BioChemistry Quiz

Description

Get ready to get Rekt.
Roy Hove
Quiz by Roy Hove, updated more than 1 year ago
Roy Hove
Created by Roy Hove over 8 years ago
62
1

Resource summary

Question 1

Question
L’acide phosphorique est tri-basique, avec des valeurs de pKa de 2.14, 6.88 et 12.4. Quelle forme ionique est prédominante à pH = 5.9 ?
Answer
  • H3PO4
  • H2PO4-
  • HPO42-
  • PO43-

Question 2

Question
What is the basic formula of Carbohydrates?
Answer
  • Cn(OH)n
  • Cn(CO2)n
  • Cn(H2O)n
  • C(H2O)n

Question 3

Question
Which of these is not these is not a polysaccharide?
Answer
  • Cellulose
  • Glycogen
  • Starch
  • Fructose

Question 4

Question
Long chains of single sugars covalently linked describes what types of carbohydrates?
Answer
  • Oligosaccharides
  • Multisaccharides
  • Polysaccharides
  • Megasaccharides

Question 5

Question
Which pair of molecules are epimers?
Answer
  • D-Glucose and D-Galactose
  • D-Glucose and L-Glucose
  • Threose and Erythrose
  • D-Glucose and D-Gulose

Question 6

Question
Which of these structures is glucose?

Question 7

Question
Galactose is a ___ epimer of glucose.
Answer
  • C1
  • C2
  • C3
  • C4

Question 8

Question
Which one of these is a ketohexose
Answer
  • Fructose
  • Glucose
  • Ribose
  • 2-Deoxy-Ribose

Question 9

Question
Which of these is not true?
Answer
  • Enantiomers are stereoisomers that are not mirror images
  • In sugars that contain the most chiral centers only the one that is the most distant from the caronyl carbon is designated as D or L
  • hemiacetals are formed by alcohols attacking aldehydes
  • Alcohol oxygen atom is nucleophilic

Question 10

Question
During the cyclisation of Monosaccharides which is/are true?
Answer
  • The carbon atom furthest from the former carbonyl atom becomes the anomeric carbon
  • The position of anomeric carbon's oxygen determines whether the anomer is α or β
  • The position of the anomeric carbon's hydroxyl group determines whether the anomer is α or β
  • The carbon atom furthest from the former carbonyl atom becomes the chiral center

Question 11

Question
Which of these are carbohydrates that have a chemical structure that includes a six-membered ring consisting of five carbon atoms and one oxygen atom?
Answer
  • Furanoses
  • Pyranoses

Question 12

Question
The disaccharide formed upon condesation of two glucose molecules via the 1-4 bond is called
Answer
  • Trehalose
  • Sucrose
  • Maltose
  • Lactose

Question 13

Question
Which of these describes cellobiose
Answer
  • α-D-glucopyranosyl-(1→2)-β-D-fructofuranoside
  • β-D-glucopyranosyl-(1→4)-β-D-glucopyranose
  • β-D-galactopyranosyl-(1→4)-α-D-glucopyranose
  • α-D-glucopyranosyl-(1→4)-β-D-glucopyranose

Question 14

Question
Polysaccharides...
Answer
  • can be branched but cannot have multiple monomer types
  • cannot be unbrached
  • have defined molecular weights
  • with only two monomer types cannot be branched

Question 15

Question
Which one of these hetero-polysaccharides has the largest size
Answer
  • peptidoglycan
  • agarose
  • hyaluronan

Question 16

Question
which of these is used in Algae cell walls
Answer
  • Peptidoglycan
  • hyaluronan
  • agarose

Question 17

Question
Glucose is stored in animals as
Answer
  • Glucagon
  • Glycogen
  • Glucose
  • Insulin
  • Starch

Question 18

Question
Glycogen is a polysaccharide in which glucose is joined by β-(1→4) linkages
Answer
  • True
  • False

Question 19

Question
Glycogen is a polysaccharide in which glucose is joined by α-(1→6) linkages
Answer
  • True
  • False

Question 20

Question
Which of the following is true
Answer
  • Amylose is the branched form of starch
  • α-amylase is a pancreatic enzyme that hydrolyses the α (1→4) linkages of starch
  • Glycogen has less α (1→4) linkages than starch
  • Glycogen has less α (1→6) linkages than starch

Question 21

Question
hydrolysis of cotton occurs
Answer
  • at the β (1→2) linkages of D-glucose
  • at the α (1→2) linkages of D-glucose
  • at the β (1→4) linkages of D-glucose
  • at the α (1→4) linkages of D-glucose

Question 22

Question
Which of the following is not true
Answer
  • Glycosidic bonds can freely rotate
  • more than 10^9 metric tonnes of cotton are produced/year
  • Starch can be coiled into a helical structure
  • Glycogen and amylopectin have only one reducing end

Question 23

Question
Which of these lack enzymes that can hydrolyse D-glucose β (1→4) linkages
Answer
  • Fungi
  • bacteria
  • termites
  • protozoa

Question 24

Question
Chitin
Answer
  • is a heteropolymer
  • consists of β (1→2) linkages of N-acetyl-D-glucosamine
  • is insoluble
  • once acetlated forms Chitosan

Question 25

Question
Sephadex gels separate proteins by
Answer
  • size
  • charge
  • polarity
  • shape

Question 26

Question
Which of these would you find in the first fractions after size exclusion chromatography
Answer
  • acidic proteins
  • the smallest proteins
  • the largest proteins
  • basic proteins

Question 27

Question
which of these are homoglycans
Answer
  • Agar
  • Dextrans
  • Peptidoglycan
  • None

Question 28

Question
Which of these can be linked to epichlorohydrin in sephadex beaded gels
Answer
  • Agar
  • Agarose
  • Peptidoglycan
  • Dextran

Question 29

Question
Agar is a complex mixture of heteropolysaccharides containing modified
Answer
  • Glucose units
  • Mannose units
  • Fructose units
  • None of the above

Question 30

Question
Which of these is false
Answer
  • Agarose can be used for growing bacteria
  • Agarose is a component of bacterial cell walls
  • Agarose can be used for DNA separation
  • Agar is a component of seaweed cell walls

Question 31

Question
N-acetyl-galactosamine is a ___ epimer of N-acetyl-glucosamine
Answer
  • C3
  • C2
  • C4
  • C6

Question 32

Question
Where wold yo expect to find hyaluronate
Answer
  • ECM of Cartilage
  • Hair
  • Nails
  • Horns

Question 33

Question
Which one of these glycosaminoglycans acts as a lubricant?
Answer
  • Chondrotin-4-sulfate
  • keratan sulfate
  • heparin
  • hyaluronate

Question 34

Question
which one of the has approximately 50'000 disaccharides per chain
Answer
  • hyaluronate
  • keratan sulfate
  • heparin
  • chondrotin-4-sulfate

Question 35

Question
Which one of these glycosaminoglycans consists of [galactose β(1,4) Glc-NAc6S] repeating disaccharides
Answer
  • hyaluronate
  • chondrotin-4-sulfate
  • heparin
  • keratan sulfate

Question 36

Question
Which of these repeating disaccharides make dermantan sulfate?
Answer
  • glucaronic acid and N-acetylglucosamine
  • glucaronic acid and N-acetylgalctosamine-4-sulfate
  • Iduronic acid and N-acetylgalactosamine-4-sulfate
  • Iduronic acid and N-acetylglucosamine

Question 37

Question
The cabohydrate attached to a protein in a Glycoconjugate attaches via...
Answer
  • The C6 carbon
  • The anomeric carbon
  • The furthest carbon from the anomeric carbon
  • The C2 carbon

Question 38

Question
Which of the following most likely contains the most glycosylated proteins (Glycoproteins)
Answer
  • Humans
  • E.coli
  • Ebola virus
  • Cats

Question 39

Question
O linked oligosaccharides are linked through the N terminus of the amino acid
Answer
  • True
  • False

Question 40

Question
In glycoproteins, sugars are attached either to the amide nitrogen atom in the side chain of asparagine (termed an N-linkage) or to the oxygen atom in the side chain of serine or threonine (termed an O-linkage)
Answer
  • True
  • False

Question 41

Question
Glycophorin A is the most important attachment site for which of the following parasites in order to enter erythrocytes
Answer
  • Plasmodium falciparum
  • Chilomastix mesnili
  • Entamoeba coli
  • Entamoeba dispar

Question 42

Question
Which of these sulfated glycosaminoglycans are attached to a protein anchored to a membrane lipid?
Answer
  • syndecans
  • glypicans

Question 43

Question
NB! Select all which are functions of polysaccharides
Answer
  • Labelling of proteins for destruction
  • Recognition sites for growth factors
  • recognition sites for bacteria
  • localization of certain proteins

Question 44

Question
Which one of these is not a main component of the extracellular matrix (ECM)
Answer
  • Proteoglycan aggregates
  • Collagen fibers
  • Elastin
  • Fatty acids

Question 45

Question
Which one of these in not a characteristic of Glycosaminoglycans
Answer
  • Negatively charged
  • C5 oxidation
  • one monomer is either N-acetyl-glucosamine or N-acetyl-galactosmine
  • found in connective tissue

Question 46

Question
Plasmodium flaciparum requires which of these as an attachment site to enter erythrocytes
Answer
  • Glycophorin A
  • Hyaluronan
  • syndecan
  • Podocalyxin

Question 47

Question
Which of these about proteoglycans is not true
Answer
  • Proteoglycan aggregates are found in articula cartilage
  • Proteoglycans influence growth factor activation and adhesion
  • glycosaminoglycans are linked to the core protein from the anomeric carbon
  • proteoglycanaggregates form high friction material

Question 48

Question
Which of these are integral receptors for extracellular proteoglycans
Answer
  • Integrins
  • actin
  • collagen fibers
  • elastin

Question 49

Question
Which of these about enzymatic reactions is true
Answer
  • Enzymes directly affect equilibrium (∆G)
  • Entropy cost is paid during binding
  • enzymes increse reaction rates (κ ) by increasing (∆G)
  • slow reactions do not have high activtaion barriers

Question 50

Question
Rate of enzymatic reactions are affected by....? (Click all true)
Answer
  • concentration of enzyme
  • concentration of substrate
  • temperature
  • shape of enzyme
  • shape of substrate

Question 51

Question
Which one of these describes a micelle
Answer
  • individual units are wedge shaped
  • artificial carriers of molecules
  • individual units are cylindrical
  • composed lipid-based structures that form pliable sheets

Question 52

Question
Which of these is false
Answer
  • membranes vary from 3-10nm
  • membranes form spontaneously by noncovalent forces
  • membranes are symmetric
  • membranes can be found within cells

Question 53

Question
Which of these is true about fatty acids
Answer
  • Most natural fatty acids are branched
  • Saturated fatty acids have double bonds between carbons in the chain
  • Most natural fatty acids have an even number of C's
  • linoleic acid is a saturated fatty acid

Question 54

Question
Which of these is false about fatty acids
Answer
  • Fatty acids solubility decreases as the chain length increases
  • Melting point decrases as the chain length decreses
  • Melting point increases as the number of double bonds increases
  • unsaturated cis fatty acids have a lower melting point than saturated fatty acids

Question 55

Question
Omega-3 (ω-3) fatty acids have
Answer
  • a double bond between the 2nd and 3th carbon from the methyl end of the chain.
  • a double bond between the 3rd and 4th carbon from the methyl end of the chain.
  • a double bond between the 1st and 2nd carbon from the methyl end of the chain.
  • a double bond between the 2nd and 3nd as well as 3rd and 4th carbon from the methyl end of the chain.

Question 56

Question
Which of these is untrue
Answer
  • Triacylglycerols are polar
  • Triacylglycerols are non hydrated
  • Vegetable oils are composed of triacylglycerols with unsaturated fatty acids
  • Animal fats are composed of triacylglycerols with saturated fatty acids

Question 57

Question
which of these is a greasy solid at room tempreature
Answer
  • triacylglycerols with unsaturated fatty acids
  • triacylglycerols with saturated fatty acids

Question 58

Question
which of these is a sphingolipid

Question 59

Question
Which of these is the head group of phosphatidylserine

Question 60

Question
Which of these has a net charge of -4 at pH7
Answer
  • phosphatidylcholine
  • cardilipin
  • phosphatidylglycerol
  • phosphatidylinositol 4,5- biphosphate

Question 61

Question
Which of these is the major component of most eukaryotic cell membranes
Answer
  • phophatidylcholine
  • phosphatidylglycerol
  • cardiolipin
  • phosphatidylethanolamine

Question 62

Question
a fatty acid is joined to sphingosine via an
Answer
  • ester linkage
  • amide linkage
  • glycosidic linkage
  • phosphodiester linkage

Question 63

Question
ganglioside GM2 has which of these as a head group
Answer
  • glucose
  • galactose
  • di, tri, or tetrasaccharide
  • complex oligosaccharide

Question 64

Question
The blood groups are determined in part by the
Answer
  • type of sugars located on the head groups in glycosphingolipids
  • type of sugars located on the head groups in glycolipids
  • type of sphingolipids
  • type of galactolipids

Question 65

Question
The structure of sugars located on the head groups in glycosphingolipids is determined by an expression of specific glycosyltransferases. Individuals with a glycosyltransferase that transfers an N-acetylgalactosamine group will
Answer
  • will have the O antigen
  • A blood group
  • B blood group
  • AB blood group

Question 66

Question
which of thes is false
Answer
  • Cholesterol modulates cell membrane fluidity
  • Mammals can not synthesize cholesterol
  • cholesterol in loe density lipoproteins tend to deposit in arteries
  • most bacteria lack sterols

Question 67

Question
which of these polyketides is an antibiotic
Answer
  • erythromycin
  • amphotericin B
  • lovastatin

Question 68

Question
which of these lipids are hormone precursors
Answer
  • vitamins E and K
  • vitamins A and D
  • steroid hormones
  • eicosanoids

Question 69

Question
which of these lipids are paracrine hormones
Answer
  • phosphatidylinositols
  • vitamins A and D
  • vitamins E and K
  • Dienes
  • eicosanoids

Question 70

Question
which of these is true
Answer
  • cholesterol is predominant in mitochondrial membranes
  • galactolipids are abundant in animals
  • membranes have non-selective import and export across the membrane
  • archaebacteria have monolayer instead of a bilayer

Question 71

Question
which of these is a type 6 integral membrane protein

Question 72

Question
Which of these amino acid residues would you find predominantly in the transmembrane segments of membrane proteins
Answer
  • Tyr
  • Thr
  • Ser
  • Pro

Question 73

Question
Proteins can be targeted to the INNER leaflet of the plasma membrane by farnesylation. The primary sequence of the protein contains a signature for farnesylation which is
Answer
  • CaaX
  • MaaX
  • CaX
  • MaX

Question 74

Question
hutchinson-gilford progeria syndrome is caused by
Answer
  • palmitoylation defect
  • myristoylation defect
  • farnesylation defect

Question 75

Question
which of these are only found on the outside of cell membranes
Answer
  • proteins
  • lipids
  • carbohydrates

Question 76

Question
which of these statements about the physical properties of membranes is true
Answer
  • Permeable to large polar solutes and ions
  • Not permeable to small polar solutes and nonpolar compounds
  • Permeability can be artificially increased by chemical treatment
  • Exist in a single phase and cannot undergo phase transitions

Question 77

Question
Heating causes
Answer
  • cell membrane transition from the gel to fluid
  • cell membrane transition from the fluid to gel
  • cell membrane changed to become not permeable to large polar solutes
  • cell membrane changed to become permeable to small polar solutes and nonpolar compounds

Question 78

Question
Which of these statements on membrane fluidity is incorrect
Answer
  • is determined mainly by the fatty acid composition
  • more fluid membranes require shorter and more unsaturated fatty acids
  • At higher temperatures cells need more saturated fatty acids to maintain fluidity
  • Gel phase means that the individual molecules do not move around

Question 79

Question
which of these increase in membrane compisition percentage when temperatures increase
Answer
  • Myristic acid
  • palmitoleic acid
  • oleic acid
  • hydroxymyristic acid

Question 80

Question
Cell membranes of .... contain hopanols instead of sterols
Answer
  • animals
  • bacteria
  • plants
  • fungi

Question 81

Question
Membrane Dynamics: Transverse Diffusion. Spontaneous flips of individual lipids from one leaflet to another are rare because...
Answer
  • the hydrophobic head group must transverse the hydrophilic tail region of the membrane
  • membrans are rigid and individual lipids cannot move at all
  • the charged head group must transverse the hydrophobic tail region of the membrane

Question 82

Question
Which is false about flippases
Answer
  • catalyze transverse diffusion
  • catalyze lateral diffusion
  • use ATP
  • move lipids against the concentratiion gradient

Question 83

Question
Tick ALL that are true!!
Answer
  • Membrane Lipid Rafts contain clusters of glycosphingolipids with longer-than-usual tails
  • Membrane Lipid Rafts are more ordered than the rest of the membrane
  • Membrane fusion can only occur through protein mediation
  • Passive diffuision of polar molecules across cell membranes has a high activation barrier

Question 84

Question
Which of these is a membrane receptor that detects light
Answer
  • opsin
  • insulin receptor
  • acetylcholine receptor
  • maltoporin

Question 85

Question
Which of these is a membrane receptor that detects neurotransmitters
Answer
  • opsin
  • acetylcholine receptor
  • maltoporin
  • insulin receptor

Question 86

Question
Cystic fibrosis (Mucoviscidose) is caused by
Answer
  • a mutation to a Cl- ion channel in epithelial cells
  • a mutation to a K+ ion channel in epithelial cells
  • a mutation to a Na+ ion channel in epithelial cells
  • a mutation to a Ca2+ ion channel in epithelial cells

Question 87

Question
Tick ALL that are correct
Answer
  • Energy of ATP hydrolysis can be used to drive protons through the membrane
  • Energy of the proton gradient can be used to synthesize ATP
  • Primary active transport is a form of active transport across a biological membrane in which a transporter protein couples the movement of an ion (typically Na+ or H+) down its electrochemical gradient to the uphill movement of another molecule or ion against a concentration/electrochemical gradient.
  • glucose is cotransported with Na+ in intestinal epithelial cells

Question 88

Question
Which of these plasma proteins is the most abundant
Answer
  • transferrin
  • ceruloplasmin
  • immunoglobulins
  • albumin

Question 89

Question
What is labelled as B?
Answer
  • blood
  • plasma
  • White blood cells
  • ficoli

Question 90

Question
What is labelled as D
Answer
  • Plasma
  • White blood cells
  • Ficoli
  • white blood cells

Question 91

Question
Which of these are not a hematopoietic cells
Answer
  • eosinophils
  • basophils
  • neutrophils
  • thrombocytes

Question 92

Question
Which of these is derived from lymphoid stem cells
Answer
  • erythrocytes
  • T cells
  • basophil
  • neutrophil

Question 93

Question
Which one of these leukocytes secretes histamine and mediates inflammation
Answer
  • neutrophils
  • basophils
  • eosinophils
  • macrophages

Question 94

Question
Which of these leukocytes produces Ab (antibodies)
Answer
  • Neutrophils
  • T cells
  • B cells
  • Macrophages

Question 95

Question
Where is myoglobin found
Answer
  • in the bone marrow
  • freely circulating in the blood
  • in skeletal and striated muscles
  • restricted to erythrocytes

Question 96

Question
which of these is false
Answer
  • myogloblin stores oxygen in the cytoplasm and delivers it to mitochondrion
  • hemoglobin is restricted to erythrocytes
  • Heme (B) is the oxygen binding molecule found only in hemoglobin
  • the distal histidine of the myglobin protein hydrogen bonds with oxygen bound to the protein

Question 97

Question
Consider a process in which a ligand (L) bind reversibly to a site in a protein (P). After some time, the process will reach equilibrium where the Ka (association rate constant) and Kd (dissociation rate constant) rates are equal. which of these equations represents the equilibrium.
Answer
  • kd [P].[L] = ka [PL]
  • ka [P].[L] = kd [PL]
  • [P].[L] = [PL]
  • ka [P].[L] > kd [PL]

Question 98

Question
Which of these statements is false
Answer
  • when the first binding event increases affinity at the remaining sites it is called positive cooperativity
  • when the first binding event decreases affinity at the remaining sites it is called negative cooperativity
  • oxygen binds to heme better than carbon monoxide
  • nH( hill coefficient) > 1 equals positive cooperativity

Question 99

Question
Cooperativity can be described as
Answer
  • positive homotropic regulation
  • negative homotropic regulation
  • positive heterotropic regulation
  • negative heterotropic regulation

Question 100

Question
Which of these statement on hemoglobin is false
Answer
  • oxygen binding triggers a tense to relaxed state conformational change
  • tense state has a higher affinity for oxgen than the relaxed state
  • conformational change from the T state to the R state invloves breaking ion pairs between the alpha1-beta2 interface of hemoglobin
  • 2,3 -Bisphosphoglycerate is a negative heterotropic regulator of hemoglobin function

Question 101

Question
which of these is a non-phosphorylated nitrogenous base
Answer
  • nucleoside
  • nucleotide
  • nucleobase
  • nucleomide

Question 102

Question
Which side are the purines
Answer
  • A
  • B

Question 103

Question
Which color is encircling where a glycosidic bond between the nitrogenous base and the sugar would be present
Answer
  • red
  • green
  • blue
  • none of the above

Question 104

Question
Which letter represents deoxyadenylate
Answer
  • A
  • B
  • C
  • D

Question 105

Question
Which letter represents deoxythymidylate
Answer
  • A
  • B
  • C
  • D

Question 106

Question
Which letter represents deoxyguanylate
Answer
  • A
  • B
  • C
  • D

Question 107

Question
Which letter is representing cytidylate (CMP)
Answer
  • A
  • B

Question 108

Question
Which of these statements about the purine and pyrimidine bases is true
Answer
  • Cytosine is found in both DNA and RNA
  • Neutral molecules at pH 7
  • Guanine pKa at N7 is 2.4
  • all the above

Question 109

Question
In nucleotides the pentose ring is attached to the nucleobase via a
Answer
  • β -N-Glycosidic Bond
  • α -N-Glycosidic Bond
  • Hydrogen bond
  • none of the above

Question 110

Question
In DNA structure there is free rotation about
Answer
  • C-1’-N-glycosyl bond
  • C-2’-N-glycosyl bond
  • C-3’-N-glycosyl bond
  • C-4’-N-glycosyl bond

Question 111

Question
How many base pairs do you find in the A form of DNA
Answer
  • 10.5
  • 11
  • 12
  • 13

Question 112

Question
The aromaticity of the nucleotide bases and their dipole moments is important for which interactions in DNA
Answer
  • Van der Waal forces in base stacking
  • link between base and sugar in a nucleotide
  • the link between two different nucleotides
  • interstrand bonding and complementarity

Question 113

Question
Figure A represents which type of DNA secondary structure
Answer
  • hairpin
  • mirror image
  • palindrome
  • cruciform

Question 114

Question
Figure C represents which type of DNA secondary structure
Answer
  • Cruciform
  • Palindrome
  • Hairpin
  • Mirror image

Question 115

Question
DNA sequences with a very high proportion of G residues forms which unusual DNA structure found on chromosome telomeres
Answer
  • tetraplex DNA
  • triplex DNA
  • inverted repeats
  • cruciforms

Question 116

Question
Which of these are a quaternary DNA structure
Answer
  • Chromatin
  • hairpin
  • supercoil
  • Triplex

Question 117

Question
In mammals ____ Functions as an autocoid, or "local hormone"
Answer
  • Adenosine
  • Guanine
  • Cytosine
  • Thymine

Question 118

Question
Which one of these is an RNase enzyme that prevents inbreeding of plants
Answer
  • S-RNase
  • RNase-P
  • Dicer
  • None of the above

Question 119

Question
_____ is an enzyme that cleaves double-stranded RNA into oligonucleotides
Answer
  • S-RNase
  • Dicer
  • RNase P

Question 120

Question
Why would animal cells need an enzyme that cleaves double-stranded RNA into oligonucleotides
Answer
  • processessing tRNA precursors
  • protection from viral genomes
  • using RNA as an energy source
  • using RNA in Coenzymes

Question 121

Question
RNA would be unstable in which of the conditions listed below
Answer
  • pH 1
  • pH 3
  • pH 6
  • pH 10
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