Question 1
Question
What defines Non-Megaloblastic Anaemia?
Question 2
Question
In Melagoblasic Anaemia, other blood cells are likely to be affected
Question 3
Question
Liver disease and alcohol cause what type of anaemia?p
Question 4
Question
Which of the following is not a cause of Melagoblastic Anaemia?
Answer
-
HIV treatment
-
B12 deficiency
-
Iron deficiency
-
Folate deficiency
Question 5
Question
Pancytopaenia- a reduction of all three blood components
Question 6
Question
Why is pancytopaenia a symptom of Megaloblastic anaemia?
Answer
-
Cells apoptose due to DNA synthesis failure
-
Cells cannot be produced due to crowded bone marrow
-
Cells die because of insufficient folate
Question 7
Question
Megaloblastic anaemia leads to a shorter cell lifespan
Question 8
Question
Megaloblastic anaemia has an Inc MCV but Dec RDW
Question 9
Question
Erythrocyte precursors with retarded nuclear maturation
Answer
-
Megaloblasts
-
Oval Macrocytes
-
RBC fragments
Question 10
Question
Oval macrocytes -> larger reiculocytes ->
Answer
-
Larger R.B.C's
-
Smaller R.B.C's
-
Fragmented R.B.C's
Question 11
Question
In M.M.A, cells are less fragile and cannot be broken down, so they accumulate in the blood
Question 12
Question
Which of the following are symptoms of M.M.A?
Question 13
Question
Which of the following are results of EXTREME B12/Folate deficiency?
Answer
-
Dementia
-
Neuropathy
-
Jaundice
Question 14
Question
What is the role of B12?
Question 15
Question
B12 is only synthesised in micro-organisms
Question 16
Question
Where is B12 stored?
Answer
-
The liver
-
The kidneys
-
The spleen
Question 17
Question
GI diseases, tapeworm and a lack of intrinsic factor all cause what?
Question 18
Question
Transcabalmin II (TCII) deficiency can be tested for
Question 19
Question
Folate is very sensitive to cooking and will degrade easily
Question 20
Question
How long will the liver stores of folate last?
Question 21
Question
Pregnancy and chronic haemolytic conditions cause what?
Answer
-
Inc Folate requirement
-
Inadequate folate intake
-
Folate malabsorption
Question 22
Question
Folate deficiency can be drug induced
Question 23
Question
Folate is vital for rapidly dividing cells
Question 24
Question
Folate deficiency can cause....