Question 1
Question
[blank_start]Diabetes Mellitus (DM)[blank_end] is actually a group of metabolic disorders characterized by hyperglycemia which results from defect in secretion of insulin, action of insulin, or both
Question 2
Question
What counterregulatory hormones are responsible for the decrease in insulin release when blood glucose levels drop? (select all that apply)
Answer
-
Glucagon
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growth hormone
-
glucocorticoids
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epinephrine
-
thyroid hormone
Question 3
Question
[blank_start]DDP-IV[blank_end] enzymes are responsible for the break down of gut incretins GLP-1 and GIP.
Question 4
Question
Insulin is secreted from ___________.
Answer
-
alpha cells
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beta cells
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gamma cells
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delta cells
Question 5
Question
What would you check to see if a person is in fact making insulin?
Answer
-
preproinsulin
-
proinsulin
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C peptide
Question 6
Question
Fill in the blanks
Answer
-
GLUT
-
potassium
-
depolarization
Question 7
Question
Meal ingestion causes the rapid release of insulin and [blank_start]amylin[blank_end] from the pancreas.
Answer
-
amylin
-
proinsulin
-
c peptide
Question 8
Question
Type 1 DM is the abosulte deficiecny of amylin and insuilin.
Question 9
Question
Which of the following is NOT an effect of amylin?
Question 10
Question
In glucose homeostasis, 40% of gluconeogeneiss occurs in the [blank_start]kidneys[blank_end] and reabsoprtion of glucose occurs in the [blank_start]proximal tubule[blank_end].
Question 11
Question
Fill in the blanks with appropriate values used to diagnose a patient with PRE-DIABETES according to ADA guidelines?
FPG/IFG: [blank_start]100-125mg/dL[blank_end]
2-hr OGTT/IGT: [blank_start]140-199mg/dL[blank_end]
A1c: [blank_start]5.7% - 6.4%[blank_end]
Answer
-
50-100mg/dL
-
100-125mg/dL
-
150-200mg/dL
-
200-225mg/dL
-
100-125mg/dL
-
140-199mg/dL
-
220=250mg/dL
-
5.7% - 6.4%
-
7% -7.5%
-
8% - 8.5%
Question 12
Question
β-cell destruction usually leading to absolute insulin and amylin deficiency.
Question 13
Question
“Progressive insulin secretory defect (β-cell dysfunction) on the background of insulin resistance.
Answer
-
Type 1 DM
-
Type 2 DM
-
Gestational DM
Question 14
Question
Diabetes diagnosed during pregnancy that IS NOT clearly overt diabetes
Answer
-
Type 1 DM
-
Type 2 DM
-
Gestational Diabetes
Question 15
Question
Fill in the table below
Question 16
Question
Which of the following below are symptoms of HYPERglycemia? (select all that apply)
Answer
-
polydipsia
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polyuria
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polyphagia
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dry skin
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blurry vision
-
drowsy
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slow healing wounds
Question 17
Question
During pregnanacy, the placenta can produce hormones that contribute to insulin resistance.
Question 18
Question
Criteria for the diagnosis of diabetes;
(1) A1C > [blank_start]6.5[blank_end]%
(2) FPG > [blank_start]126[blank_end] mg/dL
(3) 2-hr PG > [blank_start]200[blank_end] mg/dL after a 75 gram oral glucose tolerance test (OGTT)
Question 19
Question
Acanthosis Nigricans is associated with ....
Question 20
Question
Children with BMI precentile of [blank_start]85[blank_end] or greater should be considered for screening for T2DM
Question 21
Question
When should pregnant women without overt DM should be screeened for gestational diabetes mellitus?
Answer
-
15-20 weeeks
-
20-22 weeks
-
24-28 weeks
-
30-33 weeks
Question 22
Question
Gestational diabetes mellitus should be tested for a second time 2-3 weeks post partum.
Question 23
Question
Which of the following are complications of DM in pregnancy (select all that apply)
Answer
-
gestational HTN
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Preecalmpsia
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Gestational HYPOtension
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infections
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ketoacidosis
-
polyhrdramnios
-
preterm labor
-
seizures
Question 24
Question
Fill in the appropriate values for the ACOG: Carpenter and Coustan 100mg OGTT 3hr (mg/dL) which is used in the diagnosis of GDM.
Fasting: [blank_start]95[blank_end]
1 hour: [blank_start]180[blank_end]
2 hours: [blank_start]155[blank_end]
3 hours: [blank_start]140[blank_end]
Question 25
Question
What are the glycemic goal for patients with GDM and preexisting DM?
(1) Fasting less than or equal to [blank_start]95[blank_end] mg/dL
(2) 1-hr PP less than or equal to [blank_start]140[blank_end] mg/dL
(3) 2-hr PP less than or equal to [blank_start]120[blank_end] mg/dL
Question 26
Question
During pregnancy an A1C of [blank_start]6-6.5[blank_end] % is the reccomeneded target in the second and third trimester but < [blank_start]6[blank_end] % may be optimal.
Question 27
Question
During pregnancy insulin resistance decreases as pregnancy progresses
Question 28
Question
Hypoglycemia is usually defined as < 70 mg/dl but in pregnancy BG is often allowed to be than [blank_start]60[blank_end] mg/dL
Question 29
Question
Indicate which insulins and oral medications are utilized in the treatment of diabetes during pregnancy?
Answer
-
Metformin
-
Lantus
-
Glargine
-
NPH
-
Regular insulin
-
Glyburide
-
Apidra
Question 30
Question
[blank_start]Insulin[blank_end] is the first-line agent recommended for treatment of GDM in the U.S
Question 31
Question
[blank_start]Glyburide[blank_end] may be inferior to metformin and insulin due to increased risk of neonatal hypoglycemia and macrosomia
Question 32
Question
[blank_start]Aspart[blank_end] and [blank_start]Lispro[blank_end] are the only rapid-acting insulins approved during pregnancy
Question 33
Question
[blank_start]Detemir[blank_end] is the only long-acting basal insulin utilized to treat diabetes in pregnancy
Question 34
Question
What are the glucose levels for insulin initiation in GDM
Fasting PG less than or equal to [blank_start]105[blank_end] mg/dL
1-hours postprandial plasma glucose less than or equal to [blank_start]155[blank_end] mg/dL
2-hour postprandial plasma glucose less than or equal to [blank_start]130[blank_end] mg/dL
Question 35
Question
T1DM will require insulin during labor while most do not require insulin during labor and delivery with GDM
Question 36
Question
What immunizations are reccomended for diabetic patients?
Answer
-
influnenza
-
pneumococal
-
hepatitis B
Question 37
Question
Hypoglycemia is indicated with a BG of less than [blank_start]70[blank_end] mg/dL
Question 38
Question
1) If blood glucose (BG) is less than 70 mg/dL, you should give [blank_start]15[blank_end] grams of carbs and recheck the blood glucose after 15 minutes.
2) If blood glucose is less than 50 mg/dL , you should give [blank_start]30[blank_end] grams of carbs and recheck the blood glucose after 15 minutes
Question 39
Question
15g is equal to:
[blank_start]1[blank_end] tablespoon of sugar, [blank_start]3-4[blank_end] hard candies, [blank_start]4[blank_end] oz regular fruit juice, [blank_start]6[blank_end] oz regular soda, 3-4 glucose tablets, 6 lifesvavers save a life
Answer
-
1
-
3-4
-
4
-
6
-
3-4
-
1
-
4
-
6
-
4
-
1
-
3-4
-
6
-
6
-
4
-
1
-
3-4
Question 40
Question
Which of the following should be part of the sick day management plan?
Answer
-
Check BG more frequently
-
Try to keep BG < 200 mg
-
Contiune basal insulin
-
Stay hydrated
-
use liquid carbohydrates to keep BG stable if unable to keep food down or having frequent or severe drops in BG
-
May need to hold prandial insulin or some oral medications if unable to keep down any carbohydrates.
Question 41
Question
What are the possible causes of DKA?
Answer
-
Exacerbated by an increase in counterregulatory hormones – hyperglycemic crisis
-
Insulin deficiency promotes lipolysis and metabolism of FFA to β-hydroxybutyrate, acetoacetic acid, and acetone in the liver
-
Excess glucagon enhance gluconeogenesis and impairs peripheral ketone utilization
-
Reduction in the effective circulating insulin with a concomitant elevation of counter-regulatory hormones
Question 42
Question
What are the causes of HHS?
Answer
-
Excess glucagon enhance gluconeogenesis and impairs peripheral ketone utilization
-
Reduction in the effective circulating insulin with a concomitant elevation of counter-regulatory hormones
-
Consistently elevated blood glucose concentration (sometimes weeks) in the face of reduce fluid intake
-
Most commonly preceded by infection or other serious illness
Question 43
Question
Complete the algorithhm
Answer
-
0.9% NaCl
-
0.45% NaCl
-
0.9% NaCl
-
200
-
300
-
0.1
-
0.14
-
0.14
Question 44
Question
Complete the algortithm
Question 45
Question
In hospital care, treat if the blood glucose is above [blank_start]180[blank_end] mg/dL with a goal between [blank_start]140-180[blank_end] mg/dL.
Question 46
Question
In what conditions should you consider lowering the dose of basal insulin by 20%?
Question 47
Question
Turn off insulin infusion [blank_start]2[blank_end] hours after administration of SubQ basal insulin
Question 48
Question
Fill in the Tabel below
Answer
-
Type 1
-
Type 2
-
Hours to days
-
Days to weeks
-
> 250
-
>600
-
< 7.35
-
7.35-7.45
-
Present
-
Absent or very little
-
< 320
-
> 320
-
Type 2
-
Type 1
-
Hours to days
-
Days to weeks
-
> 250
-
> 600
-
< 7.35
-
7.35 - 7.45
-
Present
-
Absent or very little
-
< 320
-
> 320