Melatonin is produced by which of the following pathways.
Substances:
1.Serotonin
2.Melatonin
3.L-Tryptophan
4.N-Acetyl Serotonin
5.5-HTP
Enzymes:
A.tryptophan 5-hydroxylase
B.acetylserotonin O-methyltransferase
C.AANAT
D.5-HTP decarboxylase
Answer
1B4D2A3C5
3A5D1C4B2
3A1C5D4B2
1B4D3C2A5
Question 3
Question
Bioavailability and Half-Life of Melatonin
Answer
30-50% and 30-50 Minutes.
40-60% and 20 to 30 Minutes.
15-25% and 60 to 90 Minutes.
60-80% and 90 to 120 Minutes.
Question 4
Question
Melatonin is regulated by Norepinephrine by which pathway:
Substance:
1.Norepinephrine
Enzyme:
A.PKA
B.AANAT
Receptor:
a.Beta Adrenergic
Answer
1aBA
Ba1A
AB1a
1aAB
Question 5
Question
Light of which of the following wavelength criteria will not inhibit melatonin
Answer
Under 530 nm.
Over 480 nm.
Over 530 nm.
Under 480 nm.
Question 6
Question
Dopamine plays a role in Melatonin secretion by:
Answer
Providing negative feedback to Melatonin formation.
Upregulating Melatonin receptors.
Enhancing the effects of Norepinephrine on Melatonin secretion.
Increasing in response to Melatonin binding with receptors.
Question 7
Question
5HT has which of the following functions and changes:
Answer
It decreases Serotonin production.
It is decreased by AANAT to be converted to Melatonin.
It is produced only during the day.
Its production leads to increased sympathetic activity and receptor activation on the pineal gland, ultimately leading to decreased Melatonin synthesis.
Dopamine activation of the D4 receptor heteromeres decreases 5HT in the morning.
Question 8
Question
The Pineal Gland is located outside of the blood brain barrier.