Question 1
Question
Glia cells have to categories: Microglia and Macroglia
One type pf microglia are [blank_start]Macrophages[blank_end] that are responsible for cleaning up dead tisse
The three types of [blank_start]Macroglia[blank_end] are Asctocytes, Oligodendrocytes, and Schwann Cells
Answer
-
Macrophages
-
Astrocytes
-
Oligodendrocytes
-
Schwann Cells
-
Macroglia
-
Macrophages
-
Microglia
-
Masterglia
Question 2
Question
What type of Glial cell provides physical support, chemical support, and creates the blood brain barrier?
Answer
-
Astrocytes
-
Oligodendrocytes
-
Schwann Cells
Question 3
Question
What type of glial cell creates a myelin sheath, assists in conduction, and is confined to the CNS?
Answer
-
Astrocytes
-
Schwann Cells
-
Oligodendrocytes
Question 4
Question
What type of glial cell are single cells that wrap around axons, create the myelin sheath, assist in conduction, and are confined to the PNS?
Answer
-
Oligodendrocytes
-
Astrocytes
-
Schwann Cells
Question 5
Question
Typically there is more...
Question 6
Question
What equation describes the relation between concentration differences of a permeating ion (free flow) across a membrane and the membrane potential at equilibrium?
Answer
-
The Goldman Equation
-
V=IR
-
The Nernst Equation
-
v=m/s
Question 7
Question
In the Nernst equation the shortcut numbers from valence 1 (Na+, K+) and 18 degrees to 37 degrees and from valence 2 (Ca2+) and 18 to 37 degrees are...
Answer
-
58,29,30.5,61
-
58,61,29,30.5
-
57,61,28,30.5
-
29,30.5,58,61
Question 8
Question
When using the Nernst equation for ions with a negative valence (Cl-) you must switch the concentration protion of the equation to Cin/Cout rather than Cout/Cin
Question 9
Question
With ion free flow..
K+ should produce a [blank_start]-[blank_end]'ve environment inside the cell
Na+ should produce a [blank_start]+[blank_end]'ve environment inside the cell
Cl- should produce a [blank_start]-[blank_end]'ve environment inside the cell
Question 10
Question
What equation takes into account permeability and assumes infinite permeability with regard to ion movement?
Answer
-
The Nernst Equation
-
The Goldman Equation
-
The Ion Equation
-
None of the above
Question 11
Question
The resting voltage potential of...
K+ is [blank_start]-75[blank_end]mV
Na+ is [blank_start]+54[blank_end]mV
Cl- is [blank_start]-56[blank_end]mV
Question 12
Question
When a membrane moved from -65mV -> a more negative value it is known as
Answer
-
Depolarization
-
Hyperpolarization
-
Neutral polarization
-
Additive polarization
Question 13
Question
The time constant (t) represents how quickly membrane potential changes with charge and...
Answer
-
Represents the duration of time a membrane takes to reach 53% of its max V
-
Represents the duration of time a membrane takes to reach 67% of its max V
-
Represents the duration of time a membrane takes to reach 63% of its max V
Question 14
Question
The statement below correstond to:
- anything physical preventing movement of charge down an axon
- the ability of charge to leak from the axon
Answer
-
Ri and Rm
-
Rm and Ri
-
Rf and Ri
-
Rt and Rm
Question 15
Question
The length constant lambda measures how far along an axon you have to travel before there is a significant change in membrane potential (27% of initial V)
Question 16
Question
What are the passive electrical properties?
Question 17
Question
An excitatory response usually refers to the movement of [blank_start]Na+[blank_end] ions, and an inhibitory response is often refering to the movement of [blank_start]Cl-[blank_end] ions.
Question 18
Question
What are the characteristics of an Axon Hillock?
Answer
-
Its the origin of the action potential
-
It is known as the integration center
-
It is dense in voltage gates Na+ Channels
-
It is dense in GAP Junctions
-
It is the origin of the axon form the cell body
Question 19
Question
Ion Channels have...
Answer
-
4 domains
-
6 domains
-
4 membrane spanning segments
-
6 membrane spanning segments
-
an "l-loop" to create a pore for ions to travel through
-
a "p-loop" to create a pore for ions to travel through
Question 20
Question
[blank_start]A Ligand Gated Channel[blank_end]: depends on ligand presence
[blank_start]Phosphorylation Gated Channel[blank_end]: if an intracellular component is phosphorylated the channel will open
[blank_start]Stretch or Pressure Gated Channel[blank_end]: Cytoskeletal proteins adhere channel to membrane, any disruption of membrane causes cytoskeleton proteins to tighten-> channel opens
Question 21
Question
K+ Voltage gated channels...
Question 22
Question
What is the most important mode of ion channel selectivity?
Answer
-
Chemoreception
-
Hydration Shells
-
Physical size
-
Shape
Question 23
Question
What are the characteristics of an Action Potential?
Question 24
Question
The action potential:
[blank_start]Resting Phase[blank_end]: key components of AP are K+ channels and voltage gated Na+ and K+ channels
[blank_start]Depolarization[blank_end]: Charge already in axon moves from a different site, build up of positive charge
[blank_start]Rising phase[blank_end]: activation threshold passed, Na+ channels open, rapid depolarization
[blank_start]Overshoot[blank_end]: AP approaches Nernst potential for Na+
[blank_start]Falling Phase[blank_end]: Na+ channels become inactive, some K+ channels open
[blank_start]Undershoot[blank_end]: occurs because K+ channels cant close quickly, permeability to K+ greater than at rest
[blank_start]Repolarization[blank_end]: more K+ channels close, Na+/K+ pump returns the membrane to resting potential
Answer
-
Resting Phase
-
Depolarization
-
Rising phase
-
Overshoot
-
Falling Phase
-
Undershoot
-
Repolarization
Question 25
Question
The unidirectionality of the Action Potential is due to the fact that Na+ channels inactivate
Question 26
Question
What are the periods of time after an AP where it is impossible and difficult to generate another AP?
Answer
-
Relative and Absolute Refractory Period
-
Negative and Positive Refractory Period
-
Up and Down Refractory Period
-
Absolute and Relative Refractory Period
Question 27
Question
What makes it hard to trigger a second AP in close proximity to an initial AP?
Answer
-
Increased K+ permeability
-
The temperature of the membrane
-
The inactivation of Na+ channels
-
The unidirectionality
-
The decreased membrane resistance
Question 28
Question
What factors influence the conduction velocity of an axon?
Answer
-
Length
-
Diameter
-
Temperature
-
Shape
-
Myelination
-
None of the above
Question 29
Question
Increased diameter increases internal resistance
Question 30
Question
Decreased Ri leads to an increased lamda (length constant)
Question 31
Question
Myelination effects Ri
Question 32
Question
A 2 degree temperature change increases conduction my 2x
Question 33
Question
increased diameter= decreased Ri= increased S.A= increased Rm
Question 34
Question
What characterizes Gap Junctions?
Answer
-
Chemical synapses
-
Electrical synapses
-
Non-chemical communication
-
Slow response
-
Two hemi channels
-
Blocking connection between two cells
-
Ions and proteins can pass through
-
Rapid communication
-
Synchrony between cells
-
Bidirectional movement
Question 35
Question
You usually find Gap Junctions in cardiomycetes, in the retina, various aquatic animals (escape response, electrical), in glial cells, and in neurons
Question 36
Question
What is the entire purpose of an Action Potential?
Question 37
Question
What is the most common excitatory neurotransmitter?
Answer
-
GABA
-
Glutamate
-
Glucose
-
Dopamine
Question 38
Question
What is the most common inhibitory neurotransmitter?
Answer
-
GABA
-
Glutamate
-
Inhibin
-
Serotonin
Question 39
Question
An Axon Collateral is when an axon splits into a bunch of different arms (with the same AP) and activates a larger area of muscle tissue
Question 40
Question
The Nicotinic ACh Receptor has
Answer
-
4 domains
-
5 domains
-
4 membrane spanning segments
-
5 membrane spanning segments
-
Needs 1 site bound with ACh for activation
-
Once open allows Na+ and K+ to pass through
-
Once open has a net hyper-polarizing effect
Question 41
Question
[blank_start]7[blank_end]. Degradation of the neurotransmitter by acetylcholinesterase
[blank_start]2[blank_end]. Voltage gated Ca2+ channels activate
[blank_start]4[blank_end]. ACh binding to ACh receptors
[blank_start]3[blank_end]. Exocytosis
[blank_start]8[blank_end]. Reuptake of broken down neurotransmitter
[blank_start]6[blank_end]. Na+ channel activation
[blank_start]5[blank_end]. Depolarization of the post synaptic cell
[blank_start]1[blank_end]. Depolarization, charge arrives at the terminal
Question 42
Question
What are the correct steps within neurotransmitter release?
[blank_start]4[blank_end]. Priming
[blank_start]1[blank_end]. Reserve Pool
[blank_start]6[blank_end]. Endocytosis
[blank_start]2[blank_end]. Targeting
[blank_start]5[blank_end]. Exocytosis
[blank_start]3[blank_end]. Docking
Question 43
Question
What are two types of v-snares?
Answer
-
Synaptolagmin
-
Snap25
-
Syntaxin
-
Synaptobrevin
Question 44
Question
What are two t-snares with regard to vesicle binding?
Answer
-
Synaptolagmin
-
Syntaxin
-
Snap25
-
Syntaptobrevin
Question 45
Question
In vesicle binding...
[blank_start]Targeting[blank_end]= vesicle moves close to membrane
[blank_start]Docking[blank_end]= snare complex
[blank_start]Priming[blank_end]= Ca2+ interacts with synaptolagmin
[blank_start]Fusion[blank_end]= opens up vesicle
Answer
-
Targeting
-
Docking
-
Priming
-
Fusion
Question 46
Question
[blank_start]Neuroendocrine[blank_end]= released by nerve cells into circulation-> target cell
[blank_start]Paracrine[blank_end]= released and diffuses to the target tissue through the extracellular fluid
[blank_start]Autocrine[blank_end]= target cell is the same cell releasing the hormone (must bind a receptor on membrane to activate pathway)
[blank_start]Neurocrine[blank_end]= neuron secretes in the immediate vicinity of target cell
[blank_start]Pheromone[blank_end]= released into the environment-> biological response
Answer
-
Neuroendocrine
-
Paracrine
-
Autocrine
-
Neurocrine
-
Pheromone
Question 47
Question
What type of hormone is the most common in the body, and has an a.a backbone?
Question 48
Question
What hormone has a cholesterol backbone and includes androgens, estrogen, progesterone, and corticosteroids?
Question 49
Question
What hormone is produced by membranes?
Question 50
Question
With signal transduction from receptors what is the term for a hormone stimulating biological activity, blocking biological activity and for binding without stimulating biological activity?
Answer
-
Competitive antagonists, antagonists and agonists
-
Antagonists, agonists, and competitive antagonists
-
agonists, antagonists, and competitive antagonists
-
agonists, competitive antagonists, and antagonists
Question 51
Question
K+1/K-1= Ka
This equation represents what of a hormone/receptor interaction?
Answer
-
Affinity- how tightly the hormone was bound
-
Equilibrium Dissociation Constant
-
Equilibrium Association Constant
-
How such hormone is required for high affinity
-
units= M-1sec-1
-
units= sec-1
Question 52
Question
1/Ka=Kd
This equation represents what of a hormone/receptor interaction?
Answer
-
Equilibrium Dissociation Constant
-
Equilibrium Association Constant
-
Affinity- how tightly a hormone will bind
-
How much of a hormone is required for high affinity
-
units= sec-1
-
units= M-1sec-1
Question 53
Question
A hormone that is more specific to the receptor requires a [blank_start]smaller[blank_end] concentration to reach Kd
Question 54
Answer
-
effective dose of a hormone giving half of the maximal response
-
a measure of potency
-
is a function of receptor affinity
-
is a set value for all receptors
-
a measure for receptor saturation
Question 55
Question
upregulation refers to the increased production of receptors and downregulation refers to the decreased production of receptors
Question 56
Question
Receptor capacity change effects [blank_start]max response[blank_end]
Receptor affinity effects [blank_start]ED50[blank_end]
Question 57
Question
What characteristics relate to intracellular receptors?
Answer
-
They are in the cytoplasm or nucleus
-
They are in the membrane
-
Steroids and iodothyronines
-
receptor transitions into a transcription factor after its bound
-
Ultimately leads to the synthesis of new proteins
-
Ultimately leads to the synthesis of lipids
-
Associated with accesory proteins
Question 58
Question
What are the two types of membrane receptors?
Question 59
Question
Which statement about Receptor Tyrosine Kinases is TRUE?
Answer
-
The alpha subunit is the extracellular and transmembrane segment
-
The beta subunit contains hormone binding side
-
Dimerization occurs after hormone binding
-
Leads to the dephosphorylation of proteins
Question 60
Question
Which of the following statements is TRUE regarding ion channel receptors?
Answer
-
The channel is a receptor but not an effector
-
The channel doesn't require hormone binding for activation
-
A conformational change occurs once the ligand binds
-
The channel is known as an intracellular receptor
Question 61
Question
Which of the following are types of G-proteins?
Question 62
Question
Within a G-protein coupled receptor and the alpha, beta, and gamma subunits, the subunit [blank_start]alpha[blank_end] acts as the effector enzyme
Question 63
Question
G-protein receptors Gs an Gi function to stimulate and inhibit...
Question 64
Question
Within the G-protein coupling pathway regarding adenylyl cyclase, what are the steps to biological response?
[blank_start]3[blank_end]. Phosphorylation of Adenylyl Cyclase
[blank_start]1[blank_end]. Substrate binds receptor
[blank_start]4[blank_end]. Activation of cAMP
[blank_start]6[blank_end]. Biological response
[blank_start]2[blank_end]. Dissociation of G-protein subunits
[blank_start]5[blank_end]. Phosphorylation of serine and threonine residues on target proteins
Question 65
Question
What enzyme reverses the action of cAMP?
Answer
-
Glucanase
-
Cholesterase
-
Phosphodiesterase
-
Lipase
Question 66
Question
What characterizes Phosphodiesterase?
Answer
-
inactivates cAMP by hydrolyzing the ring to 3' AMP
-
inactivates cAMP by hydrolyzing the ring to 5' AMP
-
inhibited by a family of methylxanthines (ex. caffeine)
-
inhibited by neurotransmitters
-
Has only 2 different forms
Question 67
Question
What characterizes Gq/11 G-proteins?
Answer
-
Most known as Cl- mobilizing hormones
-
Most known as Ca2+ mobilizing hormones
-
Activates Phospholipase-C (PLC)
-
Activates Phosphodiesterases
-
Activates phosphatidyl inositol turnover
-
PLC converts phosphatidyl inositol to IP3 and DAG
(inositol triphosphate and diacylglycerol)
Question 68
Question
The pathway sequence with regard to Gq G-proteins goes...
[blank_start]1[blank_end]. Binding of ligand to receptor
[blank_start]6[blank_end]. Increase in intracellular Ca2+
[blank_start]3[blank_end]. Dissociation of Galphaq subunit
[blank_start]7[blank_end]. Activation of Protein Kinase C (PKC)
[blank_start]4[blank_end]. Activation of phosphatidyl inositol and phospholipase C
[blank_start]9[blank_end]. Biological response
[blank_start]5[blank_end]. PLC converts PI into two messangers (IP3 and DAG)
[blank_start]2[blank_end]. Phosphorylation of Galphaq subunit
[blank_start]8[blank_end]. Phosphorylation of a.a residues on target proteins
Question 69
Question
The anterior pituitary is derived from dorsal outgrowth of [blank_start]buccal cavity[blank_end] ([blank_start]roof of mouth[blank_end])
The posterior pituitary [blank_start]embryologically[blank_end] derived from the [blank_start]brain[blank_end]
Answer
-
buccal cavity
-
the brain
-
roof of mouth
-
the hypothalamus
-
embryologically
-
zygotically
-
physiologically
-
brain
-
roof of the mouth
Question 70
Question
Pituitary function is regulated by the production of neurohormones in the hypothalamus
Question 71
Question
The entire pituitary gland is also known as the....
Answer
-
Neurohypophysis
-
Adenohypophysis
-
Hypophysis
-
Nuclei cluster
Question 72
Question
What characterizes Neurohypophysis?
Answer
-
Pars Nervosa
-
Pars Distalis
-
Pars Intermedia
-
Oxytocin
-
Vasopressin (ADH)
-
Synthesis of hormones in the Pituitary
-
Synthesis of hormones in the Hypothalamus
-
Release into the blood stream
Question 73
Question
What characterizes Adenohypophysis?
Question 74
Question
The sections of the pituitary...
Anterior lobe= Pars [blank_start]Distalis[blank_end]
Intermediate lobe= [blank_start]Pars Intermedia[blank_end]
[blank_start]Neural[blank_end] lobe/Posterior lobe= [blank_start]Pars Nervosa[blank_end]
Answer
-
Distalis
-
Pars Intermedia
-
Pars Nervosa
-
Neural
Question 75
Question
Antidiuretic hormone (also known as AVP) acts through two types of receptors...
V1= mediate vascular [blank_start]smooth muscle contraction[blank_end] (ex. [blank_start]vasoconstriction[blank_end] leads to increase blood pressure)
V2= produces [blank_start]renal action[blank_end] of AVP (ex. [blank_start]conserves water[blank_end] to increase blood pressure)
Question 76
Question
AVP secretion effect on blood pressure:
[blank_start]Increased[blank_end] BP->[blank_start]activation[blank_end] of baroreceptors->[blank_start]increased[blank_end] AVP secretion->increased [blank_start]H2O[blank_end] uptake (V2 receptor) and [blank_start]constriction[blank_end] of arterioles (V1 receptor)->increase BP
Answer
-
Increased
-
Decreased
-
High
-
Low
-
activation
-
inhibition
-
lipid binding
-
increased
-
decreased
-
moderate
-
unnecessary
-
H2O
-
Salt
-
Sugar
-
Nutrient
-
Constriction
-
Dilation
-
Looping
Question 77
Question
AVP effect on plasma osmolality:
Increased blood osmolality->[blank_start]activate[blank_end] osmoreceptors in CNS->[blank_start]increased[blank_end] AVP secretion->increased H2O [blank_start]retention[blank_end] (V2) and increased Na+ secretion (V2)->increased urine [blank_start]concentration[blank_end] and decreased urine [blank_start]volume[blank_end]
Answer
-
activate
-
deactivate
-
inactivate
-
increased
-
decreased
-
maintained
-
retention
-
secretion
-
mediation
-
storage
-
concentration
-
fluidity
-
temperature
-
dilution
-
volume
-
flow
-
production rate
Question 78
Question
Oxytocin effects...
Answer
-
Milk release after parturition
-
Blocks milk release
-
Stimulates uterine contraction
-
Inhibits uterine contraction
-
Stimulates contraction of myometrium
-
Inhibits contraction of myometrium
-
undergoes positive feedback
-
undergoes negative feedback
-
Secretion induced from stretching of birth canal in birth
Question 79
Question
[blank_start]Negative[blank_end] feedback loops are responsible for maintaining homeostasis
Question 80
Question
What is Family 1 of peptide hormones involved in adenohypophysis?
Question 81
Question
What s Family 2 of peptide hormones of adenohypophysis?
Question 82
Question
What belongs to Family 3 of peptide hormones of adenohypophysis?
Question 83
Question
What is an example(s) of glycoprotein hormone(s)?
Question 84
Question
What are examples of Gonadotropin hormones?
Question 85
Question
Family II of Peptide Hormones have two separate units, the alpha units which are the [blank_start]same[blank_end] for all peptide hormones and beta subunits which are [blank_start]different[blank_end] and confer the [blank_start]special function[blank_end] of the hormone
Answer
-
same
-
regulated
-
variable
-
replacible
-
different
-
uniform
-
gelatenous
-
rare
-
special function
-
size
-
potency
-
necessity
Question 86
Question
Pro-opiomelanocortin (POMC) has one gene that produces one protein that is cleaved in the ER in order to produce many biologically active fragments. They are cleaved by a family of prohormone convertases
Question 87
Question
What factors effect the release of Prolactin (PRL)?
Question 88
Question
Prolactin is important in Reproduction and Growth and Development, but not Osmoregulation
Question 89
Question
What are the reproductive actions of Prolactin in males?
Question 90
Question
What are the reproductive actions of Prolactin in females?
Answer
-
Increase progesterone synthesis
-
Increase oxytocin synthesis
-
Synthesis of casein (milk protein) and fatty acids
-
Formation of uterine wall
-
Osmoregulatory in uterus
-
Hyperprolactinemia= reduced GnRH release and LH production
-
Hyperprolactinemia= increased GnRH release and LH production
Question 91
Question
What characterizes Growth Hormones?
Question 92
Question
Hormones and factors that have an effect on Growth Hormone...
GHRH has a [blank_start]+[blank_end] effect
Somatostatin has a [blank_start]-[blank_end] effect
IGF-1 has a [blank_start]-[blank_end] effect
Hypoglycemia has a [blank_start]+[blank_end] effect
High protein meal has a [blank_start]+[blank_end] effect
Fatty acids have a [blank_start]-[blank_end] effect
Question 93
Question
GH deficiency early in life, and late in life causes respectively...
Answer
-
weakness, low sex drive, and genital atrophy ---- Dwarfism
-
Dwarfism ---- weakness, low sex drive, and genital atrophy
Question 94
Question
Excess GH early in life and later in life cause respectively....
Question 95
Question
What factors effect TSH release?
Answer
-
Temperature
-
TRH
-
T5
-
T4
-
T3
-
Osmoregulation
Question 96
Question
A goiter is a result of iodine deficiency leading to...
Answer
-
High T3, and T4 and high TSH
-
Low T3 and T4 and low TSH
-
High T3 and T4 and high TSH
-
Low T3 and T4 and High TSH
Question 97
Question
Steps in the synthesis of Thyroid Hormones
[blank_start]3[blank_end]. Iodination of tyrosyl residues of thyroglobin molecules to form monoiodotyrosine (MIT) and diiodotyrosine (DIT)
[blank_start]1[blank_end]. Iodide trapping by active transport (symport with Na+)
[blank_start]4[blank_end]. Oxidative coupling of iodinated tyrosines-> form mainly T4 and less T3 (stored in colloid space)
[blank_start]2[blank_end]. Oxidation of iodide (I-) to iodine (I2) by iodide peroxidase
Question 98
Question
T3 is produced in tissues outside the thyroid gland from [blank_start]deiodination[blank_end] of T4 in liver kidneys, anterior pituitary, cerebral cortex, and brown fat.
Answer
-
deiodination
-
iodination
-
hydrolyzation
-
lysis
Question 99
Question
Thyroid hormones are lipophobic and thus use intracellular receptors
Question 100
Question
What are the effects of TH on various target tissues?
Question 101
Question
Basal metabolic rate is the minimum amount of energy to keep the body working properly, what specific hormone has a positive effect on BMR?
Question 102
Question
Thermogenesis with relation to TH:
Cold->neuroendocrine reflex->[blank_start]increased[blank_end] hypothalamic TRH->increased [blank_start]TSH[blank_end]->increased [blank_start]T4[blank_end] and [blank_start]T3[blank_end] production->thermogenesis
Answer
-
increased
-
decreased
-
TSH
-
TRH
-
TH
-
T4
-
T5
-
T3
-
T2
Question 103
Question
What hormone is the key regulator of reproduction in vertebrates
Question 104
Question
What characterizes the hormone GnRH?
Answer
-
Synthesis in neurosecratory neurons
-
Free floating in the extracellular fluid
-
Secreted in a pulsatile manner
-
Peptide hormone
-
Amino Acid hormone
Question 105
Question
GnRH acts to stimulate or suppress the reproductive process and cell division
Question 106
Question
________ stimulates _______ peptin and that stimulates __________.
Answer
-
GnRH, Kiss, Estrogen
-
Kiss, Estrogen, GnRH
-
Estrogen, Kiss, GnRH
-
Kiss, GnRH, Estrogen
Question 107
Question
Birth control pills are made up of only estrogen
Question 108
Question
Binding proteins are critical in maintaining...
Question 109
Question
Effects of gonadal steroids in women...
Answer
-
Estrogen can increase LH secretion
-
Estrogen effects mediated my Kiss Peptins
-
Inhibit the ovulatory surge of gonadotropins (mainly LH)
-
Combination of estrogen and progesterone inhibit LH and FSH production
Question 110
Question
What two gonadal peptides shut off and activate GnRH production from pituitary?
Question 111
Question
Activin and inhibin are produced in the ovary and testis and are involved in the specific regulation of FSH where they stimulate of inhibit the secretion of FSH without effecting LH.
Question 112
Question
What are the two phases of the menstrual cycle?
Answer
-
Luteal
-
Shedding
-
Stimulating
-
Follicular
Question 113
Answer
-
Maturation of oocyte and ovulation
-
Result of stimulaiton from GnRH
-
Surge result in maturation/ovulation
-
Produce estrogen and progesterone
Question 114
Answer
-
Estrogen->Kiss peptins->GnRH->LH&FSH
-
Produced by corpus luteum
-
Build up caused by progesterone
-
Regression of corpus luteum
Question 115
Question
If pregnancy occurs chorionic gonadotroph (sectreted from [blank_start]placenta[blank_end]) secretions prolong the [blank_start]progesterone[blank_end] secretion and maintains pregnancy
Answer
-
Placenta
-
Corpus Luteum
-
Hyothalamus
-
progesterone
-
estrogen
-
LH
-
GnRH
Question 116
Question
All steroid hormones are derived from [blank_start]cholesterol[blank_end] and are lipid soluble therefore must utilize [blank_start]binding[blank_end] proteins
Answer
-
cholesterol
-
amino acids
-
glucose
-
fatty acids
-
binding
-
pairing
-
matching
-
protecting
Question 117
Question
In the steroid hormone synthesis pathway:
-The Steroidogenic acute regulatory protein ([blank_start]StAR[blank_end]) moves [blank_start]cholesterol[blank_end] into the inner membrane of the [blank_start]mitochondria[blank_end] (shuttling protein)
-The [blank_start]cytrochrome[blank_end] P450 side chain cleavage is the rate limiting enzyme
-[blank_start]Aromatase[blank_end] is used in the conversion from androstenedione and testosterone to estrogen and Estradiol
-The only determination of product=[blank_start]specific[blank_end] enzymes along the pathway
Answer
-
StAR
-
cholesterol
-
amino acids
-
glucose
-
mitochondria
-
golgi body
-
ER
-
Cell
-
cytrochrome
-
Aromatase
-
Aromylase
-
Convertase
-
specific
-
major
-
selective
Question 118
Question
Androgens experience only [blank_start]-[blank_end] feedback
Estrogen experiences only [blank_start]+[blank_end] feedback
Question 119
Question
Which of these options correctly pairs pancreatic hormones with the type of cell that produces them?
Answer
-
Insulin- beta cells
-
Insulin- alpha cells
-
Glucagon- alpha cells
-
Glucagon- beta cells
Question 120
Question
Which of these hormones are produced in the adrenal glands?
Answer
-
Insulin
-
Glucocorticoids
-
Glucagon
-
Adrenalin
Question 121
Question
[blank_start]Glycogenolysis[blank_end]= the conversion of glycogen to glucose
[blank_start]Gluconeogenesis[blank_end]= the synthesis of new glucose from non-carbohydrate substrates (a.as or glycerol)
Answer
-
Glycogenolysis
-
Glycogen Synthesis
-
Gluconeogenesis
-
Glycolysis
Question 122
Answer
-
Increases blood glucose
-
Is a hypoglycemic hormone
-
Enhanced cellular storage of glucose
-
Opposes fat synthesis
-
Acts on RTK receptors
-
Decreases solute transport
-
Increase oxidation of glucose in adipose tissues to produce ATP
-
Increase gycogenesis in mainly muscle
-
Decrease protein synthesis as a result of increased a.a transport
Question 123
Question
Type 1 Diabetes is an autoimmune disorder that is...
Answer
-
Insulin independent
-
Insulin dependent
-
Insulin acting
-
Insulin overloading
Question 124
Question
What hormones oppose insulin action?
Answer
-
Estrogen
-
Glucagon
-
Testosterone
-
Cortisol
-
Adrenaline
-
Progesterone
Question 125
Question
Glucagon is a....
Answer
-
Hyperglycemic hormone
-
Enhances the actions of insulin
-
Acts on liver cells to increase glucose production
-
Decrease glucose levels in circulation
Question 126
Question
What actions are characteristic of Glucagon?
Question 127
Question
What type of hormones are associated with the Adrenal Medulla?
Answer
-
Corticosteroids
-
Catecholamines
-
Growth Hormones
-
Steroid hormones
Question 128
Question
Within the Catecholamine synthesis pathway:
[blank_start]Phenylalanine[blank_end] is broken down by phenylalanine hydroxylase to make [blank_start]Tyrosine[blank_end] (the backbone for all amine hormones) is then broken down by Tyrosine hydroxylase (rate limiting enzyme) to produce [blank_start]dihydroxyphenylalanine[blank_end] (DOPA) which in turn in broken down to form Dopamine, then [blank_start]Norepinepherine[blank_end] which is lastly broken down by [blank_start]Phenylethanolamine-N-methyltransferase[blank_end] (PNMT) to form [blank_start]Epinepherine[blank_end].
Question 129
Question
Andregenic receptors are sensitive to both E and NE although which one is more responsive to alpha and which to beta receptors?
Answer
-
alpha- E, beta- NE
-
alpha-NE, beta- E
Question 130
Question
Epinephrine has a more generalized bodily response when it comes to an emergency response than Norepinepherine.
Question 131
Question
Adrenalin is a hyperglycemic hormone because it...
Answer
-
Stimulates ACTH release
-
Stimulates insulin release
-
Stimulates glycogenolysis and gluconeogenesis
-
Inhibits glucagon release
Question 132
Question
The Adrenal cortes produces:
[blank_start]Mineralocorticoids[blank_end] such as aldosterone in the zona [blank_start]glomerulosa[blank_end]
[blank_start]Glucocorticoids[blank_end] such as cortisol in the zona [blank_start]fasciculata[blank_end]
[blank_start]Gondaocorticoids[blank_end] such as androgens in the zona [blank_start]reticularis[blank_end]
The only thing that differentiates what is produced at each layer are the [blank_start]enzymes[blank_end] that occur in the different areas
Answer
-
Mineralocorticoids
-
glomerulosa
-
Glucocorticoids
-
fasciculata
-
Gondaocorticoids
-
reticularis
-
enzymes
-
lipids
-
components
Question 133
Question
Chromaffin is the tissue in the medulla that secretes Catecholamine hormones
Question 134
Question
The release and action of corticosteroids (steroid hormones) takes longer because...
Question 135
Question
In the Hypothalamo-Hypophyseal-Adrenal axis:
The [blank_start]hypothalamus[blank_end] produces [blank_start]corticotropin releasing hormone[blank_end] (CRH) that acts on the [blank_start]pituitary[blank_end] which releases [blank_start]ACTH[blank_end] which binds to the [blank_start]adrenal cortex[blank_end] through the melanocortin 2 receptor ([blank_start]MC2R[blank_end]) which finally produces [blank_start]corticosteroids[blank_end].
Question 136
Question
Glucocorticoids....
Answer
-
increase the avalability of glucose
-
inhibit the breakdown of proteins and fats for their conversion to carbohydrates for gluconeogenesis
-
inhibits the uptake of glucose from certain cells