3594007
Description
Quiz by Ifeoma Okekearu, updated more than 1 year ago
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Created by Ifeoma Okekearu
about 9 years ago
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Question 1
Question
Activation of the thalamus can activate the innate fear pathway. Without the collaboration of the prefrontal cortex, this activation can lead to fear manifestations without a source.
Answer
- True
- False
Question 2
Question
Which of the following statements about the manifestation of anxiety/fear symptoms is not true?
Answer
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Lesions of the medical prefrontal cortex increases the risk for anxiety.
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Inhibition of the orbitofrontal cortex leads to the hyperactivity of the amygdala in the presence of a potential threat which produces fear responses.
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In the innate fear response, the thalamus is activated by the amygdala with sequential prefrontal cortex activation leading to the fear manifestation.
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The amygdala mediates key functions in the processing of fear and threat-related information.
Question 3
Question
Select all of the options that are effective in the treatment of anxiety disorder
Answer
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Relaxation Training
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Systematic Desensitization
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Group Therapy
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Pharmacotherapy
Question 4
Question
Select the statements about the tuberomamillary nucleus that are true
Answer
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It is inhibited by GABA from the ventrolateral pre optic area.
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It is activated by glutamate
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It is inhibited by orexin
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Histamine promotes calm wakefulness through H2 receptors
Question 5
Question
Where to benzodiazepines bind and what is their mechanism of action?
Answer
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They bind to a niche between the α and γ subunits of the GABAa receptors behaving as GABA agonist
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They bing to the niche between the α and γ subunits of the GABAb receptors acting as a positive allosteric modulator
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They bind to a niche between the α and γ subunits of the GABAa receptors behaving as positive allosteric modulators
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They bing to the niche between the α and γ subunits of the GABAb receptors acting as a GABA agonist
Question 6
Question
Positive modulation of the GABAa receptors of the amygdala will produce a hypnotic effect
Answer
- True
- False
Question 7
Question
Flumenazil is a GABA antaagonist
Answer
- True
- False
Question 8
Question
Which anti-xiolitic(s) would be a good choice for an elderly patient?
Answer
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Lorazepam
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Temazepam
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Diazepam
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Chlordiazepoxide
Question 9
Question
Drugs binding to α1, α2, α3, α5, and γ subunits of the GABAa synaptic receptor mediate phasic inhibition triggered by peak concentrations of GABA predisposing users to dependence.
Answer
- True
- False
Question 10
Question
What is the recommended rate of reduction for people wanting to discontinue the use of benzodiazepines?
Answer
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Stop immediately and drink a lot of water
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Flumenazil injections over the course of 5-7 days
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Decrease by 10 percent each day
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None of the above responses are correct
Question 11
Question
Barbiturates produce an anti-xiolitic effect by binding to the β subunit of the GABA-a receptor. At high concentrations, they can mimic GABA and directly activate chloride channels.
Answer
- True
- False
Question 12
Question
Overdose of barbiturates can lead to death due to respiratory and cardiac depression and the lack of an effective antagonist.
Answer
- True
- False
Question 13
Question
Monoamine Oxidase Inhibitors are Indicated for use with Barbiturates because they shorten the length of action, decreasing side effects.
Answer
- True
- False
Question 14
Question
What statement below is accurate regarding the changes the amounts of BDNF in the brain of depressed patients?
Answer
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There is an INCREASE in the amount of BDNF in the Hippocampus and a DECREASE in the amount of BDNF in the Nucleus Accumbens
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There is an INCREASE in the amount of BDNF in BOTH the Hippocampus and the Nucleus Accumbens.
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There is a DECREASE in the amount of BDNF in BOTH the Hippocampus and the Nucleus Accumbens.
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There is a DECREASE in the amount of BDNF in the Hippocampus and an INCREASE in the amount of BDNF in the Nucleus Accumbens.
Question 15
Question
Which class of anti-depressants cause the "Cheese Effect"
Answer
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MAOIs
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SSRIs
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NMDA Blockers
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SNRIs
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