mesoderm
-
It is a dorsolateral part of the somite
-
Its cells can’t migrate
Question 40
Question
What is true about skeletal muscle contraction?
Answer
-
During the skeletal muscles contraction sarkomeres retain their original length
-
During the skeletal muscles contraction energy is released from ATP
-
During the skeletal muscles contraction calcium ions bind to the calmodulin
-
To trigger a muscle contraction, calcium has to bind to myosin in smooth, skeletal and cardiac muscle cells
Question 41
Question
Which statement regarding glands is correct?
Answer
-
Goblet cell is a unicellular gland
-
Holocrine is sebaceous gland
-
Salivary glands are always seromucous
-
Exocrine derive from the epithelium
Question 42
Question
Which features are typical for epithelium/epithelial cells?
Question 43
Question
Which statement about holocrine secretion is true?
Answer
-
It is also called merocrine secretion
-
It is characteristic for the sebaceous glands
-
It consists in turning the entire cell into secretion and its excretion
-
It is characteristic for the salivary gland
Question 44
Question
Which of cells are located in connective tissue do originate from the bone marrow?
Answer
-
Mast cells
-
Adipocytes
-
Fibrocytes
-
Histiocytes
Question 45
Question
Which cells can produce extracellular matrix?
Answer
-
Histiocytes
-
Lymphoblasts
-
Fibrocytes
-
Fibroblasts
Question 46
Question
Which intercellular junctions are included to anchoring (adherens) junctions?
Answer
-
Adherens junction
-
Desmosome
-
Hemidesmosome
-
Occludens
Question 47
Question
Which statement regarding hemidesmosomes is correct?
Question 48
Question
What is Volkmann canal?
Answer
-
It is located in lacunae
-
It connects two Haversian canals
-
It is located in the center of osteon
-
It connects canaliculi with osteocytes
Question 49
Question
Is it true that the bone?
Answer
-
osteoblasts are polarized cells
-
ECM is high mineralized
-
Osteoblast liberate osteoclasts activating protein (OPG), RANKL and M-CSF
-
Periosteum is similarly built as endosteum
-
Osteoblast control metabolism of osteoclast
-
Osteoblast control the number of osteoclast
-
Ruffled border of osteoclast is situated at the resorption cavity of bone
-
The metabolism is under hormonal control
-
Water constitutes up to 80% of the weight of fresh tissue
Question 50
Question
Which pair: Cell of the mononuclear phagocyte system - location is correct?
Answer
-
blood – monocyte
-
liver - kupffer cell
-
brain - kupffer cell
-
spleen - kupffer cell
Question 51
Question
Which feature is characteristic for elaunin fibers?
Question 52
Question
Which cells of the connective tissue are classificated as residental cells?
Answer
-
Fibroblasts
-
Fibrocytes
-
Adipocytes
-
Mesenchymal cells
-
Adult stem cells
-
Fixed macrophages
Question 53
Question
What is true about the somitomers?
Answer
-
Appear around 3rd week of perinatal life
-
Are located on one side along the neural tube
-
Somitomeres are involved in the segmentation of the neutral plaque, the production of neuromeres
-
Are located below the occipital region of the head
-
Consists of mesodermal cells, arranged in concentric coils around their own center
Question 54
Question
What is true about endomysium?
Answer
-
Surrounds the whole muscle
-
Is located between perimysium and epimysium
-
Is delicate, reticular connective tissue.
-
Large, major nerves supply this sheath
-
Surround the external lamina of individual muscle fibers
-
Surrounds the entire muscle
-
Capilarries form a rich network within the endomysium
Question 55
Question
What is true about troponin?
Answer
-
Is a complex of 3 subunits
-
Is attached to tropomyosin
-
Troponin C can bind calcium ions
-
Is the main component of the Z line of sarcomere
-
Is attached to Z line
Question 56
Question
What is true about the cardiac muscle (CM)?
Answer
-
Contraction is triggered at nodes of conducting fibers
-
Nuclei are centrally located
-
Contraction is triggered at motor end plate
-
Fibers are aligned in branching arrangements
Question 57
Question
Which pairs are correct (cells/structures and their location)?
Answer
-
Caveolae - Smooth muscle
-
Intercalated discs - cardiac muscle
-
Smooth muscle cells - muscularis externa of small intestines
-
Two terminal cisterns per sarcomere with T-tubule - skeletal muscle
Question 58
Question
Which statement regarding transitional epithelium is true?
Answer
-
Is simple columnar epithelium
-
Is not located on a basal lamina
-
Changes its form according to the degree of distention
-
Is present in urinary bladder
-
Is stratified cuboidal/columnar epithelium
-
Is located on basal lamina
-
Umbrella cells are dedicated to protect other cells against hypertonic urine
-
Is also called urothelium
-
In some areas of the umbrella cells special protective protein called uroplakin is present
-
Superficial cells may be binucleated
Question 59
Question
Which statement regarding transitional epithelium is true?
Answer
-
Is covering minor and major calyces
-
Its dome-shaped umbrella cells can change morphology to become flattened
-
Includes basal cells, intermediate cells with one to several layers of cells and superficial umbrella cells
Question 60
Question
Which statement regarding primary cilia is true?
Answer
-
Are associated with gastrulation
-
Are associated with passive movement
-
are associated with active movement
-
Are arranged into 9+0 pattern
-
Are arranged into 9+2 pattern
-
Are only found in the embryo
Question 61
Question
Which proteins form desmosomes?
Answer
-
Cadherins
-
Desmogleins
-
Desmocollins
-
Armadillo
-
Plakophilins
-
Plakoglobin
-
Desmoplakin
Question 62
Question
What is true about the dermomyotome?
Answer
-
Is so called lateral mesoderm
-
Is so called paraxial mesoderm
-
It is a dorsolateral part of the somite
-
Will differentiate into a myotome and dermatome
-
It’s created after separation of myotome and dermatome
-
Its cells can migrate
-
Its cells can’t migrate
Question 63
Question
Which connection: cells - place of presence, is correct?
Answer
-
Astrocytes - peripheral nervous system
-
Ependymocytes - central nervous system
-
Ependymocytes - peripheral nervous system
-
Ependymocytes - central canal
Question 64
Question
Which statement regarding ganglia is true?
Answer
-
Multipolar neurons are present in autonomic ganglia
-
Are composed of both - perikaryons and nerve fibers
-
Sensory ganglia are surrounded by connective tissue capsule
-
Multipolar neurons are present in sensory ganglia
Question 65
Question
Is it true that tracheoesophageal Fistula (TEF)?
Answer
-
In other words, it is respiratory distress syndrom (RDS)
-
Is often accompanied by esophageal atresia (EA)
-
Is result of incomplete separation of foregut into the digestive and respiratory system
-
In other words, it is hyaline membrane disease
Question 66
Question
Which statement about lung development is correct?
Answer
-
Primary bronchi buds appear at the beginning of the 5th week of prenatal development
-
Some of the bronchial tree branching are made after birth
-
Cranial lung’s lobes develop earlier/faster than caudal
Question 67
Question
Which statement about the development stages of the respiratory system is true?
Answer
-
Canalicular stage in the first stage
-
Primary septa are thicker than secondary alveolar septa
-
The respiration of featus is possible during pseudoglandular stage
-
Alveolar stage is finished during the first years of postnatal life
Question 68
Question
Does conducting portion of respiratory system inculde?
Answer
-
Respiratory
-
Alveoli
-
Trachea
-
Nasal cavities
Question 69
Question
Which answer/s regarding the respiratory system is/are true?
Answer
-
Respiratory epithelium contains ciliated cells
-
Nasal cavity is part of respiratory portion
-
Includes system of tubes that link the site of gas exchanging with external environment
-
Includes paired lung
Question 70
Question
Does respiratory portion of respiratory system include?:
Answer
-
Olfactory epithelium
-
Oral cavity
-
Alveolar ducts
-
Respiratory bronchioles
Question 71
Question
Which organs of the lymphatic system are capsulated (covered by capsule)?
Answer
-
Bone marrow
-
BALT
-
Spleen
-
Thymus
Question 72
Question
Which statement regarding adaptive immunity is true?
Answer
-
Includes antigen-presenting cells
-
Its response is very rapid
-
One of its example is low pH of gastric juice
-
It includes action of B lymphocytes
Question 73
Question
Which statement regarding adaptive immunity is correct?
Answer
-
Is evolutionarily older than aquired immunity
-
Is because of phagocytic activity of neutrophils
-
Is because of clonal expansion of B cells
-
Includes action of B lymphocytes
Question 74
Question
When does the spleen begin to develop?
Answer
-
At the end of 5th month of prenatal life
-
At the end of 3rd week of prenatal life
-
At the end of 7th week of prenatal life
-
At the end of 5th week of prenatal life
Question 75
Question
What is the main origin of lymph node?
Answer
-
Neuroectoderm
-
Mesenchyme
-
Endoderm
-
Mesoderm
Question 76
Question
From which pouch a thymus arises?
Question 77
Question
Which of the following statements about maturation of granulocytes is/are true?
Answer
-
Stages of granulocyte maturation in proper order: promyelocyte & myeloblast & myelocyte & metamyelocyte
-
Involves ejecting of the nucleus
-
Stages of granulocyte maturation in proper order: myeloblast & promyelocyte & metamyelocyte & myelocyte
-
Involves changing of the shape of the nucleus
Question 78
Question
Which stage is the first stage of nondividing cells during erythropoiesis?
Question 79
Question
What is true about hematopoietic stem cells?
Answer
-
Are able to response for a growth factors stimulation
-
Their morphology is similar to lymphocytes
-
They have typical morphological features
-
All blood cells are derived from one hematopoietic stem cell
Question 80
Question
Which molecules are permissive for neural crest cells migration?
Question 81
Question
What is true about the cranial neural crest?
Answer
-
They leave the future brain after the closure of the neural folds
-
they migrate toward the gut
-
They differentiate into cells and tissues that constitute much of soft and hard tissues of the face
-
They leave the future brain well before closure of the neural crest.
Question 82
Question
What is true about neural crest?
Answer
-
The neural crest originates from cells located along the lateral margins of the neural palate
-
neural crest cells arise as the result of an inductive action by non-neural ectoderm
-
neural crest cells arise as the result of an inductive action by neuroectoderm
-
the neural crest originates from the mesoderm
Question 83
Question
Which statement regarding impulse conducting system of the heart is correct?
Answer
-
Atrioventricular node is its part
-
It is involved in controlling of the contraction of the myocardium
-
subendocardial conducting network is part of it
-
Atrioventricular bundle (of His) is its part
Question 84
Question
Which statement regarding discontinuous capillaries is true?
Answer
-
They have many tight, occludin junctions between endothelial cells
-
They have large fenestrations within basal lamina
-
They are found in the muscles
-
They are characteristic for bone marrow
Question 85
Question
Which statement regarding endothelium is correct?
Answer
-
It is simple squamous epithelium
-
There is no endothelium in wall of veins
-
it can be found in the intima of artery
-
Endothelial cells are metabolic active cells
Question 86
Question
Which statement(s) regarding the leukocytes is correct?
Answer
-
Basophils have biconcave shape
-
Monocytes differentiate into macrophages
-
Basophils have kidney-shaped nucleus
-
Monocytes contain azurophilic granules
Question 87
Question
Which of the following statements about erythrocytes is/are true?
Answer
-
Can leave the blood vessels by Diapedesis
-
Are called red blood cells
-
Their shape is maintained by a special cytoskeleton
-
Transport oxygen and carbon dioxide
Question 88
Question
Which is true about the bone marrow?
Answer
-
Red bone marrow is not hematogenous
-
In adult hemopoiesis takes place in red bone marrow
-
Great number of adipose cells are present in yellow bone marrow
-
Red bone marrow is present in flat bones and vertebrae
Question 89
Question
Which statement regarding skin is correct?
Answer
-
Keratinocytes are main population of dermis
-
SALT system includes keratinocytes, T lymphocytes and Langerhans cells
-
Eccrine and apocrine sweat glands release its secretion by a merocrine process
-
Keratinocytes are main population of hypodermis
Question 90
Question
In which layer of the epidermis desmosomes are present in the highest number?
Question 91
Question
Which gland releases its secretion by holocrine way?
Answer
-
Liver
-
Sebaceous gland
-
Salivary gland
-
Gall bladder