Neuro Pharmacology - Schizophrenia

Description

Schizophrenia
Ifeoma Okekearu
Quiz by Ifeoma Okekearu, updated more than 1 year ago
Ifeoma Okekearu
Created by Ifeoma Okekearu over 9 years ago
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Resource summary

Question 1

Question
What are the criteria for a schizophrenia diagnosis?
Answer
  • Positive Schizophrenic Symptoms
  • Disorganized Speech/ Thoughts
  • Negative Schizophrenic Symptoms
  • Symptoms lasting > 6 months
  • All of the choices are correct

Question 2

Question
Most cognitive symptoms in schizophrenia are correlated with dysfunctions of the mesolimbic system.
Answer
  • True
  • False

Question 3

Question
Which of the following are structural abnormalites are found in the brians of schizophrenic patients.
Answer
  • Lateral and Third Ventricular Enlargement
  • Volume Increases of the Prefrontal and Oribitofrontal Cortex
  • Abnormalities of the Basal Ganglia
  • Volume Reduction of the Temporal Lobe

Question 4

Question
NMDA Glutamate receptor activation will produce "schizophrenia-like" symptoms in healthy adults.
Answer
  • True
  • False

Question 5

Question
Select all of the statements that are prodromal signs/symptoms of schizophrenia.
Answer
  • Sudden development of interest in abstract ideas.
  • Decline is occupational and interpersonal functioning.
  • Quiet, passive, introverted personality
  • Delusions and Hallucinations

Question 6

Question
Schizophrenia is sa neurodegenerative disorder
Answer
  • True
  • False

Question 7

Question
Architectural changes are often involved in certain regions of the brains of schizophrenic patients. These same regions become vey active during episodes of hallucination. Which regions below would an MRI show activity during a hallucination?
Answer
  • Temporal Lobe
  • Prefrontal Cortex
  • Occipital Lobe
  • Parietal Lobe
  • Hippocampus

Question 8

Question
Select the statement(s) below that is/are involved in the manifestations of schizophrenic symptoms.
Answer
  • Schizophrenia patients usually have over-activity of the dopamine D2 receptors.
  • 5-HT2A Receptors are involved in the pathogenesis of schizophrenia
  • Blockage of NMDA glutamate mimic all schizophrenic symptoms suggesting schizophrenic patients have a deficiency in these receptors.
  • All of the above
  • None of the above

Question 9

Question
NMDA receptors require multiple stimuli to converge in order for them to become activated.
Answer
  • True
  • False

Question 10

Question
Which statement about the glutaminergic hypothesis of schizophrenia is true?
Answer
  • There is hyperactivity of the mesolimbic system and hypoactivity of the mesocortical system.
  • There is hypoactivity of the mesolimbic system and hypoactivity of the mesocortical system.
  • There is hyperactivity of the mesolimbic system and hyper activity of the mesocortical system.
  • There is hypoactivity of the mesolimbic system and hyperactivity of the mesocortical system.

Question 11

Question
What effect would blockage of the dopamine D2 receptors in the CTZ have on a patient?
Answer
  • Parkinsonism
  • Tardive Dyskinesia
  • Anti-Emetic
  • Hypothermia
  • None of the above

Question 12

Question
Which option below would NOT be a side effect of the use anticholinergics?
Answer
  • Nausea
  • Tachycardia
  • Constipation
  • Blurry Vision

Question 13

Question
What is the course of action for the treatment of a psychotic patient that develops the rare Neuroleptic Malignant Syndrome
Answer
  • Stop Anti-Psychotic drug, IV Dantrolene, IV Normal Saline, & Bromocriptine
  • Increase Anti-Psychotic drug, PO Dantrolene, Heating Pads, Diphenhydramine
  • Stop Antipsychotic, Injected Diazepam, IV Fluids, Inject Bromocriptine
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