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pharma ( mid year )

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atbaa2020asu
Quiz by atbaa2020asu, updated more than 1 year ago
atbaa2020asu
Created by atbaa2020asu almost 9 years ago
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Question 1

Question
1-the following may be used to assess drug efficacy in the graded dose – response curve :
Answer
  • A- slope of the curve
  • B- ED50
  • c- Emax
  • D- A&C

Question 2

Question
2-atropine is used as pre-anesthetic medication due to all the following except :
Answer
  • it decreases blood pressure
  • it induces bronchodilatation & stimulates respiration
  • it decreases vomiting
  • it blocks the cardiac muscarinic receptors

Question 3

Question
3- the following is NOT an adverse effect of cholinomimetics :
Answer
  • Bronchospasm
  • Diarrhea
  • Tachycardia
  • aggravate peptic ulcer

Question 4

Question
4-treatment of atropine poisoning does not include:
Answer
  • A- gastric lavage
  • B- neostigmine
  • C- diazepam
  • D- cooling blankets

Question 5

Question
5-Important factor\s which may govern diffusion of drugs across cell membranes :
Answer
  • A- pKa value of the drug.
  • B- pH of the medium.
  • C- lipid solubility of the drug.
  • D- all of the above.

Question 6

Question
6- at the end of operation , the action of neuromuscular blocker is reversed by :
Answer
  • a- atropine preceded by neostigmine
  • b- neostigmine preceded by atropine
  • c- atropine preceded by physostigmine
  • d- physostigmine preceded by atropine

Question 7

Question
7-clearance is useful in calculation of :
Answer
  • a-maintenance doce
  • b-loading dose
  • c- t 1\2
  • d -a&c

Question 8

Question
8-Propranolol is contraindicated in all of the following cases except:
Answer
  • A) Open angle glucoma
  • B) Diabetes Mellitus
  • C) Thyrotoxicosis
  • D) Bronchial asthma

Question 9

Question
9-which of the following beta blockers is suitable in patient with open angle glaucoma ?
Answer
  • a- betoxolol
  • b- bisorolol
  • c- pindolol
  • propranolol

Question 10

Question
10- Which of the following drugs inhibit the release of NE :
Answer
  • A) Guanethedine
  • B) Reserpine
  • C) Metyrosine
  • D) Non of the above

Question 11

Question
11- patient with history of sulfonamide hypersesitivity , suffered head injury with brain edema , which of the following combinations is best for him ?
Answer
  • a- acetazolamide & mannitol
  • b- metolazone & mannitol
  • c- dexamethazone & frusemide
  • d- dexamethazone & mannitol

Question 12

Question
12- furosemide is useful for treatment of the following conditions except :
Answer
  • a-hypercalcuria
  • b- hypertensive encephalopathy
  • c- acute renal failure
  • d- acute pulmonary edema

Question 13

Question
13-antihypertensive effect of frusemide is decreased by :
Answer
  • a- NSAIDs
  • b- spironolactone
  • c- corticosteroids
  • d- a& c

Question 14

Question
14-The following diuretics are secreted through the renal tubules except:
Answer
  • a- Triamterene
  • b- Spironolactone
  • c-Hydrochlorothiazide
  • d- Frusemide

Question 15

Question
15- uses of acetazolamide include all the following except :
Answer
  • a- urinary calcium phosphate stones
  • b- emphysema & high altitude sickness
  • c- to alkalinize urine for excretion of salicylates
  • d- to alkalinize urine for excretion of barbiturates

Question 16

Question
16- ACEIs have the following advantages except :
Answer
  • a- they induce no change in heart rate
  • b- they preserve renal function
  • c- they induce no change in k level
  • d- they reduce cardiovascular mortality

Question 17

Question
17- A nitric oxide donor that may induce cyanide toxicity :
Answer
  • a- nitrates
  • b- nitroprusside
  • c- nicardipine
  • d- A&B

Question 18

Question
18- A hypertensive patient with angina should not be given :
Answer
  • a-pindolol
  • b- bisoprolol
  • c- amlodipine
  • d- metoprolol

Question 19

Question
19- used with vasodilators to counteract the reflex tachycardia :
Answer
  • a- captopril
  • b- methyldopa
  • c- bisoprolol
  • d- pindolol

Question 20

Question
20- in congestive heart failure , the following drugs act directly on the myocardium increasing the cardic output except :
Answer
  • a- captopril
  • b- digoxin
  • c- dopamine
  • d- dobutamine

Question 21

Question
21-A drug used to terminate an attack of paroxysmal supraventricular tachycardia but may induce bronchospasm :
Answer
  • a- lidocaine
  • b-adenosine
  • c- verapamil
  • d- diltiazem

Question 22

Question
22- all the following decrease mortality in HF except :
Answer
  • a- metoprolol
  • b-bisoprolol
  • c- carvedilol
  • d- pindolol

Question 23

Question
23-A pregnant asthmatic hypertensive patient should NOT receive :
Answer
  • a- candesartan
  • b- labetalol
  • c- thiazides
  • d- all the above

Question 24

Question
24- In management of digitalis induced bradyarrhythmia the following is (are) true :
Answer
  • a- KCL should not be administered
  • b- atropine should be administered
  • c- lidocaine should be administered
  • d- A&B

Question 25

Question
25- candesartan has the following advantages over lisinopril EXCEPT :
Answer
  • a- no bradykinin production thus no risk of cough
  • b- antagonizes AG II formed by ACE & non- ACE pathways
  • c- no hormonal "escape " seen with prolonged ACEIs therapy
  • d- less teratogenic

Question 26

Question
26- which one of the following is adirect inhibitor of factor Xa ?
Answer
  • a- dalteparin
  • b- heparin
  • c- rivaroxaban
  • d- fondaparinux

Question 27

Question
27- all the following decrease the action of warfarin except :
Answer
  • a- erythromycin
  • b- vit K
  • c- oral contraceptives
  • d- rifampicin

Question 28

Question
28- which of the following is long acting & can be given by single I.V bolus :
Answer
  • a- streptokinase
  • b- tenecteplase
  • c- urokinase
  • d- all of the above

Question 29

Question
29- folic acid deficiency is associated with the use of :
Answer
  • a- methotrexate
  • b- trimethoprim
  • c- metronidazole
  • d- A&B

Question 30

Question
30- given that normal Hb=14gm/ dl , which of the following the following is the parentral iron dose required to correct anemia & replenish stores for a female with Hb=4 gm / dl :
Answer
  • a- 100 gm
  • b- 10 gm
  • c- 5 gm
  • d- 2.5 gm
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