Question 1
Question
The secondary stage of syphilis
Answer
-
is when the patient is no longer infectious to others.
-
occurs within 10 days of the primary stage.
-
is a time when the pathogen enters and multiplies in the blood.
-
has no symptoms.
-
is when gummas develop in tissues.
Question 2
Question
During which stage of syphilis does fever, lymphadenopathy, and a red to brown rash occur?
Question 3
Question
Permanent cardiovascular and neurological damage is seen in which stage of syphilis?
Question 4
Question
Treponema, Borrelia, and Leptospira are all
Answer
-
obligate parasites requiring host cells.
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curved rods.
-
transmitted by arthropod vectors.
-
spirochetes.
-
bacteria without cell walls.
Question 5
Question
Yaws, Pinta, and Bejel are all diseases that
Answer
-
are slow, progressive skin diseases that can spread to deep tissues.
-
are sexually transmitted.
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are caused by arthropod vectors.
-
are caused by Vibrio species
-
are respiratory tract infections.
Question 6
Question
Infected animals shed Leptospira interrogans in their
Answer
-
feces
-
blood
-
urine
-
respiratory secretions
-
saliva
Question 7
Question
Leptospirosis has all the following characteristics except
Answer
-
most common in cattle, horses, pigs, and dogs
-
pathogen is a spirochete
-
infects kidneys, liver, brain, eyes
-
humans acquire it by contact with abraided skin or mucous membranes
-
can be transmitted by animal bites
Question 8
Question
Relapsing fever involves
Answer
-
soft-bodied ticks transmitting Borrelia hermsii.
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initial symptoms of fever, headache, fatigue.
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late symptoms of vomiting, muscle aches, damage to liver, spleen, heart and kidneys.
-
human body louse transmitting Borrelia recurrentis.
-
All of the choices are correct.
Question 9
Question
The causative agent of Lyme disease is
Answer
-
Ixodes scapularis
-
Borrelia hermsii
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Borrelia burgdorferi
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Ixodes pacificus
-
Leptospira interrogans
Question 10
Question
Erythema migrans, a bull's-eye rash, at the portal of entry is associated with
Question 11
Question
The Argyll Robertson pupil that is fixed and small, and does not react to light but does accommodate for focusing is associated with
Question 12
Question
The white-footed mouse, deer, and deer ticks are important to maintaining the enzootic transmission cycle associated with
Question 13
Question
Control of rodent populations is important for preventing
Question 14
Question
Lyme disease involves
Answer
-
early symptoms of fever, headache, stiff neck.
-
crippling polyarthritis and cardiovascular and neurological problems.
-
people having contact with wooded or forested areas.
-
treatment with antimicrobics.
-
All of the choices are correct.
Question 15
Question
The RPR, VDRL, MHA-TP, FTA-ABS, and TPI tests are used to diagnose
Question 16
Question
The virulence of Vibrio cholerae is due to its
Question 17
Question
Cholera symptoms are
Answer
-
copious watery diarrhea
-
loss of blood volume
-
acidosis, sunken eyes, thirst
-
hypotension, tachycardia, shock
-
All of the choices are correct
Question 18
Question
The most immediate and important treatment needed to prevent death in Cholera victims is
Question 19
Question
An organism found in coastal waters that causes a food infection and gastroenteritis due to a variety of contaminated raw and undercooked seafood is
Answer
-
Chlamydia trachomatis
-
Vibrio parahaemolyticus
-
Vibrio cholerae
-
Campylobacter jejuni
-
Helicobacter pylori
Question 20
Question
In patients with diabetes or liver disease, ingestion of raw oysters contaminated with this organism can lead to death
Answer
-
Vibrio vulnificus
-
Vibrio parahaemolyticus
-
Vibrio cholerae
-
Campylobacter jejuni
-
Helicobacter pylori
Question 21
Question
"Rice water stools" are associated with disease caused by this organism:
Answer
-
Vibrio vulnificus
-
Vibrio parahaemolyticus
-
Vibrio cholerae
-
Campylobacter jejuni
-
Helicobacter pylori
Question 22
Question
Helicobacter pylori causes
Question 23
Question
Which is NOT a characteristic of Helicobacter pylori?
Question 24
Question
All of the following are characteristics of Campylobacter jejuni except
Answer
-
it is transmitted through ingestion of contaminated chicken, meat, milk, and water.
-
it causes fever and a watery to bloody diarrhea.
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it infects the stomach.
-
it produces an enterotoxin that stimulates diarrhea.
-
it has gram negative curved rods with darting motility.
Question 25
Question
Characteristics of rickettsias include
Answer
-
obligate parasites requiring host cells for growth.
-
arthropods serve as life cycle hosts and vectors.
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gram negative coccobacilli.
-
host cells are required for ATP metabolism.
-
All of the choices are correct.
Question 26
Question
The pathogenesis of rickettsial infections often involves infection of
Question 27
Question
Which is mismatched?
Answer
-
epidemic typhus – body louse feces
-
murine typhus – flea feces
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rickettsial pox – mite bite
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Rocky Mountain spotted fever – tick bite
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human ehrlichiosis – flea bite
Question 28
Question
Rocky Mountain spotted fever
Answer
-
is seen in highest numbers along the west coast.
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is transmitted by Ixodes ticks
-
has symptoms that include fever, headache and rash.
-
never has severe complications.
-
All of the choices are correct.
Question 29
Question
All of the following pertain to erhlichiosis except
Answer
-
it is transmitted by Amblyomma and Ixodes ticks.
-
it causes infection of monocytes.
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it causes infection of granulocytes.
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has symptoms that include fever, headache, and muscle pains.
-
the disease is showing a decreased incidence.
Question 30
Question
Which is incorrect regarding Q fever?
Answer
-
transmitted by lice
-
pathogen produces resistant spores
-
humans infected from unpasteurized milk and airborne spread
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causes fever, muscle aches, rash, and sometimes pneumonia
-
is a zoonosis
Question 31
Question
Which is mismatched?
Answer
-
Rickettsia rickettsii – epidemic typhus
-
Coxiella burnetii – Q fever
-
Bartonella quintana – trench fever
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Bartonella henselae – cat scratch disease
-
Rickettsia typhi – endemic (murine) typhus
Question 32
Question
The following are characteristics of Chlamydias except
Answer
-
gram negative
-
obligate parasites that need host cells for growth
-
elementary bodies are the infectious form
-
elementary bodies lack enzyme systems for making ATP
-
reticulate bodies differentiate into elementary bodies
Question 33
Question
Chlamydia trachomatis causes
Answer
-
nongonococcal urethritis (NGU) in males.
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cervicitis in females.
-
congenital and adult inclusion conjunctivitis.
-
ocular trachoma.
-
All of the choices are correct.
Question 34
Answer
-
caused by Chlamydia pneumoniae.
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a zoonosis of certain types of birds
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a mild, upper respiratory tract illness.
-
has humans as a reservoir for the pathogen.
-
All of the choices are correct.
Question 35
Question
Lymphogranuloma venereum is caused by
Question 36
Question
Which is incorrect about Mycoplasma pneumoniae?
Answer
-
has birds as a reservoir
-
common cause of primary atypical pneumonia
-
initially causes fever, malaise, sore throat, headache
-
after 2 to 3 weeks develops into an unproductive cough and earache
-
is a bacterial cell without a cell wall
Question 37
Question
Oral flora bacteria on the tooth surface
Answer
-
develop a biofilm.
-
use fimbriae and slime layers to adhere.
-
include streptococci that metabolize sucrose, produce sticky glucans, and form plaque.
-
lactobacilli and streptococci ferment carbohydrates and produce acids that cause caries.
-
All of the choices are correct.
Question 38
Answer
-
primarily caused by anaerobic oral flora.
-
erosion of tooth enamel causing a lesion.
-
caused by Streptococcus mutans
-
also called NUG.
-
None of the choices are correct.
Question 39
Question
Ureaplasma urealyticum is implicated in which of the following?
Question 40
Question
All of the following can positively influence the structure of tooth enamel except
Answer
-
fluoride
-
lysozyme in saliva
-
antibodies in saliva
-
refined sugar
-
genetics.
Question 41
Question
Treponema vincentii, Bacteroides forsythus, and fusobacteria synergistically are involved in which infection?
Question 42
Question
Which of the following distinguishes syphilis from yaws?
Answer
-
Syphilis is caused by a spirochete
-
Syphilis has a primary, secondary, and tertiary stages.
-
Syphilis is sexually transmitted.
-
Syphilis is treated with antibiotics.
-
Syphilis is a slow and progressive disease.
Question 43
Question
Which of the following are other names for yaws?
Question 44
Question
Hutchinson's teeth are
Answer
-
a symptom of untreated Lyme disease.
-
a symptom of untreated periodontal disease.
-
a symptom of ANUG.
-
a symptom of congenital syphilis.
-
a symptom of congenital Chlamydia trachomatis.
Question 45
Question
The tertiary stage of syphilis
Answer
-
is when gummas develop in tissues.
-
is when the patient is highly infectious to others.
-
occurs within 10 days of the primary stage.
-
has no symptoms.
-
is when a chancre develops.
Question 46
Question
Which is incorrect about Lyme disease?
Answer
-
It is a new disease that started in Lyme, Connecticut.
-
Its reservoirs are mice and deer
-
It is transmitted by ticks.
-
It is nonfatal.
-
It can slowly progress and mimic rheumatoid conditions.
Question 47
Question
Which of the following diseases could be prevented with proper sewage disposal and water purification?
Question 48
Question
Which is incorrect about Leptospirosis?
Answer
-
It can be avoided by not swimming in livestock watering ponds.
-
A vaccine is not available.
-
Its principle targets are the kidneys, liver, brain, and eyes.
-
It is a zoonosis.
-
Weil's syndrome occurs during the second phase of the disease.
Question 49
Question
Which bacteria could be responsible for hemolytic uremic syndrome (HUS)?
Question 50
Question
Which of the following is not correct concerning Legionnaires disease?
Answer
-
L. pneumophila lives in close associations with free-living amebas.
-
The disease is communicable from person to person.
-
Symptoms include cough, diarrhea, and abdominal pain.
-
. It is more common in males over 50 years of age.
-
Cases have been traced to the fallout from the Mount Saint Helen's volcano.
Question 51
Question
Which of the following is not correct concerning the plague?
Answer
-
Mice, voles and other rodents are primary long-term reservoirs.
-
Strains of the plague bacillus are less virulent today as in the Middle Ages
-
It is transmitted by flea vectors.
-
Less than 10 cases per year occur in the US.
-
The etiological agent is Yersinia pestis.
Question 52
Question
What is the usual cause of pseudomembranous colitis?
Answer
-
improperly home-preserved foods containing botulin toxin
-
eating unpasteurized dairy containing Listeria monocytogenes
-
handling infected animals contaminated with E. rhusiopathiae
-
therapy with broad-spectrum antibiotics leading to superinfection by C. difficile
-
living in close contact with someone infected with C. perfringens
Question 53
Question
Which of the following may be recommended for treating gangrene?
Answer
-
debridement of the wound
-
hyperbaric chamber
-
amputation of affected limb
-
rigorous cleansing of deep wounds
-
All of the choices are correct.
Question 54
Question
Mild, uncomplicated cases of pseudomembranous colitis may be treated by
Answer
-
debridement
-
wound cleansing
-
vancomycin for several weeks
-
withdrawal of antibiotics and replacement of lost fluids and electrolytes
-
All of the choices are correct
Question 55
Question
Viruses have all the following except
Question 56
Question
Host cells of viruses include
Question 57
Question
The core of every virus particle always contains
Answer
-
DNA
-
capsomers
-
enzymes
-
DNA and RNA
-
either DNA or RNA
Question 58
Question
Classification of viruses into families involves determining all the following characteristics except
Question 59
Question
Which of the following represents a virus family name?
Answer
-
Herpes simplex virus
-
Herpesviridae
-
Picornavirus
-
Enterovirus
-
Hepatitis B virus
Question 60
Question
Virus capsids are made from subunits called
Answer
-
envelopes
-
spikes
-
capsomeres
-
prophages
-
peplomers
Question 61
Question
Helical and icosahedral are terms used to describe the shapes of a virus
Answer
-
spike
-
capsomere
-
envelope
-
capsid
-
core
Question 62
Question
Which of the following is correct about viruses?
Question 63
Question
All of the following pertain to virus envelopes except they
Answer
-
gained as a virus leaves the host cell membrane.
-
gained as a virus leaves the nuclear membrane.
-
contain special virus proteins.
-
help the virus particle attach to host cells.
-
located between the capsid and nucleic acid.
Question 64
Question
Which of the following is not associated with every virus?
Answer
-
envelope
-
capsomers
-
capsid
-
nucleic acid
-
genome
Question 65
Question
These structures are used by bacteriophages to attach to host cell receptors
Question 66
Question
Which is incorrect about prophages?
Answer
-
present when the virus is in lysogeny
-
formed when viral DNA enters the bacterial chromosome
-
replicated with host DNA and passed on to progeny
-
cause lysis of host cells
-
occur when temperate phages enter host cells
Question 67
Answer
-
include the poxviruses
-
infect Escherichia coli cells
-
enter host cells by engulfment
-
have helical capsids
-
All of the choices are correct.
Question 68
Question
The correct sequence of events in viral multiplication is
Answer
-
penetration, replication, maturation, adsorption, assembly, release.
-
replication, penetration, maturation, assembly, absorption, release.
-
adsorption, penetration, replication, maturation, assembly, release
-
assembly, maturation, replication, release, penetration, adsorption.
-
adsorption, release, maturation, replication, assembly, penetration.
Question 69
Question
The event that occurs in bacteriophage multiplication that does not occur in animal virus replication is
Answer
-
adsorption to the host cells
-
injection of the viral nucleic acid into the host cell
-
host cell synthesis of viral enzymes and capsid proteins
-
assembly of nucleocapsids
-
replication of viral nucleic acid
Question 70
Question
Viruses acquire envelopes around their nucleocapsids during
Answer
-
replication
-
assembly
-
adsorption
-
release
-
penetration
Question 71
Question
Which of the following will not support viral cultivation?
Answer
-
live lab animals
-
embryonated bird eggs
-
primary cell cultures
-
continuous cell cultures
-
blood agar
Question 72
Question
In general, most DNA viruses multiply in the host cell's _____, while most RNA viruses multiply in the host cell's _____.
Question 73
Question
Host range is limited by
Answer
-
type of nucleic acid in the virus
-
age of the host cell
-
type of host cell receptors on cell membrane
-
size of the host cell
-
All of the choices are correct.
Question 74
Question
The virus-induced, specific damage to the host cell that can be seen in a light microscope is called
Answer
-
lysogeny
-
budding
-
plaques
-
cytopathic effects
-
pocks
Question 75
Question
Visible, clear, well-defined patches in a monolayer of virus-infected cells in a culture are called
Answer
-
lysogeny
-
budding
-
plaques
-
cytopathic effects
-
pocks
Question 76
Question
Viral growth in bird embryos can cause discrete, opaque spots in the embryonic membranes called
Answer
-
lysogeny
-
budding
-
plaques
-
cytopathic effects
-
pocks
Question 77
Question
Viruses that cause infection resulting in alternating periods of activity with symptoms and inactivity without symptoms are called
Answer
-
latent
-
oncogenic
-
prions
-
viroids
-
delta agents
Question 78
Question
Which of the following is a type of cytopathic effect?
Answer
-
inclusions in the nucleus
-
multinucleated giant cells.
-
inclusions in the cytoplasm
-
cells round up
-
All of the choices are correct.
Question 79
Question
Uncoating of viral nucleic acid
Answer
-
does not occur in bacteriophage multiplication
-
involves enzymatic destruction of the capsid
-
occurs during penetration in the multiplication cycle
-
occurs before replication
-
All of the choices are correct
Question 80
Question
Infectious protein particles are called
Answer
-
viroids
-
phages
-
prions
-
oncogenic viruses
-
spikes
Question 81
Question
Infectious naked strands of RNA are called
Answer
-
viroids
-
phages
-
prions
-
oncogenic viruses
-
spikes
Question 82
Question
Creutzfeld-Jacob disease is
Answer
-
caused by a chronic latent virus
-
initiated by an oncogenic virus
-
caused by a viroid
-
a spongiform encephalopathy of humans
-
also called "mad cow disease".
Question 83
Question
Satellite viruses are
Answer
-
also called viroids
-
dependent on other viruses for replication
-
the cause of spongiform encephalopathies
-
significant pathogens of plants
-
All of the choices are correct.
Question 84
Question
All of the following is correct about treating viral diseases except
Answer
-
viruses are killed by the same antibiotics that kill bacteria
-
many antiviral drugs block viral replication
-
many antiviral drugs cause severe side effects
-
interferons show potential for treating and preventing viral infections
-
All of the choices are correct.
Question 85
Question
The capsomers are made of
Answer
-
DNA
-
RNA
-
Lipids
-
Protein
-
Carbohydrate
Question 86
Question
Viruses that consist of only a nucleocapsid are considered
Answer
-
simple viruses
-
complex viruses
-
naked viruses
-
viroids
-
incomplete viruses
Question 87
Question
The nucleocapsid consists of
Answer
-
the capsomers assembled into the capsid
-
the nucleic acid of the virus only
-
the nucleic acid along with the capsid
-
the envelope and capsid
-
the envelope, nucleic acid and caspid
Question 88
Question
Which of the following parts of a virus is not always present?
Question 89
Question
When a virus enters a lysogenic phase, it means
Answer
-
the virus is integrated into the DNA of the host cell and is latent.
-
the virus is bursting through the host cell membrane.
-
the virus is starting biosynthesis of its nucleic acid.
-
the virus will remain in circulation and not continue infecting its host.
-
the number of viruses in the host is decreasing as the immune system becomes effective.
Question 90
Question
All of the following are characteristics of viruses except
Answer
-
they can be crystallized.
-
they often have a geometric capsid
-
they have a viscous fluid inside their capsids
-
they can cause fatal diseases.
-
they can cause mild diseases.